• Imaging Science in Dentistry
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• 제38권1호
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• pp.57-62
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• 2008

The Warthin tumor is a benign neoplasm that occurs mostly in the parotid gland. The tumor frequently occurs in the tail of the parotid gland. A 75-year-old man was referred to Wonkwang dental hospital with a chief complaint of swelling on the right submandibular area. Numerous salivary stones were observed in the right submandibular gland on computed tomography (CT). And the two tumorous lesions were incidentally found in the parotid gland bilaterally. The tumorous lesions showed homogeneous enhancement on the CT and intermediate signal intensity on both T1- and T2-weighted magnetic resonance (MR) images. This tumorous lesions also showed contrast enhancement on fat suppressed T1 weighted MR images. We report common CT and MR features of this case of Warthin tumor in the parotid gland with literature review.

• 한국방사선학회논문지
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• 제9권6호
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• pp.357-362
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• 2015

테크네슘을 이용한 침샘검사의 시간-방사능 곡선에서 다양한 기능매개변수지표를 획득하여 환자 군과 건강한 정상군과의 비교를 통해 유용성을 알아보고자 하였다. 2014년 12월부터 2015년 2월까지 구강 건조증으로 침샘검사를 시행한 환자군 30명과 건강한 정상군 10명을 대상으로 하였다. 99mTc-과산화테크네슘 370 MBq을 정맥으로 주사 후 20분에 비타민C 파우더를 입안에 투여하여 10분 동안 촬영하였다. 분석방법은 귀밑샘과 턱밑샘의 관심영역을 정하여 시간-방사능 곡선을 그린 후 곡선의 각 위치에서 다양한 기능매개변수 지표를 획득하고, 구강 건조증 환자군와 정상군을 비교하였다. 비교 및 측정에 적용된 방법으로는 섭취율(uptake ratio, UR), 최대 방사능 시간(time at maximum counts, Tmax), 최소 방사능 시간(time at minimum counts, Tmin), 최대 축적율(maximum accumulation, MA), 축적 속도(accumulation velocity), 최대 배출율(maximum secretion, MS), 최대 자극 배출율(maximum stimulation secretion, MSS), 배출속도(secretion velocity, SV)를 사용하였다. 환자군과 정상군간의 기능매개변수지표 비교에서 환자군의 최소 방사능 시간(Tmin)을 제외한 모든 지표에서 건강한 정상군이 환자군에 비하여 유의한 차이를 보였고, 시간에 따른 변화량에서도 정상군이 환자군에 비하여 유의한 차이를 보였다. 결론적으로 침샘검사에서 다양한 기능매개변수지표를 이용한 정량분석은 구강 건조증 환자의 침샘 기능을 객관적이고 표준화된 정보로 평가하는데 유용할 것으로 사료된다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제11권1호
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• pp.203-220
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• 1989

Ever since the expression of new tumor-specific antigens was reported during malignant transformation, studies on separation, purification and characterization of these proteins have been so activated recently. Following experiment was performed to observe tumor-specific antigens by implanting DMBA pellet into submaxillary gland of rat for inducing salivary gland tumor. After dividing 280 rats into 2 groups, in control group, sham operation was performed on right submaxillary gland and, in experimental group, DMBA pellet (5mg) was implanted into right submaxillary gland. Then proteins from excised submaxillary gland by killing 10 rats every two weeks for 28 weeks were extracted with 3M KCl, and SDS-PAGE and PAS-staining were carried out for biochemical examination. The obtained results were summarized as follows; 1) At 12th week since implantation of DMBA pellet, tumor mass formation was inspected. And dysplasia at 6th week and invasive epidermoid carcinoma at 10th week were observed by microscope. 2) In control group, the weight ratio of both submaxillary glands had no any change, however, in experimental group, the ratio was increased remarkably. And at 28th week after DMBA implantation, there was more than 15 times of differences in weight between control and experimental group. 3) There was no DMBA remnant after 22nd experimental week. 4) In the SDS-PAGE, high molecular protein bands (more than 100 kd) were appeared much, and new prominent protein bands (66, 48, 41.5, 39, 37, 37.5 kd) were appeared after 4th week since DMBA implantation. However, 38, 27, 22kd protein bands were disappeared. 5) In PAS-staining, high molecular proteins were proteins were all glycoproteins and 37.5kd protein was proved as to be glycoprotein. And 38kd glycoprotein was disappeared after 4th week since DMBA implantation.

