• Korean Security Journal
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• no.36
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• pp.293-316
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• 2013

Today's high-rise buildings are increasing concern about the safety and evacuation of people related to the fire and threat from outside. Terrorism breaking out in high-rise buildings, a symbol of the national economy results in a number of casualties, economic loss, social fear and damage to national status. That's why high-rise building has also emerged as a target of major terrorist attacks, compared to other types of buildings. We have 54 high-rise buildings in 15 regions over the country. The Ministry of Land, Infrastructure and Transport and Seoul Metropolitan Government have offered the guidelines to prevent terrorist attacks toward high-rise buildings. Since the 9/11 terrorist attacks, the U.S. Federal Emergency Management Agency (FEMA) has developed and taken advantage of the Risk Management Manual Series. According to this manual, pre-assessment is conducted for the prevention of terrorism and particularly in FEMA 455, risk of the surrounding areas, vulnerability, possibility from terrorist attacks are checked. After the check, experts classify the risk of terrorist attacks toward the high-rise buildings and according to the risk classification, architects, security experts and structure engineers can carry out terrorism prevention program for high-rise buildings. The U.K. NaCTSO has also offered the terrorism prevention guidelines. Therefore, the Ministry of Land, Infrastructure and Transport and Seoul Metropolitan Government should make more concrete guidelines for high-rise buildings such as what U.S. FEMA and U.K. NaCTSO implement, including prior evaluation technique for terrorism risk.

• Journal of Korean Society of Steel Construction
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• v.24 no.1
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• pp.101-108
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• 2012

The orthotropic steel deck bridge made by using relatively thin steel plate, and structural members such as transverse and longitudinal ribs, cross beam, etc. in the bridge are fabricated with complex shape by welding. Therefore, the possibility occurring deformation and defects by welding is very high, and stress states in the welded connection parts are very complex. Also, the fatigue cracks in orthotropic steel deck bridge are happening fromthe welded connection parts of secondary member than main member. However, stress evaluation for main members is mainly carried out in the design process of the bridge, detailed stress evaluation and characteristic analysis is not almost reviewed in the structural details which fatigue crack occurred. For the orthotropic steel deck bridge with open ribs which has been serviced for 29 years, in this study, the cause of fatigue crack is investigated and the fatigue safety of the bridge is examined based on fieldmeasurement by the loading test and real traffic condition. Also, structural analyses using gridmodel and detailed analysis model were carried out for the welded connection parts of longitudinal rib and diaphramthat fatigue crack occurred. Additionally, the behavior characteristics due to running vehicles were investigated by using influence area analysis for these structural details, and the occurrence causes of fatigue crack in the target bridge were clarified.

• Korean Journal of Microbiology
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• v.43 no.1
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• pp.23-30
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• 2007

The most rapid Real-time PCR based detection method for Avian influenza A virus (AIV) subtype H5N1 was developed. The target DNA sequence in this study was deduced from H5N1 subtype-specific 387 bp partial gene of hemagglutinin, and was synthesized by using PCR-based gene synthesis on the ground of safety. Real-Time PCR was performed by $GenSpector^{TM}$ using microchip-based, total $1{\mu}l$ of reaction mixture with extremely short time in each steps in PCR. The detection including PCR-amplication and analysis of melting temperature was totally completed within 13 min. The H5N1-specific 189 bp PCR product was correctly amplified until 2.4 molecules of hemagglutinin gene as minimum of templates. This kind of PCR was designated as Quick Real-Time PCR in this study and it could be applied to detect not only AIV H5N1, but also other pathogens using PCR-based detection.

• Economic and Environmental Geology
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• v.50 no.2
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• pp.159-170
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• 2017

