• 대한한방내과학회지
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• 제45권1호
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• pp.11-30
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• 2024

Objectives: This study evaluated the effects of Ssanghwa-tang (SHT) on lung injury and muscle loss in a COPD mouse model. Methods: C57BL/6 mice were challenged with cigarette smoke extract and lipopolysaccharide, and then treated with two concentrations of SHT (250 and 500 mg/kg). After sacrifice, the bronchoalveolar lavage fluid (BALF) or lung tissue was analyzed by cytospin, ELISA, real-time PCR, flow cytometry analysis, and H&E and Masson's trichrome staining. The grip strength of COPD mice was measured using a grip strength meter. The running time of COPD mice was measured by a treadmill test. Muscle tissue of the quadriceps was stained with H&E and Masson's trichrome staining. Results: SHT significantly inhibited the increase in neutrophil numbers in BALF and significantly decreased immune cell activity in BALF and lung tissue. It also significantly inhibited the increase in TNF-α, IL-17, and MIP2 in BALF. Real-time PCR analysis revealed that the mRNA expression of TNF-α, IL-17, MIP2, and TRPV1 in lung tissue showed a significant decrease compared with the control group. Lung tissue damage was significantly reduced in the histological analysis. The grip strength and running time of the COPD mice showed a significant decrease compared with the control group. In histological staining, SHT was found to reduce the damage to muscle tissue. Conclusions: This study indicates that SHT can be used as a therapeutic agent for COPD patients by inhibiting lung injury and muscle loss.

• 동의생리병리학회지
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• 제26권4호
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• pp.446-454
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• 2012

In order to evaluate the efficacy of SHT against atopic dermatitis (AD), various immune related cytokines as well as histological comparison were performed in animal models, and the results are described. Clinical skin index of the SHT treated group decreased significantly in weeks 11 and 13, compared to the control group. Also, CD4+ immune cell ratio in the dorsal skin was significantly decreased to 69%, and both epidermal and dermal skin thickness was decreased. Serum IL-4, IL-5, IL-6, IL-13, and TNF-${\alpha}$, which are all important markers of inflammation, were decreased to 64%, 44%, 87%, 48%, and 45%, respectively. The expression of histamine, a chemical transmitter increasingly released during the progression of inflammation, was significantly decreased to 47%. The production of IgE immunoglobulin was significantly decreased to 16% compared to the control group. In conclusion, SHT pacifies the activation of T cells, leading to suppression of both Th2 cytokine overexpression and infiltration of immune cells into skin. As a result, relative thinning of both epidermis and dermis were observed. With the results obtained from in vitro studies, the immune modulatory effect of SHT in AD animal models was experimentally demonstrated. This study should provide solid information to construct EBM and for clinical practice.

• 한국컴퓨터정보학회논문지
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• 제16권1호
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• pp.47-52
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• 2011

본 논문은 수면을 이루는 침실의 수면 환경 데이터를 수집하고, 얻어진 조건 데이터들과 수면간의 관계를 분석한다. 이를 바탕으로 시뮬레이션 모델을 추출하여 개개인에 따른 최적의 수면 환경을 제공하도록 한다. 실험은 H-MOTE2420 센서의 온/습도 센서(SHT11)와 조도 센서(GL5507)를 이용하였다. 뒤척임 추출을 위하여 비디오에서 움직임을 추출하는 차영상 기법을 이용하였다. 또한, 수면에 영향을 미칠만한 가중치의 정보로 피로도, 음주도, 공복도 등의 정보를 입력 받는다. 실험 결과 최적의 수면 환경을 추출할 수 있었다. 향후에는, 수면의 특정 상황만 아니라 식사, 출근 등과 같은 유기적인 유비쿼터스 생활환경의 한 부분에도 상황에 따른 적절한 실내 환경 변화를 제공 해주어서 좀 더 쾌적한 일상생활을 영위할 수 있도록 도움을 주도록 개선하려 할 것이다.

