• Journal of Animal Science and Technology
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• 제57권12호
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• pp.44.1-44.9
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• 2015

Background: Heat shock proteins play an important role in protection from stress stimuli and metabolic insults in almost all organisms. Methods: In this study, computational tools were used to deeply analyse the physicochemical characteristics and, using homology modelling, reliably predict the tertiary structure of the blunt snout bream (Ma-) Hsp70 and Hsc70 proteins. Derived three-dimensional models were then used to predict the function of the proteins. Results: Previously published predictions regarding the protein length, molecular weight, theoretical isoelectric point and total number of positive and negative residues were corroborated. Among the new findings are: the extinction coefficient (33725/33350 and 35090/34840 - Ma-Hsp70/ Ma-Hsc70, respectively), instability index (33.68/35.56 - both stable), aliphatic index (83.44/80.23 - both very stable), half-life estimates (both relatively stable), grand average of hydropathicity (-0.431/-0.473 - both hydrophilic) and amino acid composition (alanine-lysine-glycine/glycine-lysine-aspartic acid were the most abundant, no disulphide bonds, the N-terminal of both proteins was methionine). Homology modelling was performed by SWISS-MODEL program and the proposed model was evaluated as highly reliable based on PROCHECK's Ramachandran plot, ERRAT, PROVE, Verify 3D, ProQ and ProSA analyses. Conclusions: The research revealed a high structural similarity to Hsp70 and Hsc70 proteins from several taxonomically distant animal species, corroborating a remarkably high level of evolutionary conservation among the members of this protein family. Functional annotation based on structural similarity provides a reliable additional indirect evidence for a high level of functional conservation of these two genes/proteins in blunt snout bream, but it is not sensitive enough to functionally distinguish the two isoforms.

• Nuclear Engineering and Technology
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• 제45권7호
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• pp.827-838
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• 2013

Interaction layer growth between U-Mo alloy fuel particles and Al in a dispersion fuel is a concern due to the volume expansion and other unfavorable irradiation behavior of the interaction product. To reduce interaction layer (IL) growth, a small amount of Si is added to the Al. As a result, IL growth is affected by the Si content in the Al matrix. In order to predict IL growth during fabrication and irradiation, empirical models were developed. For IL growth prediction during fabrication and any follow-on heating process before irradiation, out-of-pile heating test data were used to develop kinetic correlations. Two out-of-pile correlations, one for the pure Al matrix and the other for the Al matrix with Si addition, respectively, were developed, which are Arrhenius equations that include temperature and time. For IL growth predictions during irradiation, the out-of-pile correlations were modified to include a fission-rate term to consider fission enhanced diffusion, and multiplication factors to incorporate the Si addition effect and the effect of the Mo content. The in-pile correlation is applicable for a pure Al matrix and an Al matrix with the Si content up to 8 wt%, for fuel temperatures up to $200^{\circ}C$, and for Mo content in the range of 6 - 10wt%. In order to cover these ranges, in-pile data were included in modeling from various tests, such as the US RERTR-4, -5, -6, -7 and -9 tests and Korea's KOMO-4 test, that were designed to systematically examine the effects of the fission rate, temperature, Si content in Al matrix, and Mo content in U-Mo particles. A model converting the IL thickness to the IL volume fraction in the meat was also developed.

• 한국환경보건학회지
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• 제45권2호
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• pp.173-185
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• 2019

Objectives: The objectives of this study are to evaluate the accuracy and precision of exposure model ECETOC TRA v.3.1 by comparing model predictions with repeated exposure measurements in Korean workplaces and to investigate the applicability of ECETOC TRA to Korean workplace exposure assessment in K-REACH. Methods: Measured values and work conditions for 14 kinds of chemicals collected from exposure field surveys conducted at 10 companies in Korea were utilized for this study. All possible process categories (PROCs) considered to be relevant to each work process classification were selected and applied to ECETOC TRA as major determining parameters. In order to quantify the accuracy of the model, the lack of agreement (bias, relative bias, precision) was calculated and the risk ratios for each exposure situation between estimated and measured were also compared. Results: The estimated values varied between five and 25 times according to the PROCs for all exposure situations (ESs) based on tasks/chemicals. The results showed that most of the estimated values were below the measured values, and just 13 of 53 tasks were above the measured values. The overall bias and precision were $-2.91{\pm}1.62$ with ECETOC TRA, and we found that ECETOC TRA showed a low level of conservatism when applied to Korean workplaces, similar to previous studies. Conclusions: This study demonstrates that the existed PROC codes have limitations in fully covering various ESs in Korea. In order to improve the applicability of ECETOC TRA in K-REACH, the addition of new PROCs for Korean industries are necessary.