• 한국패류학회지
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• 제27권3호
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• pp.253-259
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• 2011

Boring behaviour and drilling mechanism were investigated by visual observations. In this study, of two kinds of holes (the outer and inner holes) which are formed by drilling of boring gastropod Lunatia fortunei (Naticidae), the diameters of the outer holes are broader and larger than those of the inner holes, and their holes look like the crater in shape, as seen in all valves of bivalves bored by Naticidae species. Two kinds of glands (the accessory boring gland and accessory salivary gland) on the foots of boring gastropods have been investigated. Of them, it has been confirmed that only the accessory salivary glands on the foots secreted sulphuric (acidic) components in the mucus (secretion), while the accessory boring glands on the foots did not secrete their components. In this study, we confirmed that L. fortunei possess the accessory boring gland on the foot, as seen in most species in Naticidae. Accoeding to the results of the experiment of the blue litmus paper tests of the mucus (secretions) secreted from the accessory boring gland the color of the blue litmus paper did not turn red in color because chemical components of mucus (secretion) secreted from the accessory boring gland on the foot of L. fortunei (boring gastropod) were not acidic components. It is supposed that the mucus, which is secreted from the accessory boring gland, contained gelatin-like substances or enzymes without acidic components, as already reported in Naticidae species. Therefore, these substances may be involved in softening the surface of the valves of M. veneriformis. Consequently, it is assumed thar L. fortunei bores holes through the shells of molluscs by means of following 3 methods: (1) a softening of the calcareous shells of M. veneriformis with chemical secretions (including gellatin-like substances or enzyme except for acidic components) from the accessory boring glands, (2) mechanical rasping with the radula, (3) a combination of both. In this study, particularly, acidic components, which are involved in softening the surface of the shells, are not associated with the boring mechanism of L. fortunei because chemical acidic components were not detected in the mucus (secretion), as found in Naticidae species.

• 대한기관식도과학회지
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• 제5권2호
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• pp.127-129
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• 1999

Intraductal papilloma is a rare benign tumor reported to be primarily in minor salivary gland. There were few reports in parotid gland. A case of a 5-year-old boy with a palpable mass in the left parotid gland, with a review of the literature pertaining to this unusual case. A supeficial parotidectomy was performed under impression of benign or congenital lesion. Histopathologic diagnosis of intraductal papilloma was made on the surgical specimen. Authors report a intraductal papilloma arising from the parotid gland in childhood.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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• 제61권11호
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• pp.611-614
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• 2018

Lymphoepithelioma-like carcinoma exhibits immunohistochemically similar features to lymphoepithelioma and commonly occurs in the skin, salivary gland, breast, lung, gastrointestinal tract, liver, urinary tract, prostate, vulva and vagina. Lymphoepithelioma-like carcinoma from the thyroid gland is extremely rare. We recently experienced a case of lymphoepithelioma-like carcinoma of thyroid gland in a 28-year-old female, who presented a thyroid nodule that was suspicious of papillary carcinoma. We report this unusual case of lymphoepithelioma-like carcinoma of thyroid gland with a brief review of literature.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제30권6호
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• pp.545-550
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• 2004

Salivary glands, major and minor, are susceptible to a wide variety of pathologic conditions. Excision of the submandibular gland is a surgical procedure often undertaken. The procedure is the treatment of choice for patients with neoplasm of the submandibular gland and those with non-neoplastic submandibular disorders which are not controlled with conservative medical measures. Extirpation of the submandibular gland may also be undertaken for diagnostic purposes. We evaluated 84 patients who had been admitted to the dept. of oral and maxillofacial surgery of Pusan National University Hospital from January, 1989 to December, 2002 and had been performed submandibular gland excision. The results are as follows : 1. The patients undertaken the excision of the submandibular gland showed an age range of 16 to 71 years. The average was 49.1. 2. They consisted of 60 males(71.4%) and 24 females(28.6%), having 2.5 : 1 of genda ratio. 3. The most common symptom was swelling in 41 cases(48.8%), followed by the pain in 23 cases(27.4%). Other symptoms included mass, dysphagia, facial abnormaly and neck dyscinesia. 4. 42 cases(50.0%) showed sialadenitis and sialodochitis associated with salivary calculus. 5. According to the histopathologic study, all cases consisted of 17 neoplasmatic conditions(20.3%) and 67 non-neoplasmatic(79.7%). The neoplasmatic cases included 13 benign tumors and 4 primary malignant tumors. Sialadenitis and sialodochitis associated with or without salivary calculus were most marked, found in 50 cases(59.3%), in the non-neoplasmatic conditions. Pleoomorphic adenoma showed the highest frequency of the benign tumor.

