• Title/Summary/Keyword: SIR Model

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Coronary Arterial Lesions of Kawasaki Disease Observed in a Mouse Model of Sepsis: A Pilot Study and a Review of the Literature (패혈증 마우스 모델에서 가와사키병의 관상동맥 병변 관찰: 예비연구와 문헌고찰)

  • Kim, Joo-Hyun;Kim, Hyo-Jin;Shin, Jung-Ha;Choi, Ui-Yoon;Lee, Soo-Young;Han, Ji-Whan
    • Pediatric Infection and Vaccine
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    • v.24 no.2
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    • pp.102-107
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    • 2017
  • Purpose: Coronary arterial lesions (CALs) were reported to have developed in children with systemic inflammatory diseases, as well as those with Kawasaki disease (KD). The purpose of this study was to confirm that the CAL development in children with KD occurs in a mouse model of sepsis presenting typical systemic inflammatory response syndrome (SIRS). Methods: To induce the sepsis mouse model with SIRS, 6-week-old C57BL/6 mice were intraperitoneally injected with endotoxin. We compared histological findings of the major organs between the control and the sepsis groups and examined CAL in the heart of the septic mice. Results: Infiltrating inflammatory cells were relatively increased in the heart, liver, and kidneys of the sepsis group, compared with those of the control group. We confirmed lymphocytic infiltration in the myocardium (myocarditis) and the pericardial soft tissue of the heart. Furthermore, coronary artery of the septic mouse was identified, but CAL was not observed. Conclusions: In this study, we failed to confirm the existence of CAL in a mouse model of sepsis. However, it is well-known that CALs are seen in many kinds of diseases that cause SIRS. Our findings suggest further investigation into the clinical significance of CAL in various systemic inflammatory diseases, including KD.

Theoretical and Experimental Study on the, Dynamic Behavior of Continuous Bridge having Irregular Surface under-Moving Load (불규칙한 노면(路面)을 주행하는 이동하중에 의한 연속교의 동적거동에 관한 이론 및 실험적 연구)

  • Chang, Sung Pil;Yhim, Sung Soon;Jo, Sir Kyung
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.9 no.3
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    • pp.21-30
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    • 1989
  • In this study, the dynamic behavior of a continuous bridge under moving load is studied considering roughness of the road surface. Vehicle model includes the spring effects of axes, and due to these effects, equations of motions for the vehicle and bridge are derived in coupled form. And then iteration method is used to solve the equations. In experimental study a bridge model is constructed considering the similarity rule in order that the model exhibits dynamic behavior similar to that of prototype. Three types of roughness such as uneven random roughness, uplift on the approach and piece-wise constant roughness are used to describe road roughness. Through the numerical analysis and experiments, the effects of surface roughness, sprung mass, and velocity on the dynamic behavior of the bridge are examined.

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RFM으로 생성된 레이더 정사영상 자료의 정확도 분석

  • 이선일;김윤형;이규성
    • Proceedings of the Korean Association of Geographic Inforamtion Studies Conference
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    • 2003.04a
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    • pp.121-128
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    • 2003
  • 사면관측 원리에 의해 획득되는 레이더 영상은 레이더파의 입사각도와 지표면의 경사도 및 방위각에 따라 기하학적 왜곡이 발생하게 된다. 전 국토의 70% 이상이 산악지형인 국내 여건을 감안한다면 레이더 영상의 정량적 활용을 위해서는 정밀한 기하보정이 반드시 필요하다. 본 연구에서는 RADSARSAT-1 SAR 영상에 대하여 세 가지 기하보정 방법을 적용하였다. 먼저 GCP 만을 이용한 단순기하보정을 수행하였고, 두번째로 위성의 자세와 위치정보 등을 이용하여 센서모델을 통한 보정을 하였다. 마지막으로 다양한 영상자료에 적용할 수 있는 RFM(Rational Function Model)을 이용하여 기하보정을 하였다. 이 세 가지 방법으로 기하보정된 레이더 영상의 위치정확도를 모의 레이더 영상과 비교 분석하였다. 또한 RFM을 이용한 보정결과를 검증하기 위하여 SIR-C 영상을 추가로 분석하였다.

