• Title/Summary/Keyword: S100A7

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Physiological Activity of Coffee Beans and Roasted Black Beans (Rhynchosia nulubilis) Mixture Extracts for Coffee Alternative Beverage Development

  • Kim, Ae-Jung;Lee, Hankyu;Ko, Hyuk Wan;Ko, Seong Hee;Woo, Nariyah
    • The Korean Journal of Food And Nutrition
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    • v.29 no.2
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    • pp.178-185
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    • 2016
  • This study was designed to develop and to qualify a coffee alternative beverage using a mixture of coffee beans and roasted black beans (Rhynchosia nulubilis). Therefore, the total isoflavone content (TIC), total phenol content (TPC), antioxidant activity, anti-inflammatory activity, NFATc1 (Nuclear factor of activated T-cells c1) expression in RANKL (receptor activator of nuclear factor kappa-B ligand)-stimulated RAW264.7 cells and sensory evaluation were measured for 5 different Cb (coffee bean)-RoS (roasted seomoktae) mixture extracts (Cb100RoS0, Cb75RoS25, Cb50RoS50, Cb25RoS75, and Cb0RoS100). Cb0RoS100 had the highest TIC ($516.83{\pm}36.61mg/100g$) and TPC ($18.11{\pm}1.77mg$ TAE/100 g) along with the highest antioxidant activity as measured by DPPH radical scavenging activity ($73.55{\pm}8.11%$) and ABTS radical scavenging activity ($63.27{\pm}7.27%$). Also, Cb0RoS100 showed the highest anti-inflammatory activity as measured by NO production ($13.57{\pm}2.21{\mu}M$) and PGE2 production ($3.25{\pm}0.21ng/mL$). The more the RoS ratio was increased in the mixtures of Cb-RoS, the more the NFATc1 protein expression was decreased in RANKL-stimulated RAW264.7 cells. In case of sensory evaluation, Cb50RoS50 had the highest scores for flavor, delicate flavor and overall quality, which were similar to those in Cb alone (Cb100RoS0). We suggest that the use of RoS replacement instead of Cb in/as a coffee alternative beverage may help to reduce the risk of caffeine-related bone loss and/or bone disease by effectively blocking NFATc1 expression in RANKL-stimulated RAW264.7 cells compared with Cb alone.

Relation between Serum S100β and Severity and Prognosis in Traumatic Brain Injury (외상성 뇌손상 환자에 있어서 S100β의 혈중 농도와 뇌손상의 정도 및 예후의 관계)

  • Kim, Oh Hyun;Lee, Kang Hyun;Yoon, Kap Jun;Park, Kyung Hye;Jang, Yong Su;Kim, Hyun;Hwang, Sung Oh
    • Journal of Trauma and Injury
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    • v.20 no.2
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    • pp.138-143
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    • 2007
  • Purpose: $S100{\beta}$, a marker of traumatic brain injury (TBI), has been increasingly focused upon during recent years. $S100{\beta}$, is easily measured not only in cerebrospinal fluid (CSF) but also in serum. After TBI, serum S 10019, has been found to be increased at an early stage. The purpose of this study was to evaluate the clinical correlations between serum $S100{\beta}$, and neurologic outcome, and severity in traumatic brain injury. Methods: From August 2006 to October 2006, we made a protocol and studied prospectively 42 patients who visited the emergency room with TBI. Venous blood samples for $S100{\beta}$, protein were taken within six hours after TBI and vital signs, as well as the Glasgow Coma Scale (GCS), were recorded. The final diagnosis and the severity were evaluated using the Abbreviated Injury Score (AIS), and the prognosis of the patients was evaluated using the Glasgow Outcome Score (GOS). Results: Thirty-eight patients showed a favorable prognosis (discharge, recovery, transfer), and four showed an unfavorable prognosis. Serum $S100{\beta}$, was higher in patients with an unfavorable prognosis than in patients with a favorable prognosis, and a significant difference existed between the two groups ($0.74{\pm}1.50\;{\mu}g/L$ vs $7.62{\pm}6.53\;{\mu}g/L$ P=0.002). A negative correlation existed between serum $S100{\beta}$, and the Revised Traumatic Score (R2=-0.34, P=0.03), and a positive correlation existed between serum $S100{\beta}$, and the Injury Severity Score (R2=0.33, P=0.03). Furthermore, the correlation between serum $S100{\beta}$, and the initial GCS and the GCS 24 hours after admission to the ER were negative (R2=-0.62, P<0.001; R2=-0.47, P=0.005). Regarding the GOS, the mean serum concentration of $S100{\beta}$, was $7.62\;{\ss}{\partial}/L$ (SD=${\pm}6.53$) in the expired patients, $1.15\;{\mu}g/L$ in the mildly disable patient, and $0.727\;{\mu}g/L$ (SD=${\pm}0.73$) in the recovered patients. These differences are statistically significant (p<0.001). Conclusion: In traumatic brain injury, a higher level of serum concentration of $S100{\beta}$, has a poor prognosis for neurologic outcome.

