• 여성건강간호학회지
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• 제22권1호
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• pp.11-20
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• 2016

Purpose: Today, an increasing number of divorce is shifting family forms and gender role practices. The purpose of this qualitative study was to understand life's experiences of middle-aged divorced women with higher education and profession lives in Korea. Methods: For this study, 6 middle-aged divorced women with similar backgrounds were recruited from December 2013 to June 2014, using in-depth individual interviews. Data analysis was performed using Giorgi's phenomenological methodology. Results: Individual interviews revealed the following 15 meaning of themes and 5 themes. 1) A woman considering herself to be ashamed that she has not lived an ordinary life. 2) The destiny of a woman not having a fortune. 3) An exhilarated mood like a teenage girl's 4) Suppressing an instinctive desire of sex. 5) Being a mother as a woman head of household. Conclusion: This study provides deep understanding of middle-aged divorced women with higher levels of education and professional lives of women who experienced difficult times and overcame their problems. Based on the results of this study, nursing strategies for enhancing quality of life need to be created and implemented for all professional women by Korean community networking gradually.

• Biomolecules & Therapeutics
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• 제29권2호
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• pp.144-153
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• 2021

Astrocytes play various important roles such as maintaining brain homeostasis, supporting neurons, and secreting inflammatory mediators to protect the brain cells. In aged subjects, astrocytes show diversely changed phenotypes and dysfunctions. But, the study of aged astrocytes or astrocytes from aged subjects is not yet sufficient to provide a comprehensive understanding of their important processes in the regulation of brain function. In this study, we induced an in vitro aged astrocyte model through late passage cultivation of rat primary cultured astrocytes. Astrocytes were cultured until passage 7 (P7) as late passage astrocytes and compared with passage 1 (P1) astrocytes as early passage astrocytes to confirm the differences in phenotypes and the effects of serial passage. In this study, we confirmed the morphological, molecular, and functional changes of late passage astrocytes showing aging phenotypes through SA-β-gal staining and measurement of nuclear size. We also observed a reduced expression of inflammatory mediators including IL-1β, IL-6, TNFα, iNOS, and COX2, as well as dysregulation of wound-healing, phagocytosis, and mitochondrial functions such as mitochondrial membrane potential and mitochondrial oxygen consumption rate. Culture-conditioned media obtained from P1 astrocytes promoted neurite outgrowth in immature primary cultures of rat cortices, which is significantly reduced when we treated the immature neurons with the culture media obtained from P7 astrocytes. These results suggest that late passage astrocytes show senescent astrocyte phenotypes with functional defects, which makes it a suitable model for the study of the role of astrocyte senescence on the modulation of normal and pathological brain aging.

• 한국아동복지학
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• 제57호
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• pp.43-82
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• 2017

절대적 소득을 강조하는 물질적 관점으로 사회경제적 지위에 따른 건강 격차를 설명하는 것에 대한 한계가 지적되면서, 비교적 최근 개인의 주관적인 사회경제적 지위와 건강의 관계에 주목한 연구들이 등장하기 시작하였다. 이들 연구는 주로 성인을 대상으로 수행되었으나, 자기평가를 위한 사회적 비교를 활발히 수행하는 학령후기 아동 역시 자신의 사회경제적 지위를 주관적으로 인식할 가능성이 있다. 따라서 본 연구는 아동이 인지한 주관적 사회경제적 지위와 그들의 신체건강과의 관계는 물론, 구체적으로 어떠한 경로를 통해 영향을 미치는지를 심리사회적 관점에 기초하여 살펴보았다. 이를 위해 서울교육건강복지패널 1차 년도(2014) 자료의 초4 아동 394명 및 그들 부모의 응답에 대해 구조방정식분석을 실시하였다. 그 결과, 학령후기 아동의 주관적 사회경제적 지위가 신체건강에 직접적으로 미치는 영향은 유의미하지 않았지만, 심리사회적 관점에 근거한 매개변인인 스트레스, 자기효능감, 및 건강행동을 통해 신체건강에 간접적으로 유의미한 영향을 미침을 확인하였다. 본 연구는 이상의 연구 결과를 바탕으로, 낮은 주관적 사회경제적 지위가 심리사회적 요인에 부정적인 영향이 미침으로써 열악한 신체건강을 초래하는 것을 예방하기 위한 노력을 비롯하여, 아동기 건강증진을 위한 몇 가지 고려사항들을 제안하였다.