• 한국환경복원기술학회지
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• 제17권1호
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• pp.111-122
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• 2014

The provided habitat of many services from natural capital is important. But because most ecosystem services tools qualitatively evaluated biodiversity or habitat quality, this study quantitatively analyzed those aspects using the species distribution model (MaxEnt). This study used location point data of the goat(Naemorhedus caudatus), marten(Martes flavigula), leopard cat(Prionailurus bengalensis), flying squirrel(Pteromys volans aluco) and otter(Lutra lutra) from the 3rd National Ecosystem Survey. Input data utilized DEM, landcover classification maps, Forest-types map and digital topographic maps. This study generated the MaxEnt model, randomly setting 70% of the presences as training data, with the remaining 30% used as test data, and ran five cross-validated replicates for each model. The threshold indicating maximum training sensitivity plus specificity was considered as a more robust approach, so this study used it to conduct the distribution into presence(1)-absence(0) predictions and totalled up a value of 5 times for uncertainty reduction. The test data's ROC curve of endangered mammals was as follows: growing down goat(0.896), otter(0.857), flying squirrel(0.738), marten(0.725), and leopard cat(0.629). This study was divided into two groups based on habitat: the first group consisted of the goat, marten, leopard cat and flying squirrel in the forest; and the second group consisted of the otter in the river. More than 60 percent of endangered mammals' distribution probability were 56.9% in the forest and 12.7% in the river. A future study is needed to conduct other species' distribution modeling exclusive of mammals and to develop a collection method of field survey data.

• 문화기술의 융합
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• 제7권4호
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• pp.807-814
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• 2021

코로나-19로 인해 경제 활동이 낮아지고 주식 시장이 침체하면서 주식 투자를 통해 또 다른 소득을 마련하기 위해 많은 사람이 주식 시장에 뛰어들고 있다. 사람들의 관심이 높아지면서 더 많은 수익을 얻기 위한 주가 분석 연구가 많이 진행되고 있다. 주가는 종목별 변동의 흐름이 다르므로 각 주가 종목별로 독립적이며 일관적으로 분석할 필요가 있다. 이러한 문제를 해결하고자 본 논문에서는 강화학습 기법 중 하나인 Asynchronous Advantage Actor-Critic(A3C)를 이용하여 주가를 분석할 수 있는 모델 및 서비스를 설계 및 구현하였다. 주식 시장 데이터로 종목별 주가 및 국채, 코스피와 같은 외부 요인들을 반영하였다. 또한 웹페이지 제작을 통해 시각화한 정보를 제공하여 투자자들이 투자 기업에 대한 재무제표를 비롯하여 국내외 경제 및 정치의 흐름을 모두 분석하지 않고도 안전한 투자를 할 수 있도록 서비스를 제공한다.

• 비파괴검사학회지
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• 제18권6호
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• pp.445-454
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• 1998

본 연구는 박판 용접부 결함 검출 기법의 확립을 위해서 실시된 기초 연구로서, 전기강판 소재의 모재에 인위적인 결함을 작성하고, 이론 및 시험적 결과를 이용하여 결함을 검출하기 위한 최적의 조건과 임계 검출 결함 크기를 조사한 것이다. 이를 위해서 소재의 dispersion curve를 구하고, 두께 2.4mm의 박판에 대해서 tone burst방식에 의한 초음파 탐상을 실시하였다. 실험적 검토를 행한 결과 840kHz의 가진 주파수와 30도 그리고 85도의 입사각이 최적의 탐상 조건임을 알았다. 한편, 초음파의 속도와 dispersion커브를 비교 검토하여 본 바, 30도의 입사각에서 발생하여 전파하는 초음파는 symmetic mode이고 85도의 입사각에서는 antisymmetric mode의 파가 전파하고 있었다. 결함의 위치와 형상에 따라 반사파의 특성이 다르게 나타나고 있었으며, 특히 표면 결함의 경우에는 antisymmetric 모드의 초음파가 symmetric 모드 보다 높은 반사파 에너지를 나타내고 있었다. 또한 이러한 초음파 모드의 종류와 결함 검출과의 관계에 대해서는 유도파의 구조에 의해서 설명이 가능했다.

• Computers and Concrete
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• 제20권6호
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• pp.635-643
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• 2017

The rehabilitation and strengthening of concrete structures using Fiber-Reinforced Polymer (FRP) materials have been widely investigated. As a priority issue, however, the effect of curing conditions on the bonding behavior between FRP and concrete structures is still elusive. This study aims at developing a prediction model to accurately capture the mode-II interfacial debonding between FRP strips and concrete under different curing conditions. Single shear debonding experiments were conducted on FRP-concrete samples with respect to different curing time t and temperatures T. The J-integral formulation and constrained least square minimization are carried out to calibrate the parameters, i.e., the maximum slip $\bar{s}$ and stretch factor n. The prediction model is developed based on the cohesive model and Arrhenius relationship. The experimental data are then analyzed using the proposed model to predict the debonding between FRP and concrete, i.e., the interfacial shear stress-slip relationship. A Finite Element (FE) model is developed to validate the theoretical predictions. Satisfactory agreements are obtained. The prediction model can be used to accurately capture the bonding performance of FRP-concrete structures.

