• Title/Summary/Keyword: SGCS

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Store-operated calcium entry in the satellite glial cells of rat sympathetic ganglia

  • Sohyun Kim;Seong Jun Kang;Huu Son Nguyen;Seong-Woo Jeong
    • The Korean Journal of Physiology and Pharmacology
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    • v.28 no.1
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    • pp.93-103
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    • 2024
  • Satellite glial cells (SGCs), a major type of glial cell in the autonomic ganglia, closely envelop the cell body and even the synaptic regions of a single neuron with a very narrow gap. This structurally unique organization suggests that autonomic neurons and SGCs may communicate reciprocally. Glial Ca2+ signaling is critical for controlling neural activity. Here, for the first time we identified the machinery of store-operated Ca2+ entry (SOCE) which is critical for cellular Ca2+ homeostasis in rat sympathetic ganglia under normal and pathological states. Quantitative realtime PCR and immunostaining analyses showed that Orai1 and stromal interaction molecules 1 (STIM1) proteins are the primary components of SOCE machinery in the sympathetic ganglia. When the internal Ca2+ stores were depleted in the absence of extracellular Ca2+, the number of plasmalemmal Orai1 puncta was increased in neurons and SGCs, suggesting activation of the Ca2+ entry channels. Intracellular Ca2+ imaging revealed that SOCE was present in SGCs and neurons; however, the magnitude of SOCE was much larger in the SGCs than in the neurons. The SOCE was significantly suppressed by GSK7975A, a selective Orai1 blocker, and Pyr6, a SOCE blocker. Lipopolysaccharide (LPS) upregulated the glial fibrillary acidic protein and Toll-like receptor 4 in the sympathetic ganglia. Importantly, LPS attenuated SOCE via downregulating Orai1 and STIM1 expression. In conclusion, sympathetic SGCs functionally express the SOCE machinery, which is indispensable for intracellular Ca2+ signaling. The SOCE is highly susceptible to inflammation, which may affect sympathetic neuronal activity and thereby autonomic output.

Design of the COMS Satellite Ground Control System (통신해양기상위성 관제시스템 설계)

  • Lee, Byeong-Seon;Jeong, Won-Chan;Lee, Sang-Uk;Lee, Jeom-Hun;Kim, Jae-Hun
    • Journal of Satellite, Information and Communications
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    • v.1 no.2
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    • pp.16-24
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    • 2006
  • As a multi-mission GEO satellite, COMS system is being developed jointly by KARI, ETRI, KORDI, KMA, and industries from both abroad and domestic. EADS ASRTIUM is the prime contractor for manufacturing the COMS. ETRI is developing the COMS Ka-band payload and SGCS with the fund from MIC. COMS Satellite Ground Control System (SGCS) will be the only system for monitor and control of the satellite in orbit. In order to fulfill the mission operations of the three payloads and spacecraft bus, COMS SGCS performs telemetry reception and processing, satellite tracking and ranging, command generation and transmission, satellite mission planning, flight dynamics operations, and satellite simulation, By the proper functional allocations, COMS SGCS is divided into five subsystems such as TTC, ROS, MPS, FDS, and CSS. In this paper, functional design of the COMS SGCS is described as five subsystems and the interfaces among the subsystems.

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A PROPOSED HIGH AVAILABILITY ARCHITECTURE FOR COMS GROUND CONTROL SYSTEM

  • Kim In-Jun;Kim Jae-Hoon
    • Bulletin of the Korean Space Science Society
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    • 2004.10b
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    • pp.266-269
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    • 2004
  • A satellite ground control system (SGCS) which monitors and controls a geostationary satellite 24 hours a day has to achieve the system architecture assuring high-level availability and redundancy scheme. The SGCS for Communication, Ocean, and Meteorological Satellite (COMS) is currently being developed in Korea, which will be implemented to satisfy high availability (HA), expansibility, and compatibility in design. In order to implement the system architecture to meet these characteristics, the SGCS for COMS introduces the concept of the real-time distributed system structure based on redundancy scheme for high availability, data replication and sharing, and CORBA middleware.

