• Journal of Cardiovascular Imaging
• /
• v.31 no.3
• /
• pp.145-149
• /
• 2023

BACKGROUND: ¹⁸F-sodium fluoride positron emission tomography/computed tomography (¹⁸F-NaF PET/CT) has been proven to be useful in identification of microcalcifications, which are stimulated by inflammation. Blood speckle imaging (BSI) is a new imaging technology used for tracking the flow of blood cells using transesophageal echocardiography (TEE). We evaluated the relationship between turbulent flow identified by BSI and inflammatory activity of the aortic valve (AV) as indicated by the ¹⁸F-NaF uptake index in moderate aortic stenosis (AS) patients. METHODS: This study enrolled 18 moderate AS patients diagnosed within the past 6 months. BSI within the aortic root was acquired using long-axis view TEE. The duration of laminar flow and the turbulent flow area ratio were calculated by BSI to demonstrate the degree of turbulence. The maximum and mean standardized uptake values (SUVmax, SUVmean) and the total microcalcification burden (TMB) as measured by ¹⁸F-NaF PET/CT were used to demonstrate the degree of inflammatory activity in the AV region. RESULTS: The mean SUVmean, SUVmax, and TMB were 1.90 ± 0.79, 2.60 ± 0.98, and 4.20 ± 2.18 mL, respectively. The mean laminar flow period and the turbulent area ratio were 116.1 ± 61.5 msec and 0.48 ± 0.32. The correlation between SUVmax and turbulent flow area ratio showed the most positive and statistically significant correlation, with a Pearson's correlation coefficient (R²) of 0.658 and a p-value of 0.014. CONCLUSIONS: The high degree of trans-aortic turbulence measured by BSI was correlated with severe AV inflammation.

• Journal of ILASS-Korea
• /
• v.21 no.1
• /
• pp.1-6
• /
• 2016

A gasoline injector rig which can measure cumulative injected fuel mass under a vehicle driving condition was developed. The measurement system consists of an engine control unit (ECU), data acquisition (DAQ) and injected fuel collection system using loadcells. By supplying reconstructed sensor signals which simulate the real vehicle's sensor signals to the ECU, the ECU drives injectors as if they were driven in the vehicle. The vehicle's performance was computer simulated by using $GT-Suite^{(R)}$ software based on both engine part load performance and automatic transmission shift map. Throttle valve position, engine and vehicle speed, air mass flow rate et al. were computer simulated. The used vehicle driving pattern for the simulation was FTP-75 mode. For reconstructing the real vehicle sensor signals which are correspondent to the $GT-Suite^{(R)}$ simulated vehicle's performance, the DAQ systems were used. The injected fuel was collected with mess cylinders. The collected fuel mass in the mess cylinder with elapsed time after starting FTP-75 driving mode was measured using loadcells. The developed method shows highly improved performance in fast timing and accuracy of the cumulative injected fuel mass measurement under the vehicle driven condition.

• Proceedings of the Korean Society of Propulsion Engineers Conference
• /
• 2009.11a
• /
• pp.613-615
• /
• 2009

This paper is to introduce Hanwha Aerospace R&D Center's development status of TVC(Thrust Vector Control) system and control valves for Korean space launch vehicles. With the successful development of KSR-III TVC system, Hanwha have developed TVC system and RCS control valves for KSLV-I. Also, in the advance research area of KSLV-II, Hanwha have participated in LOx and fuel flow control valves and LOx shut-off valve development in the engine supply system. Based on the accumulated experiences and technologies in the aerospace key components and system development, Hanwha will make an important contribution to KSLV-II development in the future.

• Journal of the Korean Society of Radiology
• /
• v.81 no.5
• /
• pp.1151-1163
• /
• 2020

Purpose This study aimed to evaluate changes of subprosthetic pannus on cardiac CT and determine its relationship to echocardiographic findings in patients with mechanical aortic valve replacement (AVR). Materials and Methods Between April 2011 and November 2017, 17 AVR patients (56.8 ± 8.9 years, 12% male) who showed pannus formation on CT and had undergone both follow-up CT and echocardiography were included. The mean interval from AVR to the date of pannus detection was 10.5 ± 7.1 years. In the initial and follow-up CT and echocardiography, the pannus extent and echocardiographic parameters were compared using paired t-tests. The relationship between the opening angle of the prosthetic valve and the pannus extent was evaluated using Pearson correlation analysis. Results The pannus extent was significantly increased on CT (p < 0.05). The peak velocity (3.9 ± 0.8 m/s vs. 4.2 ± 0.8 m/s, p = 0.03) and mean pressure gradient (36.4 ± 15.5 mm Hg vs. 42.1 ± 15.8 mm Hg, p = 0.03) were significantly increased. The mean opening angles of the mechanical aortic leaflets were slightly decreased, but there was no statistical significance (73.1 ± 8.3° vs. 69.4 ± 12.1°, p = 0.12). The opening angle of the prosthetic leaflets was inversely correlated with the pannus extent (r = -0.57, p < 0.001). Conclusion The pannus extent increases over time, increasing transvalvular peak velocity and the pressure gradient. CT can be used to evaluate the pannus extent associated with hemodynamic changes that need to be managed by surgical intervention.

