• 대한두경부종양학회지
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• 제39권1호
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• pp.37-40
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• 2023

Schwannoma is a slow growing benign tumor that can occur anywhere in our body. About 25~45% cases of schwannomas occur in the head and neck, but intra-thyroidal schwannomas are very rare, and mostly are diagnosed by post-thyroidectomy pathologic study. In this article, we present a case of intra-thyroidal schwannoma diagnosed preoperatively with core needle biopsy. The patient underwent enucleation of the thyroid tumor, and the pathology of the tumor was confirmed as schwannoma. Few cases of intra-thyroidal schwannomas have been reported in the literature, but none of them have been diagnosed through core needle biopsy preoperatively. Preoperative diagnosis of intra-thyroidal schwannoma can be helpful when determining appropriate surgical extent and avoid unnecessary thyroidectomy.

• 대한골관절종양학회지
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• 제20권2호
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• pp.60-65
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• 2014

목적: 연부조직 종양 중 지방종과 신경초종(Schwannoma)은 자기공명영상촬영(MRI)만으로 충분한 진단적 가치를 가지는 종양이다. 하지만 신경초종의 경우 종양의 특성상 MRI에서 다양한 형태의 영상으로 나타날 수 있고, 신경주변에 생긴 다른 종양이 MRI상 신경초종으로 오인되는 경우도 드물지 않게 있다. 따라서 MRI상 신경초종으로 의심되는 환자를 대상으로 하여 MRI에서 신경초종을 감별할 수 있는 인자들을 찾아보고자 하였다. 대상 및 방법: 2002년 1월부터 2013년 5월까지 술 전 자기공명영상촬영(MRI)상 신경초종(schwannoma)이 의심된 환자 104예를 대상으로 하였으며 모든 환자에서 수술적 치료를 통한 조직검사를 시행하여 최종 진단 하였다. 조직 검사 결과 신경초종이 나온 경우를 1군으로 하고, 다른 병변이 나온 경우를 2군으로 나누어서 MRI 상 신경초종을 의심할 수 있는 영상의학적 소견을 비교 분석하였다. 결과: 104예의 조직검사 결과 신경초종으로 진단된 경우는 92예이며, 신경초종 외에 다른 병변으로 진단된 경우는 12예였다. MRI 특이 소견중 target sign은 1군에서는 41예(45%), 2군에서는 없었으며, fascicular sign은 1군에서는 47예(51%), 2군에서는 2예(17%), fat split sign은 1군에서는 44예(48%), 2군에서는 5예(42%), nerve entering and exiting sign은 1군에서는 28예(30%), 2군에서는 1예(9%)가 나타났다. 위 네가지 소견 모두 나타나지 않은 경우는 1군에서 8예(9%), 2군에서 6예(50%) 였다. 종양이 신경 주행 경로에 있는 경우는 1군에서 52예(57%), 2군에서 5예(42%)였다. Chi-squared test를 이용한 통계학적 분석에서, 위의 네가지 소견 중 target sign이 신경초종의 진단과 유의한 관계를 보였다(p<0.05). 결론: 신경초종 진단에 MRI가 중추적인 역할을 하고 있지만, 신경초종이 지닌 여러가지 특성으로 인해 MRI상 신경초종으로 의심된 경우라고 하더라도 최종적으로는 다른 종양으로 확진 된 경우가 드물지 않게 있다. 그러므로 MRI상 과녁징후가 보이지 않는 신경초종의 경우에는 다른 종양의 가능성도 염두에 두고 접근을 해야 할 것으로 보인다.

• Investigative Magnetic Resonance Imaging
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• 제13권2호
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• pp.207-212
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• 2009

척수내 신경집종은 드문 척수내 종양으로 추적 자기공명영상 소견에서 악화된 증례는 보고된 바가 없다. 우리는 신경섬유종이 없는 환자에서 생긴 흉추 척수내 신경집종의 초기 영상소견과 추적 자기공명영상을 보고하고자 한다. 추적 자기공명영상에서 척수내 종양의 크기가 커지고, 동반된 부종의 범위가 증가하여 악성처럼 보여도, 척수내 종양의 감별진단에 척수내 신경집종을 반드시 포함하여야 하겠다.

• Journal of Korean Neurosurgical Society
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• 제30권8호
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• pp.1028-1032
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• 2001

The report of massive intratumoral hemorrhage from vestibular schwannoma is rare. A 66-year-old female who had suffered from disturbance of hearing for one year developed severe headache and dizziness. Brain MRI showed crescent shaped mass in the left cerebellopontine angle. A left suboccipital approach revealed an $3{\times}3cm$-sized encapsulated mass. The tumor was totally extirpated together with clot. Histologically the tumor was schwannoma with massive hemorrhage. Postoperative course was uneventful. The authors report the rare case of vestibular schwannoma presenting with intratumoral hemorrhage with review of possible pathophysiology and associated factor.

