• Title/Summary/Keyword: Sam

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S-Adenosyl-L-methionine (SAM) Production by Lactic Acid Bacteria Strains Isolated from Different Fermented Kimchi Products

  • Lee, Myung-Ki;Lee, Jong-Kyung;Son, Jeong-A;Kang, Mun-Hui;Koo, Kyung-Hyung;Suh, Joo-Won
    • Food Science and Biotechnology
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    • v.17 no.4
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    • pp.857-860
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    • 2008
  • S-Adenosyl-L-methionine (SAM) is a bioactive material used in the treatment of depression, osteoarthritis, and liver disease. To obtain lactic acid bacteria (LAB) producing high concentrations of SAM, LAB were isolated from commercial kimchi and from prepared kimchi products that contained shrimp jeotgal (fermented salty seafood) or sand lance jeotgal or that were fermented at 5 or $10^{\circ}C$, respectively, when pH was 4.2 to 4.8 and titratable acidity 0.6 to 0.9. Among the 179 LAB strains isolated from the fermented kimchi products, the genus Leuconostoc produced the highest intracellular level of SAM (1.58 mM) and Lactobacillus produced the second highest level (up to 1.47 mM) in the strain culture. This is the first study to quantify SAM in LAB isolated from fermented kimchi prepared by a general kimchi recipe. Ultimately, the selected strains (Leuconostoc mesentroides subsp. mesenteroides/dextranicum KSK417, L. mesentroides subsp. mesenteroides/dextranicum KJM401, and Lactobacillus bifermentans QMW327) could be useful as starters to manufacture fermented foods containing high levels of SAM.

The effects of Sam-chool-gun-bi-tang administration on urine metabolic responses during carbohydrate loading diet to long distance runners (탄수화물 부하식이요법시 삼출건비탕(蔘出健脾湯) 투여가 시합 전·후 장거리 달리기 선수의 뇨중 대사 성분 변화에 미치는 영향)

  • Han, Young-Gyu;Lee, Myeong-Jong
    • The Journal of Dong Guk Oriental Medicine
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    • v.8 no.2
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    • pp.83-96
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    • 2000
  • Objective This experimental study was designed to investigate effects of Sam-chool-gun-bi-tang administration during carbohydrate loading diet to long distance runners on changes of the urine metabolic responses. Materials and Methods All subjects were divided randomly with two groups, Sam-chool-gun- bi-tang administration Group (N=5) and control group (N=5) and attended on domestic marathon race. The urine samples were collected by 15ml conical tube at rest, a day before race, immediately after race, a day after race. These samples were used to analyze for the factors of the change on metabolic responses. At First, the factors of the routine urine test were checked; RBC, WBC, glucose, protein, ketone, bilirubin, urobilirubin. Next, the factors on the changes of the electrolyte metabolism and creatinine were checked; $Na^+ $, $Cl^-$, $K^+$, $Ca^{+ +}$, Creatinine. Results 1. Urine RBC, WBC, glucose, protein, ketone, bilirubin, urobilirubin were all denoted negatively (-). 2. Urine pH response in Sam-chool-gun-bi-tang administration group was shown significant difference between two groups at immediately after race. 3. Urine $Na^+$ response in Sam-chool-gun- bi-tang administration group was shown significant difference between two groups at immediately after race. 4. Urine $K^+$ response in Sam-chool-gun-bi-tang administration group was shown significant difference between two groups at immediately after race and a day after race. 5. Urine $Cl^-$ response in Sam-chool-gun- bi-tang administration group was increased at immediately after race, but was not shown significant difference between two groups. 6. Urine $Ca^{+ +}$ response in Sam-chool-gun-bi-tang administration group was decreased gradually, but was not shown significant difference between two groups. 7. Urine Creatinine response in Control group was decreased significantly at immediately after race, but was not shown significant difference between two groups. Conclusion According to the above results, it was shown that Sam-chool-gun- bi-tang administration had the positive effects on changes of the urine matabolic responses during carbohydrate loading diet to the long distance runners.

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Comparison between TOMS and OMI-derived Tropospheric Ozone (TOMS와 OMI 자료를 이용하여 산출된 대류권 오존 비교 분석)

  • Na, Sun-Mi;Kim, Jae-Hwan
    • Korean Journal of Remote Sensing
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    • v.22 no.4
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    • pp.235-242
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    • 2006
  • This study compared between tropospheric column ozone by applying the SAM method to TOMS and OMI data for northern summer. Tropospheric ozone from the SAM represents a peak over the tropical Atlantic, where it is related with biomass burning. This feature is also seen in the distribution of the model and CO. Additionally, enhancement of the SAM ozone over the Middle East, and South and North America agrees well with the model and CO distribution. However, the SAM results show more ozone than the model results over the northern hemisphere, especially the ocean (e.g. the North Pacific and the North Atlantic). The tropospheric ozone distribution from OMI data shows more ozone than that from TOMS data. This can be caused by different viewing angle, sampling frequency, and a-priori ozone profiles between OMI and TOMS. The correlation between the SAM tropospheric ozone and CO is better than that between the model and CO in the tropics. However, that correlation is reversed in the mid-latitude.

