• Title/Summary/Keyword: Safety Risk Assessment

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A Systematic Review of Placenta Pharmacopuncture for Neuropsychiatric Diseases in Practice (자하거 약침의 신경정신과 임상 응용에 관한 체계적 문헌 고찰)

  • Shin, Haegue;Lee, Jae-Hyok;Kang, Hyung Won
    • Journal of Oriental Neuropsychiatry
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    • v.33 no.2
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    • pp.157-180
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    • 2022
  • Objectives: To perform a systematic review of placenta pharmacopuncture for treating neuropsychiatric diseases, focusing on its efficacy and the safety so that evidence on its clinical use could be obtained, thus contributing to further studies. Methods: Through Korean, English, and Chinese databases (OASIS, Korean TK, KISS, RISS, ScienceON, Pubmed, Cochrane, EMBASE, CINAHL, AMED, CNKI, and Wanfang), combinations of keywords (placenta, pharmacopuncture, etc.) were used to select clinical studies published until January 2021 about placenta pharmacopuncture for neuropsychiatric diseases. Interventions included combined treatments. Study design included cases studies, series, and clinical trials. Cohort studies, literature reviews, in vitro and animal experiments were excluded. The primary outcomes involved measurements of symptoms, Visual Analogue Scale, or questionnaires. Data extracted from databases were imported to Endnote X7 to remove duplicates. The quality of the literature was assessed based on CAse REports Guidelines and Cochrane's Risk of Bias (ROB). Results: Twenty-one studies were selected, including ten case reports, three case series, two one-armed clinical trials, one non-randomized clinical trial, and five randomized clinical trials. There were six studies on sleep disorders, five studies on stroke sequela, two on mood disorders, two on enuresis, two on Guillain-Barré syndrome, two on multiple sclerosis, one on neurocognitive disorder, and one on vertigo. The most frequent combined treatment was acupuncture in both the experimental group (n=10) and the control group (n=3). Acupoints were ST36, SP6, BL23, CV4, GB20, GV20, N-HN54, and so on. All studies reported improvement of symptoms. The quality of case studies was relatively high. Assessment of ROBs resulted in low risks. Conclusions: Placenta pharmacopuncture is effective for neuropsychiatric diseases such as sleep disorders, mood disorders, enuresis, and neurocognitive disorders. Regarding insomnia, several studies have reported significant improvements with placenta pharmacopuncture. There was no adverse event associated with placenta pharmacopuncture.

Nonlinear incremental dynamic analysis and fragility curves of tall steel buildings with buckling restrained braces and tuned mass dampers

  • Verki, Amir Masoumi;Preciado, Adolfo
    • Earthquakes and Structures
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    • v.22 no.2
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    • pp.169-184
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    • 2022
  • The importance of seismicity in developing countries and the strengthening of buildings is a topic of major importance. Therefore, the study of several solutions with the development of new technologies is of great importance to investigate the damage on retrofitted structures by using probabilistic methods. The Federal Emergency Management Agency considers three types of performance levels by considering different scenarios, intensity and duration. The selection and scaling of ground motions mainly depends on the aim of the study. Intensity-based assessments are the most common and compute the response of buildings for a specified seismic intensity. Assessments based on scenarios estimate the response of buildings to different earthquake scenarios. A risk-based assessment is considered as one of the most effective. This research represents a practical method for developing countries where exists many active faults, tall buildings and lack of good implementable approaches. Therefore, to achieve the main goal, two high-rise steel buildings have been modeled and assessed. The contribution of buckling-restrained braces in the elastic design of both buildings is firstly verified. In the nonlinear static range, both buildings presented repairable damage at the central top part and some life safety hinges at the bottom. The nonlinear incremental dynamic analysis was applied by 15 representative/scaled accelerograms to obtain levels of performance and fragility curves. The results shown that by using probabilistic methods, it is possible to estimate the probability of collapse of retrofitted buildings by buckling-restrained braces and tuned mass dampers, which are practical retrofitting options to protect existing structures against earthquakes.

