• Plant Biotechnology Reports
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• v.4 no.2
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• pp.149-155
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• 2010

Expression of the genes for carotenoid bio-synthesis (crt) is dependent on light, but little is known about the underlying mechanism of light sensing and signalling in the cyanobacterium Synechocystis sp. PCC 6803 (hereafter, Synechocystis). In the present study, we investigated the light-induced increase in the transcript levels of Synechocystis crt genes, including phytoene synthase (crtB), phytoene desaturase (crtP), ${\zeta}$-carotene desaturase (crtQ), and ${\beta}$-carotene hydroxylase (crtR), during a darkto-light transition period. During the dark-to-light shift, the increase in the crt transcript levels was not affected by mutations in cyanobacterial photoreceptors, such as phytochromes (cph1, cph2 and cph3) and a cryptochrome-type photoreceptor (ccry), or respiratory electron transport components NDH and Cyd/CtaI. However, treatment with photosynthetic electron transport inhibitors significantly diminished the accumulation of crt gene transcripts. Therefore, the light induction of the Synechocystis crt gene expression is most likely mediated by photosynthetic electron transport rather than by cyanobacterial photoreceptors during the dark-to-light transition.

• Proceedings of the Korean Aquaculture Society Conference
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• 2004.05a
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• pp.513-513
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• 2004

Manila clam, Ruditapes philippinarum, is commercially and ecologically important marine bivalve in Korea and japan. However, clam landings in the two countries have dramatically declined since the 1980-1990's. In the present study, the protozoan parasite, Perkinsus sp., lectin (host's defense-related glycoprotein) and histopathological features were investigated in Manila clams collected from Gomso Bay in Korea and Ariake Bay in japan (one of the largest clam beds in each country) during summer and fall, 2002-2003. DNA sequences of non-transcribe spacer (NTS), internal transcribed space. (ITS) and 5.85 rRNA of Perkinsus sp. were identical to those of P. atlanticus that was reported in Europe and Korea. For diagnosis of Perkinsus, the fluid thioglycollate medium (FTM) and the 2 M NaOH lysis methods were used. Prevalence of the parasite varied from 92.5-98.7% in Gomso Bay and 35.5-37.9% in Ariake Bay. Infection intensity, in terms of the number of Perkinsuscells per gram tissue wet weight, in the clams of Gomso Bay in fall 2002 averaged 1,010,077-470,937 recording approximately100 times higher than that of Ariake Bay, and these were twice higher than those of summer samples in each location. Mean hemagglutination titer of the clams from Gomso Bay was approximately 60-folds higher than that of clams from Ariake Bay in 2002. In histological preparation of the clams from Gomso Bay in 2002, trophozoites of P. atlanticus were in groups and resulted in severe inflammatory response of host clam. Prevalence of the trematod, Cercaria tapes-like in the clams of Gomso Bay and Ariake Bay were 8.8 % and 10.5% respectively. In conclusion, the clams from Gomso Bay showed more severe pathologic symptoms and higher immune response than those of the clams from Ariake Bay.

• Plant Biotechnology Reports
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• v.4 no.4
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• pp.329-334
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• 2010

Multiple sequence alignments showed that the prolines at the 25th, 129th, 153rd, 242nd, 322nd, and 434th amino acids in 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) from Agrobacterium sp. strain CP4 are strongly conserved in various prokaryotic EPSPS proteins. Single point mutations of the conserved prolines to alanine (P25A, P153A, P242A, P322A, and P434A) were introduced in the CP4 EPSPS in order to investigate the importance of the conserved prolines for the enzyme properties. The point mutations caused decreases in substrate binding affinity and catalytic efficiency as well as the glyphosate resistance, in general. Especially, the 25th and 242nd prolines located in the polypeptide hinges connecting top and bottom domains of CP4 EPSPS as well as the 434th proline at the C-terminus of the enzyme turned out to be crucial for the enzyme activity.

• Journal of applied mathematics & informatics
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• v.30 no.3_4
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• pp.571-591
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• 2012

To the best of our knowledge, there is no method, in the literature, to find the fuzzy optimal solution of fully fuzzy shortest path (FFSP) problems i.e., shortest path (SP) problems in which all the parameters are represented by fuzzy numbers. In this paper, a new method is proposed to find the fuzzy optimal solution of FFSP problems. Kumar and Kaur [Methods for solving unbalanced fuzzy transportation problems, Operational Research-An International Journal, 2010 (DOI 10.1007/s 12351-010-0101-3)] proposed a new method with new representation, named as JMD representation, of trapezoidal fuzzy numbers for solving fully fuzzy transportation problems and shown that it is better to solve fully fuzzy transportation problems by using proposed method with JMD representation as compare to proposed method with the existing representation. On the same direction in this paper a new method is proposed to find the solution of FFSP problems and it is shown that it is also better to solve FFSP problems with JMD representation as compare to existing representation. To show the advantages of proposed method with this representation over proposed method with other existing representations. A FFSP problem solved by using proposed method with JMD representation as well as proposed method with other existing representations and the obtained results are compared.

