• Korean Journal of Plant Resources
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• v.8 no.3
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• pp.237-246
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• 1995

In this study, the callus was induced and regenerated from the immature embryo and ultrastructural characteristics of developmental stages in Citrus junos SIEB, were investigated. The yellowish callus was induced by 5 to 6 week of culture of citrus. In proliferation callus after 6 weeks of culture, large vacuole was formed by fusion between adjacent small ones. In the non-embryogenic callus cultured for 12weeks, re-differentiated cells of callus showed the large nucleus with globular nucleus and amyloplast with large size of starches. In the embryogenic callus cltured for 14-16 weeks, the active exocytosis occurred in cells, secretory vesicles appeared on cell membrane and small particles from cytoplasm were released to intercelluar space. In the embryogenic callus cultured for 24 weeks, a sperical type of chloroplast bounded on cytoplasm by double membrane and typical grana was dispersed equally among matrix. In the normal plantlet after 26 weeks of culture, a lot of vessels and companion cells apperaed in the leaf cell of plantlet. In the normal plantlet after 30 weeks of culture, the immature leaf showed many small companion cells, sieve tubes and central vacuole. Also, the secondary vacuole protruded into the central vacuole and elongated chloroplasts near plasma membrane. In the matured plant habituated on the soil, palisada tissue composed of orderly arranged cells contained the nucleus in the center of the cell and large vacuoles on either side of the nucleus.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.10 no.1
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• pp.209-246
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• 1997

In the literatual study on the Ecthyma, the results were as follows. 1. The pathogenic factors of Ecthyma is divided three parts. One is exogenous pathogenic factors which including the wind evil, wind heat and toxic material produced by wetness evil. Another is endogenous pathogenic factors which including the declination of kidney-yang, impairment of the liver and kidney, the lower classes of yin-fire, accumulation of wetness-heat in the spleen asthenia, impairment of the liver and kidney, wetness-heat of three yang, asthenic heat-syndrome of three yin. The other is pathogenic factors neither endogenous nor exogenous which including the food and living, uncontrol sexual excess, anxiety and angry, injury of skin, injury of insects and animals. 2. Five viscera which was concerned with Ecthyma are liver, spleen and kidney. 3. Frequent region of Ecthyma are S-36(足三里) and C-7(陰交). External Ecthyma was rose to wetness-heat of three yang channel that cured easily. Internal Ecthyma was rose to asthenic heat-syndrome of three yin channel that cured hardly. 4. In the frequency of prescription, the most numerous prescription is Bojungikgitang(補中益氣湯) and the next are Kyukgigo(隔紙膏) and Yukmijihwanghwan(六味地滉丸). 5. In the frequency of medicine, the most medicine is Calomelas(輕粉) which included Hydrargyrum(水銀) and the next are Olibanum(乳香) and Resina Commiphorae Myrrhae(沒藥) which regulating vital energy and pain control medicine used that in order to destroy insects and remove polson. 6. In classification of the medical action, medicine of clearing away summer-heat and heat evil and activating blood circulation to dissipate blood stasis used to be very busy which in order to remove the disorder of vital energy for virulent heat-evil. 7. In classification of four characters, the most part is warm medicine, the next are cold and cool medicine and there is a few that is hot medicine. 8. In classification of five tastes, the most numerous tastes are bitter and acrid, the next are sweet, salty and sour tastes. 9. In classification of virulence of medicine, the most part is non-toxic, the next are weakly and deadly poison. 10. In classification of channel distribution, the most is the medicine that belongs to liver channel, the next are the lung, spleen, stomach and kidney channel.

