• 대한화장품학회지
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• 제35권1호
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• pp.41-46
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• 2009

두피의 이상은 탈모, 비듬, 가려움증 등의 두피 질환으로 이어지며, 아직까지 정확한 원인이 규명되지 않은 상태여서 발병하면 치료가 쉽지 않다. 따라서 두피의 생리적인 항상성을 유지해서 두피를 건강한 상태로 유지하는 것이 두피 질환 예방 및 치료에 가장 효과적인 방법이다. 최근 두피 및 모발용 화장품 분야에서는 한의학적으로 효능이 있다고 알려진 약재들을 원료로 사용하려는 시도가 크게 증가하고 있다. 현재까지 화장품 원료로 사용되는 한약재는 대량생산과 규격화 등의 문제로 뜨거운 물에 우려낸 열수추출물을 제형에 혼합하는 형태로 사용하고 있는데, 이 과정에서 고온에 의한 영양소와 효능성분의 파괴는 불가피하다. 따라서 본 연구에서는 한의학적으로 두피 개선 효과가 있다고 알려져 있는 검은콩, 작약, 녹차 잎을 대상으로 성분파괴를 최소화할 수 있는 저온용출법으로 효능 성분을 추출하고, 이 추출물들의 두피 개선 효능을 평가하였다. 실험 결과, 저온용출물들은 열수 추출물보다 평균 2배 이상 높은 항산화력을 보유하였으며, 모낭 및 모발 강화, 두피 보습, 가려움 방지에 효과적임을 확인하였다. 따라서 검은콩, 작약, 녹차잎의 저온용출물은 두피 트러블을 해결하는 효과적인 두피 개선 원료로 활용될 수 있다.

• 한국산학기술학회논문지
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• 제17권12호
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• pp.701-707
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• 2016

본 연구는 지루성 두피염 발생빈도가 높은 것으로 알려진 30~50대 남성 150명을 대상으로 생활 습관과 샴푸 습관이 지루성 두피에 어떠한 영향을 미치는지 알아보고자 하였다. 그 결과 지루성 두피의 주요 원인과 관련이 있다고 알려진 두피 가려움증과 과다 유분, 두피 뾰루지, 두피 붉은 증상에 대하여 샴푸 시기와 잦은 피로감은 모든 증상에서 통계적으로 유의한 영향을 미치는 것으로 조사되었으며(p<0.01), 샴푸 시기, 잦은 피로감, 규칙적인 출 퇴근, 스트레스 민감, 헤어스타일 제품사용 유 무와 같은 생활과 샴푸 습관은 지루성 두피에 영향을 미치는 것으로 확인되었다. 연구 결과를 통해 사무직 군무 종사자들의 생활과 샴푸 습관이 지루성 두피의 발생원인과 통계적으로 유의한 것으로 확인 되었으며, 특히 샴푸 습관과 샴푸의 불완전한 세정 및 모발 건조에 의한 습진이 지루성 두피 발생의 일차적인 원인이 되고, 불규칙적인 출 퇴근과 잦은 피로감, 만성 스트레스가 지루성 두피의 이차적 악화 원인이 되고 있음을 알 수 있었다.

• 한방안이비인후피부과학회지
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• 제26권2호
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• pp.19-29
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• 2013

Objectives : The main purpose of this study is to investigate the efficiency of Gagamchengyoung-tang (Ji$\bar{a}$ji$\check{a}$nq$\bar{i}$ngy$\acute{i}$ng-t$\bar{a}$ng) and examine the febrile tendency in the alopecia patients Methods : Of the patients who have visited Balmers Korean Medicine clinic for alopecia from December first 2012 to December 31st 2012, we enrolled 30 patients and performed heat and cold diagnosis, examine scalp and check hair density. We administrated Gagamchengyoung-tang(Ji$\bar{a}$ji$\check{a}$nq$\bar{i}$ngy$\acute{i}$ng-t$\bar{a}$ng) and acupuncture to all patients. The effect was assessed by scalp condition and hair density Results : The scalp disorder index decreased and hair density increased in alopecia patients with febrile tendency Conclusions : All patients had febrile tendency and Gagamchengyoung-Tang(Ji$\bar{a}$ji$\check{a}$nq$\bar{i}$ngy$\acute{i}$ng-t$\bar{a}$ng) can be effective in the scalp disorder and alopecia.

