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Evaluation of vaccination against Mycoplasma hyopneumoniae in pigs at different vaccination time-points (돼지 마이코플라즈마 폐렴 예방백신의 접종시기별 방어효과에 관한 연구)

  • Lee, Ham-Hee;Rha, James;Han, Jeong-Hee
    • Korean Journal of Veterinary Service
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    • v.31 no.3
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    • pp.291-303
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    • 2008
  • This study was performed to evaluate the effect of commercial swine mycoplasma vaccine (M+$Pac^{(R)}$, Schering-Plough Animal HealthCo.) at different vaccination time points. Total 139 piglets were moved to experimental farm after weaning and were randomly allocated to 3 treatment groups and 1 control group. Piglets of 3 treatment groups (A, B and C) were vaccinated twice at 1 and 3 weeks (A group), 3 and 5 weeks (B), and 6 and 8 weeks (C), respectively. All vaccinates showed higher antibody titers compared with nonvaccinates, and maintained to finish (P<0.001). Performance and RBC/WBC count showed no significant difference between groups. Vaccinates at 6-8 weeks showed better effect on decrease of clinical sign compared with vaccinates at 1-3 weeks and 3-5 weeks and nonvaccinates. Also, lung lesion assessment showed significant difference between vaccinates at 3-5 weeks and 6-8 weeks, and nonvaccinates and vaccinates at 1-3 weeks (P<0.05). Vaccinates at 3-5 score in comparison with other groups. In conclusion, these results suggested that vaccination at 3-5 weeks or later may be more effective than earlier vaccination.

Gemini/GMOS Observation of Extended Star Clusters in Dwarf Irregular Galaxy NGC 6822

  • Hwang, Narae;Park, Hong Soo;Lee, Myung Gyoon;Lim, Sungsoon;Hodge, Paul W.;Kim, Sang Chul;Miller, Bryan;Weisz, Daniel
    • The Bulletin of The Korean Astronomical Society
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    • v.39 no.2
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    • pp.55.1-55.1
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    • 2014
  • on the observation with the Gemini Multi-Object Spectrograph on the Gemini-South 8.1 m telescope. The radial velocities of four ESCs do not display any sign of systematic motion, unlike the intermediate age carbon stars in NGC 6822. The ages and metallicities derived using the Lick indices show that the ESCs are old (>=8 Gyr) and metal poor ([Fe/H] <= -1.5). NGC 6822 is found to have both metal poor ($[Fe/H]{\approx}-2.0$) and metal rich ($[Fe/H]{\approx}-0.9$) star clusters within 15' (2 kpc) from the center, whereas only metal poor clusters are observed in the outer halo with r >= 20'(2.6 kpc). Based on the kinematics, old ages, and low metallicities of ESCs, we discuss the possible origin of ESCs and the formation of the outer halo of a small dwarf irregular galaxy NGC6822.

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A Study on the Usefulness of Characteristic Past History Investigation for Life Care in People with Lumbar Instability (허리부위 불안정성자 라이프케어를 위한 특징적과거력 조사의 유용성에 관한 연구)

  • Ki, Chul;Heo, Myoung;Song, Seong-Min
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.8
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    • pp.583-593
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    • 2019
  • The purpose of this study was to investigate the relation between and subjective instability pain behavior (SIPB) and physical instability test(PIT) according to the presence of characteristic past histories(CPH) in people with chronic low back pain(CLBP). Forty CLBP subjects participated in this study. The presence of four characteristics past histories(long term history, traumatic experience, sports activities, neurologic sign) were examined. According to presence number(PN) of CPH, subjects were divided into 5 groups[group 1(PN:0): n=8, group 2(PN:1): n=8, group 3(PN:2): n=8, group 4(PN:3): n=8, group 5(PN:4): n=8]. After 16 items were examined for the SIPBs, then Seven PITs were conducted, and the results were scored. The SIPBs and PITs were compared according to the presence numbers of CPH, and the relation between them was analyzed. There was a significant difference(p<.05) in both SIPB scores and PIT scores in the comparison of groups according to the presence number of CPH. There was high positive correlation between the presence numbers of CPH and SIPB score(r=.819, p=.000) and PIT score(r=.606, p=.000). Also, there was a correlation between SIPB score and PIT score(r=.571, p=.000). Based on the findings in the present study, the presence of three or more CPH in people with CLBP may be a useful variable in the diagnosis of lumbar instability. The combined findings of the three variables such as CPH, SIPB, and PIT can improve the accuracy of lumbar instability diagnosis.

