• Title/Summary/Keyword: Science Laboratory

Search Result 15,951, Processing Time 0.044 seconds

Review on the Aims of Laboratory Activities in School Science (학교 과학수업에서 실험의 목적에 대한 고찰)

  • Yang Il-Ho;Cho Hyun-Jun
    • Journal of Korean Elementary Science Education
    • /
    • v.24 no.3
    • /
    • pp.268-280
    • /
    • 2005

  • Teaching with laboratory activities in school science, which are distinctive characteristic, is placed from other disciplines fur teaming almost 200 hundred years ago. A number of science educators have suggested that there are rich benefits in teaming from using laboratory activities. At these time, however, some educators have begun to seriously question the effectiveness and the role of laboratory activities. There are some causes related to obscure and vague aims of laboratory activities. The purposes of this paper is to review aims of laboratory activities presented in the literatures through historical overview, and to obtain implication for school science. There are various aims of laboratory activities by a number of researchers. Overall synthesizing, there are ffur domains of aims of science teaching through laboratory activities, (a) science knowledge has two sub-domains; scientific content knowledge and procedural knowledge, (b) nature of science, (c) science attitude has two sub-domain; scientific attitude and attitude toward science, and (d) ability of scientific inquiry has two sub-domain; manipulative skills and scientific thinking. But, it is necessary to continue the following study in order to obtain the aims of laboratory activities agreed by expert community, and setting up of lists of aims of laboratory activities for students to achieve hierarchies of school science curriculums.

  • PDF

The Inhibitory Effects of Glycyrrhiza uralensis on human Platelet Aggregation and Thrombus Formation

  • Seung Na Ko;Ji Won Son;Gyu Ri Kim;Min Seon Kim;Yea Jin Lee;Seung Ju Kim;Ji Hyeon Shin;Da In Jo;Woo Young Bok;Hye Gyo Oh;Hyuk-Woo Kwon
    • Biomedical Science Letters
    • /
    • v.29 no.4
    • /
    • pp.242-248
    • /
    • 2023

  • Platelets are activated at the sites of vascular injury by a number of molecules, including adenosine diphosphate, collagen and thrombin. The full platelet aggregation is absolutely essential for the normal hemostasis. Glycyrrhiza glabra is a well-known medicinal herb that grows in various parts of the world and is known to have various effects such as antioxidant, anti-inflammatory, anti-atherogenic, anti-osteoporotic and skin-whitening. However, the platelet inhibitory effect of Glycyrrhiza glabra extract (GGE) has not been identified. In this study, we investigated if GGE inhibited platelet aggregation. We observed that GGE inhibited collagen-induced platelet aggregation, Ca2+ mobilization, and thromboxane A2 generation. In addition, GGE suppressed phosphorylation of phosphatidylinositol-3 kinase (PI3K), Akt and elevated phosphorylation of inositol 1,4,5-trisphosphate receptor (IP3R), vasodilator stimulated phosphoprotein (VASP). Taken together, GGE showed strong antiplatelet effects and may be used to block platelet-mediated cardiovascular diseases.

  • https://doi.org/10.15616/BSL.2023.29.4.242 인용 PDF