• The Journal of Korean Society for Radiation Therapy
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• v.30 no.1_2
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• pp.177-183
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• 2018

Purpose : Volumetric Modulated Arc Therapy(VMAT) has the advantage of uniformly and precisely irradiating the tumor to the shape of the tumor while reducing the risk of radiation damage to normal tissues. such as brain cancer, head and neck cancer and prostate cancer, It is being used for treatment. The purpose of this study is to evaluate the usefulness of the Jaw-Tracking technique(JTT) in VMAT for brain and head and neck cancer. Materials and Methods : We selected eight patients with brain and head and neck cancer(4 Brain, 4 head and neck) who were treated with the VMAT treatment technique. Contouring information of the patient's tumor and normal organ was fused to the Rando phantom using the deformable registration of Velocity(Varian, USA). A treatment plan was developed using the Varian Eclipse(ver 15.5, Varian, USA) with the same patient actual beam parameters except for the use of jaw-tracking. As the evaluation index, the maximum dose and mean dose of target and OAR were compared and a portal dosimetry was performed for the treatment plan verification. Results : When using JTT, the relative dose of OAR decreased by 5.24 % and the maximum dose by 7.05 %, respectively, compared with the Static-Jaw technique(SJT). In the various OARs, the mean dose and maximum dose reduction ranges ranged from 0.01 to 3.16 Gy and from 0.12 to 6.27 Gy, respectively. In the case of the target, the maximum dose of GTV, CTV, PTV decreased by 0.17 %, 0.43 %, and 0.37 % in JTT, and the mean dose decreased by 0.24 %, 0.47 % and 0.47 %, respectively. Gamma analysis The JTT and SJT passing rates were $98{\pm}1.73%$ and $97{\pm}1.83%$ on the basis of 3 % / 3 mm, respectively. Comparing the doses of all OARs applied to the experiment, it was found that the use of JTT resulted in a significant decrease in dose due to additional jaw shielding besides MLC than SJT. Conclusion : In radiation therapy using VMAT treatment plan, we can apply JTT in the case of adjacent tumor and normal organs such as brain cancer and head and neck cancer, and in radiotherapy required large field and high energy caused increase leakage dose through MLC. It is considered that the target dose of PTV can be increased by lowering the dose of normal tissue surrounding the tumor.

• Journal of Bio-Environment Control
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• v.28 no.4
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• pp.429-437
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• 2019

This study was conducted to examine the effect of humidification and shading during cutting propagation on growth and development of strawberry (Fragaria x ananassa Duch.) 'Maehyang' plants at a propagation stage. The runner cuttings were stuck on Nov. 23, 2017 in propagation benches set in a Venlo-type glasshouse. Four shading treatments, no shading (control, C), 55% shading with white lawn (W55), 55% black shading net (B55), or 100% black plastic film (B100) with either an intermittent fog system (H) or without fog system. The shading and fog systems were removed 2 weeks after sticking of strawberry cuttings. A nutrient solution for strawberry, which was developed by Yamazaki, was supplied once a day with electrical conductivity (EC) $1.6dS{\cdot}m^{-1}$ and pH 5.8. Growth parameters such as plant height, longest root, crown diameter, leaf chlorophyll, leaf area and fresh and dry weight were measured at 7 days and 26 days after sticking. There was no significant difference in growth of above-aerial part of strawberry. The overall growth of the strawberry roots was better grew by providing fog than that not provide fog. The root fresh weight and root dry weight after 26 days after sticking of strawberry cutting was the best in the treatment that provided fog system without shading (CH). The longest root after 26 days after sticking of strawberry cutting was the best in the treatments that provided fog system with either 55% white lawn (W55H) and 55% black shading net (B55H). These results suggest that morphogenesis of these plants were affected by humidification and shading types. In a broader perspective, these results can be used to optimize studies of other crops grown from cuttings.

• Geophysics and Geophysical Exploration
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• v.1 no.1
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• pp.25-30
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• 1998