A Study on the Bank's Breach of Contract to keep the Business Secrecy in Transferable Credit Transactions - with a Special Emphasis on the English Case Law, Jackson v. Royal Bank of Scotland - (양도가능신용장거래에서 은행의 영업상 비밀 유지의무위반에 관한 연구 - Jackson v. Royal Bank of Scotland 사건에 대한 영국법원의 판결을 중심으로)

  • Hahn, Jae-Phil
    • Journal of Arbitration Studies
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    • v.16 no.1
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    • pp.277-314
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    • 2006
  • This article aims at analysing the reality of banks' liability resulting from the breach of contract on its part to keep the business secrecy with the supplier in the transferable credit, focusing on a English decision, Jackson v. Royal Bank of Scotland [2005] UKHL 3. In this case, the applicant, 'Econ', had purchased various varieties of pre-packed dog chews in bulk through 'Sam'(lst beneficiary) from 'PPLtd'(2nd beneficiary) in Thailand, using a transferable letter of credit issued by 'RBank'. 'Sam' charged a tremendous amount of mark-up on each transaction and it had not been disclosed to 'Econ', although the identity of 'PPLtd' was revealed to 'Econ' by various documents. However, 'RBank' made an unfortunate error to send an completion statement and other documents including 'PPLtd.'s invoice to 'Econ' instead of to 'Sam'. The effect of the Bank's error was to reveal to 'Econ' the substantial profit that 'Sam' was making on these transactions. CEO of 'Econ' was furious and, as a result, decided to cut 'Sam' out of its importing system and terminated their relationship. 'Sam' sued 'RBank' for damages to recover the loss of profits which could have been possibly made, if the information on the mark-up would not have been exposed to 'Econ'. The House of Lord held that 'RBank' was in breach of its duty of confidence, so 'Sam' was entitled to recover damages on a decreasing scale over 4 years, since there was no specific undertaking from the letter of credit.

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CMP 컨디셔닝 공정에서의 부식방지를 위한 자기조립 단분자막의 적용과 표면특성 평가

  • Jo, Byeong-Jun;Gwon, Tae-Yeong;Venkatesh, R. Prasanna;Kim, Hyeok-Min;Park, Jin-Gu
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2011.05a
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    • pp.33.2-33.2
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    • 2011
  • CMP (Chemical-Mechanical Planarization) 공정이란 화학적 반응과 기계적 힘을 동시에 이용하여 표면을 평탄화하는 공정으로, 반도체 산업에서 회로의 고집적화와 다층구조를 형성하기 위해 CMP 공정이 도입되었으며 반도체 패턴의 미세화와 다층화에 따라 CMP 공정의 중요성은 더욱 강조되고 있다. CMP 공정은 압력, 속도 등의 공정조건과, 화학적 반응을 유도하는 슬러리, 기계적 힘을 위한 패드 등에 의해 복합적으로 영향을 받는다. CMP 공정에서, 폴리우레탄 패드는 많은 기공들을 포함한 그루브(groove)를 형성하고 있어 웨이퍼와 직접적으로 접촉을 하며 공정 중 유입된 슬러리가 효과적으로 연마를 할 수 있도록 도와주는 역할을 한다. 하지만, 공정이 진행 될수록 그루브는 손상이 되어 제 역할을 하지 못하게 된다. 패드 컨디셔닝이란 컨디셔너가 CMP 공정 중에 지속적으로 패드 표면을 연마하여 패드의 손상된 부분을 제거하고 새로운 표면을 노출시켜 패드의 상태를 일정하게 유지시키는 것을 말한다. 한편, 금속박막의 CMP 공정에 사용되는 슬러리는 금속박막과 산화반응을 하기 위하여 산화제를 포함하는데, 산화제는 금속 컨디셔너 표면을 산화시켜 부식을 야기한다. 컨디셔너의 표면부식은 반도체 수율에 직접적인 영향을 줄 수 있는 scratch 등을 발생시킬 뿐만 아니라, 컨디셔너의 수명도 저하시키게 되므로 이를 방지하기 위한 노력이 매우 중요하다. 본 연구에서는 컨디셔너 표면에 연마 잔여물 흡착을 억제하고, 슬러리와 컨디셔너 표면 간에 일어나는 표면부식을 방지하기 위하여 소수성 자기조립 단분자막(SAM: Self-assembled monolayer)을 증착하여 특성을 평가하였다. SAM은 2가지 전구체(FOTS, Dodecanethiol를 사용하여 Vapor SAM 방법으로 증착하였고, 접촉각 측정을 통하여 단분자막의 증착 여부를 평가하였다. 또한 표면부식 특성은 Potentiodynamic polarization와 Electrochemical Impedance Spectroscopy (EIS) 등의 전기화학 분석법을 사용하여 평가되었다. SAM 표면은 정접촉각 측정기(Phoenix 300, SEO)를 사용하여 $90^{\circ}$ 이상의 소수성 접촉각으로써 증착여부를 확인하였다. 또한, 표면에너지 감소로 인하여 슬러리 내의 연마입자 및 연마잔여물 흡착이 감소하는 것을 확인 하였다. Potentiodynamic polarization과 EIS의 결과 분석으로부터 SAM이 증착된 표면의 부식전위와 부식전류밀도가 감소하며, 임피던스 값이 증가하는 것을 확인하였다. 본 연구에서는 컨디셔너 표면에 SAM을 증착 하였고, CMP 공정 중 발생하는 오염물의 흡착을 감소시킴으로써 CMP 연마 효율을 증가하는 동시에 컨디셔너 금속표면의 부식을 방지함으로써 내구성이 증가될 수 있음을 확인 하였다.