• The Journal of Pediatrics of Korean Medicine
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• v.27 no.4
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• pp.10-16
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• 2013

Objectives The purpose of this study was to investigate the acupuncture therapy about Attention Deficit Hyperactivity Disorder (ADHD) in China. Methods We searched for the studies on ADHD at China National Knowledge Infrastructure (CNKI, http://www.cnki.net) from 2011.1 to 2013.8. Results Selected 12 studies were divided into 7 case reports and 5 control studies. 7 case reports reported significant improvements with acupuncture therapy in ADHD. 5 control studies reported results that the acupuncture therapy groups were similar or better than western medicine treatment groups. Frequently used acupuncture points were EX-HN23 (7 times), GV20 ${\bullet}$ P6 ${\bullet}$ SP6 (6 times), G13 ${\bullet}$ EX-HN1 (5 times). Conclusions There have been reported many ADHD clinical studies in China and these studies can be applied to the clinical practices in Korea.

• Journal of Environmental Health Sciences
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• v.18 no.2
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• pp.26-38
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• 1992

This study was carried out to investigate phytoplankton distributions and water properties at 6 sampling places in Yongsan lake during the period from Jun. 30 to Nov. 17, 1991.Results obtained were as follows: 1. At sampled sites, BOD value ranges from 1.0~14.0 mg/l except Sangmongtan where it was 14.0 mg/l on Nov. 17. 2. T-N and T-P were generally high and the former was 0.26~1.42 mg/l, the latter 0.010~0.158mg/l. 3. At all sampled places, salinity was in the range of 0.04~0.57% but especially downstream of Yongsan lake was high, 0.39~0.57% on Oct. 27. 4. The phytoplankton identification in this survey period showed Cyanophyceae is 11 genera 14 species, Bacillariophyceae 13 genera 22 species, Chlorophyceae 30 genera 55 species: total 54 genera 91 species. 5. Dominant species were Anacystis aeruginosa, Lyngbya contorta, Anabeana Sp, Melosira granulata, Melosira granulata var. angustissima, Dictyosphaerium pulchellurn and Actinastrurn hantzschii var. fiuviatile during the period from summer to fall. 6. Lyngbya contorta was seemed to adapt to the circumstance of low transparency. 7. Phytoplankton distributions were seemed to be influenced by salinity and thransparency. And so they might appear much fewer in the downstream than the upperstream in Yongsan lake.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.9
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• pp.3449-3467
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• 2015

A broadcast operation is the fundamental transmission technique in mobile ad-hoc networks (MANETs). Because a broadcast operation can cause a broadcast storm, only selected forwarding nodes have the right to rebroadcast a broadcast message among the one-hop and two-hop neighboring nodes of a sender. This paper proposes the maximum intersection self-pruning (MISP) algorithm to minimize broadcasting redundancy. Herein, an example is given to help describe the main concept of MISP and upper bounds of forward node have been derived based on induction. A simulation conducted demonstrated that when conventional blind flooding (BF), self-pruning (SP), an optimized link state routing (OLSR) multipoint relay (MPR) set, and dominant pruning (DP), are replaced with the MISP in executing Strong duplicate address detection (DAD), the performances in terms of the energy consumption, upper bounds of the number of forward nodes, and message complexity have been improved. In addition, to evaluate the performance in reference to the link error probability, P_e, an enhancement was achieved by computing a proposed retransmission limit, S, for error recovery based on this probability. Retransmission limit control is critical for efficient energy consumption of MANET nodes operating with limited portable energy where Strong DAD reacts differently to link errors based on the operational procedures.