Time-lapse crosswell seismic data, recorded before and after the cavity filling, showed that the filling increased the velocity at a known cavity zone in an old mine site in Inchon area. The seismic response depicted on the tomogram and in conjunction with the geologic data from drillings imply that the size of the cavity may be either small or filled by debris. In this study, I attempted to evaluate the filling effect by analyzing velocity measured from the time-lapse tomograms. The data acquired by a downhole airgun and 24-channel hydrophone system revealed that there exists measurable amounts of source statics. I presented a methodology to estimate the source statics. The procedure for this method is: 1) examine the source firing-time for each source, and remove the effect of irregular firing time, and 2) estimate the residual statics caused by inaccurate source positioning. This proposed multi-step inversion may reduce high frequency numerical noise and enhance the resolution at the zone of interest. The multi-step inversion with different starting models successfully shows the subtle velocity changes at the small cavity zone. The inversion procedure is: 1) conduct an inversion using regular sized cells, and generate an image of gross velocity structure by applying a 2-D median filter on the resulting tomogram, and 2) construct the starting velocity model by modifying the final velocity model from the first phase. The model was modified so that the zone of interest consists of small-sized grids. The final velocity model developed from the baseline survey was as a starting velocity model on the monitor inversion. Since we expected a velocity change only in the cavity zone, in the monitor inversion, we can significantly reduce the number of model parameters by fixing the model out-side the cavity zone equal to the baseline model.

• Korean Journal of Soil Science and Fertilizer
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• v.34 no.1
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• pp.26-32
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• 2001

Influence of various rates of fractionated raw cow manure on hydraulic conductivity of the soil was observed. The fractionated raw cow manure(hereafter as FRCM) incorporated into soil. The hydraulic conductivity was measured for the double-layered soil while maintaining the water head by 5 cm over the soil surface. The influence on the mobility of $NO_3{^-}$-N transformed from the FRCM was analyzed. The upper layers (Wolgok series) were made with FRCM ranging from 0% to 10.4 % on weight basis for air-dried soil while the organic matter in the bottom layers (Chungwon series) was removed by combustion. The initial bulk densities for both layers were adjusted to $1.25g\;cm^{-3}$. In this experiment the $K_{sat}$ for the upper layer gradually decreased from $4.71{\times}10^{-3}cm\;min^{-1}$ to $1.2{\times}10^{-3}cm\;min^{-1}$ with increasing the rate of the FRCM from 0 % to 10.4%, while the Ksat of the bottom layer was maintained as $3.7cm\;min^{-1}$. For the double-layered soil columns, the $K_{sat}$ decreased with increasing rate of FRCM at the upper layer from $1.7{\times}10^{-3}cm\;min^{-1}$ to $8{\times}10^{-4}cm\;min^{-1}$ as the rate of organic matter increased from 0 % to 10.4 %, while it took almost 7 days to 64 days to obtain the steady state $K_{sat}$ The elution patterns of $NO_3{^-}$-N and $NH_4{^+}$-N showed that the amounts of both $NO_3{^-}$-N and $NH_4{^+}$-N rapidly approached to the maximum ranging from $14.8mmol_c\;kg^{-1}$ to $0.58mmol_c\;kg^{-1}$ as the rate of FRCM decreased from 10.7 % to 0 % which is equivalent to indigenous amount of $NO_3{^-}$-N and $NH_4{^+}$-N. And the amounts of $NO_3{^-}$-N were approximately three or four time than those of $NH_4{^+}$-N, indicating that the transformation rate of $NO_3{^-}$-N was improved by the higher FRCM rate. Thus, the ability of a soil to supply N can be predicted from its mineralization parameters and leaching potentials influenced by water flow regime in soil.

• Korean Journal of Soil Science and Fertilizer
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• v.32 no.4
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• pp.398-404
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• 1999

Factor analysis technique was employed to screen the principal indicators influencing soil and water qualities in the intensively cultivated areas of the Han River Basin. Soil chemical parameters were analyzed for the soil samples collected at intensive farming area in Pyungchang-Gun, and water quality monitoring data were obtained from the agricultural small catchments of Han River Basin during 1996 and 1997. Among the $11{\times}11$ cross correlation matrix, 29 correlations were significant out of 55 soil quality indicator pairs. The overall Kaiser's measure of sampling adequacy(KMS) value was acceptable with 0.60. Most indicators except iron were acceptable. Among soil indicators, the first factors showing high factor loadings were pH, Ca and Mg. The factor loading was the highest for Ca. The second factor could be characterized as phosphate and micronutrient. The third factor was organic matter and EC, and the fourth factor was potassium and Fe. Out of 190 water quality indicators, 86 correlations were significant. Overall KMS value was 0.74, but the KMS values for pH, TSS, Cd, Cu and Fe were lower than 50. The first factor of EC accounts 27.1 percents of the total variance, and showed high factor loadings with Na, Ca, $SO_4$, Mg, K, Cl, $NO_3$, and T-N. The second factor showed high loadings with Zn, Fe, Mn and Cd. The third to seventh factors could be characterized as $PO_4$, TSS, inorganic nitrogen, pH and T-P, and Cu factors, respectively. The factor score for EC was the highest in Kuri, followed by Chunchon, Dunnae and Daegwanryng. The factor score for heavy metals were the highest in the Daegwanryng. The results demonstrated that the factor analysis could be useful to select the most principal factor influencing soil and water qualities in the agricultural watershed.