• Wind and Structures
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• 제13권6호
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• pp.557-580
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• 2010

A new inflow turbulence generation method and a combined dynamic SGS model recently developed by the authors were applied to evaluate the wind effects on 508 m high Taipei 101 Tower. Unlike the majority of the past studies on large eddy simulation (LES) of wind effects on tall buildings, the present numerical simulations were conducted for the full-scale tall building with Reynolds number greater than $10^8$. The inflow turbulent flow field was generated based on the new method called discretizing and synthesizing of random flow generation technique (DSRFG) with a prominent feature that the generated wind velocity fluctuations satisfy any target spectrum and target profiles of turbulence intensity and turbulence integral length scale. The new dynamic SGS model takes both advantages of one-equation SGS model and a dynamic production term without test-filtering operation, which is particular suitable to relative coarse grid situations and high Reynolds number flows. The results of comparative investigations with and without generation of inflow turbulence show that: (1) proper simulation of an inflow turbulent field is essential in accurate evaluation of dynamic wind loads on a tall building and the prescribed inflow turbulence characteristics can be adequately imposed on the inflow boundary by the DSRFG method; (2) the DSRFG can generate a large number of random vortex-like patterns in oncoming flow, leading to good agreements of both mean and dynamic forces with wind tunnel test results; (3) The dynamic mechanism of the adopted SGS model behaves adequately in the present LES and its integration with the DSRFG technique can provide satisfactory predictions of the wind effects on the super-tall building.

• 통합자연과학논문집
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• 제13권4호
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• pp.132-140
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• 2020

With the recent introduction of artificial intelligence (AI) technology, the use of data is rapidly increasing, and newly generated data is also rapidly increasing. In order to obtain the results to be analyzed based on these data, the first thing to do is to classify the data well. However, when classifying data, if only one classification technique belonging to the machine learning technique is applied to classify and analyze it, an error of overfitting can be accompanied. In order to reduce or minimize the problems caused by misclassification of the classification system such as overfitting, it is necessary to derive an optimal classification by comparing the results of each classification by applying several classification techniques. If you try to interpret the data with only one classification technique, you will have poor reasoning and poor predictions of results. This study seeks to find a method for optimally classifying data by looking at data from various perspectives and applying various classification techniques such as LDA and QDA, such as linear or nonlinear classification, as a process before data analysis in data analysis. In order to obtain the reliability and sophistication of statistics as a result of big data analysis, it is necessary to analyze the meaning of each variable and the correlation between the variables. If the data is classified differently from the hypothesis test from the beginning, even if the analysis is performed well, unreliable results will be obtained. In other words, prior to big data analysis, it is necessary to ensure that data is well classified to suit the purpose of analysis. This is a process that must be performed before reaching the result by analyzing the data, and it may be a method of optimal data classification.

• 천문학회보
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• 제46권2호
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• pp.38.1-38.1
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• 2021

Dust polarization depends on the physical and mechanical properties of dust, as well as the properties of local environments. To understand how dust polarization varies with grain mechanical properties and the local environment, in this paper, we model the wavelength-dependence polarization of starlight and polarized dust emission by aligned grains by simultaneously taking into account grain alignment and rotational disruption by radiative torques (RATs). We explore a wide range of the local radiation field and grain mechanical properties characterized by tensile strength. We find that the maximum polarization and the peak wavelength shift to shorter wavelengths as the radiation strength U increases due to the enhanced alignment of small grains. Grain rotational disruption by RATs tends to decrease the optical-near infrared polarization but increases the ultraviolet polarization of starlight due to the conversion of large grains into smaller ones. In particular, we find that the submillimeter (submm) polarization degree at 850㎛(P850) does not increase monotonically with the radiation strength or grain temperature (Td), but it depends on the tensile strength of grain materials. Our physical model of dust polarization can be tested with observations toward star-forming regions or molecular clouds irradiated by a nearby star, which have higher radiation intensity than the average interstellar radiation field. Finally, we compare our predictions of the P850-Td relationship with Planck data and find that the observed decrease of P850 with Td can be explained when grain disruption by RATs is accounted for, suggesting that interstellar grains unlikely to have a compact structure but perhaps a composite one. The variation of the submm polarization with U (or Td)can provide a valuable constraint on the internal structures of cosmic dust