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Numerical Analysis and Experimental Study for Low Reynolds number region around Micro Air Vehicle (초소형 비행체 주위의 저 레이놀즈수 영역에 대한 수치 해석 및 실험적 연구)

  • Kim Y. H.;Kim W. R.;Kim C.;Rho O. H.
    • 한국전산유체공학회:학술대회논문집
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    • 2002.05a
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    • pp.53-58
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    • 2002
  • A three-dimensional incompressible Navier-Stokes solver is developed for the flow analysis around Micro Air Vehicle(MAV) designed by MACDL(Micro Aerodynamic Control and Design Lab), Seoul National Univ., Validations of this solver are presented for two cases, first flow over the circular cylinder with infinite length, second flow over infinite wing with wing section, E387 airfoil. Simultaneously, Wind Tunnel test is performed with Flatform Wire type sir-component balance and model designed by MACDL. The numerical results are also examined through comparison with experimental data.

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Modeling and Network Simulator Implementation for analyzing Slammer Worm Propagation Process (슬래머 웜 전파과정 분석을 위한 네트워크 모델링 및 시뮬레이터 구현)

  • Lim, Jae-Myung;Yoon, Chong-Ho
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.32 no.5B
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    • pp.277-285
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    • 2007
  • In this paper, we present a simulation model of Slammer worm propagation process which caused serious disruptions on Internet in the you of 2003 and analyze the process of Slammer by using NS-2. Recently introduced NS-2 modeling called "Detailed Network-Abstract Network Model" had enabled packet level analysis. However, it had deficiency of accommodating only small sized network. By extending the NS-2 DN-AN model to AN-AN model (Abstract Network-Abstract Network model), it is effectively simulated that the whole process from the initial infection to the total network congestion on hourly basis not only for the Korean network but also for the rest of the world networks. Furthermore, the progress of the propagation from Korean network to the other country was also simulated through the AN-AN model. 8,848 hosts in Korean network were infected in 290 second and 66,152 overseas hosts were infected in 308 second. Moreover, the scanning traffics of the worm at the Korean international gateway saturated the total bandwidth in 154 seconds for the inbound traffic and in 135 seconds for the outbound one.

Heat and mass transfer analysis in air gap membrane distillation process for desalination

  • Pangarkar, Bhausaheb L.;Sane, Mukund G.
    • Membrane and Water Treatment
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    • v.2 no.3
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    • pp.159-173
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    • 2011
  • The air gap membrane distillation (AGMD) process was applied for water desalination. The main objective of the present work was to study the heat and mass transfer mechanism of the process. The experiments were performed on a flat sheet module using aqueous NaCl solutions as a feed. The membrane employed was hydrophobic PTFE of pore size 0.22 ${\mu}m$. A mathematical model is proposed to evaluate the membrane mass transfer coefficient, thermal boundary layers' heat transfer coefficients, membrane / liquid interface temperatures and the temperature polarization coefficients. The mass transfer model was validated by the experimentally and fitted well with the combined Knudsen and molecular diffusion mechanism. The mass transfer coefficient increased with an increase in feed bulk temperature. The experimental parameters such as, feed temperature, 313 to 333 K, feed velocity, 0.8 to 1.8 m/s (turbulent flow region) were analyzed. The permeation fluxes increased with feed temperature and velocity. The effect of feed bulk temperature on the boundary layers' heat transfer coefficients was shown and fairly discussed. The temperature polarization coefficient increased with feed velocity and decreased with temperature. The values obtained were 0.56 to 0.82, indicating the effective heat transfer of the system. The fouling was observed during the 90 h experimental run in the application of natural ground water and seawater. The time dependent fouling resistance can be added in the total transport resistance.

Run-flat Tire Optimization Using Response Surface Method and Genetic Algorithm (반응표면법과 유전자 알고리듬을 이용한 런플랫 타이어 최적화)

  • Choi, Jaehyeong;Kang, Namcheol
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.25 no.4
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    • pp.247-254
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    • 2015
  • Ride comfort is one of the major factors in evaluating the performance of the vehicle. Tire is closely related to the ride comfort of the vehicle as the only parts in contact with the road surface directly. Vertical stiffness which is one of the parameters to evaluate the tire performance is great influence on the ride comfort. In general, the lower the vertical stiffness, the ride comfort is improved. Research for improving the ride comfort has been mainly carried out by optimizing the shape of the pneumatic tire. However, demand for safety of the vehicle has been increased recently such as a run-flat tire which is effective in safety improvement. But a run-flat tire have trouble in practical use because of poor ride comfort than general tire. Therefore, In this paper, the research was carried out for improving the ride comfort through the optimization of the SIR shape inside a run-flat tire. Meta-model was generated by using the design of experiment and it was able to reduce the time for the finite element analysis of optimization. In addition, Shape optimization for improving the ride comfort was performed by using the genetic algorithm which is one of the global optimization techniques.

