• 제목/요약/키워드: Sam5

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엽산 보충이 호모시스틴 식이에 의해 유발된 고호모시스테인혈증과 간의 S-Adenosylmethionine 대사에 미치는 영향 (Effects of Dietary Folate Supplementation on the Homocystine Diet-Induced Hyperhomocysteinemia and Hepatic S-Adenosylmethionine Metabolism in Rats)

  • 김지명;이화영;장남수
    • Journal of Nutrition and Health
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    • 제36권8호
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    • pp.811-818
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    • 2003
  • We investigated the effects of dietary folate supplementation on plasma homocysteine, vitamin B$_{12}$ and hepatic levels of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in diet-induced hyperhomocysteinemic rats. All animals were fed 0.3% homocysteine diet for 2 weeks, then they were placed either on a 0.3% homocystine or no homocystine with or without 8 mg/kg folate diet for 8 weeks. Homocystine diet induced hyperhomocysteinemia up to 3.5-fold at 10 weeks (28.0 $\pm$ 4.8 $\mu$mol/l vs. 7.9 $\pm$ 0.3 $\mu$mol/l). Dietary folate supplementation caused a significant decrease in plasma homocysteine levels which had been increased by a homocystine-diet. Also, dietary folate supplementation made them return to control levels at 4 wk when the diet was free of homocystine. Plasma folate levels were markedly decreased with homocystine diet with no folate supplementation. Plasma vitamin B$_{12}$ did not differ between groups. Dietary homocystine increased hepatic levels of SAM in folate supplementation group at 10 weeks (p<0.05). Dietary folate supplementation increased hepatic levels of SAM/SAH ratios in homocystine group (p<0.05). In conclusion, dietary folate supplementation can effectively ameliorate the detrimental effects of hyperhomocysteinemia.mia.

유기 트랜지스터를 위한 자가조립단층을 이용한 ITO의 습식 표면개질 (Wet Chemical Surface Modification of ITO by Self Assembled Monolayer for Organic Thin Film Transistor)

  • 지승현;김수호;고재환;박훈;이광훈;윤영수
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2007년도 하계학술대회 논문집 Vol.8
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    • pp.450-450
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    • 2007
  • Indium tin oxide (ITO), which is used as an electrode in organic thin film transistors (OTFT), was modified with a self-assembled monolayer (SAM) by wet chemical surface modification. The surface of the ITO was treated by dipping method in a solution of 2-chloroethane phosphonic acid (2-CEPA) at room temperature. The work function in the ITO which was modified with the SAM in the 2-CEPA had 5.43eV. A surface energy and a transmittance were unchanged in an error range. On this study, therefore, possibility of ohmic contact is showed in the interface between the ITO and the organic semiconductors. These results suggest that the treatment of the ITO with the SAM can greatly enhance the performance of the OTFT.

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Outcome of Children with Severe Acute Malnutrition and Diarrhea: a Cohort Study

  • Bhatnagar, Sakshi;Kumar, Ruchika;Dua, Richa;Basu, Srikanta;Kumar, Praveen
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제22권3호
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    • pp.242-248
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    • 2019
  • Purpose: Severe acute malnutrition (SAM) is an important public health problem which contributes to significant number of under five deaths. Protocol based management significantly decreases risk of deaths in children with medical complications. Methods: Outcome of children aged 2 months-5 years admitted and fulfilling definition of SAM having diarrhea (group A) was compared to children with SAM having medical complications other than diarrhea (group B). Both groups were managed according to standard recommended protocols and monitored and followed up for 12 weeks after discharge. Results: The average weight gain, defaulter rate, primary failure, secondary relapse rate and readmission rate were similar in both groups. Length of stay in group A was three days longer (p-value=0.039). Discharge rate was comparable with overall 68% of children successfully discharged and 50% of children reaching weight/height > -2 standard deviation at follow-up of 12 weeks. Conclusion: The current management protocol is equally effective for managing children with SAM having diarrhea. Good adherence to management protocol of dehydration and timely modification of therapeutic feeds in children with persistent diarrhea results in satisfactory weight gain.

Time uncertainty analysis method for level 2 human reliability analysis of severe accident management strategies

  • Suh, Young A;Kim, Jaewhan;Park, Soo Yong
    • Nuclear Engineering and Technology
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    • 제53권2호
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    • pp.484-497
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    • 2021
  • This paper proposes an extended time uncertainty analysis approach in Level 2 human reliability analysis (HRA) considering severe accident management (SAM) strategies. The method is a time-based model that classifies two time distribution functions-time required and time available-to calculate human failure probabilities from delayed action when implementing SAM strategies. The time required function can be obtained by the combination of four time factors: 1) time for diagnosis and decision by the technical support center (TSC) for a given strategy, 2) time for strategy implementation mainly by the local emergency response organization (ERO), 3) time to verify the effectiveness of the strategy and 4) time for portable equipment transport and installation. This function can vary depending on the given scenario and includes a summation of lognormal distributions and a choice regarding shifting the distribution. The time available function can be obtained via thermal-hydraulic code simulation (MAAP 5.03). The proposed approach was applied to assess SAM strategies that use portable equipment and safety depressurization system valves in a total loss of component cooling water event that could cause reactor vessel failure. The results from the proposed method are more realistic (i.e., not conservative) than other existing methods in evaluating SAM strategies involving the use of portable equipment.