The development of the seismic fragility curves of existing bridges in Indonesia (Case study: DKI Jakarta)

  • Veby Citra Simanjuntak;Iswandi Imran;Muslinang Moestopo;Herlien D. Setio
    • Structural Monitoring and Maintenance
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    • v.10 no.1
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    • pp.87-105
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    • 2023
  • Seismic regulations have been updated from time to time to accommodate an increase in seismic hazards. Comparison of seismic fragility of the existing bridges in Indonesia from different historical periods since the era before 1990 will be the basis for seismic assessment of the bridge stock in Indonesia, most of which are located in earthquake-prone areas, especially those built many years ago with outdated regulations. In this study, seismic fragility curves were developed using incremental non-linear time history analysis and more holistically according to the actual strength of concrete and steel material in Indonesia to determine the uncertainty factor of structural capacity, βc. From the research that has been carried out, based on the current seismic load in SNI 2833:2016/Seismic Map 2017 (7% probability of exceedance in 75 years), the performance level of the bridge in the era before SNI 2833:2016 was Operational-Life Safety whereas the performance level of the bridge designed with SNI 2833:2016 was Elastic - Operational. The potential for more severe damage occurs in greater earthquake intensity. Collapse condition occurs at As = FPGA x PGA value of bridge Era I = 0.93 g; Era II = 1.03 g; Era III = 1.22 g; Era IV = 1.54 g. Furthermore, the fragility analysis was also developed with geometric variations in the same bridge class to see the effect of these variations on the fragility, which is the basis for making bridge risk maps in Indonesia.

Applied Time-Temperature Curve for Safety Evaluation in the Road Tunnel by Fire (도로터널내 화재에 따른 터널구조체의 안정성 평가를 위한 시간-온도곡선의 적용)

  • Won, Jong-Pil;Choi, Min-Jung;Jang, Chang-Il;Lee, Sang-Woo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.29 no.5A
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    • pp.551-555
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    • 2009
  • This study is performed to apply a standard to evaluate fire protection assessment for tunnel structures when a fire breaks out in the road tunnel. Recently, a number of road tunnels have been rapidly increased and fire risk also multiplyed according to extend tunnel length, due to natural features and environmentally-friendly road construction in Korea. But we have not yet been prescribed appropriate time-temperature curve for tunnel fire. Therefore, we presented fire design model and investigated time-temperature curve proposed by a foreign country considering traffic, a kinds of vehicles which are a basis of heat rate. At the end, Hydrocarbon modified curve applied as design fire model by using numerical analysis and presented design fire model and examined the effects of tunnel structures.

Assessment of Apartment Building Construction Workers' Noise Exposure (아파트 건설노동자 소음 노출평가)

  • Taesun Kang
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.33 no.3
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    • pp.308-316
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    • 2023
  • Objectives: The aim of this study is to measure and assess the occupational noise exposure levels among construction workers at apartment building construction sites in South Korea. Methods: Noise exposure assessments were conducted for 139 construction workers across 10 different trades at 53 apartment building construction sites in the northern part of Gyeonggi-do. Assessments were carried out using a noise dosimeter set with a 90 dB criterion, an 80 dB threshold, and a 5 dB exchange rate over a period of more than 6 hours(LMOEL) Results: The mean LMOEL (equivalent continuous noise level over 8 hours) for the 139 dosimeter samples was 87.8 ± 4.3 dBA. The mean noise exposure level for each construction trade, referred to as the trade mean, was also calculated. Significant differences in noise exposure levels were observed between construction trades (ANOVA, p < 0.001). The highest LMOEL values were recorded for concrete chippers (93.2 ± 2.6 dBA), followed by ironworkers (88.4 ± 0.7 dBA), concrete finishers (88.3 ± 2.7 dBA), masonry workers (87.7 ± 1.9 dBA), pile driver operators (85.6 ± 1.7 dBA), concrete carpenters (84.9 ± 2.4 dBA), interior carpenters (83.5 ± 2.1 dBA), and other groups (81.4 ± 2.2 dBA). Conclusions: The findings suggest that nearly all construction workers in this study are at risk of Noise-Induced Hearing Loss (NIHL). Moreover, the study establishes that construction trades can serve as a useful metric for assessing noise exposure levels at apartment construction sites.

