• Journal of Ecology and Environment
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• 제29권3호
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• pp.305-321
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• 2006

대기 산성 강하물 : 삼림의 질소 포화 한국의 연평균 습성 질소 강하량은 12.78(범위: $7.28{\sim}21.05)\;kgN{\cdot}ha^{-1}{\cdot}yr^{-1}$이고, 이것에 건성 질소 강하량(43%)을 합하여 추정한 총질소 강하량은 18.26(10.41-30.10) $kgN{\cdot}ha^{-1}{\cdot}yr^{-1}$이 된다. 이 질소 강하량은 유럽과 북미 북동부의 질소 강하량과 비슷한 수준이다. 대기 질소 강하량이 많은 온대 삼림은 질소로 포화된다. 질소로 포화된 삼림은 계류수와 토양에 질산이온 ($NO_3^-$)과 질산태질소/암모늄태질소이($NO_{3}^{-}-N/NH_{4}^{+}-N$)의 비가 높아지고, 잎의 질소 농도가 높아지므로 N/P비, N/K비 및 N/Mg 비가 높아지는 것으로 보아 무기 영양소 교란이 일어나며, 상해와 병해에 걸리기 쉬워지고 세근과 근균의 활성이 낮아짐으로써 생산성이 낮아진다. 그러고 혐질소성 종이 호질소성 종에 의하여 대치된다. 질소로 포화된 토양에서는 온실가스인 메탄($CH_4$)의 흡수가 감소되고 일산화질소 (NO)와 아산화질소 ($N_{2}O$)의 배출이 증가되어 지구온난화를 촉진할 수 있다. 이 종설은 한국의 33장소에서 6년 동안 ($1999{\sim}2004$) 측정한 부피가중 연평균 습성 질소 강하량이 삼림의 질소 포화 수준에 달하고, 광릉시험림분수계와 그 밖의 삼림 계류수의 $NO_3$ 유출량으로 미루어 보아 한국의 삼림에 질소 포화의 징후가 나타났음을 제시하며, 문헌 자료를 통해서 외국의 삼림에서 일어나는 질소 포화의 징후를 체계적으로 논하는 데 목적이 있다.

• Journal of Periodontal and Implant Science
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• 제25권3호
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• pp.529-538
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• 1995

It has been believed that the increased release of free oxygen radicals ($O_2^-,H_2O_2$, and $OH^-$) might be a factor in the pathogenesis of periodontal diseases. Antioxidant enzymes such as glutathione peroxidase(GSH-PX) and catalase can protect the tissue damage from the $H_2O_2$. In order to investigate the GSH-PX and catalase activity in the blood plasma and red blood cells(RBCs) of the patients with periodontitis, 19 patients who had good general health, attachment loss more than 6 mm and bone loss were selected as periodontitis group, 7 patients who had severely inflamed gingiva were selected as gingivitis group, and 15 volunteers with good general and periodontal health were selected as normal group. 17 of 26 patients were performed scaling and root planing to reduce the gingival inflammation for gingivitis and periodontitis groups, and were selected as posttreatment group. After blood plasma and RBCs were collected and separated 1 ml of peripheral blood from each subject, GSH-PX activity in blood plasma and RBCs was measured by the same method that Stefan et al. did, and catalase activity in RBCs was measured by the same method that Beers et al. did. The difference of GSH-PX and catalase activity between normal, gingivitis, and periodontitis groups was statistically analyzed by ANOVA with SPSS/PC+ program, and the difference between pretreatment and posttreatment groups was analyzed by Student t-test. The results were as follows : 1. GSH-PX activity in blood plasma was significantly lower in the gingivitis group($0.8683{\pm}0.0658$), periodontitis group($0.7130{\pm}0.1333$) than in the normal group($1.0241{\pm}0.0801$)(p<0.05), and GSH-PX activity in RBCs was significantly lower in the gingivitis groupt. $0.8156{\pm}0.1167$), periodontitis group($0.7533{\pm}0.1185$) than in the normal group($l.1963{\pm}0.2044$)(P<0.05), but there was no statistical significance in the difference of GSH-PX activity in RBCs between the gingivitis group and periodontitis group(p>0.05). 2. Catalase activity in RBCs was siginficantly lower in the periodontitis group($117.34{\pm}35.01$) than in the normal group($l52.38{\pm}32.09$)(p<0.05). 3. GSH-PX activity in blood plasma was significantly increased in the posttreatment groupe $1.0376{\pm}0.2820$) compared to the pretreatment group(0.7608 0.1600) (p<0.05), and GSH-PX activity in RBC was significantly increased in the posttreatment group($1.0421{\pm}0.2330$) compared to the pretreatment group($0.7728{\pm}0.1210$)(p<0.05). 4. There was no statistical significance in the difference of catalase activity in RBCs between the pretreatment group($112.04{\pm}43.65$) and posttreatment group($l33.41{\pm}39.16$)(p>0.05).The results, within the limits of the present experiment, suggest that the lowered activity of GSH-PX and catalase in blood plasma and RBCs may be related with periodontopathogenesis.