AN EXPERIMENTAL STUDY ON COEFFICIENT OF THERMAL EXPANSION OF DENTAL INVESTMENTS (수종치과매몰재(數種齒科埋沒材)의 열팽창계수(熱膨脹係數)에 관(關)한 실험적(實驗的) 연구(硏究))

  • Lee, Myung-Jong
    • Restorative Dentistry and Endodontics
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    • v.5 no.1
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    • pp.29-34
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    • 1979
  • The purpose of this study was to measure thermal expansions of dental investments, Biovest(Casting Investment. Dentsply International INC, U.S.A.), Multi-Best (Use for all dental chrome-cobalt alloys, The Ransom & Randolph Co. U.S.A.), Kerr(Inlay Investment. Sybron Kerr, U.S.A.), O. K. (Inlay Investment. Shofu Dental MFG, Co. Japan), Whip-Mix (Cristobalite Inlay Investment. Whip-Mix Corporation. U.S.A.). Thermal expansion of specimens(5mm in diameter and 50mm in length) was measured by a dilatometer at the temperature range from $20^{\circ}C$ to $700^{\circ}C$ by comparing expansion between standardized quartz and experimental specimens with heating rate about $300^{\circ}C$/hr. The following results were obtained. 1. The coefficient of thermal expansion of Biovest was $15{\times}10^{-6}/^{\circ}C$ in the water powder ratio 18/100 and $14{\times}10^{-6}/^{\circ}C$ in the water powder ratio 28/100. Those of Multi-Best were $9{\times}10^{-6}/^{\circ}C$ in the water powder ratio 14/100 and $7{\times}10^{-6}/^{\circ}C$ in the water powder ratio 24/100. 2. The coefficient of thermal expansion of Kerr were $17{\times}10^{-6}/^{\circ}C$ in the water powder ratio 38/100 and $14{\times}10^{-6}/^{\circ}c$ in the water powder ratio 48/100. Those of O. K. were $9{\times}10^{-6}/^{\circ}C$ in the water powder ratio 33/100 and $7{\times}10^{-6}/^{\circ}C$ in the water powder ratio 43/100 3. The coefficient of thermal expansion of Whip-Mix were $14{\times}10^{-6}/^{\circ}C$ in the water powder ritio 40/100 and $12{\times}10^{-6}/^{\circ}c$ Fein the water powder ratio 50/100. Those of Hi-Heat were $11{\times}10^{-6}/^{\circ}c$ in the water powder ratio 28/100 and $10{\times}10^{-6}/^{\circ}c$ in the water powder ratio 38/100.

