• Title/Summary/Keyword: SUB1A

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Electroacupuncture and "Duhuojisheng-tang" Administration for Postoperative Treatment in 3 dogs with Traumatic Spinal Cord Injury (외상성 척수 손상에 대한 척추 수술을 한 3마리의 개에서, 술 후 처치로써 전침과 독활기생탕을 적용한 증례)

  • Kim, Min-Su;Kim, Se-Hoon;Cha, Jae-Gwan;Kim, Nam-Soo;Kang, Hyung-Sub
    • Journal of Veterinary Clinics
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    • v.28 no.3
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    • pp.318-322
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    • 2011
  • Three dogs with severe traumatic spinal cord injury (TSCI) due to falling wound were admitted to the Veterinary Medical Center, Chonbuk National University for evaluation of severe pelvic limbs paralysis without deep pain, normal defecation and urination. Based on physical examination, neurological assessment and computed tomogram (CT), the diagnosis was made as subluxation and compressed fracture. All the cases were surgically treated with dorsal laminectomy and a spondylosyndesis using pin and bone cements. For 2 weeks, the dogs didn't show any improvement. Consequently, the dogs were treated with electroacupuncture (EA) and Duhuojisheng-tang (DHJST). All the dogs got back the deep pain and presented wagged tail on 14-35 days after starting EA with DHJST. Especially, two of 3 dogs recovered almost normal ambulation and capacities of urination and defecation. But, one dog failed to regain normal ambulation due to inflammation of operative site which is thought to be caused by the bone cement. From these cases, it was thought that the combination of EA and DHJST mightbe one of the suitable therapies in dogs with no neurological improvement.

Assessment of sediment and total phosphorous loads using SWAT in Oenam watershed, Hwasun, Jeollanam-do (SWAT 모델을 이용한 외남천 유역의 토사 및 총인 유출량 분석)

  • Lee, Taesoo
    • Journal of the Korean association of regional geographers
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    • v.22 no.1
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    • pp.240-250
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    • 2016
  • Monitoring for water quantity and quality was conducted in this study for 2 years (2012~2013) in Oenam Stream which is a tributary of Seomjin River and upstream of Juam Lake. Suspended solid and total phosphorous(TP) were monitored and analyzed, then water quantity and quality as well as their relation with landuses were identified based on the previous study. Flow showed the similar pattern with precipitation but some discrepancies existed due to the distance between weather station(Gwangju) and study area. Watershed was modeled based on observed data using SWAT(Soil and Water Assessment Tool). Model calibration was conducted using data obtained in 2012 and validation was conducted using data in 2013. The coefficient of determination ($R^2$) between observed and modeled showed 0.6644 and 0.5176 for flow and TP, respectively for model calibration period. For validation period, $R^2$ was 0.7529 for flow and 0.7057 for TP, which were higher than calibration period. Hot spots were determined for watershed management by analyzing the amount of sediment and TP outcome from each sub-watershed. TP loading by landuse determined that cropland, of which the area takes only 5% from entire watershed, generated 53.6% of TP and residential and cowshed was responsible for 23.5% of TP loading.

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Effects of Light and Water Soluble Proteins on the Lipid Oxidation of Meat Emulsion Model System during Refrigerated Storage (광 조사 및 차단 조건에서의 고기모형 유화물의 지방산화에 미치는 수용성 단백질의 효과)

  • Park, Hyung-Il;Chung, Myung-Sub;Lee, M.
    • Korean Journal of Food Science and Technology
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    • v.29 no.3
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    • pp.395-399
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    • 1997
  • Meat model emulsions ware prepared with salt-soluble protein and soybean oil. Effects of water-soluble protein (WSP) on the meat model emulsion treated with/without BHT during 8 day storage $5^{\circ}C$ under both dark and light illumination were studied by measuring POV and TBA. An emulsion without BHA and WSP was used as a control. Under light storage, there was no significant difference in peroxide values between the control and the sample treated with BHA except the 2nd day of storage. However, TBA values of the sample treated with BHA were significantly (p<0.05) lower than those of control except the 4th day of storage. TBA and POV of the samples treated with WSP and WSP + BHA were higher than control after 4th day of storage under light. That is, water soluble protein, which was composed mainly of myoglobin, increased lipid oxidation under light storage. The similar trends were also shown in the samples stored under dark. These results suggested that acceleration of lipid oxidation of the meat model emulsions by water soluble protein (WSP) under both light and dark might not be due to the singlet oxygen formation, but due to superoxide anion formed.

