• Journal of Acupuncture Research
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• v.36 no.2
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• pp.92-99
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• 2019

Background: This study was conducted to evaluate the effects of pharmacopuncture and dermal application of Sebalgukhwa-san extracts on hair growth in an alopecia mouse model. Methods: Twenty-one C57BL/6 mice were divided into 3 groups; control group-normal saline injection or vehicle solution application, positive control group-minoxidil (MNXD), experimental group-pharmacopuncture and applied Sebalgukhwa-san (SGS) extract. The effects of the treatment on hair growth, were determined through photographs, and phototrichogram analysis by folliscope. Hair follicle morphometry by hematoxylin-eosin staining was performed, and hair growth-related protein expression of vascular endothelial growth factor, insulin like growth factor-1, and transforming growth factor-beta 1 were monitored by Western blotting. Serum levels of aspartate aminotransferase and alanine aminotransferase were measured for liver function test. Results: Body weight increased consistently in all groups. Hair growth was improved in the MNXD and SGS groups compared with the control. Hair density and thickness improved statistically significantly in the MNXD and SGS groups compared with the control p < 0.05. The number of hair follicles improved in the MNXD and SGS groups compared with the control but the size did not. The expression of vascular endothelial growth factor and insulin like growth factor-1 increased, and there was a decrease in the expression of transforming growth factor-beta 1 in the MNXD and SGS groups compared with the control, however, there was no significant difference. Sebalgukhwa-san treatment had no toxicity in liver function tests. Conclusion: Pharmacopuncture and dermal application of Sebalgukhwa-san extract may be therapeutically beneficial for the treatment of alopecia.

• Atmosphere
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• v.34 no.2
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• pp.153-176
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• 2024

At 0843 UTC 30 May 2021, a commercial aircraft encountered severe turbulence at z = 11.5 km associated with the rapid development of Mesoscale Convective System (MCS) in the Gyeonggi Bay of Korea. To investigate the generation mechanisms of Near-Cloud Turbulence (NCT) near the MCS, Weather Research and Forecasting model was used to reproduce key features at multiple-scales with four nested domains (the finest ∆x = 0.2 km) and 112 hybrid vertical layers. Simulated subgrid-scale turbulent kinetic energy (SGS TKE) was located in three different regions of the MCS. First, the simulated NCT with non-zero SGS TKE at z = 11.5 km at 0835 UTC was collocated with the reported NCT. Cloud-induced flow deformation and entrainment process on the downstream of the overshooting top triggered convective instability and subsequent SGS TKE. Second, at z = 16.5 km at 0820 UTC, the localized SGS TKE was found 4 km above the overshooting cloud top. It was attributed to breaking down of vertically propagating convectively-induced gravity wave at background critical level. Lastly, SGS TKE was simulated at z = 11.5 km at 0930 UTC during the dissipating stage of MCS. Upper-level anticyclonic outflow of MCS intensified the environmental westerlies, developing strong vertical wind shear on the northeastern quadrant of the dissipating MCS. Three different generation mechanisms suggest the avoidance guidance for the possible NCT events near the entire period of the MCS in the heavy air traffic area around Incheon International Airport in Korea.

• International Journal of Aeronautical and Space Sciences
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• v.14 no.2
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• pp.112-121
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• 2013

An approach for composing a performance optimized computational code is suggested for the latest microprocessors. The concept of the code optimization, termed localization, is maximizing the utilization of the second level cache that is common to all the latest computer systems, and minimizing the access to system main memory. In this study, the localized optimization of the LU-SGS (Lower-Upper Symmetric Gauss-Seidel) code for the solution of fluid dynamic equations was carried out in three different levels and tested for several different microprocessor architectures widely used these days. The test results of localized optimization showed a remarkable performance gain of more than two times faster solution than the baseline algorithm for producing exactly the same solution on the same computer system.

• 한국전산유체공학회:학술대회논문집
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• 2001.05a
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• pp.45-50
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• 2001

An approach of composing a performance optimized computational code is suggested for latest microprocessors. The approach named as localization is a concept of minimizing the access to system's main memory and maximizing the utilization of second level cache that is common to all the latest computer system. The localized compositions of LU-SGS scheme for fluid dynamics were made in three different levels and tested on three different microprocessor architectures most widely used in these days. The test results of localization concept showed a remarkable performance, that is the showing gain up to 4.5 times faster solution than the baseline algorithm $450\%$ for producing an exactly the same solution.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.23 no.1
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• pp.82-91
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• 1999

A numerical analysis based on the three-dimensional Reynolds-averaged Navier-Stokes equation has been conducted to investigate the flow within a NASA rotor 67 transonic fan. General coordinate transformations are used to represent the complex blade geometry and an H-type grid is used. The governing equations are solved using implicit LU-SGS scheme for the time-marching integration and a standard ${\kappa}-{\varepsilon}$ model is used with wall functions for the turbulence modeling. The computations are compared with the experimental data and a detailed study of the flow structures near peak efficiency and near stall is presented. The calculated overall aerodynamic efficiency and three-dimensional shock system agree well with the laser anemometer data.