• 한국생물공학회:학술대회논문집
• /
• 2003.10a
• /
• pp.549-553
• /
• 2003

SMB(simulated moving bed) chromatography system has been developed to realize continuous separation and save solvent consumption for binary mixture such as chiral compounds in especial. The parameters of SMB chromatography system can be calculated from mass balance equations of true moving bed chromatography, and they are used in design of 6-column SMB chromatography. We can separate 1'R-25 and 1'S-2S enantiomers as a raffinate product in 95% of purity using assembled SMB chromatography system.

• Journal of Chest Surgery
• /
• v.16 no.3
• /
• pp.337-341
• /
• 1983

The experience with operative treatment for total correction of Tetralogy of Fallot at the department of Thoracic and Cardiovascular Surgery, Korea University Hospital from January, 1977, through April, 1983 was reviewed. Of the 29 patients reviewed, male to female occurrence ratio was 22:7 Type of V.S.D. was type II in 26 cases[90%] and total conus defect in 3 cases[10%]. Average size of V.S.D. was 19 mm. Type of Right ventricular outflow tract stenosis was highest frequency with pulmonary valvular and infundibular stenosis combined type in 21 cases[72%], and there were 8 deaths In this group. Type of R.V.O.T. reconstruction contains 2 cases of infundibulectomy only, 1 case of infundibulectomy with valvular commissurotomy, 2 cases of pericardial patch, 23 Cases of pericardial patch with Teflon or Dacron felt reinforced and 1 case of pulmonary valved conduit reconstruction. Operative mortality was higher in outflow patch through pulmonary valve ring. Overall mortality was 31%. Major causes of death and postoperative complications were low output syndrome, complete A-V block acute renal failure, ventricular fibrillation, bleeding brain abscess, and sudden cardiac arrest.

• Plant Journal
• /
• v.18 no.4
• /
• pp.66-72
• /
• 2023

In order to respond to the demand for flexible operation of thermal power generation, development of natural sliding pressure operation that minimizes throttle loss by opening the turbine control valve 100% and maximize power generation efficiency in conjunction with ESS in order to quickly respond to fluctuations in the system frequency is required. The logic development of natural sliding pressure operation with ESS was developed to modify the existing logic at the power plant's top-level control logic such as the unit master, the boiler master and the turbine master. Cooperative control algorithms that complement the advantages and disadvantages of ESS operation (quick response, limited capacity) and power plant operation (slow response, continuous operation) not only improve efficiency when applied to actual power plants, but also respond quickly and flexibly to load demands to ensure system stability.

• Journal of Chest Surgery
• /
• v.38 no.5 s.250
• /
• pp.382-384
• /
• 2005

Background: It is very difficult to choose the ideal valved conduit used in right ventricle outflow reconstruction in child. We can use the cryopreserved homograft but there is a limit of application because of its difficulties in the size matching and supply capacity. The $Shelhigh^{(R)}$porcine-valved conduit is commercially available and used as an alternative choice in these days. We report two cases of early Shelhigh conduit failure in right ventricular outflow tract after Ross operation in congenital aortic stenosis.

• Transactions of The Korea Fluid Power Systems Society
• /
• v.1 no.4
• /
• pp.1-8
• /
• 2004

The optimum design parameters of several hydraulic systems are obtained using the complex method that is one kind of constrained direct search method. First, the parameters of lead-lag controller of the direct drive servovalve is designed using the complex method to satisfy the steady-state error requirement. Second, the optimum locating point of hydraulic cylinder Is determined to minimize the cylinder force in the operation range of rotational sluice gate. For the third application case, the optimum piston area of hydraulic cylinder is determined to minimize the man power to elevate the manually operated sluice gate.

• Proceedings of the SAREK Conference
• /
• 2008.11a
• /
• pp.381-386
• /
• 2008

In this study, the energy characteristic of automatic thermostatic valves according to each heating method in floor radiant heating system were researched by computer simulation. For the analysis of unsteady heat transfer phenomena in household, the method of using electrical equivalent R-C circuit is applied, and radiation heat transfer between panel, ceiling and walls in household is calculated by enclosure analysis method. The parametric study on heating method, valve's control method, outdoor air condition, supply heating water temperature, supply flow rate are performed to compare energy characteristic, respectively.