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Constructing Forest Information Management System using GIS and Aerial Orthophoto (GIS와 항공정사사진을 이용한 산림정보 관리시스템 구축)

  • Kim, Joon-Bum;Jo, Myung-Hee;Kwon, Tae-Ho;Kim, In-Ho;Jo, Yun-Won;Shin, Dong-Ho
    • Journal of the Korean Association of Geographic Information Studies
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    • v.7 no.2
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    • pp.57-68
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    • 2004
  • Recently in order to more effectively and scientifically process forest official tasks, which have been focused on documents and inventories, they should be applied with the up-to-date spatial information technologies. Especially, the forest resource information management based on GIS(geographic information system) and aerial orthophoto is expected not only to play an important role as DSS(decision support system) for domestic forest conservation policy and forestry development industry but also to service forest resource information toward people such as the owners of a mountain rapidly. In this study, the important forest information such as digital topography map, digital forest type map, digital forest cadastral map, digital aerial photographs and attribute data were first reprocessed and constructed in DBMS(data base management system). In addition, forest officials could analyze and retrieve forest information by using detail sub-application systems such as forest cadastral retrieval, forest land development information management, reserved forest information management and forest resource information retrieval. For this, the user interface is developed by using Visual Basic 6.0 and MapObjects 2.1 of ESRI based on CBD(component based development) technology. The result of developing this system will not only perform constructing economical forest and better environment but also be the foundation of domestic spatial technology for forest resource management.

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The Effect of Kimchi Intake on Free Radical Production and the Inhibition of Oxidation in Young Adults and the Elderly People (김치가 청장년 및 노인의 유리기 생성 및 산화억제에 미치는 영향)

  • 김종현;류재두;무산대학임상병리과
    • Korean Journal of Community Nutrition
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    • v.7 no.2
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    • pp.257-265
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    • 2002
  • This study was performed to investigate the effect of kimchi intake on free radical and oxidative substance production in young adults and the elderly. Daily kimchi intake by people in their twenties (n = 93, 20 to 29 years old) and over sixty-five (n = 143, over 65 years old) in M city were surveyed and blood was drawn to analyze the free radicals in their plasma. The average amount of kimchi intake by the subjects was 115.8 $\pm$ 91.7 g. The amount of kimchi intake of those in their twenties (106.1 $\pm$ 80.6 g) was significantly lower than that of those over sixty-five (125.5 $\pm$ 102.9 g, p < 0.05). Concentrations of total free radicals and OH radicals were 27 and 33% greater respectively, in those over sixty-five than in those in their twenties, indicating that more free radicals were produced by the older group. The concentration of GSH was not signiacantly different in the two groups, but that of GSSG in the over sixty-five age group was 53% greater than in the twenties group, which resulted in a 35% reduction in GSH/GSSG in the elderly group. TBARS concentration in the over sixty-five group was 26% greater than that of the twenties group. In order to see the effect of kimchi intake on free radical production, subjects in same age group were divided into two sub groups-the mean over and the mean under groups-according to the average amount of kimchi intake, which was 115.8 g. The total free radicals, the OH radicals, the GSH, the GSSG, and the GSH/GSSG in the twenties group were not significantly different in the two kimchi intake groups. However, those in the over sixty-five group were significantly different. The concentration of total free radicals and OH radicals of the mean over group were 21 and 26% lower respectively, than those of the mean ova. group (p < 0.05). The GSH and GSH/GSSG of the mean ova. groups were higher by 8 and 12%, respectively. The correlation coefficient between the kimchi intake and the total free radicals was -0.1862 (p < 0.05) and that for GSH/GSSG was 0.1861 (p < 0.05). In conclusion, the production of free radicals and oxidative substances increased with age, and kimchi seemed to retard this phenomena.