• Korean Journal of Environmental Biology
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• v.32 no.4
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• pp.286-296
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• 2014

In this study, we investigated the macrobenthic community structure and spatiotemporal variations in Uljin Marine Ranching area, East Sea of Korea. Macrobenthos were collected using a modified van Veen grab sampler from April to September 2013. Total number of species sampled was 345 and mean density was 5,797 ind. $m^{-2}$, both of which were dominated by the polychaetes. The most dominant species were Spiophanes bombyx (53.64%), followed by Magelona sp.1 (6.96%), Cadella semitorta (2.73%), Lumbrineris longifolia (2.16%) and Alvenius ojianus (2.08%). Cluster analysis and nMDS ordination analysis based on the Bray-Curtis similarity identified 2 station groups. The group 1 (station 2, 3, 5, 6, 8 and 9) was characterized by high abundance of the polychaetes Magelona sp.1, Lumbrineris longifolia, Scoloplos armiger, Praxillella affinis, Maldane cristata and the bivalve Alvenius ojianus, with fine sediment above 30m water depth. On the other hand, the group 2 (station 1, 4, 7 and 10) was numerically dominated by the polychaete Lumbrineriopsis sp. and the bivalve Cadella semitorta, with coarse sediment below 5m water depth. Collectively, the macrobenthic community structure showed a distinct spatial trend, which seemed to be related to the water depth and sediment composition.

• Korean Journal of Food Science and Technology
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• v.38 no.1
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• pp.82-87
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• 2006

Twenty one strains strongly producing protease were isolated from Korean traditional Cheonggukjang. Eight strains selected by sensory evaluation on Cheonggukjang prepared with isolated strains were identified with based on biochemical properties a and 16S rDNA sequencing. Identified strains were Bacillus subtilis MB4, and Bacillus amyloliquefaciens A1, A2, B1, MC1, SB2, SC1, and SD1. Protease activities, important strain selection factor, were higher in Cheongjukjang prepared with B. subtilis MB4 (179.6 Unit) and B. amyloliquefaciens SB2 (201.9 Unit) than commercial traditional Cheonggukjang (97.9 Unit). Sensory evaluation revealed Cheonggukjang prepared with B. subtilis MB4 had flavor very similar to commercial traditional Cheonggukjang. Cheonggukjang prepared with B. suhtilis MB4 (0.0006 Pa s) and commercial traditional Cheonggukjang (0.0002 Pa s) revealed lower viscosities than those of Cheonggukjang prepared with B. amyloliquefaciens SB2, MC1, B1, A1, SD1, A2, and SC1 (0.006 to 0.008 Pa s at 1001/s. Results show Cheonggukjang could be prepared using single strain of B. subtilis MB4, maintaining high protease activity and very similar sensory and viscosity qualities with those of commercial traditional Cheonggukjang.

• Tuberculosis and Respiratory Diseases
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• v.84 no.2
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• pp.125-133
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• 2021

Background: The coronavirus disease (COVID-19) can manifest in a range of symptoms, including both asymptomatic systems which appear nearly non-existent to the patient, all the way to the development of acute respiratory distress syndrome (ARDS). Specifically, COVID-19-associated pneumonia develops into ARDS due to the rapid progression of hypoxia, and although arterial blood gas analysis can assist in halting this deterioration, the current environment provided by the COVID-19 pandemic, which has led to an overall lack of medical resources or equipment, has made it difficult to administer such tests in a widespread manner. As a result, this study was conducted in order to determine whether the levels of oxygen saturation (SpO₂) and the fraction of inhaled oxygen (FiO₂) (SF ratio) can also serve as predictors of ARDS and the patient's risk of mortality. Methods: This was a retrospective cohort study conducted from February 2020 to Mary 2020, with the study's subjects consisting of COVID-19 pneumonia patients who had reached a state of deterioration that required the use of oxygen therapy. Of the 100 COVID-19 pneumonia cases, we compared 59 pneumonia patients who required oxygen therapy, divided into ARDS and non-ARDS pneumonia patients who required oxygen, and then investigated the different factors which affected their mortality. Results: At the time of admission, the ratios of SpO₂, FiO₂, and SF for the ARDS group differed significantly from those of the non-ARDS pneumonia support group who required oxygen (p<0.001). With respect to the predicting of the occurrence of ARDS, the SF ratio on admission and the SF ratio at exacerbation had an area under the curve which measured to be around 85.7% and 88.8% (p<0.001). Multivariate Cox regression analysis identified that the SF ratio at exacerbation (hazard ratio [HR], 0.916; 95% confidence interval [CI], 0.846-0.991; p=0.029) and National Early Warning Score (NEWS) (HR, 1.277; 95% CI, 1.010-1.615; p=0.041) were significant predictors of mortality. Conclusion: The SF ratio on admission and the SF ratio at exacerbation were strong predictors of the occurrence of ARDS, and the SF ratio at exacerbation and NEWS held a significant effect on mortality.