• Journal of Internet Computing and Services
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• v.18 no.6
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• pp.7-13
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• 2017

In this paper, we propose a novel dynamic subchannel grouping (DSG) algorithm to maximize the system capacity considering intended proper outage probability for the downlink of enterprise small-cell networks (ESNs). In the proposed DSG scheme, a local gateway (LGW) which is installed in a building dynamically divides the frequency bandwidth into different numbers of subchannel groups (SGs) based on the numbers of small-cell access points (SAPs) and small-cell user equipments (SUEs) per floor. Then, the LGW assigns the SGs to SAPs and the SAPs allocate them to their serving SUEs. Through simulation results, we show that the proposed DSG scheme is appropriate for the ESNs compared to the conventional small-cell networks in which all SAPs use the number of fixed SGs in terms of the system capacity and outage probability.

• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.1136-1139
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• 2009

Recently, various Ni doping systems and thermal annealing systems have been developed for fabrication of polycrystalline silicon film using SGS (super grain silicon) for medium and largesize AMOLED panels. In this study, we compare the potential of Ni doping systems including ALD (atomic layer deposition), AMD (atmospheric metal deposition), in-line sputter, and crystallization annealing systems including batch type furnace, inline furnace, and RTA (rapid thermal annealing) developed for the SGS method. Additional requirements for those systems to be used for mass production of large AMOLED TVs are suggested based on evaluation results for both poly-Si films and TFT backplanes.

• Journal of Aquaculture
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• v.17 no.1
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• pp.39-45
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• 2004

Three experiments were conducted to determine utilization of Song-Gang(equation omitted) stone as the dietary additive for growth and immune stimulant in juvenile olive flounder. In the feeding trial, four diets were formulated to contain 0, 0.5, 1.0 and 2.0% Song-Gang(equation omitted) stone per kg diet (SGS$_{0}$ , SGS$_{0.5}$, SGS$_{1.0}$ , SGS$_{2.0}$ ). Fish averaging 5.0$\pm$0.04 g (mean$\pm$SD) were fed one of four experimental diets in triplicate groups for 8 weeks. There were no significant differences in weight gain, feed efficiency, protein efficiency ratio, hematosomatic index, condition factor and survival among fish fed all the diets. In chanlenge test, fish were infected by intraperitoneal injection of 0.1 $m\ell$ bacterial suspension with Edwardsielia tarda per fish after the feeding trial. Fish fed SGS$_{0.5}$ diet have a significantly higher cumulative survival rate than did fish fed the other diets (P<0.05). In the anti-mold test, Asprrgiilus niger, Penicillium pinophiltfm, Chaeromium globosum were inoculated with Song-Gang(equation omitted) stone using ASTM G-21 method. The amount of Α. niger, Ρ. pinuphiium. C. globosum didn't increase in Song-Gang(equation omitted) stone for 4 weeks for the test period. Therefore, these results indicate that 0.5% Song-Gang(equation omitted) stone per kg diet could increase immune resistance in juvenile olive flounder and Song-Gang(equation omitted) stone could be used as the anti-mold additive in fish feed.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.31 no.1
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• pp.19-26
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• 2020

Background and Objective Endoscopic airway dilation is the primary treatment for pediatric subglottic stenosis (SGS) due to its feasibility and non-invasiveness. The aim of this study is to evaluate the risk factors for the failure of endoscopic airway dilation in pediatric patients with SGS. Materials and Methods This study reviewed medical records of 38 pediatric patients had endoscopic dilation from a single and tertiary referral center, retrospectively. The success of the endoscopic dilation procedure was defined as no dyspneic symptom without tracheostomy or laryngotracheal reconstruction. Demographic profiles, underlying disease, and Myer-Cotton SGS severity grade were recorded. Success rates and risk factors for the failure of treatment were analyzed. Results The SGS patients with severity grade I was most common. After mean 1.8 numbers of procedures, there were 23 patients (60.5%) in the success group and 15 patients (39.5%) in the failure group. Age, sex, underlying diseases, and SGS severity grade were not significantly different between two groups. In patients who had multiple endoscopic procedures, the failure group showed SGS deteriorated after procedures in 66.7%, compared to 11.1% of the success group. In multivariable analysis, a long-term intubation (≥1 month) was identified as an independent risk factor for failure of endoscopic dilation procedure. Conclusion Although endoscopic dilation procedure is safe and effective for the management, repetitive endoscopic dilation may not give clinical benefit in patient with long-term intubation. Other airway procedures must be considered in those group of patients.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 1993.06a
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• pp.1037-1040
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• 1993

In this paper a fuzzy controller for a flexible arm with one degree of freedom is presented. Goal of the control is to drive the manipulator to the position $\theta$0 avoiding the oscillations due the elasticity of the arm. The performances of the fuzzy controller are evaluated through a series of simulations that shows appreciable results both for the transient and the steady behaviour.