• Science of Emotion and Sensibility
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• v.22 no.4
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• pp.57-64
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• 2019

Anger is the most common emotional trigger causing relapses in individuals with alcohol use disorders (AUDs). The present study intended to investigate the autonomic nervous system (ANS) responses induced by anger in individuals with AUDs. The participants in this study included twelve individuals with AUDs and 14 non-frequent drinkers. Anger was induced in the participants via a 120-second film clip. Before the presentation of this audio-visual stimulus, the ANS responses of the participants were measured for 60 seconds to ascertain their resting state. Subsequently, the participants' ANS responses were measured again for 120 seconds when they were in an emotional state during the presentation of the clip. After the ANS measurements were taken, participants were asked to rate the type of emotion they had experienced as they viewed the film and to report its intensity. The results indicated that the levels of anger experienced by the AUD group were not significantly different from the emotion registered by the control group. However, the ANS responses induced in AUD participants when they were in an emotional state showed blunted skin conductance levels (SCL) and skin conductance responses (SCR) compared to the control group participants. Individuals with AUDs evinced lower emotional arousal than the participants of the control group. These results can help clinicians understand the psychological and physiological responses of individuals with AUDs to anger in order to design effective interventions that would reduce chances of anger and relapse.

• Journal of Advanced Marine Engineering and Technology
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• v.39 no.4
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• pp.443-448
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• 2015

A swirl type mixer was developed to improve the flow mixing performance of a marine selective catalytic reduction system. In this study, the swirl type mixer and a multi-staged swirl type mixer, in which the angle of the vanes at each stage is controllable were considered to provide the optimal region of angles for the mixers. The effects of the vane angles in both mixers on the uniformity index and pressure drop were investigated using a computational fluid dynamics simulation. In the swirl type mixer, the optimal conditions for the flow mixing performance were observed at vane angles from 30 to 60 degrees when vane angles could be adjusted between 10 to 80 degrees, however, the pressure drop increased continually with increasing vane angle of the mixer. On the other hand, control of the individual staged angles of the multi-staged mixer showed that it is possible to keep enhancing flow mixing performance while reducing the pressure drop.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.33 no.1
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• pp.108-113
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• 2010

The purpose of this study was to investigate the differences of driving performance and physiological responses between young male and female drivers for unexpected situation using a graphic vehicle simulator. The participants included 20 college graduates; 23 males aged $24.3\;{\pm}\;1.4$ with $2.3\;{\pm}\;1.5$ years of driving experiences and 23 females aged $23.2\;{\pm}\;2.1$ with $2.2\;{\pm}\;1.7$ years of driving experience. The participants were instructed to drive the vehicle simulator which was programed unexpected situation for two minutes. The physiological measurements used were autonomic responses of electrocardiogram (ECG) and skin conductance response (SCR), and the driving performance measurements used were the reaction time of break and the rate of collision for unexpected situation. Results showed that there were no significant differences between male and female drivers in the reaction time of break and the rate of collision for unexpected situation. Averaged R-R interval decreased and LF IHF and SCL amplitude increased for unexpected situation. There were no significant differences between male and female in the averaged R-R interval and LF/HF for unexpected situation. On the other hand, SCL amplitude of female was higher than male. Rising time to maximum SCL amplitude of female was longer than male.

• Korean Journal of Psychosomatic Medicine
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• v.3 no.2
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• pp.139-146
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• 1995

Forty patients meeting DSM-III-H criteria for panic disorder and 51 normal controls were assessed with the Personality Diagnostic Questionnaire-Revised(PDQ-R), a self-rating scale designed to assess Axis II personality disorders and traits. Results replicated previous findings of a preponderance of dependent, avoidant, and histrionic features. But our result showed other features such as paranoid, schizotypal, borderline, and antisocial traits also. Patients were divided into two groups according to the severity of their personality traits(high or low). These groups were compared in various panic symptomatology and SCL-90-R. None of the specific symptom dimensions in panic disorder, i.e. panic, anxiety, agoraphobia, social impairment, or chronicity was different between groups. Rather, high personality trait groups were found to have significantly more symptomatology in SCR-90-R than low personality groups. Result indicated that patients exhibiting a greater number of personality traits were also significantly more symptomatic. The results suggested a possible link beteween panic disorder and personality disorder. And, general factors such as depression, social or interpersonal sensitivity might provide a much better explanation of personality disorders in panic patients.