Renal failure associated with ingestion of grapes and raisins in dogs (개에서 포도 및 건포도 섭취가 신부전에 미치는 영향)

  • Yuk, Jin-yub;Kim, Cheol-ho;Kim, Tae-yung;Kang, Chung-boo
    • Korean Journal of Veterinary Research
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    • v.45 no.2
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    • pp.287-296
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    • 2005
  • This experiments was designed to observe the effect of period and dose of ingestion of grapes on renal failure in dog. After the dogs had been mixed of general feed, raisins from U.S.A and fresh grapes from Chile selling in Korea. We observed the clinical sign, and analyzed the blood and urine using by biochemical test. The experiment was executed by the two following groups. The experiment group 1. derived renal failure by supplying the mixed general feed with fresh grapes and dry grapes 15 g per weight kg, 2 times a day (AM 09, PM 21), the experiment group 2. executed to derive renal failure by supplying the mixed general feed with fresh grapes and dry grapes 40 g per weight kg, 2 times a day. Extraction of blood for analysis was conducted one time a day and clinical test for renal failure was executed by means of a blood analysis, biochemical analysis, urine analysis, excretory urography (E.U) and E.R.D-$screen^{TM}$ urine test (Heska, USA). The results of group 1 were normal ranges (BUN 9.0~22.6 mg/dl, creatinine 0.8~1.2 mg/dl, Ca 9.7~12.3 mg/dl, Pi 2.9~4.6 mg/dl), renal failure was not observed. On the 3rd day in group 2, azotemia was arisen from the increasing BUN 83 mg/dl (7~25 mg/dl), creatinine 2.3 mg/dl (0.5~1.4 mg/dl), when executed urine was tested by E.R.D-$screen^{TM}$ test using in the early kidney disease diagnosis, microalbumine state was high positive, and it showed stale delay by using excretory urography (EU). This study demonstrated that acute renal failure by grapes and raisins dependent on food dose, and specific characters of individual.

Purification and Identification of Paenibacillus sp., Isolated from Diseased Larvae of Allomyrina dichotoma (Linnaeus, 1771) (Coleoptera: Scarabaeidae) in Insect Farms

  • Kang, Tae Hwa;Han, Sang Hoon;Weon, Hang Yeon;Lee, Young Bo;Kim, Namjung;Nam, Sung Hee;Park, Hae Chul
    • International Journal of Industrial Entomology and Biomaterials
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    • v.25 no.2
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    • pp.195-203
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    • 2012
  • In reared populations of Allomyrina dichotoma, commercial insects, the skin of last instar larvae was changed softer with opaque white, and infested grubs eventually died. To clarify the cause of the symptom, we collected the larvae of A. dichotoma from five farms and examined their intestinal bacterial florae using pyrosequencing technique. From those results, a member of Paenibacillus was found only in the larvae showing the symptom of disease. Through PCR analysis using a Paenibacillus specific primer set, we obtained the partial 16S rRNA gene sequence and confirmed the microbe as Paenibacillus sp. For clear identification, a whole guts was extracted from each larva showing the sign of the disease and incubated at $70^{\circ}C$ for 15 min to isolate spore forming bacteria. After then, each content of guts was cultured on $MYPGP_{NAL}$ agar medium($12.5{\mu}g/ml$ of nalidixic acid) at $30^{\circ}C$. The 16S rRNA gene sequence analysis for the isolated bacteria showed that they were closely related to P. rigui(97.9% similarity), to P. chinjuensis(96.1% similarity), and to P. soli(95.3% similarity). Additional tests including API test and cellular fatty acid composition analysis were performed, but the strain couldn't be identified at species level, suggesting it may represent novel species of the genus Paenibacillus.