• 대한한방내과학회지
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• 제33권2호
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• pp.126-144
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• 2012

Background : Peripheral nerves more rapidly recover than central nerves. However, it has been known that the degree of reaction of axons of peripheral nerves is affected by distinctive characteristics of axons and environmental factors near the axons. Taxol is a widely used medicine as for ovarian, breast, lung and gastric cancer. However it causes patients difficulties under treatment due to its toxic and side effects, which include persistent pain. Objectives : This study reviewed how SJT extract in vitro and in vivo affects nerve tissues of a sciatic nerve damaged by Taxol. It also studied how SJT extract in vivo affects axons of the sciatic nerve after the sciatic nerve was damaged by pressing. Methods : After vehicle, Taxol, and Taxol plus SJT were treated respectively for tissue of the sciatic nerve in vitro and then tissues were observed using Neurofilament 200, Hoechst, ${\beta}$-tubulin, $S100{\beta}$, caspase-3 and anti-cdc2. SJT was also oral medicated by injecting Taxol into the sciatic nerve of in vivo rats. Tissues of the sciatic nerve and axons of DRG sensory nerves were then observed using Neurofilament 200, Hoechst, ${\beta}$-tubulin, $S100{\beta}$, caspase-3 and p-Erk1/2. After inflicting pressing damage to the sciatic nerve of in vivo rats, tissues of the sciatic nerve and DRG sensory nerve were observed using Neurofilament 200, Hoechst, $S100{\beta}$, caspase-3, anti-cdc2, phospho-vimentin, ${\beta}1$-integrin, Dil reverse tracking and p-Erk1/2. Results : The group of in vitro Taxol plus SJT treatment had meaningful effects after sciatic nerve tissue was damaged by Taxol. The group of in vivo SJT treatment had effects of regenerating Schwann cells and axons which were damaged by Taxol treatment. The group of in vivo SJT had effects of regenerating axons in damaged areas after the sciatic nerve was damaged by pressing, and also had variations of distribution in Schwann cells at DRG sensory nerves and axons. Conclusions : This study confirmed that SJT treatment is effective for growth of axons in the sciatic nerve tissues and improvement of Schwann cells after axons of the sciatic nerve tissues was damaged. After tissues of sciatic nerve was damaged by pressing in vivo, SJT treatment had effects on promoting regeneration of axon in the damaged area and reactional capabilities in axons of DRG sensory nerves.

• 아시안잔디학회지
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• 제23권1호
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• pp.123-132
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• 2009