• The Journal of the Korea Contents Association
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• v.14 no.9
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• pp.236-246
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• 2014

Most countries have been promoted the legislative policy for the legal employment, causing a social conflicts by illegal immigrants in any countries. Despite the efforts to alleviate the illegal aliens, there are not nearly enough successful cases, and encounter a social problem about illegal stay worker. China is no exception. At present, the issue of China's foreign illegal employment is expected to be a social problem in the present and the future. However, the legislative policy against immigration control law and illegal foreign employment in China is very neglectful. There is a lack of adjusting rule of law on illegal foreign workers in China, and the remedy is also insufficient. It is necessary to secure a legal right for the protection of the Rights of illegal foreign workers based on the international norms. For this purpose, the illegal foreign workers related law should be enacted, and based on this, administration should be strengthened. The trend of major countries of illegal aliens is centered around an employer hiring strictly regulated. There is a need to have a strengthen regulation on the employer rather than the foreign workers in China. To this end, employer who hire illegal foreign workers should be required to receive considerable disadvantages such as penalties and fines, prison sentences, as well as various kinds of burdens and repatriation costs. It is necessary to run the voluntary repatriation(Freiwillige $R\ddot{u}ckehr$) program of illegal immigrants, and there is a need to take action for illegal immigrants who voluntary return home within a certain period are exempt from penalty. In conclusion, China must push ahead with a direction of positive policy in related ministries rather than sit on its hands on the wrong choice or a confusion of an employer and foreign workers with a policy on illegal foreign residents in limbo.

• Journal of Distribution Science
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• v.12 no.6
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• pp.21-29
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• 2014

Purpose - This research undertakes to understand the competitiveness of the steel distribution industry of both Korea and China to strengthen Korea-Sino economic cooperation, examines impediments to trade between the two countries to analyze causes which affect trade, and examines improvements in these areas to identify means of trade expansion. Through this survey of a defined period, we can identify the structural factors of trade dependence in the relationship between Korea and China. Research design, data, and methodology - The data were collected from the Korea Traders Association, the Korea Customs Office, and UN Comtrade, from which whole table indexes are calculated. The research methodology uses trade-related indexes to focus on analyzing comparative advantages based on time-series analysis statistics data (2000-2012) by using the analysis index of trade intensity index (TII), the revealed comparative advantage index (RCA), and the trade specialization index (TSI). Results - The export ratio for Korea to China was slightly higher in 2000 at 2.867, and the export ratio for Korea to China was sustained in 2005. However, it diminished gradually, reaching 1.263 in 2012. During the period 2000-2012, the indexes were maintained without any significant change. However, they still remain close to -1. In particular, in 2012 it is the closest it has ever been to -1. Therefore, China has a comparative advantage in export specialization. On the other hand, Korea has a comparative advantage in import specialization. For the research period, all indexes were much lower than 1, which means that Korea has consistently had a comparative disadvantage against China for the past 10 years when compared to other industries, even though it experienced improvement in 2000. Conclusions - The summary of conclusions based on empirical analysis research are as follows: First, per the trade intensity index of industries between the two countries, we conclude that the export ratio index in 2000 is 2.867, which means the export ratio of Korea to China is slightly higher. Furthermore, the ratios of 2.259 and 1.263 held in 2005 and 2012, respectively, meaning that the export ratio of Korea to China was maintained in 2005, but was diminishing gradually as the index in 2012 was 1.263. Second, per the trade specialization index of the steel distribution industry between Korea and China, the value was -0.379 in 2000, -0.368 in 2005 and -0.568 in 2012. Looking at the whole period of 2000-2012, the indexes remained without any significant change. However, they are still moving closer to -1. In particular, in 2012 it is the closest it has ever been to -1. Third, regarding the revealed comparative advantage index of the steel distribution industry between Korea and China, the RCA indexes in 2005 and 2012 are 0.246 and 0.306, respectively, which are still far from 1, even though the index has improved compared to the 2000's value of 0.0001. Therefore, the Korean steel distribution industry is at a significant comparative disadvantage to that of the Chinese steel distribution industry.

