• BMB Reports
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• 제33권3호
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• pp.279-284
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• 2000

Using fluorescence probes, 2-(9-anthroyloxy) stearic acid (2- AS) and 12-(9-anthroyloxy) stearic acid (12-AS), we determined the differential effects of local anesthetics (tetracaine-HCI, bupivacaine-HCI, lidocaine-HCI, prilocaine-HCI and procaine-HCI) on the differential rotational rate between the surface (in carbon number 2 and its surroundings including the head group) and the hydrocarbon interior (in carbon number 12 and its surroundings) of the outer monolayer of the total phospholipid fraction liposome that is extracted from synaptosomal plasma membrane vesicles. The anisotropy (r) values for the hydrocarbon interior and the surface region of the liposome outer monolayer were$0.051{\pm}0.001$ and $0.096{\pm}0.001,$ respectively. This means that the rate of rotational mobility in the hydrocarbon interior is faster than that of the surface region. Local anesthetics in a dosedependent manner decreased the anisotropy of 12-AS in the hydrocarbon interior of the liposome outer monolayer, but increased the anisotropy of 2-AS in the surface region of the monolayer. These results indicate that local anesthetics have significant disordering effects on the hydrocarbon interior, but have significant ordering effects on the surface region of the liposome outer monolayer.

• The Korean Journal of Physiology and Pharmacology
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• 제4권1호
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• pp.41-46
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• 2000

Using fluorescence polarization of 12-(9-anthroyloxy)stearic acid (12-AS) and 2-(9-anthroyloxy)stearic acid (2-AS), we evaluated the differential effects of local anesthetics on differential rotational rate between the surface (in carbon number 2 and its surroundings including the head group) and the hydrocarbon interior (in carbon number 12 and its surroundings) of the outer monolayer of the total lipid fraction liposome extracted from synaptosomal plasma membrane vesicles. The anisotropy (r) values for the hydrocarbon interior and the surface region of the liposome outer monolayer were $0.078{\pm}0.001$ and $0.114{\pm}0.001,$ respectively. This means that the rate of rotational mobility in the hydrocarbon interior is faster than that of the surface region. In a dose-dependent manner, the local anesthetics decreased the anisotropy of 12-AS in the hydrocarbon interior of the liposome outer monolayer but increased the anisotropy of 2-AS in the surface region of the monolayer. These results indicate that local anesthetics have significant disordering effects on the hydrocarbon interior but have significant ordering effects on the surface region of the liposome outer monolayer.

• 한국유체기계학회 논문집
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• 제13권1호
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• pp.23-28
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• 2010

A draft tube which has impeller to elevate bottom water and spread it over surface of lake water, induces convective circulation of lake water, a Long-Distance Circulation (LDC). Circulation of lake water make stratified water mixed and enhance DO (Dissolved Oxygen) of bottom water. Circulation rate of water is determined by draft rate of the tube, which is dependent on design parameters of the draft tube system, i. e. dimension of impeller and diffuser, inclined angle of impeller, impeller shape, and rotational speed. In this study, change in draft rate and power consumption of circulation equipment was investigated numerically with changing impeller dimension, angle and rotational speed. It was found that flowrate of draft water was increased as the dimensions of draft tube and impeller, and rotational speed and inclined angle of impeller increased. The power consumption was also elevated with increasing parameter values, and final selection of parameter values was made to satisfy target flowrates and power consumption.