본 연구는 2007년 늦가을에서 2008년 초봄까지 골프코스 그린에서 스키 슬로프로 전환하기 전, 적설 및 제설 시기를 다르게 실시한 4개 시험구에 메틸렌 유레아(MU), 복합 화학비료(CF), 입상 휴믹산 비료(HM), 동물성 유기질 비료(NS)를 처리하여 늦가을 시비가 이듬해 봄철 bentgrass의 greenup에 미치는 영향을 분석하였다. 적설 10일전에 MU와 입상 휴믹산 비료인 입상 휴믹산 비료가 이듬해 봄에 전체적으로 가장 빠른 시각적 품질 상태와 녹색도를 보였다. 공시 비료 중 인산($P_2O_5$)함량이 가장 높은 CF는 봄철 뿌리 신장에 가장효과적이어서 골프코스로 전환 시점(4월 3일)에는 뿌리길이가 평균 13.0cm로 측정되었다. 하지만 CF처리 후 바로 적설된 시험구에서 시각적 품질과 녹색 도에서 가장 낮은 결과를 보여 최소 적설 10일 전에 시비하여야 적설에 의해 용해되지 않았던 잔류 비해를 피할 수 있는 것으로 나타났다. 동물성 유기질 비료의 시비는 적설처리하지 않았던 시험구에서는 잎의 건물 중이 가장 높았으나 무시비구와 봄철 녹색도 및 시각적 품질평가에서 차이를 보이지 않았다. 따라서 골프코스에서 스키슬로프로 전환하기 위한 적설 시기와 골프 코스로의 재 전환을 위한 적절한 늦가을 시비관리 및 제설 시기는 이듬해 봄철 bentgrass의 greenup과 잔디 생육을 위한 중요한 요소로 분석 되었다.

• 대한관절경학회지
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• 제11권2호
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• pp.128-133
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• 2007

목적: 내측 반월상 연골 방사형 파열의 관절경적 연골판 절제술 후 임상 결과를 알아 보고자 하였다. 대상 및 방법: 내측 반월상 연골 방사형 파열을 가진 2년 이상($2{\sim}7$년)의 추적이 가능하였던 45례를 대상으로 하였다. 관절경 수술은 체중 부하 단순 방사선 사진에서 Kellgren과 Lawrence분류상 정상이나 초기 퇴행성 관절염(0-2군)으로 분류된 환자에 한하여 시행하였다. 연골 손상의 정도는 수술 중에 Outerbridge 분류를 사용하였으며, 임상적 결론은 Modified Lysholm score를 사용하였다. 결과: 술 전 평균 Lysholm점수는 위의 순서대로 79.1, 71.2, 68.5, 67.9, 67.2, 61.5 이였으며, 술 후 점수는 86.3, 75.1, 73.0, 73.1, 73.2, 66.2이였다. 술 후 통증 호전은 각각 61.5%, 62.5%, 60.0%, 50.0%, 50.0%, 25.0%이었고, 술 후 만족도는 69.2%, 75.5%, 70.0%, 66.6%, 75.0%, 75.0%이었으며, 30.7%, 25.0%, 20.0%, 50.0%, 25.0%, 50.0%에서 다시 수술을 해야 할 것으로 대답하였다. 추시 단순방사선 사진은 7례(15.5%)에서 Kellgren과 Lawrence분류상 3군의 퇴행성 관절염으로 전환되었다. 결론: 단순 방사선 사진에서 정상 이나 초기 퇴행성 관절염을 가진 군(Grade 0-2)에서 내측 반월상 연골 방사형 파열은 다른 형태의 파열과는 달리 관절경적 절제술 후 불량한 임상적 결과를 보였다. 우수한 결과를 위해서는 관절경적 절제술 보다는 긴장 장력을 복원하는 술식이나 퇴행성 관절염을 방지 할 수 있는 근위 경골 절골술 등이 고려되어야 한다.

• Journal of Plant Biology
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• 제12권3호
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• pp.15-25
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• 1969