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Grapefruit Seed Extract (DF-100) Treatment of Poultry to Reduce Attached Salmonella

  • Mike F. Slavik;Kim, Jeong-Weon;Phil L. Matsler;Hong Wang
    • Journal of Food Hygiene and Safety
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    • v.11 no.1
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    • pp.7-10
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    • 1996
  • Chicken skins or carcasses inoculated with Salmonella typhimurium were exposed to 0.1 or 0.5% grapefruit seed extracts (DF-100) for 1 or 3 min to evaluate antibacterial activity of DF-100 and its possible application in proultry processing. The numbers of live salmonellae on chicken skins were reduced by 0.8-1.2 logs/cm2 with 0.5% DF-100. Dipping chicken carcasses into 0.5% DF-100 for 3 min reduced salmonelae by 4.3 logs/carcass. Scanning electron microscopy showed that DF-100 killed the cells attached but did not detach cells from the skin. No odor or changes in the color of chicken skin were detected after DF-100 treatment.

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Acinetobacter marinus sp. novo and Acinetobacter seohaensis sp. nov., Isolated from Sea Water of the Yellow Sea in Korea

  • Yoon, Jung-Hoon;Kim, In-Gi;Oh, Tae-Kwang
    • Journal of Microbiology and Biotechnology
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    • v.17 no.11
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    • pp.1743-1750
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    • 2007
  • Two Gram-negative, nonmotile, coccobacilli, SW-$3^T$ and SW-$100^T$, were isolated from sea water of the Yellow Sea in Korea. Strains SW-$3^T$ and SW-$100^T$ contained ubiquinone-9 (Q-9) as the predominant respiratory lipoquinone and $C_{18:1}\;{\omega}9c$ and $C_{16:0}$ as the major fatty acids. The DNA G+C contents of strains SW-$3^T$ and SW- $100^T$ were 44.1 mol% and 41.9 mol%, respectively. A neighbor-joining tree based on l6S rRNA gene sequences showed that the two isolates fell within the evolutionary radiation enclosed by the genus Acinetobacter. Strains SW-$3^T$ and SW-$100^T$ exhibited a l6S rRNA gene similarity value of 95.7% and a mean DNA-DNA relatedness level of 9.2%. Strain SW-$3^T$ exhibited l6S rRNA gene sequence similarity levels of 93.5-96.9% to the validly described Acinetobacter species and fifteen Acinetobacter genomic species. Strain SW-$100^T$ exhibited l6S rRNA gene sequence similarity levels of less than 97.0% to the other Acinetobacter species except Acinetobacter towneri DSM $14962^T$ (98.0% similarity). Strains SW-$3^T$ and SW-$100^T$ exhibited mean levels of DNA-DNA relatedness of 7.3-l6.7% to the type strains of some phylogenetically related Acinetobacter species. On the basis of phenotypic, phylogenetic, and genetic data, strains SW-$3^T$ and SW-$100^T$ were classified in the genus Acinetobacter as two distinct novel species, for which the names Acinetobacter marinus sp. novo (type strain SW-$3^T$=KCTC $12259^T$=DSM $16312^T$) and Acinetobacter seohaensis sp. novo (type strain SW-$100^T$=KCTC $12260^T$=DSM $16313^T$) are proposed, respectively.

The Effect of Hominis Placenta Herbal Acupuncture on Bell's palsy (자하거약침(紫河車藥鍼)의 Bell's palsy에 대한 치험보고(治驗報告))