• Journal of Korean Society of Forest Science
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• v.110 no.4
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• pp.678-688
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• 2021

This study was conducted to provide growth characteristics and stand information in preparation for natural regeneration method and silvicultural treatment of seed tree method in Korean red pine stands by using the field inventoried data 18 years after the seed tree regeneration method in 2001 and analyzing the stand and sapling characteristics. The study area was located in the Research Forest of Kangwon National University, Chuncheon-si, Gangwon-do. In November 2018, we collected tree measurement factors, such as diameter at breast height (DBH), height, crown class, stem quality, tree age, and annual height increment on the established plots. We calculated the basal area, volume, height-diameter ratio (HD ratio), and additional stand density variables such as the relative density and %stocking to analyze the managed stands. The number of mother trees was 58 trees/ha, with a 17.7% stocking level, whereas the number of saplings was 2,330 trees/ha, with a 79.0% stocking level. In germination, the age distribution of saplings ranged from 2001 to 2007, with most belonging to 15-16 years. The development condition of saplings was 10 cm in DBH and 8 m in height. DBH and height were higher as the crown class is more dominant, and this difference was statistically significant in the analysis of variance and Duncan's multiple comparison test (p<0.0001). HD ratio ranged mostly between 80% and 90%, and more than 95% of sapling stems were of high quality, with a straight, unbroken top, non-sweep, and non-diseased stem. On average, the annual height increment of saplings was 21.9 cm at 1 year, 43.3 cm at 5 years, 54.3 cm at 10 years, and 64.3 cm at 15 years. The overall height growth with age increased smoothly. According to the analysis of covariance, the annual height growth by crown class differed significantly. The regression analysis parameters revealed that annual height growth increased with age and dominant crown class.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.18 no.3
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• pp.78-86
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• 2018

Purpose: We aimed to delineate clinical spectrum and short-term effects after enzyme replacement therapy (ERT) for 5 mucopolysaccharidosis type II (MPS II). Methods: Five patients were diagnosed with MPS II by clinical findings, enzyme activity, and genetic testing. Idursulfase was administered by intravenous infusion at a dose of 0.5 mg/kg every week. Observational chart analysis of patients, who underwent systematic investigations more than 12 months after initiation of ERT was done retrospectively. Results: Three patients were classified as having the attenuated type, and 2 patients were classified as having the severe type. The median age at the diagnosis was 9.6 years (range 3.4-26 years). Four different mutations in 5 Korean patients (4 families) with MPS II were identified, among which two were novel mutations (1 small insertion mutation: p.Thr409Hisfs*22, and 1 missense mutation: p.Gly134Glu). Two severe type sibling patients with the same mutation had different clinical manifestation. Urinary glycosaminoglycan excretion decreased within the twelve months of ERT (P=0.043). Liver and spleen volumes showed reductions that were maintained in all patients (P=0.043 and P=0.043, respectively). Improvements were also noted in left ventricular mass index (P=0.042), shoulder flexion (P=0.043), shoulder abduction (P=0.039), knee flexion (P=0.043), elbow flexion (P=0.042), and respiratory distress index (P=0.041). Conclusion: This study demonstrates that Korean patients with MPS II are clinically heterogeneous and indicates that idursulfase is relatively effective in several clinical parameters including heart size and respiratory distress index without infusion-related reactions in patients with MPS II.

• Journal of Climate Change Research
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• v.1 no.1
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• pp.31-50
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• 2010

The Arctic climate change for the Last Glacial Maximum(LGM) occurred at 21,000 years ago (21ka) was investigated using simulation results of atmosphere-ocean coupled models from the second phase of the Paleoclimate Modelling Intercomparison Program(PMIP2). In the analysis, we used seven models, the NCAR CCSM of USA, ECHAM3-MPIOM of German Max-Planxk Institute, HadCM3M2 of UK Met Office, IPSL-CM4 of France Laplace Institute, CNRM-CM3 of France Meteorological Institute, MIROC3.2 of Japan CCSR at University of Tokyo, and FGOALS of China Institute of Atmospheric Physics. All the seven models reproduces the Arctic climate features found in the present climate at 0ka(pre-industrial time) in a reasonable degree in comparison to observations. During the LGM, the atmospheric $CO_2$ concentration and other greenhouse gases were reduced, the ice sheets were expanded over North America and northern Europe, the sea level was lowered by about 120m, and orbital parameters were slightly different. These boundary conditions were implemented to simulated LGM climate. With the implemented LGM conditions, the biggest temperature reduction by more than $24^{\circ}C$ is found over North America and northern Europe owing to ice albedo feedback and the change in lapse rate by high elevation. Besides, the expansion of ice sheets leads to the marked temperature reduction by more then $10^{\circ}C$ over the Arctic Ocean. The temperature reduction in northern winter is larger than in summer around the Arctic and the annual mean temperature is reduced by about $14^{\circ}C$. Compared to low mid-latitudes, the temperature reduction is much larger in high northern altitudes in the LGM. This results mirror the larger warming around the Artic in recent century. We could draw some information for the future under global warming from the knowledge of the LGM.