Damage identification in a wrought iron railway bridge using the inverse analysis of the static stress response under rail traffic loading

  • Sidali Iglouli;Nadir Boumechra;Karim Hamdaoui
    • Smart Structures and Systems
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    • v.32 no.3
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    • pp.153-166
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    • 2023
  • Health monitoring of civil infrastructures, in particular, old bridges that are still in service, has become more than necessary, given the risk that a possible degradation or failure of these infrastructures can induce on the safety of users in addition to the resulting commercial and economic impact. Bridge integrity assessment has attracted significant research efforts over the past forty years with the aim of developing new damage identification methods applicable to real structures. The bridge of Ouled Mimoun (Tlemcen, Algeria) is one of the oldest railway structure in the country. It was built in 1889. This bridge, which is too low with respect to the level of the road, has suffered multiple shocks from various machines that caused considerable damage to its central part. The present work aims to analyze the stability of this bridge by identifying damages and evaluating the damage rate in different parts of the structure on the basis of a finite element model. The applied method is based on an inverse analysis of the normal stress responses that were calculated from the corresponding recorded strains, during the passage of a real train, by means of a set of strain gauges placed on certain elements of the bridge. The results obtained from the inverse analysis made it possible to successfully locate areas that were really damaged and to estimate the damage rate. These results were also used to detect an excessive rigidity in certain elements due to the presence of plates, which were neglected in the numerical reference model. In the case of the continuous bridge monitoring, this developed method will be a very powerful tool as a smart health monitoring system, allowing engineers to take in time decisions in the event of bridge damage.

Development of Plastic/Gelatin Bilayer Active Packaging Film with Antibacterial and Water-Absorbing Functions for Lamb Preservation

  • Shijing Wang;Weili Rao;Chengli Hou;Raheel Suleman;Zhisheng Zhang;Xiaoyu Chai;Hanxue Tian
    • Food Science of Animal Resources
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    • v.43 no.6
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    • pp.1128-1149
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    • 2023
  • In order to extend the shelf life of refrigerating raw lamb by inhibiting the growth of microorganisms, preventing the oxidation of fat and protein, and absorbing the juice outflow of lamb during storage, an active packaging system based on plastic/gelatin bilayer film with essential oil was developed in this study. Three kinds of petroleum-derived plastic films, oriented polypropylene (OPP), polyethylene terephthalate, and polyethylene, were coated with gelatin to make bilayer films for lamb preservation. The results showed significant improvement in the mechanical properties, oxygen, moisture, and light barriers of the bilayer films compared to the gelatin film. The OPP/gelatin bilayer film was selected for further experiments because of its highest acceptance by panelists. If the amount of juice outflow was less than 350% of the mass of the gelatin layer, it was difficult for the gelatin film to separate from lamb. With the increase in essential oil concentration, the water absorption capacity decreased. The OPP/gelatin bilayer films with 20% mustard or 10% oregano essential oils inhibited the growth of bacteria in lamb and displayed better mechanical properties. Essential oil decreased the brightness and light transmittance of the bilayer films and made the film yellow. In conclusion, our results suggested that the active packaging system based on OPP/gelatin bilayer film was more suitable for raw lamb preservation than single-layer gelatin film or petroleum-derived plastic film, but need further study, including minimizing the amount of essential oil, enhancing the mechanical strength of the gelatin film after water absorption.