Scale Model Experiment on Daylighting of Differentiated Glazing System (축소모형을 이용한 분할형 유리 투과체 창호시스템의 채광성능실험)

  • Jeong, In Young;Kim, Jeong Tai
    • KIEAE Journal
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    • v.4 no.4
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    • pp.61-68
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    • 2004
  • Daylight is a critical factor in architecture, as it helps enhance the working efficiency and pleasantness of the people working inside, in addition to reduce the power consumption in heating and cooling and make the interior space brighter. There are many kinds of glazing and daylighting systems. At present, research and efforts for their development are carried out, alongside quantitative evaluation. This study aims to present basic materials to be used to design proper glazing and daylighting systems in architecture based on a quantitative evaluation by scale models of existing office buildings. The result of the study can be summarized as follows. 1)As a result of the experiment, it appeared that the ratio of the interior illumination (i.e. at the working table, ceiling and wall) against the outdoor illumination increases at a constant rate, as the transmittance of the glazing goes up. 2) It was found that the SIR(Sunlight Illuminance Ratio) of a separated window system goes up by 20-50% at the rear part than in the case of an ordinary window system.

Simulation and Analysis of Slammer Worm Propagation With Automatic Quarantine (자동 격리를 감안한 슬래머 웜 전파과정에 대한 모의실험 및 분석)

  • Lim, Jae-Myung;Jung, Han-Gyun;Yoon, Chong-Ho
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.32 no.8B
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    • pp.529-538
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    • 2007
  • In this paper, we have analyzed a simulation model of Slammer worm propagation process which caused serious disruptions on the Internet in the year of 2003 by using NS-2. Previously we had presented and analyzed Abstract Network to Abstract Network(AN-AN) model being modified from the Detailed Network to Abstract Network(DN-AN) of NS-2. However, packet analysis in AN-AN model had a problem of taking 240 hours to simulate the initial 300 seconds of infection. We have reduced the AN-AN model to save the simulation time and analyzed total 3.5 hours of the network congestions within 107 hours. Moreover, we have derived optimal quarantine rate of 0.0022 considering service outage of network devices caused by the heavy infected traffics, which was not taken into consideration in previous works. As the result of simulation, Although the inbound traffic at the Korean international gateway was back in normal conditions at 4,787 second, due to the revese direction saturation was maintained until 12,600 seconds, the service outage was persisted for 3.5 hours.

FEM-based modelling of stabilized fibrous peat by end-bearing cement deep mixing columns

  • Dehghanbanadaki, Ali;Motamedi, Shervin;Ahmad, Kamarudin
    • Geomechanics and Engineering
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    • v.20 no.1
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    • pp.75-86
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    • 2020
  • This study aims to simulate the stabilization process of fibrous peat samples using end-bearing Cement Deep Mixing (CDM) columns by three area improvement ratios of 13.1% (TS-2), 19.6% (TS-3) and 26.2% (TS-3). It also focuses on the determination of approximate stress distribution between CDM columns and untreated fibrous peat soil. First, fibrous peat samples were mechanically stabilized using CDM columns of different area improvement ratio. Further, the ultimate bearing capacity of a rectangular foundation rested on the stabilized peat was calculated in stress-controlled condition. Then, this process was simulated via a FEM-based model using Plaxis 3-D foundation and the numerical modelling results were compared with experimental findings. In the numerical modelling stage, the behaviour of fibrous peat was simulated based on hardening soil (HS) model and Mohr-Coulomb (MC) model, while embedded pile element was utilized for CDM columns. The results indicated that in case of untreated peat HS model could predict the behaviour of fibrous peat better than MC model. The comparison between experimental and numerical investigations showed that the stress distribution between soil (S) and CDM columns (C) were 81%C-19%S (TS-2), 83%C-17%S (TS-3) and 89%C-11%S (TS-4), respectively. This implies that when the area improvement ratio is increased, the share of the CDM columns from final load was increased. Finally, the calculated bearing capacity factors were compared with results on the account of empirical design methods.