  • Yun, Jeong-Hun;Yook, Tea-Han;Song, Beom-Yong
    • Journal of Pharmacopuncture
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    • v.3 no.1
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    • pp.89-99
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    • 2000
  • This report was done to observe the effect of Hominis placenta herbal acupuncture on Bell's palsy. The study group comprised 16 patients who arrived at Woo-suk university oriental hospital from January, 1999 till January, 2000 for Bell's palsy. All patients were divided into two group. One was herbal acupunture group, and the other was control group. Acupunture group was done herbal acupuncture therapy on the facial acupuncture points. Followings are achievement and a term of each group. In herbal acupuncture group, 100% motor recovery was 7 case, 75% was 1 case, and 25% motor recovery term was $7.38{\pm}5.21$ days, 50% was $11.00{\pm}6.16$ days, 75% was $15.13{\pm}9.55$ days, 100% was $23.14{\pm}7.97$ days. In control group, 100% motor recovery was 4 case, 75% was 2 case, 25% below was 2 case and 25% motor recovery term was $11.17{\pm}4.96$days, 50% was $18.17{\pm}6.82$ days, 75% was $29.50{\pm}6.95$ days, 100% was $44.00{\pm}11.49$ days. The above results indicate that Hominis placenta herbal acupuncture is a useful effect on Bell's palsy. thus, continuous herbal acupunture study will be needed for more clinical application on Bell' palsy.

Composition of Vitamin A, E, $B_l$ and $B_2$ Contents in Korean Cow's Raw Milk in Korea (국내산 원유 중 비타민 A, E, $B_l$$B_2$ 함량에 관한 연구)

  • Kwak Byung-Man;Kim Sung-Han;Kim Kang-Seob;Lee Ki-Woong;Ahn Jang-Hyuk;Jang Chi-Hoon
    • Food Science of Animal Resources
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    • v.26 no.2
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    • pp.245-251
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    • 2006
  • This study was performed to investigate the changes of vitamin A, vitamin E, vitamin $B_l$ and vitamin $B_2$ contents in cow's raw milk collected from dairy farms in Chungcheong-do and Jeolla-do for a year. The contents of fat soluble vitamin A and E were changed as seasonal effect, but water soluble vitamin $B_l$ and $B_2$ contents were not changed as seasonal effect. Vitamin A content in cow's raw milk was as follows [minimum ${\sim}$maximum (mean), ug/100 mL]; $35.1{\sim}59.0$ (44.4) in spring, $36.7{\sim}65.6$ (50.0) in summer, $28.7{\sim}61.2$ (46.8) in autumn and $29.9{\sim}57.8$ (43.1) in winter. In case of vitamin E was as follows [minimum${\sim}$maximum (mean), ug/100 mL]; $28.3{\sim}59.2$ (45.8) in spring, $39.6{\sim}69.9$ (58.8) in summer, $35.0{\sim}62.8$ (46.2) in autumn and $26.0{\sim}55.4$ (41.5) in winter. In case of vitamin $B_l$ was as follow [minimum${\sim}$maximum (mean), ug/100 mL]; $27.7{\sim}57.9$ (42.84) in spring, $32.4{\sim}66.1$ (49.39) in summer, $34.1{\sim}63.7$ (46.69) in autumn and $20.6{\sim}61.4$ (43.20 in winter. The amounts of vitamin $B_2$ in cow's raw milk was as follows [minimum${\sim}$maximum (mean), ug/100 mL]; $150{\sim}182$ (160 in spring, $145{\sim}185$ (163) in summer, $149{\sim}180$ (166) in autumn and $148{\sim}190$ (167) in winter.

Correlation of serum S100B levels with brain magnetic resonance imaging abnormalities in children with status epilepticus

