• Communications for Statistical Applications and Methods
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• 제26권2호
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• pp.163-173
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• 2019

Simon's two-stage designs are frequently used in phase II single-arm trials for efficacy studies. A concern of safety studies is too many patients who experience an adverse event. We show that Simon's two-stage designs for efficacy studies can be similarly used to design a two-stage safety study by modifying some of the design parameters. Given the type I and II error rates and the proportion of adverse events experienced in the first stage cohort, we prescribe a procedure whether to terminate the trial or proceed with a stage 2 trial by recruiting additional patients. We study the relationship between a two-stage design with a safety endpoint and an efficacy endpoint as well as use simulation studies to ascertain their properties. We provide a real-life application and a free R package gen2stage to facilitate direct use of two-stage designs in a safety study.

• Nuclear Engineering and Technology
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• 제51권2호
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• pp.463-478
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• 2019

The most important non-functional requirements for dependability of any Embedded Real-Time Safety Systems are safety, availability and reliability requirements. System architecture plays the primary role in achieving these requirements. Compliance with these non-functional requirements should be ensured early in the development cycle with appropriate considerations during architectural design. In this paper, we present an application of system architecture modeling for quantitative assessment of system dependability. We use probabilistic model checker (PRISM), for dependability analysis of the DTMC model derived from system architecture model. In general, the model checking techniques do not scale well for analyzing large systems, because of prohibitively large state space. It limits the use of model checking techniques in analyzing the systems of practical interest. We propose abstraction based compositional analysis methodology to circumvent this limitation. The effectiveness of the proposed methodology has been demonstrated using the case study involving the dependability analysis of safety system of a large Pressurized Water Reactor (PWR).

• 국제학술발표논문집
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• The 4th International Conference on Construction Engineering and Project Management Organized by the University of New South Wales
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• pp.107-110
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• 2011

The key role in safety management is to identify any possible hazard before it occurs by identifying any possible risk factors which are critical to risk assessment. This planning/assessment process is considered to be tedious and requires a lot of attention due to the following reasons: firstly, falsework (temporary structures) in construction projects is fundamentally important. However, the installation and dismantling of those facilities are one of the high risk activities in the job sites. Secondly, temporary facilities are generally not clearly delineated on the building drawings. It is our strong belief that safety tools have to be simple and convenient enough for the jobsite people to manage them easily and be flexible for any occasions to be occurred at various degrees. In order to develop the safety assessment system, this research utilizes the BIM technology and collects important information by importing data from BIM models and use it in the planning stage.

• Smart Structures and Systems
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• 제25권5호
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• pp.531-541
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• 2020

This paper demonstrates the possibility of evaluating the safety of a building right after an earthquake using consumer-grade surveillance cameras installed in the building. Two cameras are used in each story to extract the time history of interstory drift during the earthquake based on camera calibration, stereo triangulation, and image template matching techniques. The interstory drift of several markers on the rigid floor are used to estimate the motion of the geometric center using the least square approach, then the horizontal interstory drift of any location on the floor can be estimated. A shaking table collapse test of a steel building was conducted to verify the proposed approach. The results indicate that the accuracy of the interstory drift measured by the cameras is high enough to estimate the damage state of the building based on the fragility curve of the interstory drift ratio. On the other hand, the interstory drift measured by an accelerometer tends to underestimate the damage state when residual interstory drift occurs because the low frequency content of the displacement signal is eliminated when high-pass filtering is employed for baseline correction.

• Nuclear Engineering and Technology
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• 제32권4호
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• pp.316-327
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• 2000

The Emergency Core Cooling System in current nuclear power plants typically has a considerable number of complex functions and largely cumbersome operator interfaces. Functions for initiation, switch-over between various phases of operation, interlocks, monitoring, and alarming are usually performed by relays and analog comparator logic which are difficult to maintain and test. To improve problems of an analog based ECC (Emergency Core Cooling) System, the trip computer for ECCS based on Dynamic Safety System (DSS) is implemented. The DSS is a computer based reactor protection system that has fail-safe nature and performs a dynamic self-testing. The most important feature of the DSS is the introduction of test signal that send the system into a tripped state. The test signals are interleaved with the plant signals to produce an output which switches between a tripped and health state. The dynamic operation is a key feature of the failsafe design of the system. In this work, a possible implementation of the DSS using PLC is presented for a CANDU Reactor. ECC System of the CANDU Reactor is selected as the reference system.

