• Title/Summary/Keyword: SM130

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The Stability of Aspalatone and Aspirin in Buffered Aqueous Solution (완충 수용액중 아스파라톤 및 아스피린의 안정성)

  • 곽혜선;전인구
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1995.04a
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    • pp.130-130
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    • 1995
  • AM, SM 및 ASA는 수용액중에서 겉보기 1차반응에 따라 분해되었으며 보존온도가 높을수록 분해가 촉진되는 온도 의존성을 나타내었다. AM의 분해경로는 pH 1.22 및 pH 7.0 이상에서는 AM$\longrightarrow$ SM $\longrightarrow$ SA의 경로로 주로 분해되었으며 pH 2.01 - 6.08의 범위에서는 AM $\longrightarrow$ASA$\longrightarrow$SA의 경로로 분해되는 양상을 보였다. 또 pH가 분해에 미치는 영향을 pH-rate profile로 나타낸 결과 AM, SM 및 ASA의 최대안정 pH는 각각 4.0, 3.0, 2.0 부근이 있고 이 조건에서의 분해 반감기는 114, 168, 113 hr로 나타났다. 전체적으로 보면 pH 2.0 이하에서는 ASA가 AM 보다 약간 안정한 편이나 pH 2.0-8.0 사이에서는 AM의 분해속도가 ASA보다 현저히 낮았다. 또 AM은 pH 7.0 이상에서, SM은 pH 6.0 이상에서, ASA는 9.0 이상에서 특수염기촉매반응에 따라 분해가 이루어지는 것을 알 수 있었다. 이온강도($\mu$)의 영향으로는 pH 7.0에서 이온강도가 0.115에서 1.0으로 증가할수록 $\mu$$^{1}$2/에 대해 AM의 분해속도정수가 직선적으로 완만하게 감소되었다. 또 완충수용액 중 AM의 가수분해 억제효과를 검토하기 위해 시클로덱스트린류를 첨가하였을 때, $\beta$-시클로덱스트린과 히드록시프로필기-$\beta$-시클로덱스트린은 AM의 분해를 각각 1.6배 및 1.1배 촉진시켜 촉매적으로 작용하였으며 디메칠-$\beta$-시클로덱스트린은 약 3.2배 분해속도를 억제시켜 안정화제로 작용하였다.Zn^{2+}$, soybean trypsin inhibtor에 의해 25~50% 정도, serine proteinase inhibitor인 phenylmethylsulfonyl floride에 의해 80%정도 활성이 억제되는 특성이 있음을 규명하였다.면역환성 (immunoreactivity)이 나타났고 pyramidal cell layer (PCL)와 glia에 SOD-1이 강하게 염색되었다. APT 병용 투여로 상당수의 경련이 일어나지 않은 흰쥐는 해마의 DG에 FRA가 경미하게 염색되었고, PCL에 SOD-1도 경미하게 나타났으나, 경련이 나타난 쥐에서는 KA만을 투여한 흰쥐와 구별되지 않았다. 이상의 APT의 항산화 효과는 KA로 인한 뇌세포 변성 개선에 중요한 인자로 작용할 것으로 사료되나, 보다 명확한 APT의 기전을 검색하고 직접 임상에 응응하기 위하여는 보다 다양한 실험 조건이 보완되어야 찰 것으로 생각된다. 항우울약들의 항혈소판작용은 PKC-기질인 41-43 kD와 20 kD의 인산화를 억제함에 기인되는 것으로 사료된다.다. 것으로 사료된다.다.바와 같이 MCl에서 작은 Dv 값을 갖는데, 이것은 CdCl$_{4}$$^{2-}$ 착이온을 형성하거나 ZnCl$_{4}$$^{2-}$ , ZnCl$_{3}$$^{-}$같은 이온과 MgCl$^{+}$, MgCl$_{2}$같은 이온종을 형성하기 때문인것 같다. 한편 어떠한 용리액에서던지 NH$_{4}$$^{+}$의 경우 Dv값이 제일 작았다. 바. 본 연구의 목적중의 하나인 인체유해 중금속이온인 Hg(II), Cd(II)등이 NaCl같은 염화물이 함유된 시료용액에 공해이온으로 존재할 경우 흡착에 의한 제거가 가능하다. 한편 이같

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Automatic recognition of the old and the infirm using Arduino technology implementation (아두이노를 사용하여 노약자 자동 인식 기술 구현)

  • Choi, Chul-kil;Lee, Sung-jin;Choi, Byeong-yoon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2014.05a
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    • pp.454-457
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    • 2014
  • Arduino is for design based on open source prototyping platform, artist, designer, hobby activists, etc, i has been designed for all those who are interested in the environment construct. Arduino adventage you can easily create applications hardware, without deep knowledge about the hardware. Configuration of arduino using AVR microcontroller ATmage 168, software to action arduino using arduino program, MATLAB, Processing. Arduino is open source base, you can hardware production directly and using shield additionally, the arduino can be combined. Android is open source. Continue to expand through a combination of hardware, Arduino. It name is shield. Be given to the Arduino Uno board to the main board, the shield extends to the various aspects and help can be equipped with more features. The shield on top of the shield can be combined as a kind of shield and Ethernet shield, motor shield, the shield RFID hardware beyond a simple extension can be configured. In this paper, RFID technology Sealed for automatic recognition of the elderly by the elderly to identify and tag them SM130 13.56Mhz compatible hardware was constructed by combining tags.