  • Gunawan, Prastiya Indra;Saharso, Darto;Sari, Dian Purnama
    • Clinical and Experimental Pediatrics
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    • v.62 no.7
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    • pp.281-285
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    • 2019
  • Purpose: To evaluate the association between elevated S100B levels with brain tissue damage seen in abnormalities of head magnetic resonance imaging (MRI; diffusion tensor imaging [DTI] sequence) in patients with status epilepticus (SE). Methods: An analytical observational study was conducted in children hospitalized at Dr Soetomo Hospital, Surabaya, from July to December 2016. The patients were divided into 2 groups: SE included all children with a history of SE; control included all children with febrile seizure. Blood samples of patients were drawn within 24 hours after admission. SE patients also underwent cranial MRI with additional DTI sequencing. The Mann-Whitney test and Spearman test were used for statistical analysis. Results: Fifty-three patients were enrolled the study. In the 24 children with SE who met the inclusion criteria, serum S100B and cranial MRI findings were assessed. Twenty-two children admitted with febrile seizures became the control group. Most patients were male (66.7%); the mean age was 35.8 months (standard deviation, 31.09). Mean S100B values of the SE group ($3.430{\pm}0.141{\mu}g/L$) and the control group ($2.998{\pm}0.572{\mu}g/L$) were significantly different (P<0.05). A significant difference was noted among each level of encephalopathy based on the cranial MRI results with serum S100B levels and the correlation was strongly positive with a coefficient value of 0.758 (P<0.001). Conclusion: In SE patients, there is an increase of serum S100B levels within 24 hours after seizure, which has a strong positive correlation with brain damage seen in head MRI and DTI.

High-Performance Low-Complexity Iterative BCH Decoder Architecture for 100 Gb/s Optical Communications (100 Gb/s급 광통신시스템을 위한 고성능 저면적 반복 BCH 복호기 구조)

  • Yang, Seung-Jun;Yeon, Jaewoong;Lee, Hanho
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.7
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    • pp.140-148
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    • 2013
  • This paper presents a iterative Bose-Chaudhuri-hocquenghem (i-BCH) code and its high-speed decoder architecture for 100 Gb/s optical communications. The proposed architecture features a very high data processing rate as well as excellent error correction capability. The proposed 6-iteration i-BCH code structure with interleaving method allows the decoder to achieve 9.34 dB net coding gain performance at $10^{-15}$ decoder output bit error rate to compensate for serious transmission quality degradation. The proposed high-speed i-BCH decoder architecture is synthesized using a 90-nm CMOS technology. It can operate at a clock frequency of 430 MHz and achieve a data processing rate of 100 Gb/s. Thus, it has potential applications in next generation forward error correction (FEC) schemes for 100 Gb/s optical communications.

Characteristics of Sanghwabyung(traditional leavened bread)made with Black-wheat Flour (흑밀가루로 제조한 상화병의 품질특성)

  • Lee, Soon-Young;Ko, Seong-Hee;Choi, Won-Surk;Han, Young-Sook
    • Korean journal of food and cookery science
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    • v.28 no.4
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    • pp.383-390
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    • 2012
  • In order to reproduce Sanghwabyung that people in the past made and ate at Yuduil (June 6th by lunar calendar) among our traditional rice cakes, this study manufactured Sanghwabyung with black wheat flour by adding the wheat bran and Nuruk powder as leavening source, according to the old cook book "Gyuhapchongseo" and analyzed the quality characteristics. As a result of total phenol and flavonoid contents, DPPH radical scavenging activity of black wheat contents showed the gradual increase significantly (p < 0.001). The number of lactic acid bacteria was $6.72{\times}10^7$ CFU/mL just after preparation, and the number of yeast was $5.59{\times}10^7 $ CFU/mL. The number of lactic acid bacteria and yeast increased after 24 h to $8.48{\times}10^7$ CFU/mL and $5.40{\times}10^7$ CFU/mL. Hard-ness was the lowest in WF30%, compared with the C and the highest in BF100% and WF100%. The more the added portion increased in WF30% and BF30%, the more the hardness increased significantly (p < 0.001). The cohesiveness was the highest in WF30%, compared with C and BF30%, the lowest. It was shown significantly different between the C and WF and BF sample groups (p < 0.01). Springiness was the highest in WF10% and WF50%, compared with that in C and BF100%, which were the lowest. Springiness decreased significantly (p < 0.001) ad-ded portion increased between WF30% and BF30%. Gumminess was the highest in BF100% and WF100%, whereas that of WF20% was the lowest (p < 0.001). Chew-iness was the highest in BF100% and WF100% (p < 0.001).