Effect of Interlayer on TiN and CrN Thin Films of STS 420 Hybrid-Deposited by AlP and DC Magnetron Sputtering (AIP 와 스퍼터링으로 복합증착된 420 스테인리스강의 TiN과 CrN 박막에 미치는 중간층의 영향)

  • Choi, Woong-Sub;Kim, Hyun-Seung;Park, Burm-Su;Lee, Kyung-Ku;Lee, Doh-Jae;Lee, Kwang-Min
    • Korean Journal of Materials Research
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    • v.17 no.5
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    • pp.256-262
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    • 2007
  • Effects of interlayer and the combination of different coating methods on the mechanical and corrosion behaviors of TiN and CrN coated on 420 stainless steel have been studied. STS 420 specimen were tempered at $300^{\circ}C$ for 1 hr in vacuum furnace. The TiN and CrN thin film with 2 ${\mu}m$ thickness were coated by arc ion plating and DC magnetron sputtering following the formation of interlayer for pure titanium and chromium with 0.2 ${\mu}m$ thickness. The microstructure and surface analysis of the specimen were conducted by using SEM, XRD and roughness tester. Mechanical properties such as hardness and adhesion also were examined. XRD patterns of TiN thin films showed that preferred TiN (111) orientation was observed. The peaks of CrN (111) and $Cr_2N$ (300) were only observed in CrN thin films deposited by arc ion plating. Both TiN and CrN deposited by arc ion plating had the higher adhesion and hardness compared to those formed by magnetron sputtering. The specimen of TiN and CrN on which interlayer deposited by magnetron sputtering and thin film deposited by arc ion plating had the highest adhesion with 22.2 N and 19.2 N. respectively. TiN and CrN samples shown the most noble corrosion potentials when the interlayers were deposited by using magnetron sputtering and the metal nitrides were deposited by using arc ion plating. The most noble corrosion potentials of TiN and CrN were found to be approximately -170 and -70 mV, respectively.

MYLK Polymorphism Associated with Blood Eosinophil Level among Asthmatic Patients in a Korean Population

  • Lee, Soo Ok;Cheong, Hyun Sub;Park, Byung Lae;Bae, Joon Seol;Sim, Won Chul;Chun, Ji-Yong;Isbat, Mohammad;Uh, Soo-Taek;Kim, Yong Hooun;Jang, An-Soo;Park, Choon-Sik;Shin, Hyoung Doo
    • Molecules and Cells
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    • v.27 no.2
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    • pp.175-181
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    • 2009
  • The myosin light chain kinase (MYLK) gene encodes both smooth muscle and nonmuscle cell isoforms. Recently, polymorphisms in MYLK have been reported to be associated with several diseases. To examine the genetic effects of polymorphisms on the risk of asthma and related phenotypes, we scrutinized MYLK by re-sequencing/genotyping and statistical analysis in Korean population (n = 1,015). Seventeen common polymorphisms located in or near exons, having pairwise $r^2$ values less than 0.25, were genotyped. Our statistical analysis did not replicate the associations with the risk of asthma and log-transformed total IgE levels observed among African descendant populations. However, two SNPs in intron 16 (+89872C> G and +92263T> C), which were in tight LD (|D'| = 0.99), revealed significant association with log-transformed blood eosinophil level even after correction multiple testing ($P=0.002/P^{corr}=0.01$ and $P=0.002/P^{corr}=0.01$, respectively). The log-transformed blood eosinophil levels were higher in individuals bearing the minor alleles for +89872C> G and +92263T> C than in those bearing other allele. In additional subgroup analysis, the genetic effects of both SNPs were much more apparent among asthmatic patients and atopic asthma patients. Among atopic asthma patients, the log-transformed blood eosinophil levels were proportionally increased by gene-dose dependent manner of in both +89872C> G and +92263T> C(P = 0.0002 and P = 0.00007, respectively). These findings suggest that MYLK polymorphisms might be among the genetic factors underlying differential increases of blood eosinophil levels among asthmatic patients. Further biological and/or functional studies are needed to confirm our results.

Effects of Swim Training on Tuberculosis infection in the Mouse Model at Different Temperature (온도 차이에 따른 수영훈련이 결핵균 감염정도에 미치는 영향)