Retrospective study of porcine epidemic diarrhea in Korea by in situ hybridization (In situ hybridization에 의한 돼지 유행성 설사증의 국내발생 역추적 진단)

  • Park, Nam-yong;Lee, Seok-yun
    • Korean Journal of Veterinary Research
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    • v.37 no.4
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    • pp.809-816
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    • 1997
  • In this presented study, we established a method for diagnosis of porcine epidemic diarrhea(PED) by in situ hybridization(ISH), which made distinct progress in diagnostic pathology. We also carried out the retrospective diagnosis through ISH to assume the exact time of the first outbreak and incidence of PED in Korea. The outbreak of PED in Korea reported in 1992. However, since the end of 1980's, some researches of pig-industry have already suspected the outbreak of PED, not transmissible gastroenteritis(TGE). In this experiment, we performed the ISH using 80 formalin-fixed and paraffin-embedded tissues of porcine intestine which were requests for pathological diagnosis from 63 farms whose primary sign was diarrhea from 1984 to 1991. We prepared biotinylated cDNA probe(492base pairs) for ISH by nick translation method and carried out the ISH, using $Microprobe^{TM}$ capillary action system(Fisher $Biotech^R$). We detected PED virus in intestinal mucosa of 2 cases in 1992, 1 case in 1988, and 1 case in 1987. As a result, we assume that the outbreak of PED in Korea have already started since 1987.

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A Study on the Correlation between Signs/Symptoms of the Craniomandibular Disorders and Possible Contribution Occlusal Factors (두개하악장애증상발현과 교합요인 사이의 상관성에 관한 연구)

  • Young-O Kim;Keum-Back Shin;Jung-Min Kim
    • Journal of Oral Medicine and Pain
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    • v.18 no.1
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    • pp.31-43
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    • 1993
  • To evaluate the correlationship between sign/symptoms of craniomandibular disorder(CMD) and possible contributing occlusal factors, the author analyzed craniomandibular index(CMI), clinical dysfunction index(CDI) and occlusal index(Oi) obtained from 88 subjects (32 males, 56 females, mean age 28.7) consisted of 49 CMD patients(15 males, 34 females, mean age 28.7) and 39 non-CMD patients (17 males, 22 females, mean age 24.5). The obtained results were as follows : 1. There was very high significant correlation bebween CMI and CDI in total subjects (r=0.83, p<0.01) 2. There was very low correlation between working-side interference and TMJ noise which was observed as a statistically significant value(p<0.05). And also there ws very low correlation between nonworking side interference and muscle tenderness, CDI, dysfunction index(DI), palpation index(PI) which were observed as statistically significant value (p<0.01) 3. There was very low correlation between as ymmetry of tetruded contact position(RCP)-intercuspal position(ICP) slide and muscle tenderness, TMJ tenderness, TMJ noise, CMI, DI, PI which were observed as statistically significant values(p<0.05) 4. In general there was low correlation between Oi and muscle tenderness, CDI, CMI, DI, PI which were observed as statistically significant values (p,0.05). But Oi had a relatively higher correlation with muscle tenderness, PI than whith CDI, DI.

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Pancreatoduodenectomy following neoadjuvant chemotherapy in duodenal adenocarcinoma

  • Dongjin Seo;Bo Gyeom Park;Dawn Jung;Ho Kyoung Hwang;Sung Hyun Kim;Seung Soo Hong;Chang Moo Kang
    • Annals of Hepato-Biliary-Pancreatic Surgery
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    • v.27 no.1
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    • pp.114-119
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    • 2023
  • A 51-year-old male patient had four times of massive hematochezia episode three days before arrival. Carbohydrate antigen (CA) 19-9 level was extremely elevated. Computed tomography, magnetic resonance imaging, and positron emission tomography-computed tomography identified 5.7 cm sized periampullary duodenal cancer with regional metastatic lymph nodes and vascular invasion to aberrant right hepatic artery, main portal vein, and superior mesenteric vein. Diagnosed as duodenal adenocarcinoma through endoscopic biopsy, 16 times of FOLFIRI (5-fluorouracil, leucovorin, irinotecan) was conducted. The regimen changed to XELOX (capecitabine, oxaliplatine), four times of administration was done, and the CA19-9 level dramatically decreased. The tumor decreased to 2.1 cm. After R0 laparoscopic pylorus preserving pancreatoduodenectomy, no adjuvant therapy was given. No sign of recurrence or metastasis was reported, and the patient reached complete remission after five years. We reported a case where neoadjuvant chemotherapy for locally advanced duodenal adenocarcinoma was shown to be effective.