• 지역사회간호학회지
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• 제1권1호
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• pp.465-502
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• 1989

The purpose of this study was to find out the general characteristics of school health teachers, the status of school health resources and the degrees of self-confident performance for the 124 school health teachers in Pusan City. Data was collected by means of questionaires from Aug. 1986 to Mar. 1987. The data were analyzed by use of percentage, mean, standard deviation, t-test, ANOVA and Pearson-correlation coefficient. The results of this study were as follows: 1 . General Characteristics of School Health Teachers (SHT) 1) The average of age of the SHT was 32.8 years old and 39.5% of them were from 30 to 34 years old. 2) The average for school nursing experience of the SHT was 7.9 years and 37.9% of them were from 5 to 9 years. 3) The 45.2% of them have not the clinical experience. 4) The 74.2% of them were graduated from the 3 years college of nursing. 2. Status of school health resources and nursing activities. 1) The average of student number was 2497.3 and class number was 45.2. 2) The average of school health budget was 1039000 won and 27.7% of school health budget expended on examination cost. 3) Only 29.0% of all schools have organization for school health. 4) The 84.7% of all schools have health clinic separately and 69.1% of schools have less than $33m^2$ sized. 5) The average of clinic visitor number was 2111.8 for 1 year. 6) Major problem was on digestive system. And other problems were skin, respiratory, musculo-skeletal system and dental problem. 7) The number of literal message was 14.4 times for 1 year. 3. The degree of the school health teachers' self-confidence. The school health teachers' self-confidence was deviced into 6 and the maximum degree was 4. 1) Program planning & evaluation; 2.8 2) Clinic management; 2.9 3) Health education, 3.0 4) Management of school environment; 2.7 5) Health care services; 2.7 6) Operating of school health organization; 2.4 4. Significances to the degree of self-confidence on school health nursing activities. 1) There was significant difference between clinical management and Religion (t=2.15 p<.05) 2) There was significant difference between Operating of school health organization and level of school (F=3.588 p<.05) 3) Program planning & evaluation: expending time for clinical management (r=-0.184 p<.05) expending time for health care services (r=0.273 p<.01) 4) Clinical management: use of separate health clinic (r=0.151 p<.05) 5) Health education: use of separate health clinic (r=0.170 p<0.5) 6) Health care services: No. of student (r=-0.144 p<0.5) No. of class (r=-0.160 p<.05) 5. The degree of the school health teachers' self-discipline. The school health teachers' self-discipline was devided into 2 and the maximum degree was 2. 1) Program planning & evaluation:1.8 2) Clinic management: 1.9 3) Health education: 1.9 4) Management of school environment: 1.7 5) Health care services: 1.8 6) Operating of school health organization.: 1.3 6. Significances to the degree of self-discipline on school health nursing activities 1) Program planning & evaluation; Level of nursing education (F=4.309 p<.01) 2) Clinical management: Level of nursing education (F=3.587 p<.05) 3) Operating of school health organization: School health organization (t=-2.68 p<.01) 4) Health care services: School health organization (t=2,58 p<.05) 5) School health performance: School health organization (t=2.32 p<.05) 6) Program planning & evaluation: School health experience (r=0.239 p<.01) Expending time for program planning & evaluation (r=-0.172 p<.05) 7) Clinic management: School health experience (r=0.249 p<.01) Expending time for dinic management (r=0.181 p<.05) No. of student (r=-0.158 p<.05) Expending time of program planning & evaluation (r=-0.199 p<0.5) 8) Health education: School health experience (r=0.234 p<0.1) Expending time of program planning & evaluation (r=-0.193 p<.05) 9) Management of school environment: Age of school health teacher (r=0.142 p<.05) School health experience (r=0.255 p<.01) 10) Operating of school health organization: Medicine Purchase (r=-0.163 p<.05) 11) Health care services: School health experience (r=0.148 p<.05) Medicine purchase (r=-0.229 p<.01) 12) Total school health performance: School health experience (r=0.200 p<.05) Medicine purchase(r=-0.168 p<.05) Based on the above results, the suggestions are as follows: 1) As the SHT take charge of the reasonable number of student, the students will have benefit of the good health service in quality. 2) It is recommended to use the health clinic separately and to arrange adequate place for good school health service. 3) It is necessary that the SHT participate budget for school health. 4) It is required to enhance self-confidence on school health nursing activities through continuous educational programs.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
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• pp.11-11
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• 1993