• Applied Biological Chemistry
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• v.40 no.5
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• pp.380-387
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• 1997

Phytopathogenic Erwinia carotovora subsp. carotovora (Ecc) LY34 causes plant tissue maceration by secretion of pectinolytic enzymes such as pectate Iyase (PL) existed as multiple isoenzyme form. Genomic DNA from Ecc LY34 was digested with Sau3Al and ligated into the BamHI site of pBluescript ll $SK^+$. Among them, a clone hydrolyzing polypectate was selected and its DNA was digested with BamHI. Through the subsequent subcloning the resulting 3.1 kb fragment, corresponding to a peICI, was subcloned into pLYPA 100. The structural organization of a peICI gene encoding a 374 amino acid residues consists of an open reading frame (ORF) of 1,122 bp commencing with a ATG start codon and followed by a TAA stop codon. PeICI contained a typical prokaryotic signal peptide of 22-amino acid. Since the deduced amino acid sequences of PeICl protein was very similar to those of PelIII of Erwinia carotovora subsp. carotovora, and to those of Pel3 of Erwinia carotovora subsp. atroseptica, and to those of PeIC of Erwinia carotovora subsp. carotovora, it belong to the same family PLbc group. The 374-amino acld PeICI had a calculated Mr of 40,507 and pI of 7.60.

• The KIPS Transactions:PartD
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• v.10D no.2
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• pp.233-246
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• 2003

The mediator-based system integrates heterogeneous information systems with the flexible manner. But it does not give much attention on the query optimization issues, especially for the query reusing. The other thing is that it does not use standardized metadata for schema matching. To improve this two issues, we propose mediator-based Distributed Information Integration System (DIIS) which uses query caching regarding performance and uses ISO/IEC 11179 metadata registry in terms of standardization. The DIIS is designed to provide decision-making support, which logically integrates the distributed heterogeneous business information systems based on the Web environment. We designed the system in the aspect of three-layer expression formula architecture using the layered pattern to improve the system reusability and to facilitate the system maintenance. The functionality and flow of core components of three-layer architecture are expressed in terms of process line diagrams and assembly line diagrams of Eriksson Penker Extension Model (EPEM), a methodology of an extension of UML. For the implementation, Supply Chain Management (SCM) domain is used. And we used the Web-based environment for user interface. The DIIS supports functions of query caching and query reusability through Query Function Manager (QFM) and Query Function Repository (QFR) such that it enhances the query processing speed and query reusability by caching the frequently used queries and optimizing the query cost. The DIIS solves the diverse heterogeneity problems by mapping MetaData Registry (MDR) based on ISO/IEC 11179 and Schema Repository (SCR).

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.1
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• pp.768-776
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• 2021

Current protection-coordination methods use the reverse time characteristics of the T-C curve, which is not effective for a LVDC distribution system because the protective operation time of converters and DC circuit breakers is much faster than AC protection devices. Therefore, an algorithm is proposed for fault-section isolation using the fault current slope to minimize the blackout region and coordinate between converters and protection devices in a rapid and accurate manner. The method deals with the slope characteristics of a fault current, which may depend on the fault location in an LVDC distribution system. Thus, an LVDC distribution system can be operated in a stable manner by isolating the fault section selectively before the shutdown of the main converter using slope characteristics, which change in proportion to the line impedance and fault location. A 1.5-kV LVDC distribution system was modeled to verify the effectiveness of the proposed algorithm using PSCAD/EMTDC. The system is composed of a distribution substation, LVDC converter, and distribution lines. The simulation results confirm that the proposed algorithm is a useful tool for minimizing the fault section in an LVDC distribution system.

