• Food Science of Animal Resources
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• v.20 no.4
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• pp.272-281
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• 2000

소시지 제조시 저장기간 연장을 목적으로 첨가되는 potassium sorbate(0.5%, 1.0%)와 nit-rite 감소를 위하여 첨가되는 ascorbic acid의 농도(0.5%, 10%)를 조정하여 오미자 추출물 첨가 소시지의 저장성과 잔존 이질산염 함량을 1$0^{\circ}C$와 3$0^{\circ}C$에서 저장하면서 관찰한 결과 온도에 관계없이 pH, 수분, 부수력, 염도, TBARS, 색차 관능검사 모두 저장기간이 경과함에 따라 낮은 값을 나태었다.(P<0.05),그러나 오미자 첨가 소시지의 잔존 nitrite 함량의변화는 대조구에 비해 낮은 값을 나타내어, 아질산염이 감소된 기능성 소시지의 개발 가능성을 시사하고 있다.그러나 pH의 감소로 인하 보수력의 저하로 조직감이 떨어져 소시지 제조시 첨가 농도를 0.5% 이하로 낮추는 것이 바람직하다고 사료된다.

• Journal of the East Asian Society of Dietary Life
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• v.14 no.5
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• pp.508-512
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• 2004

In other to produce vinegar using Schizandra chinensis Ballon(omija), acetic acid bacteria(AAB) were selected from several conventional vinegars, and total 30 acetic acid bacterial strains were isolated. Among the isolated strains, a strain was selected from medium containing omija juice which showed the highest productivity of acetic acid. The strain was identified as Acetobacter sp. C5-1b. Optimum conditions for acetic acid production of Acetabacter sp. C5-1b were involved with 30t: of fermentation temperature and shaking culture. The acidity of culture medium was reached to 5.3% after 8 days shaking cultivation at 30℃.

• Biomolecules & Therapeutics
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• v.17 no.1
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• pp.47-56
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• 2009

Schizandra chinensis (S. chinensis) exhibits a harmless, 'adaptogen-type' effect leading to improvements in mental performance and learning efficacy in brain. Activated microglia contributes to neuronal injury by releasing neurotoxic products, which make it important to regulate microglial activation to prevent further cytological as well as functional brain damage. However, the effect of S. chinensis on microglial activation has not been examined yet. We have investigated the effects of four compounds (Gomisin A, Gomisin N, Schizandrin and Schizandrol A) from S. chinensis on lipopolysaccharide (LPS)-induced microglial activation. In this study, BV2 microglial cells were activated with LPS and the microglial activation was assessed by up-regulation of activation markers such as nitric oxide (NO), reactive oxygen species (ROS), and matrix metalloproteinase-9 (MMP-9). The results showed that all four compounds significantly reduced the intracellular level of ROS, the release of NO and MMP-9 as well as LPS-induced phosphorylation of ERK1/2. These results strongly suggested that S. chinensis may be useful to modulate inflammation-mediated brain damage by regulating microglial activation.

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2003.04a
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• pp.171-171
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• 2003

• 한국약용작물학회:학술대회논문집
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• 2011.04a
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• pp.332-333
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• 2011

• 한국약용작물학회:학술대회논문집
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• 2010.10a
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• pp.422-423
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• 2010

• 한국약용작물학회:학술대회논문집
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• 2010.10a
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• pp.424-425
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• 2010

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.10a
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• pp.39-39
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• 2018

The Schizandra chinensis (Korean name : omija) is a fruit native to northeast Asia that is cultivated in South Korea and China. Using 1,938 valid patents of 6 group countries, we analyzed the patent trend based on year, countries, applicants, and technology. The technologies are categorized the 10 sub-technologies such as medicine, quasi-drugs, food, feed, cosmetics, cultivation, genome, manufacture, preprocessing, and etc. The technology level and competitiveness are analyzed using patent index such as cites per patent, patent impact index, patent family size and technology strength. In Korea, patent number rapidly increasing and individual technical level is lower than other countries. However, overall technical competitiveness is estimated high due to multiple patents. We suggest that cosmetics and cultivation fields are most likely to be developed in future omiza technology development in Korea. Our study will provides to the information of technical trend to support performing of new projects for omija plant.

• Korean Journal of Medicinal Crop Science
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• v.12 no.2
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• pp.141-148
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• 2004

Two compounds from Gomisin N and Gomisin A were isolated from the fruits of Schizandra chinensis Baillon. The highest extraction yield as 21.36% was observed in the ethanol extract, compared to the yield obtained form the water extract. The extraction yields of the single compounds were measured to be 0.13 and 0.014 Gomisin A and Gomisin N, respectively. Approximately, 90% of the growth of human stomach adenocarcinoma cancer cells was inhibited after adding 1.0 g/l of the ethanol extract. The growth of the human normal lung cell was limited to 24% after adding the ethanol extract. The water extract lowered the specific secretion of $TNF-\acute{a}$ and IL-6 from T cells, $10.3{\times}10^{-4}\;pg/cell\;and\;12.1{\times}10^{-4}\;pg/cell$, respectively, compared to the ethanol extracts. On the other hand, a treatment with the ethanol extract increased the specific secretion of $TNF-\acute{a}$ and IL-6 from human T cells, to $11{\times}10^{-4}\;pg/cell\;and\;14.3{\times}10^{-4}\;pg/cell$, respectively. The crude ethanol extract had the highest effect on the differentiation of human promyelocytic leukemia cells compared to the other extracts and Gomisin A and N. In general, the biological activities of the extracts gradually decreased as the purification process proceeded, which suggests that higher immunostimulatory activities can be maintained by adding the crude extracts of the fruits rather than by adding a single compound.

• The Journal of Korean Medicine
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• v.27 no.4
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• pp.150-155
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• 2006

Object : This study investigated the quality inspection of Schizandra chinensis (Turcz.) Bail distributed in Korea. Methods: To evaluate the quality of these herbal medicines, we carried out TLC pattern analysis, purity, loss on drying, ash, acid-insoluble ash, essential oil contents, dilute ethanol-soluble, water-soluble, ether-soluble extracts and HPLC analysis. Results : As a result, TCL pattern analysis of schizandrin and gomisin A showed Rf=0.64 and 0.74, respectively. To measured content of schizandrin and gomisin A, we quantitatively analyzed using HPLC. The average contents of schizandrin and gomisin A were detected to be 0.60 (${\pm}$0.02)% and 0.12 (${\pm}$0.004)%, respectively. Discussion : As a result of this study, we suggest that the minimum content of schizandrin and gomisin A should be 0.5% and 0.1%, respectively. We could suggest that the minimum of essential oil content should be 0.6 ml.