• Korea Journal of Hospital Management
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• v.22 no.3
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• pp.61-73
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• 2017

Purposes : The purpose of this study is to identify factors that have effects on safety activities of hospital personnels by investigating causality between patient safety culture, job stress, safety system and safety activities of faculty and staff member who are working for oriental medicine hospital of university. Methodology : The subjects were 246 employees working in 4 oriental medicine hospitals of university in Daejeon and Chungcheongnam-do. The data were collected from January 16 to January 25, 2017 using a structured questionnaire. For data analysis, descriptive statistics, Pearson correlation coefficient, t-test, ANOVA and Duncan test with SPSS 22.0 were used. Findings : The activity score for patient safety of faculty and staff member, who were experienced at job training program after joining a company and regular training course for qualification or license, was meaningfully higher than that of group who had no job training experience. The result indicated that the higher there is level of safety culture and safety system and the lower there is work stress, the more the activity has positive effect on patient safety. The level score of awareness for safety culture of faculty and staff member in C hospital, which is facing financial crisis in business circumstances recently, showed average value of 3.29. It was significantly lower than that of the other three hospital. Also, The activity score for patient safety was markedly lower than that of the other three hospital. This result become interested in the process of linking non-financial performance and financial performance. The level score of safety activity in A hospital which obtained healthcare accreditation was remarkably higher than that of the other three hospital which didn't certify healthcare accreditation. Pratical Implications : Subjects about Q.I or patient's experience management must be included in curriculum of Oriental medicine. It is necessary to get the effect of job training program for faculty and staff member through the process of preparation for obtaining healthcare accreditation. When the hospital director is appointed, it must be considered that he/she has the ability to attach importance to analysis and management of the factors creating safety accident, and has business mindset for healthcare delivery of customer- centricity. This research showed that financial performance of hospital, which of business environment is favorable; located in metropolitan city and having large scale of hospital and quality of residence rating but low-level of safety culture and safety activity, was lower than that of general hospital situated in small and medium-sized cities. More research needs to be done for answering this result.

• Genomics & Informatics
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• v.12 no.4
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• pp.240-246
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• 2014

Mutation in HNF1B, the hepatocyte nuclear factor-$1{\beta}$ (HNF-$1{\beta}$) gene, results in maturity-onset diabetes of the young (MODY) 5, which is characterized by gradual impairment of insulin secretion. However, the functional role of HNF-$1{\beta}$ in insulin secretion and glucose metabolism is not fully understood. We identified a family with early-onset diabetes that fulfilled the criteria of MODY. Sanger sequencing revealed that a heterozygous P159L (CCT to CTT in codon 159 in the DNA-binding domain) mutation in HNF1B was segregated according to the affected status. To investigate the functional consequences of this HNF1B mutation, we generated a P159L HNF1B construct. The wild-type and mutant HNF1B constructs were transfected into COS-7 cells in the presence of the promoter sequence of human glucose transporter type 2 (GLUT2). The luciferase reporter assay revealed that P159L HNF1B had decreased transcriptional activity compared to wild-type (p < 0.05). Electrophoretic mobility shift assay showed reduced DNA binding activity of P159L HNF1B. In the MIN6 pancreatic ${\beta}$-cell line, overexpression of the P159L mutant was significantly associated with decreased mRNA levels of GLUT2 compared to wild-type (p < 0.05). However, INS expression was not different between the wild-type and mutant HNF1B constructs. These findings suggests that the impaired insulin secretion in this family with the P159L HNF1B mutation may be related to altered GLUT2 expression in ${\beta}$-cells rather than decreased insulin gene expression. In conclusion, we have identified a Korean family with an HNF1B mutation and characterized its effect on the pathogenesis of diabetes.

• Progress in Medical Physics
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• v.15 no.4
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• pp.237-246
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• 2004

Even though the wedge factor was defined by ICRU, RTPS uses other definition different from the wedge factor to consider the wedge effect to correct dose. Because the factors with different concept are defined in a very different way, replacement of different factor could make severe error of dose and is unacceptable because their values are very different from each other. Radiotherapy machine installed in department includes physical wedges and function of dynamic wedge by upper jaws, and Eclipse and Pinnacle$^{3}$ such as RTPS are used. The wedge factors, relative wedge output factors and wedge field output factors of physical wedges and dynamic wedges were measured by an ionization chamber in water phantom. They are analyzed and compared in according to wedge position, field size, wedge angle, X-ray quality, measurement condition. Wedge factor, relative wedge output factors and wedge field output factors of dynamic wedges comparing physical wedges have an effect of several factors. Main factors effecting to the factors of dynamic wedges were field size and wedge angle. Beam quality of X-ray introduces a few effect to the factors. Because the factors related to wedge and defined with different concepts are different from each other, to reduce dose error it should be input by values proper to RTPS.