The temporal and spatial temperature distribution of the heat storage mortar made of porous feldspar was measured and the thermal properties and electricity consumption were analyzed. For the experiment, two real size chambers (control model and test model) with hot water pipes were constructed. Two large scale models with hot water pipes were constructed. The surface temperature change of the heat storage layer was remotely monitored during the heating and cooling process using infrared thermal imaging camera and temperature sensor. The temperature increased from $20^{\circ}C$ to $30^{\circ}C$ under the heating condition. The temperature of the heat storage layer of the test model was $2.0-3.5^{\circ}C$ higher than the control model and the time to reach the target temperature was shortened. As the distance from the hot water pipe increased, the temperature gap increased from $4.0^{\circ}C$ to $4.8^{\circ}C$. The power consumed until the surface temperature of the heat storage layer reached $30^{\circ}C$ was 2.2 times that of the control model. From the heating experiment, the stepwise temperature and electricity consumption were calculated, and the electricity consumption of the heat storage layer of the test model was reduced by 66%. In the cooling experiment, the surface temperature of the heat storage layer of the test model was maintained $2^{\circ}C$ higher than that of the control model. The heat storage effect of the porous feldspar mortar was confirmed by the temperature experiment. With considering that the time to reheat the heat storage layer is extended, the energy efficiency will be increased.

• The Korean Journal of Pesticide Science
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• v.12 no.4
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• pp.421-428
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• 2008

This study was carried out to elucidate the effects of adjuvants on physicochemical properties and pest control efficacy of pesticide spray solution. Spray droplet sizes of pesticide solution decreased by addition of adjuvants even though its effect varied according to the pesticides. The adhesive effect of pesticides sprayed on target crops by addition of adjuvants varied according to the properties, the application methods, and the spray volume of pesticides. Wash-off of the deposited amount of active ingredients of the solution of tricyclazole WP and fenobucarb EC by simulated rainfall after spraying on rice plants dramatically reduced by adding adjuvants. The retained amount of active ingredients of the pesticides were $1.5{\sim}4.1$ times higher than those without adjuvants when subjected to simulated rainfall 6 hours after spraying. Addition of adjuvants to the propanil EC spray solution enhanced the control efficacy in barnyard grass, Echinocloa crus-galli Beauv. by $8{\sim}30%$, which showed a potential to reduce pesticide use.

• Science of Emotion and Sensibility
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• v.21 no.2
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• pp.15-28
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• 2018

The purpose of this study was to conduct eye-tracking experiments to target large spaces and to analyze the characteristics of pupil gaze by gender. By analyzing the change of pupil size in the eye-tracking experiment, we suggest a template for objective and scientific analyses of gender observation data. Additionally, based on the difference between gender and time to pupil size change, we noted the characteristic of time that gather the visual perception data information and showed that females attend to interesting elements of visual information one to two seconds slower than males. In the initial "$1sec{\rightarrow}2sec$", the pupil size has been increased in leap condition of male and in fixed condition of female. In addition, if condition limits to fixed observation to view the change rates on gender then the pupil size of female was larger than male before 9 seconds, while male's pupil size was larger after 9 seconds. This indicates that females obtain visual information through a relatively larger pupil size during the first 1-8 seconds after stimulus presentation, while males acquire it between 10-15 seconds after input. However, based on the result that the pupil size of female was larger than male on the change of observation time, the pupil size movement on female was energized to watch more interest element after a certain period of time.

• Journal of Korean Society of Environmental Engineers
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• v.30 no.11
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• pp.1075-1086
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• 2008

In order to investigate the applicability and suitability of the industrial by-products to apply mono-layer cover system for non-sanitary landfill sites, 6 different industrial by-products, such as construction waste, bottom ash, gypsum, blast furnace and steel manufacture slags, and stone powder sludge, were evaluated. Various physicochemical and hydrodynamic properties of the industrial byproducts were investigated. The environmental safety was monitored using batch and long-term leaching tests as well. In addition, the flexibility of plants was observed by cultivating them in the industrial by-products. The results for physicochemical properties indicate that most of the materials considered appeared to be suitable for landfill cover. Particularly, the concentration levels of hazardous elements regulated by the Korean Law for Waste Management did not exceed the regulatory limits in all target materials. In addition, the concentrations of regulated elements for the Korean Soil Conservation Law were examined below the regulatory limits in most of materials considered, except for the stone powder sludge. The results of batch and long-term experiments showed bottom ash and construction waste were the most suitable materials for landfill cover among the industrial by-products considered. The results of plant studies indicate that the bottom ash among industrial by-products considered was most effective in developing vegetation on landfill site, showing fast germination and large growth index. At the final covering system made of mixture of soil and bottom ash, the optimum application rate of farmyard manure was observed to be 40-50 Mg/ha.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.23
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• pp.10193-10198
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• 2015