To investigate the radiation effect of P-32 on the soybean plants, the seeds treated with various levels of P-32 solution were sown and cultured in the pots. The growth of the plants and the contents of the macroelements were observed and the following results were obtained. 1) The linear growth of the plants at the early stage seemed to have been promoted by the low-level P-32 treatemnt. At the later growing stage, however, this difference among treatments were less conspicuous. 2) The plants of high level P-32 application showed some growth damaging symptom at the early growing stage. Later this damage was recorded as the time went on and these plants showed even better growth than the control. As a result at the late growing stage, they ensued highest growth. 3) The plants showed in general more growth at the low activity level than at the high-level at the early growing stage. At the late stage, however, the high-level activity promoted more growth than the low-level. 4) At the early growing stage P-32 treatment produced in general significantly more lower than control. At the later stage, however, this difference was not clearly seen. 5) The P-32 treatment seemed to have stimulated earlier florescence and this tendency was more clearly observable eapecially at the high activity level. 6) The weight of the air-dried seeds tended to be increased through P-32 treatment by 10-45%. This tendency was clearly observed especially at the low-level activity. 7) As for the contents of the various macroelements in the leaves, the nitrogen showed significantly larger contents at the middle level(S1) P-32 treatments. The phosphorous contents showed also highest at the middle levels activity and lower both at the high and low-activity levels. The potassium contents was proved, on the contrary, higher at the low-level activity and lower at the high-level. 8) The nitrogen contents in the stems was found significantly higher than control, except at the low-activity level. The phosphorous showed higher contents at the low-activity level and no significant difference at the high-activity level. As for the contents of potassium, calcium and magnesium, three seemed no significant difference among treatments. However, the magnesium showed somewhat higher content at the low-activity level, whereas the calcium was proved high than control. 9) The inorganic contents in the root showed that N and P in the P-32 treated plant were significantly higher than the control and the K-contents was, on the contrary, significantly higher at the control than the rest of the treatments. As for the calcium and magnesium there showed no difference among all treatments.

• The Plant Pathology Journal
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• 제23권3호
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• pp.174-179
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• 2007

Seedlot disinfection techniques to control mung bean sprout rot caused by Colletoricum acutatum and C. gloeosporioides were evaluated for commercial production scheme. Soaking seedlots in propolis (100 X) and ethanol (20% for 30 min) appeared promising with control values of 85.5 and 80.8 respectively, but still resulted in up to 20% rot incidence. None of the C. acutatum conidia survived through hot water immersion treatment (HWT) for 10 min at temperatures of 55, 60 and $65^{\circ}C$, whereas the effective range of the dry heat treatment (DHT) was $60-65^{\circ}C$. Tolerance of mung bean seedlot, as estimated by hypocotyl elongation and root growth, was lower for HWT than for DHT. Germination and growth of sprouts were excellent over the range of $55-65^{\circ}C\;at\;5^{\circ}C$ intervals, except for HWT at $65^{\circ}C$ for 5 min. At this marginal condition, heat damage appeared so that approximately 2% of seeds failed to sprout to normal germling and retarded sprouts were less than 5% with coarse wrinkled hypocotyls. These results suggested that DHT would be more feasible to disinfect mung bean seedlots for commercial sprout production. Heat treatment at above ranges was highly effective in eliminating the epiphytic bacterial strains associated with marketed sprout rot samples. HWT of seedlot at 55 and $60^{\circ}C$ for 5 min resulted in successful control of mung bean sprout rot incidence with marketable sprout quality. DHT at 60 and $65^{\circ}C$ for 30 min also gave good results through the small-scale sprouting system. Therefore, we optimized DHT scheme at 60 and $65^{\circ}C$ for 30 min, considering the practical value of seedlot disinfection with high precision and accuracy. This was further proved to be a feasible and reliable method against anthracnose incidence and those bacterial strains associated with marketed sprout rot samples as well, through factory scale mung bean sprout production system.

• 대한소아치과학회지
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• 제29권4호
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• pp.555-560
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• 2002

완전탈구된 치아의 치료법은 재식술을 들 수 있는데, 이는 치조와에서 이탈된 치아를 가능한 빠른 시간 내에 재식립하는 술식이다. 일반적으로 재식술의 성공여부는 치수와 치주인대 손상의 정도, 치아상실 시부터 치조와 내로 재식될 때까지의 경과시간, 탈구된 치아의 보관 상태, 치근의 발육 정도 등에 좌우된다. 그 중 치아상실 시부터 재식까지의 경과시간이 특히 중요한데, 일반적으로 30분 이내에 재식을 시행한 경우에는 90%이상의 성공률을 보인 반면 30분에서 90분 사이에서는 43%, 90분 이상 경과 시에는 7%의 성공률을 보인다고 알려져 있다. 본 증례는 완전탈구 후 오랜 시간이 지연되어 재식을 시행하였으나 치근유착을 통해 비교적 양호한 임상적 결과를 얻었다. 이러한 치료로 결국은 치아의 손실이 일어날지 라도, 이것은 환자 및 보호자의 사고에 따른 충격을 감소시켜주고, 자체로 공간 유지장치로서의 기능을 할 수 있으며, 발치에 따른 치조골의 흡수를 늦추는 한편, 적극적인 보철치료를 위한 시간을 벌어줄 수 있을 것으로 사료된다.