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THE CONCENTRATION OF PCDD/FS IN FLUE GAS AND SOIL COLLECTED IN THE VICINITY OF VARIOUS INCINERATORS, KOREA

  • Kim, Kyoung-Soo;Kim, Kyeo-Keun;Kim, Jong-Guk
    • Environmental Engineering Research
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    • v.12 no.2
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    • pp.55-63
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    • 2007
  • PCDD/Fs monitoring was carried out to estimate the contamination level in soil samples taken in the vicinity of the various incinerators throughout South Korea from July 2003 to December 2004. The levels ranged from N.D. to 130.39 pg I-TEQ/g (d.w.) with an average concentration of 11.38 pg I-TEQ/g (d.w.). The level of PCDD/Fs in this study is similar to that of other countries. Overall, the highest mean concentration in the soil was found at 250 m from the stack. In addition, the flue gases were analyzed in order to obtain the congener profiles of the PCDD/Fs emitted from the incinerators. The concentration of I-TEQ in the flue gas ranged from 0.33 to 21.5 ng TEQ/$Sm^3$. These levels were much lower than the concentration stipulated in the Korean emission criterion(40 ng TEQ/$Sm^3$ until 2005). The comparison of the congener patterns using cluster analysis showed that the incinerators and PCP are sources of PCDD/Fs in the soil samples according to the sampling point, but the possibility of unidentified combustion sources and vehicles exists in the case of complex industrial regions.

Activity of virE promoter in Agrobacterium tumefaciens A348 (Agrobacterium tumefaciens A348에서 virE 프로모터의 활성)

  • 음진성
    • Journal of Plant Biology
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    • v.34 no.4
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    • pp.331-339
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    • 1991
  • To elucidate the regulatory mechanism of virE operon from vir regions (virA, virB, virC, virD, virG, virE) of pTiA6 which have been known to be essential for efficient crown gall tumorigenesis in plants, the activity of the truncated virE, promoter was analyzed. pSM358cd, a recombinant plasmid in which virE :: Tn3-HoHo1 (Tn3-promoterless lacZ) was cloned into SalI site of pVK102, was digested with SalI, and virE :: Tn3-HoHo1 was seperated from pVK102. To construct the truncted virE recombinant plasmids (pJS031, pJS051, pJS102, pJS201, pJS301), 5'-end of vireE promoter was deleted with BAL31 and cloned into pVK102 and then transferred into a. tumefaciens A348(pTiA6). According to the activity of the truncated virE promoter in recombinant plasmids, they were classified into two groups, pJS031, pJS051, pJS101 and pJS201 belong to a functional group and pJS301 is a non-functional. The size of deleted nucleotides of pJS201 and pJS301 seemed to be about 130 nucleotides and about 250 nucleotides from 5'-end of virE promoter, respectively. Hence it was thought that the essential site of the virE promoter was located between about 130th nucleotide and 250th nucleotide from 5'-end of the virE promoter.

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A Study on the Micro Turning Machinability of A1-Mg Alloy Using Polycrystalline Diamond Tool (다결정 다이아몬드 공구를 이용한 Al-Mg계 합금의 미소선삭가공특성에 관한 연구)

  • Hwang, Joon;Namgung, Suk
    • Journal of the Korean Society for Precision Engineering
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    • v.13 no.5
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    • pp.122-130
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    • 1996
  • In this study, machinability of some aluminum-magnesium alloy are experimentally investigated using polycrystalline diamond tool with turning, and evaluated some independent cutting variables affected micrometal cutting characteristics as cutting force, specific cutting resistance, shear angles. To know the effect of cutting parameters of single point diamond machining, experiments were performed to measure cutting forces for high speed turning of aluminum alloy 6061-T6, SM45C and FC20 with poly- crystalline diamond and coated cemented carbide tool. Independent cutting variables were changed to a variety of cutting speed, feed rate, rake angles, material properties of workpiece and tool. Futhermore. Some useful informations are obtained in this study can guide micro metal cutting of aluminum alloy with diamond tool.