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Hepatoprotective Effect of Manual Acupuncture at Sam-hwang Points on $CCl_4$-induced Liver Damage in Rats ($CCl_4$로 유발된 흰쥐의 간손상에 대한 삼황혈(三黃穴) 수기침자극(手技鍼刺戟)의 간기능 보호효과)

  • Lee, Hyun;Hong, Kwon-Eui;Kim, Young-Il;Kim, Tae-Han;Choi, Hak-Joo;Kim, Sun-Jin;Yim, Yun-Kyoung
    • Korean Journal of Acupuncture
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    • v.22 no.1
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    • pp.109-116
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    • 2005
  • Objectives : To investigate the hepatoprotective effect of manual acupuncture at Sam-hwang points on hepatotoxicity in $CCl_4$-intoxicated rats. Methods : Rats were injected intraperitoneally with $CCl_4$(1ml/kg) and treated with manual acupuncture at left Sam-hwang points 3 times a week for 10 weeks. A non-acupoint in left Gluteal area was selected as a sham point. Acupuncture was performed by an experienced acupuncture doctor using tonifying manipulation technique. To estimate the effects on hepatotoxici쇼, body weight and liver weight of rats were measured, and biochemical assays(ALT, AST, ALP, Total cholesterol, etc.) and blood cell analysis were performed. Results : Manual acupuncture with tonifying technique at Sam-hwang points reduced liver weight, ALT, AST, ALP activities and total cholesterol in serum significantly compared with control group. In blood cell analysis, WBC and lymphocytes were reduced but neutrophil was increased by manual acupuncture at Sam-hwang points in rats. Conclusions : Manual acupuncture with tonifying technique at Sam-hwang points has an hepatoprotective effect on $CCl_4$-induced liver damage in rats.

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APPLICATIONS OF INTEGRATED SAFETY ANALYSIS METHODOLOGY TO RELOAD SAFETY EVALUATION

  • Jang, Chan-Su;Um, Kil-Sup
    • Nuclear Engineering and Technology
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    • v.43 no.2
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    • pp.187-194
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    • 2011
  • Korea Nuclear Fuel is developing the X-GEN fuel which shows high performance and robust reliability for the worldwide supply. However, the simplified code systems such as CESEC-III which were developed in 1970s are still used in the current Non-LOCA safety analysis of OPR1000 and APR1400 plants. Therefore, it is essential to secure an advanced safety analysis methodology to make the best use of the merits of X-GEN fuel. To accomplish this purpose, the $\b{i}$ntegrated $\b{s}$afety $\b{a}$nalysis $\b{m}$ethodology (iSAM), is developed by selecting the best-estimate thermal-hydraulic code RETRAN. iSAM possesses remarkable advantages, such as generality, integrity, and designer-friendly features. That is, iSAM can be applied to both OPR1000 and APR1400 plants and uses only one computer code, RETRAN, in the whole scope of the non-LOCA safety analyses. Also the iSAM adopts the unique and automatic initialization and run tool, $\b{a}$utomatic $\b{s}$teady-$\b{s}$tate $\b{i}$nitialization and $\b{s}$afety analysis too l (ASSIST), to enable unhandy designers to use the new design code RETRAN without difficulty. In this paper, a brief overview of the iSAM is given, and the results of applying the iSAM to typical non-LOCA transients being checked during the reload design are reported. The typical non-LOCA transients selected are the single control element assembly withdrawal (SCEAW) accident, the asymmetric steam generator transients (ASGT), the locked rotor (LR) accident, and bank CEA withdrawal (BCEAW) event. Comparison to current licensing results shows a close resemblance; thus, it reveals that the iSAM can be applied to the non-LOCA safety analysis of OPR1000 and APR1400 plants.