• Journal of Yeungnam Medical Science
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• 제33권1호
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• pp.21-24
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• 2016

Esophageal schwannoma is a very rare submucosal tumor. We report successful management of esophageal schwannoma in a 41-year-old man who complained of progressively worsening dysphagia. A huge submucosal tumor was found via endoscopy and a chest computed tomography scan. Esophagectomy was performed with no post-operative complications. Post-operative immunohistochemistry staining showed a positive result for S-100 and negative results for c-kit and CD34. The post-operative mild dysphagia persisted, and the follow-up endoscopic findings revealed anastomosis site stenosis. Approximately 2 months later, we performed endoscopic balloon dilatation. We report herein a case of esophageal schwannoma with reviews.

• Journal of Korean Neurosurgical Society
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• 제43권3호
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• pp.135-138
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• 2008

Objective: This study is to report our experience of 40 cases of spinal schwannoma. Methods: From 1995 to 2006, medical records were retrospectively reviewed in 40 cases of spinal schwannoma. Results: We treated 40 spinal schwannomas in 38 (22 male and 16 female) patients. The mean age was 50.2. Four cases were sited in the cervical spine, 11 cases in the thoracic spine, and 25 cases in the lumbar spine. Two patients showed recurrences. Thirty-eight cases were intradural-extramedullary type and 2 cases were extradural. Two cases (5%) including 1 recurred case had no postoperative motor improvement. Ninety-five percents of patients improved on postoperative motor grade. Conclusion: Spinal schwannoma is mostly benign and extramedullary tumor. There were 2 recurred cases (5%) that had history of previous subtotal removal at first operation and had shown worse prognosis compared with the cases without recurrence. To reduce the recurrence of spinal schannoma, total excision of tumor mass should be done.

• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2003년도 추계학술대회초록집
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• pp.8-8
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• 2003

Schwannoma is a neoplasm of the Schwann cells of the neural sheath [1]. Malignant schwannoma is most commonly seen in the subcutis of the flank or neck area near the salivary glands [2]. It also occurs in the thoracic and abdominal cavities, spinal cord, cranial cavity, the heart, etc. Here, we incidentally found a good case of malignant schwannoma in the subcutis of the lumbar and lumbosacral region in male F344 rat during the carcinogenicity study with diisodecyl phthalate (DIDP). Therefore, we tried to report this case as a good reference of malignant schwannoma. (omitted)

• Journal of Korean Neurosurgical Society
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• 제30권9호
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• pp.1127-1129
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• 2001

The vast majority of schwannomas occur on cranial nerves, and rarely in the retroperitoneum. Solitary schwannoma in the psoas muscle is extremely rare. The authors present a case of retroperitoneal neoplasm in the psoas muscle identified as schwannoma which is not associated with von Recklinghausen's disease. A 68 years old female patient was admitted because of low back pain and weakness at the left leg. CT and MRI revealed a large cystic mass with well-defined margin and multiple internal septation within the left psoas muscle. The tumor was totally extirpated and histologically confirmed as a schwannoma.

• 대한두경부종양학회지
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• 제24권2호
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• pp.200-202
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• 2008

Schwannoma is a benign soft tissue tumor arising from the schwann cells of the nerve sheath. Although 25 to 45% of schwannomas arise in the head and neck region, larynx is one of the rarest sites of involvement. Recently, we experienced a case of a laryngeal schwannoma causing voice change in a 53-years-old woman. Laryngeal schwannoma is located right false vocal fold with bulging, which was completely removed by microlaryngeal surgical excision. We report a rare case with a review of literature.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제34권6호
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• pp.480-483
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• 2012

Schwannoma is a benign, slow-growing, tumor of the peripheral nerves without specific symptoms, so that early diagnosis may be difficult. Though approximately 25~40% of all schwannomas occur extracranially in the head and neck region, only 1% of schwannomas are reported in the oral cavity. An 18-years-old female patient visited our clinic with a mass on the middle-right-dorsal surface of the tongue slowly growing for 1.5 years. The patient underwent the surgical removal of the neoplasia under general anesthesia. The mass was well capsulated and a cleavage plane was easily found. There was no recidivation during the course of a one-year follow-up. The treatment for schwannoma is surgical excision of the lesion and recurrence after excision of schwannoma is rare. The final diagnosis is made after a histological examination. Differential diagnoses must be made in relation to malignant tumors and in relation to numerous benign neoformations based on epithelial and connective tissues.