  • Kwak Yi-Sub
    • Journal of Life Science
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    • v.15 no.4 s.71
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    • pp.652-656
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    • 2005
  • Tuberculosis is the leading infectious disease in the world. It is urgent to develop new vaccine and treating drugs. Besides vaccines, we want to know the effects of regular swim training on TB infection in the mouse model. This study was designed to examine the effects of regular swim training on lung and spleen TB counts and $INF-\gamma$ activity in the trained mice at different temperature. The trained mice underwent a 10-wk endurance swim training (5 times/wk) in water at $29\~33^{\circ}C$ (WWG) and $21\~23^{\circ}C$(CWG) for 60 min. And they were divided into 3 groups according to the regular swim training (CG; control, WWG; warm water group, and CWG; cold water group). Mice were challenged by aerosol infection with M. tuberculosis H37Rv using an inhalation device (Glas-Col, Terre Haute, Ind.) calibrated to deliver bacteria into lungs. Three weeks after immunization, the mice were challenged. Four weeks after challenge, the mice were sacrificed and the numbers of viable bacteria in lung and spleen were determined by plating serial dilution of whole organ homogenates on nutrient Middlebrook 7H11 agar (Difco, Detroit, MI). Colonies were counted after four weeks incubation at $37^{\circ}C$. All data were expressed as mean, standard deviation by using SPSS package program (win 10.0). The result through the statistical analysis of this data were summarized as follows; In the weight changes, there were significant differences among CG, WWG, and CWG following the swim training at different temperature, and CWG was the lowest. In the change of $INF-\gamma$ following the swim training, there were significant differences (p<.05) among CG, WWG, and CWG after stimulated with media and CFP. In MTB counts, there were significant differences (p<.05) between CG and WWG in the lung. And also there were significant differences (p<.05) among CG, WWG, and CWG. These results suggest that regular swim training suppress Th1 immune response caused by decreased $INF-\gamma$ level in the WWG, Also For the WWG, highly increased level of TB counts appear in the lung and spleen compare to CG.

Relationship of Somatic Cell Score and Udder Type Traits of Holstein Cattle (체세포점수와 홀스타인 유방형질간의 관계)

  • Choi, Tae Jeong;Seo, Kang Seok;Kim, Sidong;Park, Byung Ho;Choi, Je Kwan;Yoon, Ho Paek;Na, Seung Hwan;Son, Sam Kyu;Kwon, Oh Sub;Cho, Kwang Hyun
    • Journal of Animal Science and Technology
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    • v.50 no.3
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    • pp.285-292
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    • 2008
  • Data were taken from the dairy herd improve- ment program from the year 2000, composed of 10,929 first lactation cows consisting of 290,144 test-day records and 37,723 udder type records. The objective of the study was to estimate genetic and phenotypic correlation between fore udder attachment, rear udder height, rear udder width, udder cleft, udder depth, and somatic cell score (SCS) and to calculate heritability of udder depth, front teat length and SCS in Holstein cattle in Korea. The variance component estima- tion using test day model was determined by a derivative-free algorithm-restricted maximum likeli- hood(DF-REML) analysis method. Generally phenotypic correlations were very low between udder traits and lactation SCS which varied from -0.03 to -0.06. Heritability of all type traits and SCS was smaller than 0.12. The results of this study would be applicable to SCS using linear genetic evaluation for future studies.

Effect of Temperatures and Fillers on Yield and Quality of Turmeric (Curcuma longa L.) During Postharvest Seed Rhizome Storage (종근 저장 온도 및 충진제가 강황 수량 및 품질에 미치는 영향)

  • Lim, Jung Dae;Kim, Eun Hye;Yun, Jae Yeon;Park, Hae Il;Shim, Hun Sub;Choi, Ri Na;Yang, Yae Sul;Park, Chung Bum;Ahn, Young Sup;Chung, Ill Min
    • Korean Journal of Medicinal Crop Science
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    • v.21 no.5
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    • pp.334-341
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    • 2013
  • Studies were carried to evaluated the influence of storage method by temperatures and fillers on yield and quality of seed rhizome in turmeric. Seed rhizome was stored at styrofoam box filled with rice hull and sand (3:1) or vermiculite for 30, 60 and 90 days at different temperatures (5, 10 and $15^{\circ}C$. compared to traditional method (rhizome only). Parameters were obtained for weight loss, cold injury, percentage of decayed in stored rhizome during storage periods. Also, the germination, growth pattern and yield from stored rhizome has been investigated. It was confirmed that storage of turmeric in stored with filled with vermiculite helps in prevention of rhizomes from microbial and fungal attack. The storage of rhizomes in styrofoam box without any filler at low temperature below $10^{\circ}C$. is not advocated due to heavy losses weight and decayed in management of postharvest for turmeric rhizome. Germination percentage, growth pattern and yield was maximum for rhizomes stored at styrofoam box filled with vermiculite for 90 days at $15^{\circ}C$. The paper outlines a brief attempt to assess the efficacy of non-chemical methods including optimal storage method (temperature and filler) of control of decay and moisture losses during storage of turmeric.