Electrochemical Properties and Fabrication of Conjugated System Conducting Oligomer Self-assembled Monolayer (공액구조 전도성 올리고머 자기조립단분자막의 제작 및 전기화학적 특성)

  • Min, Hyun Sik;Lee, Tae Yeon;Oh, Se Young
    • Applied Chemistry for Engineering
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    • v.22 no.5
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    • pp.545-550
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    • 2011
  • We have synthesized a high electrically conductive 4-(2-(4-(acetylthio)phenyl)ethynyl)benzoic acid (APBA) with a conjugated aromatic structure as a bio fix linker, and then fabricated APBA self-assembled monolayer (SAM) with a self-assembly technique. The structure of the prepared APBA SAM was studied and electrochemical properties of APBA SAM immobilized with a ferrocene molecule were investigated. Also, we have examined the molecular orientation and oxidation-reduction redox characteristics of the mixed SAM consisting of APBA and butanethiol (BT) with a X-ray photo electron spectroscopy (XPS) and cyclicvoltammetry, respectively. Electrochemical activity of the mixed SAM was increased with increasing the mixed time. Especially, the maximum redox current was obtained at a mixed time of 36 hrs.

A study on the structure and adaptation intention of the scene appeared in the scenario A Deaf, Sam-ryong(Beong-eoli Samryong) (시나리오 「벙어리 삼룡(이)」의 장면 구조와 각색 의도 연구)

  • Kim, nam-seok
    • (The) Research of the performance art and culture
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    • no.35
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    • pp.339-371
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    • 2017
  • This paper is a study of the film A Deaf, Sam-ryong by Na Un-kyoo released in 1929 at Choseon theater. This study compared the partial scenes of the currently remaining A Deaf, Sam-ryong with related scenarios and original works, after the restructuring of the structure of A Deaf, Sam-ryong and was written for the purpose of reviewing it. The film A Deaf, Sam-ryong is based on Na Dohyang's novel A Deaf, Sam-ryong. However, in the process of adaptation, it was a work that strongly reflected the intention of Na Un-kyoo as a scenario writer. The study of these intentions has to reorganize the remaining scenes at present and rely on research methods to compare them with related scenarios or original works. Even if a situation that makes it difficult to draw clear conclusions is drawn in this research process, we can not but dismiss the method of this research itself if we can not stop the purpose of restoring the loss of Korean cinema. As a result, this study is devised to carry out this study, which had been discontinued due to the lack of work and related data so far.

Bacterial Distributions of Escherichia coli and Bacillus cereus etc. Isolated from Dried Seasoned Marine Products in Garak Fishery Wholesale Market in Seoul, 2009 (그대로 섭취하는 수산가공식품 중 조미건어포류에 대한 주요 식중독균류 분포(2009))

  • Ham, Hee-Jin;Kim, Su-Eon;Ryu, Seung-Hee;Hwang, Young-Ok;Choi, Sung-Min
    • Journal of Food Hygiene and Safety
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    • v.25 no.1
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    • pp.10-15
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    • 2010
  • This study was practiced to survey food-borne bacterial aspects of Escherichia coli and Bacilhus cereus etc. from 210 processed seasoned marine products in Garak fishery wholesale market in Seoul, 2009. Distributions of these bacterial isolates were 28 coliforms, 32 Bacillus spp., 71 Staphylococcus spp., 11 Listeria spp, and 10 Enterococcus spp. in 157 dried squids, 23 dried file fishes, and 20 dried pollacks etc. respectively. Results in 16 kinds of antibiotics susceptibility test by disc diffusion method, special multiple drugs resistance patterns were NOR + LVX + CIP + SAM + VA + S + TE + CF, SAM + C + VA, VA + S + TE, and VA + S in 9 E. coli strains, also, AMC + SAM + CF, SAM + CF, and VA + CF in 21 Bacillus cereus strains respectively. On the basis of the results above, many seasoned dried fishes had multiple drugs resistances, conclusively, we suggest limited guideline and special management on use of antibiotics in floating net cages of fishery farms.