A Study on the Contamination of Solution with Suction used in Tracheostomy Patients (기관지절개술 환자의 흡인시 사용하는 용액의 오염수준 변화 연구)

  • Lim Yun-Hee;Yu Kwang Soo
    • Journal of Korean Public Health Nursing
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    • v.12 no.2
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    • pp.185-200
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    • 1998
  • It has been contributed to public health that the hospital has multiplied in the aspect of number and has been a large size with development of modern medical science, meanwhile the problem of hospital infection is coming out seriously. Respiratory hospital infection among hospital infections develops, very commonly from patients having taken the operation of intubation or tracheostomy, which results from a big factor that the infection developed from medical appliances used for respiration aids, contamination of solution and infection of medical staff. This study is separated into four steps-the time to use normal saline and distillation water for storaging catheter which are the cause of the infection of solution to store distillation water and catheter, not to say the catheter used when the patient who should get tracheostomy operation takes suction. The purpose of this study is to offer the basic data which are needed to check contamination degree as time goes by and nurse intervention and grope for a new nursing intervention. The target of this study is hospitalized 1D an intensive care unit having 700 sickbeds which is located in IKSAN city and it targeted patients before 7 days passed after an operaion of a tracheostormy. Materials collected were analyzed by SPSS PC+ figures program. The result of this study were as follows ; 1. The gradual contamination levels of the normal saline used In suction are showing that colony increase in proportion to the length of time. 2. while colony increases in normal saline with the lapse of time. distillation water mixed with 5cc of potadine did not show any sign of the formation of colony from its preparation until it was used for 8 hours. 3. Such variables as the period of intubation insertion. the length of hospitalization in I.C.U. the age and the level of contamination of normal saline have no inter-relationship. Therefore. as the length of normal saline used In suction. the contamination level increases with the excelleration of the contamination speed. 4. Regarding the number of suction and the contamination level of the normal saline. We can observe correlation contamination level in the 3 step of suction(mean value:13.4) and the saline which was used for one hours(r=0.702. P=0.00l). four hours(r=0.694. P=0.00l). eight hours(r=0.488. P=0.029). Further we can observe contamination in the 4 step of suction (mean value: 17 .8) well as saline used for eight hours; [for one hours (r=0.64l. P=0.002). four hours (r=0.670. P=0.00l). eight hours (r=0.57 4. P=0.008)]. Thesedays clinics use normal saline by changing it. three times a day. however. the timing of saline change and the current suction methoed should be changed given the one hour used normal saline contamination number 79.850. Regarding the number of suction and the contamination lend of the normal saline.

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A study on the relationship between the suicidal attitude and suicidal ideation of College students from the media reports on suicide (자살 관련 보도에 따른 대학생의 자살태도와 자살생각과의 관계)

  • Yang, Hyun Joo;Byun, Eun Kyung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.10
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    • pp.582-590
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    • 2016
  • The purpose of this study is to investigate the relationship between suicidal attitude and suicidal ideation of college students and also to provide the fundamental data in order to strengthen both the standard and the recommendation of media coverage in Korea. A total of 249 college students over the age of 18 years in B city and G do were enrolled for this study. The data were collected between June 9 and July 7 of 2014 and analyzed by using descriptive statistics, t-test, ANOVA, Pearson correlation coefficients, and multiple regression with SPSS 21.0. The mean score of a message of suicidal motivation reports 2 was $51.06{\pm}10.55$, which was the highest. The score of suicidal ideation was $10.41{\pm}12.88$. There were sign&ificant differences in suicidal thought with respect to school system, family income, pocket money, time of physical activity, smoking, and smart-phone usage in university students. It was shown that suicidal thoughts were significantly correlated with message of simple suicidal reports 1(r=.303, p<.001), message of suicidal motivation reports 2(r=.251, p<.001), and message of suicidal mourning man reports 3(r=.225, p<.001). As the suicidal attitude have a close association with reports of suicide, it is necessary that studies on a variety of factors influencing suicidal thoughts of students be repeated.