• 대한본초학회지
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• 제31권4호
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• pp.101-109
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• 2016

Objectives : HT070 is a mixture of herbal extracts from root of Scutellaria baicalensis and stem bark of Eleutherococcus senticosus , which have long been used for stroke therapy in traditional Korean Medicine. The purpose of this study was to investigate the neuroprotective effects of HT070 on global cerebral ischemia and its potential mechanisms.Methods : Transient global cerebral ischemia was produced by 10 min of four-vessel occlusion (4-VO) in male Wistar rats. HT070 was administered orally at a dosage of 200 mg/kg twice at 0 and 90 min after reperfusion. Hippocampal neuronal damage was measured 7 days after reperfusion. To explore the potential mechanisms, we used hydrogen peroxide (H₂O₂)-induced rat pheochromocytoma (PC12) cells as an in vitro model. PC12 cells were pretreated with HT070 for 1 h and then exposed to 100 μM H₂O₂ for 6 h in the presence of HT070. Cell viability was measured by MTT assay and the mRNA expression of Bax, Bcl-2, iNOS and COX-2 were measured by quantitative RT-PCR.Results : Oral administration of HT070 at a dose of 200 mg/kg significantly reduced neuronal death in the hippocampal CA1 region by 13.4% as compared to the vehicle-treated group. HT070 increased cell viability, reversed the down-regulated Bcl-2 mRNA level, and suppressed the up-regulated mRNA expressions of Bax, iNOS, and COX-2 in H₂O₂-treated PC12 cells.Conclusions : HT070 protects against delayed neuronal death after global cerebral ischemia and its neuroprotection properties might be attributed to the inhibition of mitochondrial apoptosis and ROS-generating enzymes.

• 대한토목학회논문집
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• 제38권2호
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• pp.215-226
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• 2018

본 연구에서는 도시지역 관망 내 수위 관측자료를 이용하여 도시지역 유출해석 및 관망해석의 정확도를 높이고자 한다. 이를 위해 도시유출해석의 주요 매개변수별 민감도 분석을 수행하고, 매개변수의 보정을 수행하였다. 매개변수의 민감도는 관의 조도계수, 불투수지역의 조도계수, 유역폭, 투수지역의 조도계수 순으로 나타났다. 민감도가 높은 4개의 매개변수를 이용하여 매개변수 고려 개수와 종류에 따라 6가지 시나리오를 구성하였으며, 자동보정기법인 PEST를 도시유출 모형인 SWMM과 연계 해석하여 분석하였다. 각 조건을 2013년 7월 21일 집중호우로 인하여 침수피해가 발생한 서초3, 4, 5, 역삼, 논현 배수분구에 적용하였다. 민감도 결과를 이용하여 시나리오별 분석을 실시하였을 때 SWMM 모형만을 이용하였을 때 보다 불확실성이 줄어든 결과를 보였다. 모의결과 RMSE는 최대 2.41cm가 감소하였으며, 상대첨두오차는 13.7%가 감소하였다. 민감도가 낮은 투수지역의 지표면 조도계수를 고려한 시나리오의 경우가 고려하지 않은 시나리오의 경우보다 정확도가 소폭 낮아졌으며 계산시간도 많이 소요되었다. 본 연구 결과 대상 유역에 대한 민감도 분석 후 민감도가 높은 매개변수만을 고려하여 시나리오를 구성하였을 때 보다 효율적인 모의가 될 수 있다는 것을 알 수 있었으며 향후 추가적인 강우사상과 침수해석을 연계할 시에는 도시지역의 침수예경보 연구에 기여할 수 있을 것으로 판단된다.