• Clean Technology
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• v.27 no.1
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• pp.61-68
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• 2021

Selective catalytic reduction (SCR) is widely used as a method of removing nitrogen oxide in large-capacity thermal power generation systems. Uniform mixing of the injected ammonia and the inlet flue gas is very important to the performance of the denitrification reduction process in the catalyst bed. In the present study, a computational analysis technique was applied to the ammonia injection system design process of a denitrification facility. The applied model is the denitrification facility of an 800 MW class coal-fired power plant currently in operation. The flow field to be solved ranges from the inlet of the ammonia injection system to the end of the catalyst bed. The flow was analyzed in the two-dimensional domain assuming incompressible. The steady-state turbulent flow was solved with the commercial software named ANSYS-Fluent. The nozzle arrangement gap and injection flow rate in the ammonia injection system were chosen as the design parameters. A total of four (4) cases were simulated and compared. The root mean square of the NH3/NO molar ratio at the inlet of the catalyst layer was chosen as the optimization parameter and the design of the experiment was used as the base of the optimization algorithm. The case where the nozzle pitch and flow rate were adjusted at the same time was the best in terms of flow uniformity.

• Biomolecules & Therapeutics
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• v.31 no.1
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• pp.97-107
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• 2023

Aristolochic acid (AA), extracted from Aristolochiaceae plants, plays an essential role in traditional herbal medicines and is used for different diseases. However, AA has been found to be nephrotoxic and is known to cause aristolochic acid nephropathy (AAN). AA-induced acute kidney injury (AKI) is a syndrome in AAN with a high morbidity that manifests mitochondrial damage as a key part of its pathological progression. Melatonin primarily serves as a mitochondria-targeted antioxidant. However, its mitochondrial protective role in AA-induced AKI is barely reported. In this study, mice were administrated 2.5 mg/kg AA to induce AKI. Melatonin reduced the increase in Upro and Scr and attenuated the necrosis and atrophy of renal proximal tubules in mice exposed to AA. Melatonin suppressed ROS generation, MDA levels and iNOS expression and increased SOD activities in vivo and in vitro. Intriguingly, the in vivo study revealed that melatonin decreased mitochondrial fragmentation in renal proximal tubular cells and increased ATP levels in kidney tissues in response to AA. In vitro, melatonin restored the mitochondrial membrane potential (MMP) in NRK-52E and HK-2 cells and led to an elevation in ATP levels. Confocal immunofluorescence data showed that puncta containing Mito-tracker and GFP-LC3A/B were reduced, thereby impeding the mitophagy of tubular epithelial cells. Furthermore, melatonin decreased LC3A/B-II expression and increased p62 expression. The apoptosis of tubular epithelial cells induced by AA was decreased. Therefore, our findings revealed that melatonin could prevent AA-induced AKI by attenuating mitochondrial damage, which may provide a potential therapeutic method for renal AA toxicity.

• Applied Chemistry for Engineering
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• v.34 no.5
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• pp.507-514
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• 2023

The selective catalytic reduction (SCR) of nitrogen oxides (NO_x) was investigated in a catalyst (Ag/γ-Al₂O₃) packed dielectric barrier discharge plasma reactor. The intermittent generation of plasma in the catalyst bed partially oxidized the hydrocarbon reductant for NO_x removal to several aldehydes. Compared to using the catalyst alone, higher NO_x conversion was observed with the intermittent generation of plasma due to the formation of highly reductive aldehydes. Under the same operating conditions (temperature: 250 ℃; C/N: 8), the NO_x reduction efficiencies were 47.5%, 92%, and 96% for n-heptane, propionaldehyde, and butyraldehyde, respectively, demonstrating the high NO_x reduction capability of aldehydes. To determine the optimal condition for intermittent plasma generation, the high voltage on/off cycle was adjusted from 0.5 to 3 min. The NO_x reduction performance was compared between continuous and intermittent plasma generation on the same energy density basis. The highest NO_x reduction efficiency was achieved at 2-min high voltage on/off intervals. The reason that the intermittent plasma discharge exhibited higher NO_x reduction efficiency even at the same energy density, compared to the continuous plasma generation case, is that the intermediate products, such as aldehydes generated from hydrocarbon, were more efficiently utilized for the reduction of nitrogen oxides.