• Journal of Ginseng Research
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• 제39권3호
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• pp.250-256
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• 2015

Background: It has been known that ginseng can be applied as a potential nutraceutical for memory impairment; however, experiments with animals of old age are few. Methods: To determine the memory enhancing effect of red ginseng, C57BL/6 mice (21 mo old) were given experimental diet pellets containing 0.12% red ginseng extract (approximately 200 mg/kg/d) for 3 mo. Young and old mice (4 mo and 21 mo old, respectively) were used as the control group. The effect of red ginseng, which ameliorated memory impairment in aged mice, was quantified using Y-maze test, novel objective test, and Morris water maze. Red ginseng ameliorated age-related declines in learning and memory in older mice. In addition, red ginseng's effect on the induction of inducible nitric oxide synthase and proinflammatory cytokines was investigated in the hippocampus of aged mice. Results: Red ginseng treatment suppressed the production of age-processed inducible nitric oxide synthase, cyclooxygenase-2, tumor necrosis factor-${\alpha}$, and interleukin-$1{\beta}$ expressions. Moreover, it was observed that red ginseng had an antioxidative effect on aged mice. The suppressed glutathione level in aged mice was restored with red ginseng treatment. The antioxidative-related enzymes Nrf2 and HO-1 were increased with red ginseng treatment. Conclusion: The results revealed that when red ginseng is administered over long periods, age-related decline of learning and memory is ameliorated through anti-inflammatory activity.

• 한국컴퓨터정보학회논문지
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• 제20권12호
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• pp.137-143
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• 2015

This study is looking to do a new model which overcomes emotional isolation phenomenons of aged people through using an advanced technology in our community approaching an aging society. Senior welfare has been oriented to economically, medically supported welfare model so far. An ageing society going on, even if the scale of welfare cost is bigger and bigger, the level of satisfaction has been decreasing. This is the fact that the expansion of economical support for the aged in emotional alienation is not only a solution for them suffering from emotional isolation phenomenons, which requires a new model for senior welfare. Above all, because the senior welfare oriented to economically, medically supported welfare model can not be continued any more, a new model is required to be sustainable in national finance. This study has a purpose that recovers emotional life of the aged, improves their quality of life, and offers emotional welfare model to be sustainable economically.

• 보건행정학회지
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• 제32권1호
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• pp.29-44
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• 2022

Background: This study was conducted to analyze the impact of having a usual source of care on health behaviors of the middle aged and the elderly, in order to investigate the potential effect of enhancing primary health care in a Korean context. Methods: This study constructed a balanced panel of middle-aged and elderly samples using the Korea Health Panel 2016-2018, and fixed-effect models were used to analyze the data. Results: Among three sets of dependent variables (physical activity, smoking, drinking), statistically significant results were found only in physical activity. Subgroup analysis showed that this effect was not observed in the late elderly (aged 75 and older) and those without chronic diseases. Conclusion: Results of the study implied that enhancing primary health care among middle age and the elderly may have an effect on improving health behaviors. Moving forward to person-centered primary health care from disease-focused primary health care should be considered in high-risk groups such as the middle aged and the elderly with chronic diseases.

• Journal of Korean Neurosurgical Society
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• 제46권5호
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• pp.468-471
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• 2009