• 융합정보논문지
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• 제10권5호
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• pp.216-223
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• 2020

본 연구는 신생아 두피 모발의 기저부에서부터 말단부위까지의 외부형태와 모발 가로 직경 대비 모발 표면에 노출된 비늘의 장축 직경 비율을 주사전자현미경으로 관찰하였다. 신생아 모발은 두피에 인접한 부위에서 부터 모발의 끝부분으로 갈수록 완만하게 가늘어지는 것을 확인하였다. 본 연구에서 모발의 두께가 커질수록 노출된 비늘의 장축 직경 비율은 상대적으로 작아지는 것으로 확인되었지만 모발 표면의 노출된 비늘 장축 직경은 모발의 굵기에 관계없이 비슷한 길이로 나타났다. 결론적으로 가는 모발이나 굵은 모발 표면에 노출된 비늘의 장축 직경은 크게 변화하지 않는 것을 확인하였다.

• Applied Microscopy
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• 제27권3호
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• pp.321-332
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• 1997

The dermal papilla is known to playa major role in influencing the form and dynamics of the hair follicle, which probably involves regulatory substances crossing the basal lamina. But little is known about the junctions between the dermal papilla and the surrounding epithelial cells of the hair bulb, or between the connective tissue and the epithelial cells on the outside of the hair follicle. This study was performed to identify the ultrastructural differences between dermoepidermal junction of the skin and connective tissue-epithelial junctions on the outside of the hair follicle and around the dermal papilla of normal anagen hair follicles in the human fetal scalp skin. Electron microscopic findings of dermoepidermal junction in scalp skin showed that basal lamina was very irregular and undulated, and it contained many attachment plaques of hemidesmosomes with sub-basal dense plates, tonofilaments, and anchoring filaments. Also invaginations of plasma membrane of basal keratinocytes were seen. There were clear differences both on the outside of the follicle and around the dermal papilla as compared with similar junction in the skin. In particular, neither hemidesmosomes nor tonofilaments, as seen in dermoepidermal junction, were observed in the dermal papilla. Also attachment plaque, sub-basal dense plate and anchoring filaments were not observed at the junction on the outside of the follicle and the dermal papilla. There were some differences between connective tissue-epithelial junctions on the outside of the hair follicle and around the dermal papilla, ie, smoothness of basal lamina and orthogonal arrangement of collagen fibers were seen in the outside of hair follicle, but not in the dermal papilla. These results indicate that the mechanical connection between the hair follicle and the connective tissue component is much weaker than that between the corresponding components in skin, and it reflects the dynamic processes during the anagen phase of the hair follicle compared to the relatively permanent state of the epidermis.

• 대한화장품학회지
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• 제37권2호
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• pp.161-169
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• 2011

본 연구에서는 발모 소재 개발을 위하여 한방복합처방단의 효소처리에 의한 발모 및 흑모 관련 생리활성을 알아보았다. 효소 처리된 한방 복합 처방단의 자유라디칼 소거활성과 superoxide dismutase 유사활성을 알아보았으며, lipoxygenase 활성 저해효과, $5{\alpha}$-reductase 활성 저해효과 및 멜라닌 생성 촉진효과를 확인하였다. 또한, 인체 피부 일차 자극시험 결과 자극이 없는 저자극으로 나타났다. 이로써, 효소 처리된 한방 복합 처방단은 피부자극 없이 모발제품의 기능성 원료로서 큰 가능성을 가지고 있는 것으로 판단된다.

• 한방안이비인후피부과학회지
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• 제29권4호
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• pp.1-13
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• 2016

Objectives : The purpose of this study is to compare hair and alopecia of Korean Medicine with those of western medicine. Methods : We studied relationships between hair and essense(精), qi(氣), blood(血), five vicera(五臟) and meridians(經絡) through literature review about hair and alopecia. We compared Korean medicine with western medicine on physiology of hair and treatment of alopecia based on the study. Results & Conclusion : 1. Congenital essense(先天之精) is related with genetic factor and acquired essence(後天之精) is connected with nutritional factor. Defending function of Defense qi(衛氣) is related with immune reaction and qi stagnation(氣鬱) is associated with stress reaction. Atrophy of vascular tissues observed in alopecia scalp means deep relationship between blood(血) and alopecia, further deficiency of blood can cause telogen effluvium. 2. Kidney qi(腎氣) is related with inhibiting combination of Androgen receptor and Dihydrotestosterone(DHT) or activating hair growth factior. Pi(脾) is connected with alopecia seborrheica caused by damp-heat(濕熱) and alopecia areata caused by excessive prudence(思慮過度). Heart(心) is associated with atrophy in vascular tissue of scalp and liver(肝) is connected with metabolism. 3. Armpit hair and pubic hair as secondary sex characteristics are realated with Yangming Meridian(陽明經) and beard and hair at crown part where Type II $5{\alpha}$-reductase is activated much are associated with Taiyang Meridian(太陽經). 4. Juglandis Semen pharmacopuncture and Ganoderma lucidum pharmacopucture have better effects on inhibit $5{\alpha}$-reductase than Finasteride. Minoxidil and PRP are similar with promoting blood flow and removing stasis(活血祛瘀). Seven-star needling(七星針) is similar with microneedling. 5. Alopecia can be caused by due to lack of circulation Views we need solution to improve circulation coincide in opinion with Korean Medicine and Western medicine.