Background: Cancer is a major cause of mortality in developing countries and correct and valid information about the epidemiology of this disease is the first step in the planning of health care in each region. The aim of this study was to determine the relative frequency, mean age and sex ratio of the most 10 common non-skin cancers in the world and Iran, among patients referred to an oncology clinic. Materials and Methods: This descriptive study was conducted in Mashhad, north east of Iran. The data obtained from the records of patients referred to the private oncology center between the years of 1985-2012". According to the latest report of GLOBOCAN study commonest malignancies included were lung, breast, colorectal, prostate, stomach, liver, cervix, esophageal, bladder cancers and Non-Hodgkin lymphoma. Results: A total of 4,606 cases were analyzed. The mean age was $55.5{\pm}13.8years$ (male: $59.5{\pm}13.9$, female: $52.6{\pm}12.9$). Overall, breast cancer (1,264 cases, relative frequency of 27.4%) was the most prevalent cancer; however the mean ages of diagnosis were not significantly different between 5-year time period divisions (p=0.290). The most common cancer in men was esophageal cancer (26.3%).The lowest mean age was related to women diagnosed with breast cancer ($48.5{\pm}11.8$) and men with non-Hodgkins lymphoma ($48.4{\pm}17.8$). There were statistically significant differences between the mean age of men and women with gastric (p=0.003) and esophageal cancers (p<0.001). Male to female sex ratios in our study for bladder, lung and stomach cancers were 6.57, 2.60 and 2.50 respectively. Conclusions: The results showed that breast cancer tends to be found in younger female patients and bladder cancer appears more often in men. Screening in target population in addition to early diagnosis may reduce death and disability.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.1
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• pp.310-315
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• 2017

Although studies evaluating the effects of the blasting vibration on the adjacent structures from various angles have continued, cases of securing the safety of the adjacent buildings and researching the proper blasting method for the field condition by analyzing the vibration waveform of the measuring field while performing the open pit blasting are poor. Therefore, it is necessary to present a remedy for blasting pattern selection through test blasting that is appropriate for field conditions, and is economical and efficient. In this study, open pit blasting work was conducted based on the separation distance applied according to the standard blasting method by test blasting and the vibration regulation standard in the road expansion construction site to measure the blasting vibration value, and the vibration prediction equation by blasting methods was examined using a regression analysis computer program to calculate K, N, and R of the confidence level 95%. By setting the blasting allowed vibration standard of the test blasting target area to 0.3cm/sec, and the charring weight and blasting method by the separation distances according to the blasting vibration estimation equation of the open pit blasting guideline and the blasting vibration estimation equation of the test blasting were compared/analyzed, it was possible to identify the factors that increased the working expenses. In addition, the measurement and analysis of the adjacent structures during open pit blasting and the blasting vibration were performed after selecting the most adjacent structure to the open pit blasting spot to analyze the problems on the test blasting procedure and analysis method in the open pit blasting design/construction guidelines, which appeared in the process of completing open pit blasting construction, and a remedy is presented.

• Journal of Korean Medical classics
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• v.23 no.4
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• pp.63-102
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• 2010

Purpose : To propose various types of clinical research which is feasible for botanical new drug (IND) development processes, and suggest essential steps to development of study protocol for IND. Methods : Literature-based discussions and one research group's experience is given regarding domestic act, regulation, and system. Results : In order to get an approval of IND for botanical drug in Korea there are several types of clinical research to conduct. In quality control steps for standardized medicinal herbs, case reports or case series can be conducted, and for good manufacturing practice(GMP) steps, we can conduct case reports, case series, and retrospective cohort studies. In addition, as long as we gathered good laboratory practice(GLP) data we can conduct up to quasi-experimental studies and clinical trials including investigator initiated trials. In order to conduct these studies development of study protocol is essential. First, we obtain historical evidence including target disease and indication, efficacy, safety, and endpoints by reviewing medical classics. Second, we obtain clinically and statistically important data by conducting non-clinical studies, observation studies, and quasi-experimental studies. Third, we generate research hypotheses and purposes and explore methodologies, endpoints, clinical practice guidelines, cost-effectiveness, and commercial potential. Finally, we develop study protocol with aid of biostatistician or expert in contract research organization. Discussions and conclusions : This study have obvious limitations in that most thoughts, suggestions, and proposes are from one research group's experience. Therefore, we hope to see various types of research in this topic and process from other research group as well.