Basic concepts, recent advances, and future perspectives in the diagnosis of bovine mastitis

  • Samah Attia Algharib;Ali Sobhy Dawood;Lingli Huang;Aizhen Guo;Gang Zhao;Kaixiang Zhou;Chao Li;Jinhuan Liu;Xin Gao;Wanhe Luo;Shuyu Xie
    • Journal of Veterinary Science
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    • v.25 no.1
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    • pp.18.1-18.27
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    • 2024
  • Mastitis is one of the most widespread infectious diseases that adversely affects the profitability of the dairy industry worldwide. Accurate diagnosis and identification of pathogens early to cull infected animals and minimize the spread of infection in herds is critical for improving treatment effects and dairy farm welfare. The major pathogens causing mastitis and pathogenesis are assessed first. The most recent and advanced strategies for detecting mastitis, including genomics and proteomics approaches, are then evaluated. Finally, the advantages and disadvantages of each technique, potential research directions, and future perspectives are reported. This review provides a theoretical basis to help veterinarians select the most sensitive, specific, and cost-effective approach for detecting bovine mastitis early.

Vest-type System on Machine Learning-based Algorithm to Detect and Predict Falls

  • Ho-Chul Kim;Ho-Seong Hwang;Kwon-Hee Lee;Min-Hee Kim
    • PNF and Movement
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    • v.22 no.1
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    • pp.43-54
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    • 2024
  • Purpose: Falls among persons older than 65 years are a significant concern due to their frequency and severity. This study aimed to develop a vest-type embedded artificial intelligence (AI) system capable of detecting and predicting falls in various scenarios. Methods: In this study, we established and developed a vest-type embedded AI system to judge and predict falls in various directions and situations. To train the AI, we collected data using acceleration and gyroscope values from a six-axis sensor attached to the seventh cervical and the second sacral vertebrae of the user, considering accurate motion analysis of the human body. The model was constructed using a neural network-based AI prediction algorithm to anticipate the direction of falls using the collected pedestrian data. Results: We focused on developing a lightweight and efficient fall prediction model for integration into an embedded AI algorithm system, ensuring real-time network optimization. Our results showed that the accuracy of fall occurrence and direction prediction using the trained fall prediction model was 89.0% and 78.8%, respectively. Furthermore, the fall occurrence and direction prediction accuracy of the model quantized for embedded porting was 87.0 % and 75.5 %, respectively. Conclusion: The developed fall detection and prediction system, designed as a vest-type with an embedded AI algorithm, offers the potential to provide real-time feedback to pedestrians in clinical settings and proactively prepare for accidents.

Effect of the support pressure modes on face stability during shield tunneling

  • Dalong Jin;Yinzun Yang;Rui Zhang;Dajun Yuan;Kang Zhang
    • Geomechanics and Engineering
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    • v.36 no.5
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    • pp.417-426
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    • 2024
  • Shield tunneling method is widely used to build tunnels in complex geological environment. Stability control of tunnel face is the key to the safety of projects. To improve the excavation efficiency or perform equipment maintenance, the excavation chamber sometimes is not fully filled with support medium, which can reduce the load and increase tunneling speed while easily lead to ground collapse. Due to the high risk of the face failure under non-fully support mode, the tunnel face stability should be carefully evaluated. Whether compressive air is required for compensation and how much air pressure should be provided need to be determined accurately. Based on the upper bound theorem of limit analysis, a non-fully support rotational failure model is developed in this study. The failure mechanism of the model is verified by numerical simulation. It shows that increasing the density of supporting medium could significantly improve the stability of tunnel face while the increase of tunnel diameter would be unfavorable for the face stability. The critical support ratio is used to evaluate the face failure under the nonfully support mode, which could be an important index to determine whether the specific unsupported height could be allowed during shield tunneling. To avoid of face failure under the non-fully support mode, several charts are provided for the assessment of compressed air pressure, which could help engineers to determine the required air pressure for face stability.