• Title/Summary/Keyword: Saponins

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Triterpenoidal Saponins from the Leaves of Kalopanax pictum var. chinense

  • Lee, Min-Won;Hahn, Dug-Ryong
    • Archives of Pharmacal Research
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    • v.14 no.2
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    • pp.124-129
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    • 1991

  • One new triterpenoidal bisdesmoside, saponin C (3) were isolated from the leaves of Kalopanax pictum var. chinense along with two known saponins, saponin B (2, sapindoside C) and saponin A (1, sapoindoside B). On the basis of chemical and spectral evidences, the structure of a new triterpenoidal saponin has been elucidated to be 3-O-$\beta$-D-glucopyranosyl (1$\rightarrow$4)$\beta$-D-xylopyranosyl (1$\rightarrow$3)-$\alpha$-L-rhamnopyranosyl (1$\rightarrow$2)-$\alpha$-L-arabino-pyranosyl-23-hydroxyolean-12-en-28-O-$\alpha$-L-rhamnopyrano syl (1$\rightarrow$4)-$\beta$-D-glucopyranosyl (1$\rightarrow$6)-$\beta$-D-glucopyranosyl ester.

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Structure-Activity Relationship of Oleanane Disaccharides isolated from Akebia quinata on Both Cytotoxicity against Cancer Cells and NO inhibition against LPS-induced Macrophage 264.7

  • Jung, Hyun-Ju;Lee, Jung-Ok;Lee, Kyung-Tae;Choi, Jong-Won;Park, Hee-Juhn
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.371.3-372
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    • 2002

  • We have reported cytotoxicities based on several types of sugar linkage in saponins in addition to antitumor and antiinflammatory effects. In order to find further structure-activity relationship on the cytotoxicity of saponins. we intended to isolate oleanane disaccharides Irom the saponin-containing extract of Akebia Quinata (Lardizabalaceae). (omitted)

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