• 한국안전학회지
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• 제31권6호
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• pp.58-66
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• 2016

This study aims to estimate the failure probability of concrete gravity dams for their risk analysis under flood situation. To the end, failure modes of concrete gravity dams and their limit state functions are proposed based on numerous review of domestic and international literatures on the dam failure cases and design standards. Three failure modes are proposed: overturning, sliding, and overstress. Based on the failure modes the limit state functions, the failure probability is assessed for a weir section and a non-weir section of a dam in Korea. As water level is rising from operational condition to extreme flood condition, the failure probability is found to be raised up to the warning condition, especially for overturning mode at the non-weir section. The result can be used to reduce the risk of the dam by random environmental variables under possible flood situation.

• 한국안전학회지
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• 제9권4호
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• pp.92-102
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• 1994

NATM as method of tunneling has been applied to construction of domestic subway, roads, rail way, water way etc. Accordingly we have NATM's many drafts and constructional results, but many problems and accidents have occurred under construction of tunnel using NATM for shortage of technical data, poorness of constructional improvement, systemic inconsistency etc. Especially, everyone was shocked at Gupo's train wrecking accident lately. The purpose of this thesis is presentation of means for settling technical problems, by looking into Gupo's train wrecking accident and home records that applying NATM in tunneling failed, to minimize future safety accidents we find that the general problems of home fifteen sites haying occured accidents is badly geological survey, nonconfirmation of base rock's state, formal measuring management, shortage of specialists, systemical discrepancy and that disregarding NATM's rules makes general problems. The results of this study are summarised as follows ; 1. We advise repletion of design standards to practice crosshole test for confirming connected rock base on vertical section of tunnel. 2. We advise to practice pre-boring and pre-grouting for a weak layer difficult in applying NATM. 3. We advise systemic improvements that field servicer can construct tunnel of his own free will considering base rock's state at tunnel. 4. We advise that specialist, who can make a conduct and supervise above mentioned items as well as measuring managements, should be posted at field.

• 한국구조물진단유지관리공학회 논문집
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• 제8권3호
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• pp.225-233
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• 2004

본 연구에서는 응답면기법을 이용하여 격납건물의 내진안전성 평가를 하였다. ABAQUS를 이용하여 하중, 저항과 해석에서의 랜덤변수를 고려한 구조해석을 수행하였고 이로부터 변수의 다항식으로 표현되는 구조물의 응답을 얻었다. 그리고 Level II에 의해 신뢰성해석을 하였다. 한계상태함수로는 콘크리트의 2축응력 상태를 고려하기 위해 Drucker-Prager 파괴기준을 이용하였다. 구조물의 수명, 지진의 연발생율과 조건부 파괴확률을 고려하여 격납건물의 파괴확률을 계산하였다. 또한 응답면기법의 안정적인 결과를 얻기 위해 표본점 선정에 대한 민감도해석을 수행하였다.

• International Journal of Naval Architecture and Ocean Engineering
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• 제5권3호
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• pp.454-467
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• 2013

A practical Ship Inner Shell Optimization Method (SISOM), the purpose of which is to improve the safety of the seagoing transport ship by decreasing the maximum Still Water Bending Moment (SWBM) of the hull girder under all typical loading conditions, is presented in this paper. The objective of SISOM is to make the maximum SWBM minimum, and the section areas of the inner shell are taken as optimization variables. The main requirements of the ship performances, such as cargo hold capacity, propeller and rudder immersion, bridge visibility, damage stability and prevention of pollution etc., are taken as constraints. The penalty function method is used in SISOM to change the above nonlinear constraint problem into an unconstrained one, which is then solved by applying the steepest descent method. After optimization, the optimal section area distribution of the inner shell is obtained, and the shape of inner shell is adjusted according to the optimal section area. SISOM is applied to a product oil tanker and a bulk carrier, and the maximum SWBM of the two ships is significantly decreased by changing the shape of inner shell plate slightly. The two examples prove that SISOM is highly efficient and valuable to engineering practice.

• 대한안전경영과학회지
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• 제14권1호
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• pp.225-233
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• 2012

The research discusses interrelationship of structural and reliability importance measures which used in the probabilistic safety assessment. The most frequently used component importance measures, such as Birnbaum's Importance (BI), Risk Reduction (RR), Risk Reduction Worth (RRW), RA (Risk Achievement), Risk Achievement Worth (RAW), Fussel Vesely (FV) and Critically Importance (CI) can be derived from two structure importance measures that are developed based on the size and the number of Minimal Path Set (MPS) and Minimal Cut Set (MCS). In order to show an effectiveness of importance measures which is developed in this paper, the three representative functional structures, such as series-parallel, k out of n and bridge are used to compare with Birnbaum's Importance measure. In addition, the study presents the implementation examples of Total Productive Maintenance (TPM) metrics and alternating renewal process models with exponential distribution to calculate the availability and unavailability of component facility for improving system performances. System state structure functions in terms of component states can be converted into the system availability (unavailability) functions by substituting the component reliabilities (unavailabilities) for the component states. The applicable examples are presented in order to help the understanding of practitioners.