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Evaluation of marginal discrepancy in metal frameworks fabricated by sintering-based computer-aided manufacturing methods

  • Kaleli, Necati;Ural, Cagri;Us, Yesim Olcer
    • The Journal of Advanced Prosthodontics
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    • v.12 no.3
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    • pp.124-130
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    • 2020
  • PURPOSE. The aim of this in vitro study was to evaluate the effect of sintering procedures on marginal discrepancies of fixed partial metal frameworks fabricated using different sintering-based computer-aided design and computer/aided manufacturing (CAD/CAM) techniques. MATERIALS AND METHODS. Forty resin die models of prepared premolar and molar abutment teeth were fabricated using a three-dimensional (3D) printer and divided into four groups (n = 10) according to the fabrication method of metal frameworks used: HM (via hard milling), SM (via soft metal milling), L25 (via direct metal laser melting [DMLM] with a 25 ㎛ layer thickness), and L50 (via direct DMLM with a 50 ㎛ layer thickness). After the metal frameworks were fabricated and cemented, five vertical marginal discrepancy measurements were recorded in each site (i.e., buccal, facing the pontic, lingual, and facing away from the pontic) of both abutment teeth under a stereomicroscope (×40). Data were statistically analyzed at a significance level of 0.05. RESULTS. No statistically significant differences (P>.05) were found among the four axial sites of metal frameworks fabricated by sintering-based CAD/CAM techniques. The HM and L25 groups showed significantly (P<.001) lower marginal discrepancy values than the SM and L50 groups. CONCLUSION. Marginal discrepancy in the sites facing the pontic was not influenced by the type of sintering procedure. All fabrication methods exhibited clinically acceptable results in terms of marginal discrepancies.

Design and Implementation of a Home Network System on OpenWrt using Android Remote Control (OpenWrt와 Android 연동 원격 홈 네트워크 제어 시스템 설계 및 구현)

  • Kim, Cheong Ghil
    • Journal of Satellite, Information and Communications
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    • v.7 no.3
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    • pp.130-134
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    • 2012
  • This paper introduces a home network service system using a low-cost wireless router on OpenWrt which can be remotely controled by Android devices. The proposed system consists of an embedded system development platform for home network service control based on OpemWrt embedded Linux, an embedded system development platform, a remote control on Android, and a home linghting device made by an interface board with LEDs. The prototype system is made of a wireless router of Buffalo, WZR-HP-G450H, Arduino Uno interface board with LEDs, and an Android development kit of HBE-SM5-S421. The operation was performed by TCP/IP programming for Android remote control, socket programming between Android development kit and wireless router, and UART communication programming between the interface board and wireless router. The implementation result shows that a low cost home network systme could be implemented with a wireless router.

Precambrian Kyeonggin gneiss complex (선캠브리아 경기육괴 중 대리암의 연대측정에 대한 예비연구)

  • 박계헌;정창식
    • The Journal of the Petrological Society of Korea
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    • v.2 no.2
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    • pp.130-138
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    • 1993
  • Kyeonggi Gneiss complex forming Korean Precambrian basement is mainly composed of high-grade metasedimentary rocks, which are generally difficult to determine their absolute ages. We examined the feasibility of successive absolute age determination method for the marbles from this basement. We used hydrochloric acid for the selective dissolution of carbonate minerals from the marbles. Trace element analysis shows that most of Zr and Rb are concentrated in the residues. U in the residue is more abundant than that in HC1-dissolved parts. Pb, Sr, Sm, and Nd are somewhat evenly distributed between HC1-dissolved parts and the residues. }Th shows rather complex behavior. Sr isotopic compositions of the HC1-dissolved parts reveal mixing with Sr from non-carbonate minerals having much higher $^{87}Sr/^{86}Sr$ ratios. We suggest that the most reliable method in the age determination for the marbles of this area is measuring Pb isotopic ratios of the pieces of pure marbles.

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Physicochemical changes and plant growth effect on composting of spent mushroom substrates (버섯수확후배지의 퇴비화에 따른 물리 화학적 변화 및 식물 생육 효과)

  • Song, Ji-Min;Phong, Nguyen Hong;Kim, Ja-Yoon;Kang, Dae-Sun;Yu, Jeong-Yeon;Kang, Hee-Wan
    • Journal of Mushroom
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    • v.18 no.3
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    • pp.268-273
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    • 2020
  • This study aimed to assess the feasibility of composting spent mushroom substrate (SMS) materials of Lentinula edodes (Le), Hericium erinaceus (He), and Pleurotus ostreatus (Po). The different SMSs were composted for 7 to 10 days at high temperatures over 50℃; the composting procedure was completed in 30 days. A maturity test was conducted using the radish seed germination index and CoMMe-100. The composted SMS (CSMS) from Le and He showed gemination indices of 130% and 81%, respectively, that satisfied the criteria of maturity standard (gemination index over 70%) and the CoMMe-100 analysis. The physicochemical changes of CSMSs included an increase in the pH range from 4-5 to 6-7, slight reduction in the EC to 1-1.4 dS/m, and an organic content of 36.9% in LeCSMS. In LeCSMS, the contents of N, P, and K were 1.2%, 2.3%, and 0.77%, respectively, and heavy metals were detected below the standard value in all CSMSs; the Ca and Mg contents in the CSMSs were increased from 30% to 60% when compared to those in the SMSs. The C/N ratio (from 26-33) in LeSMS and HeSMS decreased to 15.3-15.9 in CSMSs. The growth effect of LeCSMS treatment on pepper seedlings was 60% higher than that in the control groups, one of which was treated with commercial organic compost; the former showed a superior growth effect on the leaf width, leaf length, and leaf number compared to other control groups. In conclusion, LeCSMS and HeCSMS could be utilized as compost resources capable of efficient soil amendment and plant growth promotion.