• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.21 no.3
• /
• pp.69-81
• /
• 2008

Objective : The purpose of this study was find out the anti-allergic effects of SESHINGO on the allergic rhinitis. Methods : Cell viability was evaluated by the MTT assay. Cells were treated with the indicated concentration of SSG. $TNF-\alpha$ concentration was measured from cell supernatants using ELISA method. IL-4 concentration was measured from cell supernatants using ELISA method.$IFN-\gamma$ concentration was measured from cell supernatants using ELISA method. Total RNA was isolated, $TNF-\alpha$ and IL-4 mRNA expression was detected by RT-PCR analysis Total RNA was isolated, COX-1, COX-2 mRNA was analyzed by RT-PCR analysis. Results : 1. $\beta$-hexosaminidase release in RBL-2H3 cells were decresed by SESHINGO attentively. 2. Secreting ration of $TNF-\alpha$was restrained in RBL-2H3 cells by SESHINGO attentively. 3. Secreting ration of IL-4 was restrained in RBL-2H3 cells by SESHINGO attentively 4. Revelation of $TNF-\alpha$ mRNA was decresed in RBL-2H3 cells as concetration. 5. Revelation of.IL-4 mRNA was decresed in RBL-2H3 cells as concetration. 6. Revelation of COX-2 mRNA was decresed in RBL-2H3 cells. Conclusion : According to above results, to evaluate the effect of SSG on the anti-allergic effects.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.14 no.1
• /
• pp.11-31
• /
• 2001

1. Rhinocleisis: In the frequency of prescription of internal therapy, tongkyutang, bangpungtongsungsan, shinisan and yeotaektongkitang are often used. In the frequency of herb of internal therapy, baekgi(白芷), bangpung(防風), kanghwal(羌活), chungung(川芎) and seuma(升麻) are often used. In the frequency of prescription of external therapy, changposan is often used. In the frequency of herb of external therapy, sesin(細辛), tongcho(通草), chungung(川芎), buza(附子) and koache(瓜薺) are often used. 2. Watery Rhinorrhea : In the frequency of prescription of internal therapy, tongkyutang, seshinsan and chunchosan are often used. In the frequency of herb of internal therapy, chungung(川芎), seshin(細辛) and bangpung(防風) are often used. In the frequency of prescription of external therapy, seshingo is often used. In the frequency of herb of external therapy, seshin(細辛), chuncho(川椒) and bangpung(防風) are often used. 3. Viscous Rhinorrhea : In the frequency of prescription of internal therapy, bangpungtang, changisan and shinisan are often used. In the frequency of herb of internal therapy, chungung(川芎), bangpung(防風), bakha(薄荷) and hwangeum(黃芩) are often used. 4. Anosmia : In the frequency of prescription of internal therapy, yeotaektongkitang is often used. In the frequency of herb of internal therapy, bangpung(防風), baegi(白芷) and kangwhal(羌活) are often used. 5. Nasal Polyp: In the frequency of prescription of internal therapy, yangpesan is often used. In the frequency of herb of internal therapy, baekchul(白朮), kunkang(乾薑) and hwangkeum(黃芩) are often used. In the frequency of prescription of external therapy, shinigo, tongchosan and baekhwangsan are often used. In the frequency of herb of external therapy, seshin(細辛), koache(瓜薺) and woonghwang(雄黃) are often used. 6. Epistaxis : In the frequency of prescription of internal therapy, sanggihwangtang is often used. In the frequency of herb of internal therapy, sanggihwang(生地黃), hwanggeum(黃芩) and jakyak(芍藥) are often used. 7. Rhinophyma : In the frequency of prescription of internal therapy, hyunggasan and chunghyulsamultang are often used. In the frequency of herb of internal therapy, danggui(當歸), hwanggeum(黃芩) and chija(梔子) are often used. In the frequency of prescription of external therapy, baekbansan is often used. In the frequency of herb of external therapy, yoohwang(硫黃), kyungbun(輕粉) and hangin(杏仁) are often used.