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Low-Power Design of the Surface Gradient Coil for Magnetic Resonance Imaging (자기공명영상촬영을 위한 표면경사자계코일의 저전력 설계)

  • Oh, Chang-Hyun;Lee, Jong-Kwon;Yi, Yun;Kim, Min-Gi
    • Proceedings of the KOSOMBE Conference
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    • v.1993 no.11
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    • pp.33-35
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    • 1993
  • A new low-power, high-order optimization scheme to design surface gradient coils (SGC) is proposed for magnetic resonance imaging (MRI). Although previous SGCs have been designed and constructed just to get strong linear gradients, this paper proposes more systematic ways of SGC design by minimizing electrical power consumption in the gradient coil and by removing unnecessary high-order field distortions in the imaging region. By assuming continuous current flow on the coil surface which may be or may not be planar, power consumption in the coil is minimized. According to the simulation results, the SGC designed by using the proposed scheme seems to produce much more uniform linear gradient field using less electrical power compared to the previously proposed SGCs.

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Operational Validation of the COMS Satellite Ground Control System during the First Three Months of In-Orbit Test Operations (발사 후 3개월간의 궤도 내 시험을 통한 통신해양기상위성 관제시스템의 운용검증)

  • Lee, Byoung-Sun;Kim, In-Jun;Lee, Soo-Jeon;Hwang, Yoo-La;Jung, Won-Chan;Kim, Jae-Hoon;Kim, Hae-Yeon;Lee, Hoon-Hee;Lee, Sang-Cherl;Cho, Young-Min;Kim, Bang-Yeop
    • Journal of Satellite, Information and Communications
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    • v.6 no.1
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    • pp.37-44
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    • 2011
  • COMS(Chollian) satellite which was launched on June 26, 2010 has three payloads for Ka-band communications, geostationary ocean color imaging and meteorological imaging. In order to make efficient use of the geostationary satellite, a concept of mission operations has been considered from the beginning of the satellite ground control system development. COMS satellite mission operations are classified by daily, weekly, monthly, and seasonal operations. Daily satellite operations include mission planning, command planning and transmission, telemetry processing and analysis, ranging and orbit determination, ephemeris and event prediction, and wheel off-loading set point parameter calculation. As a weekly operation, North-South station keeping maneuver and East-West station keeping maneuver should be performed on Tuesday and Thursday, respectively. Spacecraft oscillator updating parameter should be calculated and uploaded once a month. Eclipse operations should be performed during a vernal equinox and autumnal equinox season. In this paper, operational validations of the major functions in COMS SGCS are presented for the first three month of in-orbit test operations. All of the major functions have been successfully verified and the COMS SGCS will be used for the mission operations of the COMS satellite for 7 years of mission life time and even more.

High-Order Surface Gradient Coil Design Using Target Field Approach

  • Lee, J.K.;Yang, Y.J.;Jeong, S.T.;Choi, H.J.;Cho, Z.H.;Oh, C.H.
    • Journal of Biomedical Engineering Research
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    • v.17 no.1
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    • pp.19-24
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    • 1996
  • The purpose of this paper is to design high-order (or radial) surface gradient coil (SGC), which can provide multi-dimensional spatial selection. Although the spatial Selection with High-Order gradienT (SHOT) can provide a 2-D selection with only one selective RF pulse, the high-order gradient pro- duced by conventional cylindrical-shape coils has not been clinically useful due to the large selection size caused by the limited radial gradient intensity. However, by using the proposed high-order SGCs located near the imaging region, the size of volume selection can be reduced to a clinically useflll size of 1-2 cm in diameter by applying stronger radial gradient field with much less gradient driving power. So far radial SGCs have been designed by using the field component method and may cause distortion in the selection shapes. In this paper, by using the target field approach for the coil design, selected volumes became almost circular. A 40 cm-by-40 cm $z^2$_surface gradient coil has been designed and implemented by using the target field approach. Phantom and volunteer studies have been performed Experimental results using spatially localized MRI show good agreement to the theoretically predicted behavior.

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A New Spatial Localization Technique Using High-Order Surface Gradient Coils (SGC) (고차표면 경사자계코일을 이용한 새로운 공간 선택 방법)

  • Lee, J.K.;Yang, Y.J.;Jeong, S.T.;Yi, Y.;Cho, Z.H.;Oh, C.H.
    • Proceedings of the KOSOMBE Conference
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    • v.1994 no.12
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    • pp.43-46
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    • 1994
  • A new spatial localization technique using high-order surface gradient coil (SGC) is proposed. Although the Spatial Selection with High-Order gradient (SHOT) can provide a 2-D selection with only one selective RF pulse, the high-order gradient produced by cylindrical-shape coils has not been clinically useful for clinical systems due to the large minimum selection size caused by the limited radial gradient intensity. However, by using the proposed high-order SGCs located near the imaging region, the size of volume selection can be reduced to a clinically useful 1-4 cm in diameter by applying stronger radial gradient with much less gradient driving power. A 40 cm-by-40 cm $r^{2}$ SGC has been designed and constructed, and phantom and volunteer studies have been performed. Experimental results using spatially localized MRI show good agreement to the theoretically predicted behavior.