• Journal of Digital Convergence
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• v.11 no.9
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• pp.239-246
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• 2013

The purpose of this study was to identify the effects of family resilience on the positive attitudes toward a children with disabilities of non-disabled siblings. For this purpose, a survey data was collected from 110 siblings with disabled children. The general characteristics of the parent questionnaire, and the general characteristics of a child with a disability, non-disability sibling's general characteristics, be receptive attitude, consisted of family resilience, and the data were analyzed by frequency analysis, descriptive statistics, t test, ANOVA and regression analysis by SPSS 18.0. Structural equation was used for black AMOS18. The results of the measurement analysis were summarized as follows: 1. family resilience showed positive correlation with positive attitudes toward a children with disabilities of non-disabled siblings. 2. as a result of regression analysis for find out influence of family resilience on the positive attitude of non-disabled siblings, family resilience was statistically significant influence factors, which 50%, 50% explanatory power. In conclusion, these results reinforce the important of considering family context as a contributor to the positive attitudes toward a children with disabilities of non-disabled siblings, so it could be suggested that family resilience needs to be improve.

• Culinary science and hospitality research
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• v.16 no.4
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• pp.238-246
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• 2010

This study investigates the quality characteristics of soybean dasik made with various levels(0, 3, 6, 9 and 12%) of Platycodon grandiflorum(Jacq.) A. DC. flour additions. In soybean dasik added with Platycodon grandiflortum(Jacq.) A. DC flour, moisture contents range from $24.47{\pm}0.35$ to $26.31{\pm}0.81%$ As Platycodon grandiflorum(Jacq.) A. DC flour increased, lightness values were decreased and redness and yellowness values were increased significantly. The result of the mechanical evaluation showed that hardness increased after significantly decreasing while adhesiveness, gumminess and chewiness decreased with the amount of Platycodon grandiflorum(Jacq.) A. DC flour increased. Cohesiveness and springiness did not change significantly according to Che level of Platycodon grandiflorum(Jacq.) A. DC flour. In conclusion, soybean dasik with the addition of 6% Platycodon grandiflorum(Jacq.) A. DC flour has the most propper taste, flavor and overall acceptability on sensory evaluation.

• Clinical and Experimental Reproductive Medicine
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• v.34 no.2
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• pp.75-85
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• 2007

Objectives: The aim of this study was to find out the attitude of Korean women towards IVF surrogacy which is not yet regulated by the law. Methods: We evaluated with a questionnaire, in how far IVF surrogacy was accepted in different groups of Korean women. Total 300 questionnaires were sent out to women who visited our infertility clinic, and to the nurses and office workers of our hospital. Among them, 246 questionnaires were returned, and 211 of them (85.7%) were complete and analyzed. The responders were 58 unmarried women and 153 married women including 60 infertile patients. Results: Only 17 (8.1%) women believed that IVF surrogacy was an acceptable treatment for infertile women without uterus (eg. MRKH or hysterectomized patients), and 125 (59.2%) women chose the adoption. There were no significant differences in response amongst different age group, marital status, or in relation to income level or educational level, or infertility status. A significantly higher level of acceptance was noted only in religious groups, especially in Christians. Most of responders (66.5%) chose unrelated and unknown women as a desirable host, and 28.4% of responders chose the sister or sister-in-law. Conclusions: Overall the different groups were critical towards IVF Surrogacy in Korea, irrespective of the infertile patient group. Despite the established clinical ability to have her own genetic child in women without uterus, this survey reveals that only minority supports the IVF surrogacy. So we need the survey with large, randomized population and then make a regulation about the IVF surrogacy in law.