• Design & Manufacturing
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• 제17권2호
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• pp.15-21
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• 2023

In this study, a diamond turning machine and a laser-assisted machining module were utilized for the complex combined cutting of aspheric shapes and fine patterns on the surface of high-hardness brittle material, silicon. The analysis of material's form accuracy and corrective machining was conducted based on key factors such as laser output, rotational speed, feed rate, and cutting depth to achieve form accuracy below 1 ㎛ and surface roughness below 0.1 ㎛. The cutting condition and corrective machining methods were investigated to achieve the desired form accuracy and surface roughness. The rotational speed of the spindle and the linear feed rate of the diamond turning machine were varied in five stages for the cutting condition test. Surface roughness and form accuracy were measured using both a contact surface profilometer and a non-contact surface profilometer. The experimental results revealed a tendency of improved surface roughness with increased rotational speed of the workpiece, and the best surface roughness and form accuracy were observed at a feed rate of 5 mm/min. Furthermore, based on the cutting condition experiments, corrective machining was performed. The experimental results demonstrated an improvement in form accuracy from 0.94 ㎛ to 0.31 ㎛ and a significant reduction in the average value of the surface roughness curve from 0.234 ㎛ to 0.061 ㎛. This research serves as a foundation for future studies focusing on the machinability in relation to laser output parameters.

• 한국정밀공학회지
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• 제19권2호
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• pp.187-194
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• 2002

For the fine grinding process development of semiconductor monocrystalline silicon, wheel rotational speed, chuck rotational speed, feed rate and hysteresis force were controlled. Magic mirror system was used for grinding wheel pattern analysis. Curvature of wheel pattern was measured by fitting equation. The modeling of surface wheel pattern was related to wheel and chuck rotational speed. The calculated curvature of the model was well matched with the measured curvature. The statistical analysis indicated wheel and chuck rotational speed were significantly effective on.

• 대한기계학회논문집B
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• 제38권1호
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• pp.95-101
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• 2014

본 연구는 고속 회전형(~10,000 rpm) 기어펌프의 질량유량과 효율을 예측하기 위해서 2 차원 immersed solid method(ISM)를 이용한 수치해석을 수행하였다. 기어펌프와 하우징의 순환유동을 고려하기 위하여 유체 유동을 난류 유동으로 가정하였고, 기어 펌프의 입 출구의 일정 압력 조건하에 기어펌프의 회전 속도를 부가하였다. 기어펌프의 다양한 회전 속도 및 기어 끝 단과 하우징 사의의 서로 다른 간극에 대한 질량유량 및 효율을 검토하였다. 해석 결과로서, 회전 속도가 증가할수록 평균 질량유량 및 효율은 증가하였고, 기어펌프와 하우징의 간격이 증가할수록 평균 질량유량 및 효율은 감소하였다. 간격이 없는 조건하의 6,000 rpm, 8,000 rpm, 10,000 rpm 회전속도에의 효율은 각각 85.11 %, 90.94 %, 93.62 % 를 얻었고, 간격이 0 m, 0.00001 m, 0.00003 m 에 대해서 효율은 각각 93.62 %, 93.29 %, 92.74 % 를 얻었다.

• 한국산학기술학회논문지
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• 제18권2호
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• pp.31-37
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• 2017

본 연구는 오존 방식 선박평형수 처리의 주요 장치인 기체-액체 이젝터에 대하여 구동 노즐의 유입부에 회전 운동 유도 장치에 의해 발생되는 구동 유체의 회전 운동이 이젝터 효율에 미치는 영향에 관한 연구이다. 먼저 배압에 따른 이젝터의 각 포트별 압력과 흡입 유량을 확인하기 위하여 실험 장치를 구성하고, 회전 운동이 없는 이젝터에 대한 실험 수행 및 데이터를 획득한다. 실험의 데이터를 바탕으로 격자 사이즈 비교를 통해 기체-액체 이젝터에 적합한 유한요소모델을 선정하였으며, 도출된 CFD 모델을 이용하여 구동 유체의 회전 운동이 이젝터의 흡입 효율을 향상시킬 수 있음을 확인하였다. 이를 바탕으로 이젝터의 흡입 유량을 높이기 위하여, 메타 모델을 이용한 크리깅 기법을 사용하여 회전 유도 장치의 내부 형상 인자인 전체 길이 l, 내부 직경 d, 날개 개수 n에 대한 구조 최적화를 수행한다. 최적화된 회전 유도 장치를 적용한 결과 구동 유체의 회전 운동이 없는 이젝터에 비해 이젝터 효율이 약 3% 가량 개선됨을 확인하였다.