• Korean Journal of Environmental Agriculture
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• v.37 no.4
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• pp.251-259
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• 2018

BACKGROUND: Various culture media have been used for hydroponic cultures of horticultural plants under the smart greenhouses with natural and artificial light types. Management of the culture medium for the control of medium amounts and/or necessary components absorbed by plants during the cultivation period is performed with ICT (Information and Communication Technology) and/or IoT (Internet of Things) in a smart farm system. This study was conducted to develop the cloud-based data analysis system for effective management of culture medium applying to hydroponic culture and plant growth in smart greenhouses. METHODS AND RESULTS: Conventional inorganic Yamazaki and organic media derived from agricultural byproducts such as a immature fruit, leaf, or stem were used for hydroponic culture media. Component changes of the solutions according to the growth stage were monitored and plant growth was observed. Red and green lettuce seedlings (Lactuca sativa L.) which developed 2~3 true leaves were considered as plant materials. The seedlings were hydroponically grown in the smart greenhouse with fluorescent and light-emitting diodes (LEDs) lights of $150{\mu}mol/m^2/s$ light intensity for 35 days. Growth data of the seedlings were classified and stored to develop the relational database in the virtual machine which was generated from an open stack cloud system on the base of growth parameter. Relation of the plant growth and nutrient absorption pattern of 9 inorganic components inside the media during the cultivation period was investigated. The stored data associated with component changes and growth parameters were visualized on the web through the web framework and Node JS. CONCLUSION: Time-series changes of inorganic components in the culture media were observed. The increases of the unfolded leaves or fresh weight of the seedlings were mainly dependent on the macroelements such as a $NO_3-N$, and affected by the different inorganic and organic media. Though the data analysis system was developed, actual measurement data were offered by using the user smart device, and analysis and comparison of the data were visualized graphically in time series based on the cloud database. Agricultural management in data visualization and/or plant growth can be implemented by the data analysis system under whole agricultural sites regardless of various culture environmental changes.

• The Journal of Korean Society for Radiation Therapy
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• v.30 no.1_2
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• pp.153-160
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• 2018

Purpose : We retrospectively analyzed doses of each radiation therapy technique used in the treatment for left breast cancer patients after partial mastectomy through dose results for normalorgans and tumor volume to use this as a clinical reference for radiation therapy of domestic left breast cancer patients. Materials and Methods : 40 patients who underwent partial mastectomy on left breast cancer were classified in 3 treatment methods. The treatment plan was evaluated by HI(homogeneity index), $D_{95%}$, and CI(conformity index), and the $V_{hot}$ for gross tumor volume and clinical target volume of each treatment method. In Cyberknife treatment, tumor volume was the same as high dose volume in the other techniques, so no consideration was given to clinical target volume. Treatment plan evaluation for normal organs were evaluated by mean dose on ipsilateral lung, heart, left anterior descending artery, opposite breast and lung, and non-target tissue. Result : Treatment with volumetric arc radiotherapy(VMAT) showed $95.84{\pm}0.75%$ of $D_{95%}$ on the clinical target volume, significantly higher than that of 3D-CRT. The $D_{95%}$ value of the total tumor volume was slightly higher than the other treatments. In Cyberknife treatment, the dose to the normal organs was significantly lower than other treatments. Overall, the maximum dose and mean dose to the heart were $26.2{\pm}6.12Gy$ and $1.88{\pm}0.2Gy$ in VMAT treatment and $20.25{\pm}9.35Gy$ and $1.04{\pm}0.19Gy$ in 3D-CRT therapy, respectively. Conclusion : In comparison on 3D-CRT and VMAT, most of the dosimetric parameters for the evaluation of the treatment plan showed similar values, so that there is no significant difference in treatment plan evaluation. It is possible to select the treatment method according to the patient's anatomical structure or possibility of breath control. Cyberknife treatment is very useful treatment for normal organs because of its accurate dose exposure to the tumor volume However, it has restrictions to treat the local area, to have relatively long treatment time and to involve invasive procedure.