• Title/Summary/Keyword: S-Triazolo[3,4-b]-1,3,4-thiadiazoles

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Synthesis of New Salicylamide Derivatives with Evaluation of Their Antiinflammatory, Analgesic and Antipyretic Activities

  • Fahmy, H.H.;Soliman, G.A.
    • Archives of Pharmacal Research
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    • v.24 no.3
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    • pp.180-189
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    • 2001
  • A new series of pyridazine, pyrazoles, pyrazolidine-3,5-dione, Semicarbazide, thiosemicarbazides, hydantoin, thiohydantoins, 1,2,4-triazoles, S-triazolo[3,4-b]-1,3,4-thiadiazoles incorporated indirectly into salicylamide moiety at position 2 were synthesized. Also the synthesis of novel series of 3-salicylamido-2-hydroxypropyl-amino derivatives were prepared. Several of these compounds were screened for antiinflammatory, analgesic, antipyretic and ulcerogenic activities.

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