Objective : The adolescent presentation of tethered cord syndrome (TCS) is well-recognized, but continues to pose significant diagnostic and management controversies. The authors conducted a retrospective study of clinical outcomes after surgical intervention in 24 school-aged children, adolescents, and young adults with TCS. Methods : All 83 patients with a lipomyelomeningocele (LMMC) underwent untethering surgery for caudal cord tethering between 1987 and 2007. The clinical charts and follow-up data were reviewed. Of these patients, 24 school-aged children, adolescents, and young adults with TCS were studied with respect to the clinical, radiologic, pathologic features, and surgical outcomes. Results : Untethering procedures were performed in 24 patients (age range, 7-25 years) for TCS of various origins (lipoma, lipomyelomeningocele, and tight filum terminale). Specific circumstances involving additional tugging of the already tight conus, and direct trauma to the back precipitated the onset of symptom in 50% of the patients. Diffuse and non-dermatomal leg pain, often referred to the anorectal region, was the most common presenting symptom. Progressive sensorimotor deficits in the lower extremities, as well as bladder and bowel dysfunction, were also common findings, but progressive foot and spinal deformities were noted less frequently. The most common tethered lesions were intradural lipomas, thickened filum and fibrous band adhesions into the placode sac. The surgical outcome was gratifying in relation to pain and motor weakness, but disappointing with respect to resolution of bowel and bladder dysfunction. Of the 24 patients with TCS, pre-operative deficits improved after surgery in 14 (58.3%). remained stable in 8 (33.4%). and worsened in 2 (8.3%). Conclusion : The pathologic lesions of tethered cord syndrome in school-aged children, adolescents, and young adults, are mostly intradural lipomas and tight filum. It is suggested that the degree of cord traction results in neurologic dysfunction in late life due to abnormal tension, aggravated by trauma or repeated tugging of the conus during exercise. Early diagnosis and adequate surgical release might be the keys to the successful outcome in school-aged children, adolescents, and young adults with TCS.

• 보건의료산업학회지
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• 제9권3호
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• pp.187-199
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• 2015

Objectives : This study was conducted to examine social factors associated with problematic drinking among middle- and older-aged men in South Korea. Methods : The data were collected from the baseline survey of the Korean Longitudinal Study of Aging, and the sample consisted of 3,631 men between 45 and 64 years of age and 1,173 men aged 65 or older. This study employed variables identifying various socioeconomic features, social ties, and health-related factors. Logistic regressions were used for the data analysis. Results : Middle-aged men having frequent social relationship with close persons were significantly more likely to be problematic drinkers than those having less frequent social relationships with close persons. Lower education, unemployment, smoking, and depression were associated with problematic drinking only among middle-aged men. Conclusions : We suggest that health professionals develop specific intervention strategies that could lead to more moderate alcohol habits and better health in middle aged Korean men who are actively engaged in social networks. In addition, health professionals need to focus more on the unemployed, lower educated, depressed, and smoking groups for early detection of problematic drinking among middle-aged Korean men.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2004년도 ICCAS
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• pp.87-91
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• 2004

High aged society is rapidly progressing in Japan. The rate of aged person more than 65 years old in the population are estimated 25 % in 2017 and rate of younger population will be decreased at same time. As a result, it is estimated that the human resources that is looking after or supporting for the aged person will be drained in Japan. In the other hand, the society has to provide high quality of life in order to be improved living environment for aged person. To decrease the share of nursing and caring for the aged person, it is required that new supporting systems for aged person have to build up as soon as possible. But it is required that various kind of measurement for posture and movement in activities with a simple and single detector for the aged person. The measurement instrument has to be lightweight and simple structure. The results give us a simple measurement method are classified that the posture of sitting down, lying down in stationary statuses and walking, running and going to up and down on the stairs in moving statuses. The detected data will plane to transmit to wireless mobile system to the host computer.

• The Journal of Korean Physical Therapy
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• 제12권1호
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• pp.141-146
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• 2000

Making aged exercise by their age it unreasonable because there an differences of personal strength of their body. The three elements which control the aged's possibility of exercising effectivencess are the level of the physical strength in the present state, potential capacities of physical strength and age. Examined the physical strength of aged, the pliancy of body is considerably marked decline by and large and fast twitch muscle are withered. The reason why aged often do prime exercise like and infant. Aged are not fit for the speedy exercise and they can give full scope to their ability by continuing the long time exercise. The reason why aged should dwindle is mainly the retardation of recovering their fatigue which is related to the decline of oxygen activity. Anaerobic energy supply reduction makes aged be bad for severe physical exercise. Basal metabolic rate of rely on physical cellular quantity and people exercising has a high basal metabolic rate because of muscular amount. There were no decline of basal metabolic rate fellowing the age and physical non activiti influences on the atrophy of muscle.