• 대한방사선기술학회지:방사선기술과학
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• 제46권1호
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• pp.9-14
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• 2023

When measuring cerebrovascular with 3D rotational angiography, the accuracy was verified by comparing the actual size and measurement size, respectively. It is intended to help select therapeutic materials and instruments during cerebrovascular intervention by comparing the average error rates for measured values in the 3DRA and CTA methods by examining with protocols such as brain CTA, which are always performed in emergency situations. The mean error rate between the groups of measurers was ±3.655% for radiation technologist and ±3.331% for university students, and the mean error rate of the student group was within tolerance (±10%), and the independent sample T-test result t =0.879, p=0.394 (p>0.05) showed no statistically difference between the two. In addition, the average error rate measured by both groups by 3DRA was measured below ±5% within the tolerance error rate (±10%), and most of CTA was measured within the tolerance range (±10%), but showed an average error rate of up to 5.65%, and the independent sample T-test result was statistically more accurate than 3DRA. Both the 3DRA method and the brain CTA method for measuring cerebrovascular size could be accurately measured within tolerance, but it would be better to measure cerebrovascular blood vessels using a more accurate 3DRA method during cerebrovascular intervention.

• The Korean Journal of Physiology and Pharmacology
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• 제7권3호
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• pp.125-130
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• 2003

The aim of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Fluorescence polarization of n-(9-anthroyloxy)stearic acid was used to examine the effect of chlorhexidine digluconate on differential rotational mobility of different positions of the number of membrane bilayer phospholipid carbon atoms. The six membrane components differed with respect to 2, 3, 6, 9, 12, and 16-(9-anthroyloxy)stearic acid (2-AS, 3-AS, 6-AS, 9-AS, 12-AS and 16-AP) probes, indicating different membrane fluidity. Chlorhexidine digluconate increased the rate of rotational mobility of hydrocarbon interior of the cultured Porphyromonas gingivalis outer membranes (OPG) in a dose-dependent manner, but decreased the mobility of surface region (membrane interface) of the OPG. Disordering or ordering effects of chlorhexidine digluconate on membrane lipids may be responsible for some, but not all of its bacteriostatic and bactericidal actions.

• 대한치과기공학회지
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• 제35권4호
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• pp.295-302
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• 2013

Purpose: The grindability of Ti-10%Zr-X%Cr(X=0,1,3) alloys in order to develop Ti alloys for dental applications with better machinability than unalloyed titanium has been evaluated. Methods: Experimental Ti-10%Zr-X%Cr(X=0,1,3) alloys were made in an argon-arc melting furnace. Slabs of experimental alloys were ground using a SiC abrasive wheel on an electric handpiece at one of the four rotational speeds of the wheel (12000, 18000, 25000 or 30000rpm) by applying a force(100gf). Grindability was evaluated by measuring the amount of metal volume removed per minute(grinding rate) and the volume ratio of metal removed compared to the wheel material lost, which was calculated from the diameter loss (grinding ratio). Experimental datas were compared the results with those of cp-Ti(commercially pure titanium) Results: It was observed that the grindability of Ti-10%Zr-X%Cr(X=0,1,3) alloys increased with an increase in the Cr concentration. More, they are higher than cp-Ti, particularly the Ti-10%Zr-3%Cr alloy exhibited the highest grindability at all rotational speeds except 12000rpm. There was significant difference in the grinding rate and grinding ratio between Ti-10%Zr-3%Cr alloy and cp-Ti at all rotational speeds(p<0.05). Conclusion: The Ti-10%Zr-3%Cr alloy exhibited better grindability at high rotational speeds, great potential for use as a dental machining alloy.