The Korean sounding rockets(KSR) 1, 2 equigped with the UV optical detectors have been launched at An-heung, Chungchongnam-do, of June 4 and September 1, 1993,respectively. The UV detector is used to measure the attenuation of solar UV radiation for various frequency bards in the stratospgere. We obtained the profile of the ozone number density within the altitulde of 15 - 30 km by applying the Beer-Lambert law. It is found that the maHimum of the ozone distribution occurs near 2sht which is quite consistent with the mean value in the mid-latituderegions. We will also compare our results froiu KSR 1,2 with the other observational data from the Dobson speceo meter at Yonsei Univ. and the LIDAa which were performed simultaneously with the sounding rocket experiments.

• 한국정보통신학회논문지
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• 제13권3호
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• pp.623-628
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• 2009

최근 정보화를 기반으로 급변하는 사회 현상과 함께 관심을 끌고 있는 USN프로젝트는 아직까지 미흡한 점들이 많이 존재하고 있는 상황이다. 현재의 연구 진행은 정보이용의 효율성을 추구하는 움직임이 주를 이루고 있으며, 네트워크 기술과 나노기술의 발달 등으로 인하여 USN 시장의 확대와 활성화에 많은 영향을 끼치고 있다. 우리나라의 경우 USN 구축 계획의 시행과 급변하는 네트워크 시장 등의 영향으로 수많은 연구가 진행되고 있으며, 무선센서를 이용한 분야의 확대 움직임이 활성화되고 있다. 본 논문에서는 우리나라의 USN 프로젝트의 기반이 되는 센서 네트워크에 대한 연구를 위하여 일반적으로 구성 가능한 센서노드, 싱크노드와 임베디드 시스템을 이용한 무선 센서 네트워크의 모델을 설계하고 ST사의 STR711FR2 프로세서 칩과 Sensirion사의 SHT11센서 모듈 그리고 Chipcon사의 CC2420 통신모듈을 사용하여 센서 노드를 설계하였다. 이후 제작된 센서노드에 임베디드 시스템을 이용하여 목적에 맞는 프로그램을 탑재하고 이를 이용하여 센서네트워크를 구현하였으며, 센서노드와 호스트 PC간의 데이터 전송실험을 위하여 센서로부터 센싱된 온도와 습도 데이터의 전송실험을 하였다.

• 한국패류학회지
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• 제17권2호
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• pp.71-78
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• 2001

1995년 4월부터 1996년 3월까지 충청남도 보령시 연안에 서식하는 키조개를 총 701마리 채집하여 성장을 조사하였다. 1. 키조개의 패각에 나타나는 윤문은 년1회 형성되며 주 윤문형성시기는 6월에서 7월로 조사되었다. 2. 초륜 형성기간은 12개월(만 1년)로 나타났다. 3. 각고 (SH)와 총중량 (TW)간의 관계는 TW=5.906$\times$$10^{-3}$S $H^{3.3844}$이었으며, 각장 (SL)과 각고(SH)간의 관계는SL=0.5277SH+0.0934이고, 각장 (SL)과 각폭(SW)간의 관계는 SW=0.2681SH-1.3757였다. 4. 연령(t)에 대한 각고 (SH)와 총중량 (TW)의 Bertalanffy 성장식은 SHt=30.99(1-e-$^{0.321}$2(t+0.9653)/이고 (Fig.11) TWt=657.94(1-e-$^{0.321}$2(t+0.9653/)$^{3.3844}$(Fig. 12)였다.)였다.