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JPEG Performance analysis for COMS LHGS Design (통신해양 기상위성 LHGS 설계를 위한 JPEG 성능 분석)

  • Bae Hee-Jin;Seo Seok-Bae;Ahn Sang-Il;Jung Sung-Chul;Kim Eun-Kyou
    • Proceedings of the KSRS Conference
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    • 2006.03a
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    • pp.381-385
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    • 2006
  • 2008년 발사를 목표로 개발되고 있는 통신해양기상위성(COMS: Communication, Ocean and Meteorological Satellite)는 기상 관측과 해양 관측 임무 및 통신 임무까지 수행하는 정지궤도 위성이다. 통신해양기상위성은 크게 탑재체와 지상국으로 나눌 수 있고 지상국은 다시 통신 임무를 위한 CTES(Communication Test Earth Station), 해양/기상 임무를 위한 IDACS(Image Acquisition and Control System), 그리고 위성 관제와 운영을 위한 SGCS(Satellite Ground Control System)로 구분된다. 이 중 IDACS의 서브시스템 중 하나인 LHGS(LRIT/HRIT Generation Subsystem)는 LRIT/HRIT(Low Rate Information Transmission/High Rate Information Transmission)를 생성하고 배포하는 기능을 가지고 있다. 관측 종료 후 LRIT/HRIT 전송 완료까지 15분 이내로 이루어져야 한다는 기상청의 요구사항을 만족하기 위해서 JPEG 압축 시간도 중요한 요소로 고려되어야 한다. 그래서 본 논문에서는 MTSAT에서 받은 LRIT/HRIT의 자료 처리를 바탕으로 lossless JPEG와 lossy JPEG의 압축 시간을 측정하여 압축률을 비교하여 성능 분석을 해보기로 한다. 이렇게 도출해낸 수치자료는 COMS LHGS 설계에 활용할 수 있다.

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Chain orientation and Degradation Behavior of Poly[(R)-3-hydroxybutyrate] Lamellar Crystals

  • Lee, Won Gi;Jo, Nam Ju;Ha, Chang Sik
    • Bulletin of the Korean Chemical Society
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    • v.22 no.8
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    • pp.872-876
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    • 2001
  • Topological changes caused by the alkaline and enzymatic attacks of solution-grown, chain-folded lamellar crystals (SGCs) of poly[(R)-3-hydroxybutyrate] P(3HB) have been studied in order to investigate the chain-folding structure in P(3HB) crystal regions. NaOH and an extracellular PHB depolymerase purified from Alcaligenes faecalis T1 were used for alkaline and enzymatic hydrolysis, respectively. The measurements were performed on crystals attached to a substrate which is inactive to degradation mediums. Both alkaline and enzymatic attacks lead to a breakup of the lamellar crystals along the crystallographic b-axis during initial erosion. Since hydrolysis preferentially occurs in amorphous regions, this morphological result reflects relatively loosely packed chains in core parts of lamellar crystals. Additionally, it was supported by the ridge formation along the b-axis in the lamellar crystals after thermal treatment at a low temperature because of the thermally sensitive nature of the loosely packed chains in lamellar crystals. However, the alkaline hydrolysis accompanied the chain erosions or scissions in quasi-regular folded lamellar surfaces due to smaller size of alkaline ions in comparison to the enzyme, resulting in the decrease of molecular weight.

Design of RF Supporting Unit for COMS RF Compatibility Test (COMS RF호환성 시험을 위한 RF지원 장비의 설계 및 제작)

  • Park, Durk-Jong;Park, Chun-Woo;Ahn, Sang-Il
    • Aerospace Engineering and Technology
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    • v.7 no.2
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    • pp.176-186
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    • 2008
  • As determined single coaxial cable for the interface between satellite and ground station in COMS RF compatibility test, RF supporting unit was required to allow signals in different frequency-band to be exchanged in the single coaxial cable. In addition, the path loss between satellite and ground station in normal operation should be simulated through two RF supporting units connected to the ends of single coaxial cable. As an effort to design RF supporting unit, level diagram was firstly conducted on the basis of measured data for each element. From the level diagram, it was found that single coaxial cable connected with two RF supporting units properly represented the path loss between satellite and ground station After RF supporting unit was integrated on aluminum plate, it was tested that input signal level at each test cap linked with MODCS and TC&R was tunable within the required dynamic range. RF supporting unit, now completely integrated, will be applied in the upcoming COMS RF compatibility test.

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