TWO-LAYER MULTI-PARAMETERIZED SCHWARZ ALTERNATING METHOD FOR 3D-PROBLEM

  • KIM, SANG-BAE
    • Journal of applied mathematics & informatics
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    • 제34권5_6호
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    • pp.383-395
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    • 2016
  • The convergence rate of a numerical procedure based on Schwarz Alternating Method (SAM) for solving elliptic boundary value problems depends on the selection of the interface conditions applied on the interior boundaries of the overlapping subdomains. It has been observed that the Robin condition (mixed interface condition), controlled by a parameter, can optimize SAM's convergence rate. In [8], one formulated the twolayer multi-parameterized SAM and determined the optimal values of the multi-parameters to produce the best convergence rate for one-dimensional elliptic boundary value problems. Two-dimensional implementation was presented in [10]. In this paper, we present an implementation for threedimensional problem.

단층/다층 LB 분자막의 내마멸 성능 평가 (Evaluation of Antiwear Performance of Mono/multilayer LB Molecular Films)

  • 안효석;김두인
    • Tribology and Lubricants
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    • 제19권6호
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    • pp.329-334
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    • 2003
  • The antiwear properties of amphiphilic monolayers and composite multilayer on silicon surface were investigated using micro­tribometer and Auger Electron Spectroscopy. Langmuir­Blodgett (LB) monolayers from behenic acid, 2,4­heneicosanedione(HD) and its lopper complex((HD)$_2$Cu) were fabricated on silicon surface and the composite multilayer of 5­bilayer of (HD)$_2$Cu was fabricated on the surface of octadecyltrichlorosilane (OTS) self­assembled monolayer (SAM). We observed that LB monolayers and the composite multilayer exhibited a steady and excellent friction response when compared with the OTS SAM. These LB mono and multilayer also showed much higher wear­resistance than the OTS SAM.

단층/다층 LB 분자막의 트라이볼로지 특성 (Tribological properties of mono/multilayer LB molecular films)

  • 안효석;김두인
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 2003년도 춘계학술대회 논문집
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    • pp.211-214
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    • 2003
  • The tribological properties of amphiphilic monolayers and composite multilayer on silicon surface were investigated using micro-tribometer and Auger Electron Spectroscopy. Langmuir-Blodgett (LB) monolayers from behenic acid. 2.4-heneicosanedione(HD) and its copper complex((HD)$_2$Cu) were fabricated on silicon surface and the composite multilayer of 5-bilayer of (HD)$_2$Cu was fabricated on the surface of octadecyltrichlorsilane (OTS) self-assembled monolayer(SAM). We observed that LB monolayers and the composite multilayer exhibited a steady and excellent friction response when compared with the OTS SAM. These LB mono and multilayer also showed much higher wear-resistance than the OTS SAM.

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퍼지 알고리즘을 이용한 CDMA 복조단 설계 (A Design of CDMA Demodulator Using Fuzzy Algorithm)

  • 정우열
    • 한국컴퓨터정보학회논문지
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    • 제5권2호
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    • pp.121-129
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    • 2000
  • The fuzzy-based SAM algorithm is proposed in this thesis to reduce the idle time. to recover call truncation fast when it is handed off and to last frequency acquisition in the mobile communications. It has additive and adaptive elements. Its weight values are generated not by feedback but by input conversion values. The initial expectation value is defined and forwardㆍbackward searching is executed 4o produce the expectation value of one chip. The fuzzy-based SAM algorithm is applied to the demodulator in CDMA system, and the synchronization time is measured. Synchronization time of PN code is 1.678$\mu\textrm{s}$ by SAM algorithm. It is 993 times faster than time of the conventional systems, 1.667$\mu\textrm{s}$.

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Support Vector Machine and Spectral Angle Mapper Classifications of High Resolution Hyper Spectral Aerial Image

  • Enkhbaatar, Lkhagva;Jayakumar, S.;Heo, Joon
    • 대한원격탐사학회지
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    • 제25권3호
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    • pp.233-242
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    • 2009
  • This paper presents two different types of supervised classifiers such as support vector machine (SVM) and spectral angle mapper (SAM). The Compact Airborne Spectrographic Imager (CASI) high resolution aerial image was classified with the above two classifier. The image was classified into eight land use /land cover classes. Accuracy assessment and Kappa statistics were estimated for SVM and SAM separately. The overall classification accuracy and Kappa statistics value of the SAM were 69.0% and 0.62 respectively, which were higher than those of SVM (62.5%, 0.54).

Electrochemical Properties of Electroactive Monolayers Having $[Os(bpy)_3]^{2+}$ Moieties

  • 방경숙;전일철
    • Bulletin of the Korean Chemical Society
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    • 제22권3호
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    • pp.281-287
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    • 2001
  • Self-assembled monolayers (SAMs) of the alkylthiols with [Os(bpy)3]2+ moiety at the terminal position were prepared on gold electrode surface. Examination of the cyclic voltammograms for the SAM shows that it does not organiz e well unlike alkylthiols, which is attributed to the much larger diameter of [Os(bpy)3]2+ moiety compared with the cross-section of alkyl chains and the distance between the adsorption sites. Electromicrogravimetry study shows that the hydration numbers of the electrolyte were 16 $\pm2$, 11 $\pm1$, 5 $\pm$ 1 and 24 $\pm6$ for ClO4- , PF6-, NO3- , and SO42- , respectively. The binary SAMs of alkylthiols with [Os(bpy)3]2+ terminal-group were prepared by co-adsorption of alkylthiols as spacer molecules, which results in better packing in SAM and accordingly the stability was enhanced.