• 대한두개안면성형외과학회지
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• 제12권2호
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• pp.116-120
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• 2011

Purpose: Scalp avulsion is a life-threatening injury that may cause trauma to the forehead, eyebrows, and periauricular tissue. It is difficult to treat scalp avulsion as it may lead to severe bleeding. Therefore, emergency scalp replantation surgery is necessary, and we must consider the function, aesthetics, and psychology of the patients. A case of scalp avulsion leading to massive bleeding was encountered by these authors, which led to a failure to achieve the proper operation conditions in an adequate time period. Methods: A 49-year-old female was hospitalized due to having had her head caught in a rotatory machine, causing complete scalp avulsion which included the dorsum of the nose, both eyebrows, and ears. Emergent microsurgical replantation was performed, where a superficial temporal artery and a vein were anastomosed, but the patient's vital signs were too unstable for further operation due to excessive blood loss. Three days after the microanastomosis, venous congestion developed at the replanted scalp, and a medicinal leech was used. Leech therapy resolved the venous congestion. A demarcation then developed between the vitalized scalp tissue and the necrotized area. Debridement was performed 2 times on the necrotized scalp area. Finally, split-thickness skin graft with a dermal acellular matrix ($Matriderm^{(R)}$) was performed on the defective areas, which included the left temporal area, the occipital area, and both eyebrows. Results: The forehead, vertex, right temporal area, and half of the occipital area were successfully replanted, and the hair at the replanted scalp was preserved. As stated above, two-thirds of the scalp survived; the patient could cover the skin graft area with her hair, and could wear a wig. Conclusion: Complete scalp avulsion needs emergent replantation with microsurgical revascularization, but it often leads to serious vital conditions. We report a case with acceptable results, although the microanastomosed vessel was minimal due to the patient's unstable vital signs.

• Archives of Plastic Surgery
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• 제34권3호
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• pp.342-345
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• 2007

Purpose: A common side effect of the scalp reduction is a creation of a 'slot' with the hair growing in the opposite directions away from the scar. Overcoming the unnatural appearance of the slot has been a vexing problem in the scalp reduction surgery. None of the conventional corrective surgical techniques provides a complete and satisfactory aesthetic result. The Frechet flap is a triple transposition flap used for the correction of the slot defect secondary to scalp reduction surgery, seldom needing further scar revision. The Frechet technique provides a solution to the problem of the central slot concealment that is unattainable by other means, such as; Z-plasty and mini-graft. Methods: Authors applied the Frechet technique to Asian patients who had undergone scalp reduction and operated on 4 patients from March, 2000 to January, 2001. Average follow-up period was 13 months. Patients with long scars passing through the temporoparietoccipital zone were excluded. All the undermining was performed in the subgaleal plane, reaching the upper auricular sulcus and stopping just above the nuchal ridge. Results: None of the patients experienced infection, hematoma, nor any permanent hair loss. Transient telogen effluvium at the distal end of flap 2 and 3 was noticeable in one case. Conclusion: In conclusion, the results are aesthetically satisfactory without any significant complications.

• 융합정보논문지
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• 제10권12호
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• pp.208-215
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• 2020

본 연구는 SUKI를 활용하여 두피의 중금속 감소에 대해 미치는 영향에 대해 알아보았다. 연구대상자는 총 26명이었으며 실험군과 대조군 각각 13명이었다. SUKI 도구를 활용한 두피 중금속 배출에 대한 중재를 8주간 주 2회씩 실시하였고, 결과는 다음과 같다. 총 각각 8 종목의 실험군과 대조군의 비교에서 실험군에서 유의한 차이가 있었다. 실험군의 중금속인 Hg, Pb, Al, Cd, As, Ba, Ur, Cs 중에서 6가지 항목의 Hg, Al, Cd, As, Ba, Ur과 같은 중금속들에서 통계적으로 유의한 감소(p<.05)를 보여주었으며, Pb, Cs 는 유의하지 않았다. 그리고 해당 유해중금속 중에서 Al, Ba, Hg가 가장 큰 차이의 감소율을 나타냈다. 따라서 SUKI 도구의 중재가 일부 중금속 배출에 영향을 줄 수 있다는 것을 시사한다(p<.05). 결론적으로 향후 지속적인 연구를 통해 두피의 중금속 배출을 위한 기초자료로 활용될 수 있을 것으로 사료된다.