• 대한장애인치과학회지
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• 제12권1호
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• pp.27-30
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• 2016

이번 증례에서는 불편감이나 증상을 스스로 표현하기 어려운 10살의 지적장애를 가진 환자에서 발생한 타석증을 제거하였다. 일반적으로 타석증 환자들은 식사 전이나 식사 도중 심해지는 얼굴 또는 목의 통증으로 치과에 내원하게 된다. 이번 증례에서 본 환자는 인지능력 부족으로 의사소통 능력이 제한되어 증상이나 불편감을 표현하지 않았지만 정기검진 시 치과에서 시행된 검사로 병소를 발견하여 국소마취 하에 절개하여 외과적으로 제거하였다. 장애인 환자에서 구강내의 병소를 파악해서 적절한 시기에 알맞은 치료를 제공하기 위해서 치과의사는 구내외에 걸친 자세하고 전반적인 검사를 시행해야 한다.

• Journal of the Korean Wood Science and Technology
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• 제38권5호
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• pp.421-428
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• 2010

This study investigated on enzyme production in the digestive organs of the native termite (Reticulitermes speratus) in Milyang, Korea. Four types of major cellulases [EG (endo-1,4-${\beta}$-glucanase), BGL (${\beta}$-glucosidase), CBH (cellobiohydrolase) and BXL (${\beta}$-1,4-xylosidase)] were present in the digestive organs of the termite. The strong enzyme activity for BGL was found from the native termite, and also shown that the enzyme was distributed in the salivary gland, foregut, and hindgut. BXL, which breaks down hemicellulose near the amorphous region, was detected mainly from salivary gland, foregut, and midgut. However, CBH was distributed mainly in the hindgut. Meanwhile, EG which degrades cellulose, was found mainly in the hindgut and salivary glands. These facts indicate that celluases production patterns are differ from different sites compare to the same species found in Japan, suggesting that enzyme production in the digestive organs of termites is changed according to their habitats.

• Archives of Plastic Surgery
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• 제35권5호
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• pp.607-610
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• 2008

Purpose: Salivary duct carcinoma(SDC) is uncommon but high grade adenocarcinoma arising in the ductal epithelium of salivary glands. SDC is characterized by distinctive clinical and pathologic features. The most important histologic aspect of this neoplasm is its resemblance to ductal carcinoma of the breast. Clinically SDC is defined by cervical lymph node involvement and distant metastasis with a high rate of recurrence and mortality. We described some of the clinical and pathological features of SDC and the management using case report for our patient. Methods: We present a case of a 40-year-old male with 2-year history of a swelling arising in his left preauricular region. There was a single painless, firm and solid $2{\times}1.5cm$ mass in the left parotid area. Facial nerve function was intact and no cervical lymph node were palpable. In August 2005, we found out $1.7{\times}1.8cm$ sized cystic, nodular lesions that were located in the superficial lobe of left parotid gland through Computed tomography. And then superficial parotidectomy and postoperative radiation therapy were performed in Jan 2007. Results: Pathologically, the specimen were consisted of homogeneous, chondoid to myxoid type of tissues. It was yellow mass that has multiloculated cystic lesions. In postoperative PET(Positiron emission tomography) CT, there was no evidence of uptaking FDG(Fluorodeoxyglucose) into the deep layers of parotid gland and distant metastasis were not seen. Conclusion: Salivary duct carcinoma(SDC) is a rare but high grade adenocarcinoma related to pleomorphic adenocarcinoma. The prognosis of SDC can be different according to the type of tumor such as mucoepidermoid adenocarcinoma, adenoid duct carcinoma and acinar cell carcinoma. So we need to study more carefully for accurate diagnosis in early stage of diagnosis. Although radiotherapy has not yet proven to be a significant factor in overall survival, the combination of parotidectomy and postoperative radiation therapy can lead to more favorable results in treating of SDC.