• Journal of Fashion Business
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• v.23 no.6
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• pp.37-48
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• 2019

This paper aims to stretch the technology acceptance model (TAM) approach by investigating a clothes rental network. One of the understudied geographies of the world economy is the large-scale international trade in clothes, which are consumed by Chinese consumers. An online (www.sojump.com) survey was conducted by including 303 Chinese respondents. Structural equation modeling (SEM) was used to test the proposed hypothesis. The results indicated that external influence has a significant impact on the perceived ease of rental. Furthermore, consumers' perceived ease of rental influences the attitude towards renting, and perceived ease of rental plays a complete mediating role between them. However, external influence has no significant impact on perceived usefulness, and consumers' perceived usefulness has no impact on rental intention. In addition, attitude towards renting works as an indispensable mediation between perception and behavior. This study highlights the role of perception, attitude, behavior on clothes rental, and provides guidance and suggestions for clothes rental platform.

• Proceeding of EDISON Challenge
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• 2013.04a
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• pp.13-24
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• 2013

Dopamine agonists and antagonists and its receptor play a critical role in the information transfer in the nervous system, and dopamine receptor-ligands interactions are deeply related to Parkinson's disease, schizophrenia and some other mental diseases. However, the only experimental 3D structure available for dopamine receptors is human D3 dopamine receptor. Therefore, it is important to create model of subtype dopamine receptor-ligands interactions. We report here the 3D structures of the human D1 and D2 dopamine receptor predicted by using GalaxyTBM, and its predicted binding site determined by using GalaxyDock. The highly conserved Asp on TM 3 and Phe on TM 6 have critical role in ligand binding. Also, highly conserved serines on TM 5 are essential for binding agonists and some kinds of antagonists. We identify differences between binding sites of agonists and antagonists of human D1 and D2 dopamine receptor, and find the reasons of selective binding of antagonists.

• Journal of Integrative Natural Science
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• v.9 no.1
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• pp.35-40
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• 2016

Protein phosphatase manganese dependent 1D (PPM1D) is one of the Ser/Thr protein phosphatases belongs to the PP2C family. They play an important role in cancer tumorigenesis of various tumors including neuroblastoma, pancreatic adenocarcinoma, medulloblastoma, breast cancer, prostate cancer and ovarian cancer. Even though PPM1D is involved in the pathophysiology of various tumors, the three dimensional protein structure is still unknown. Hence in the present study, homology modelling of PPM1D was performed. 20 different models were modelled using single- and multiple-template based homology modelling and validated using different techniques. Best models were selected based on the validation. Three models were selected and found to have similar structures. The predicted models may be useful as a tool in studying the pathophysiological role of PPM1D.

• Asian Journal of Innovation and Policy
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• v.8 no.2
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• pp.238-273
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• 2019

Social enterprises pursue innovation to create socio-economic impact for the marginalized communities. The founders of social enterprises drive goal-oriented innovation, whereas, interactions with ecosystem is crucial to create and diffuse innovation. However, studies are scant on creation as well as diffusion of innovation emerging from social enterprises. This paper attempts to understand innovation emerging from social enterprises through an exploration of innovation focus, interactions with ecosystem, and measurement of innovation performance. A cross-sectional study is performed to understand the relationship between founders' orientation and innovation performance, and the mediating role of innovation focus and ecosystem interactions. A cluster sampling across four states in India - Karnataka, Telangana, Maharastra and Tamil Nadu - resulted in participation from 207 social enterprises. The results of partial least squared structural equation modeling (PLS-SEM) demonstrate the positive complementary mediating role of innovation focus in the relationship between founders' orientation and innovation performance. Moreover, this paper illustrates that founders' persistent focus on innovation creates positive results for social enterprises as well as beneficiaries.

• Safety and Health at Work
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• v.14 no.1
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• pp.78-84
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• 2023

Background: Since the advent of the COVID-19 pandemic, physicians have been the unsung heroes of the pandemic. However, many are about to give up the battlefield. This study investigated the effect of occupational moral injury on physicians' career abandonment intention, taking into account the possible mediating role of emotional exhaustion. Methods: Cross-sectional data collected from 201 physicians were analyzed using the partial least squares structural equation modeling (PLS-SEM) with SmartPLS to determine the relationship among physicians' moral injuries, emotional exhaustion, and career abandonment intention. Results: The results indicated that occupational moral injury was positively related to emotional exhaustion and career abandonment intention. In addition, emotional exhaustion was found to play a mediating role in the relationship. Conclusion: To reduce physicians' intention to leave their career, physicians should be prepared for moral injury and psychological issues by offering psychological support and meeting their needs early at both the individual and organizational levels during and after the pandemic.

• Korean Journal of Exercise Nutrition
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• v.14 no.2
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• pp.81-86
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• 2010

The purpose of this study was to identify the factors associated with child's Body Mass Index (BMI) and physical activity. The participants (n = 133) were Korean juveniles (3^rd and 4^th graders) and their parents. They completed a questionnaire packet including the SPARK (Sports, Play, and Active Recreation for Kids) survey and the parent equivalent survey. Correlation, multiple linear regression and binary logistic regression analyses were applied to identify the association between child's BMI and 10 factors of SPARK as predict or variables. 25.6% of the participants were classified as overweight (21.1%) or obesity (4.5%). 3 parental factors including mother's BMI and frequency of mother's and father's physical activity were identified as significant predictors of children's BMI. The 10 variables accounted for 28% of the variance (p<.01) in the linear regression model. These results provide insight into parental factors which are related to a child's BMI and physical activity. Parental role modeling which refers to parents' efforts to model an active lifestyle for children plays an important role.

• Journal of Integrative Natural Science
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• v.16 no.3
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• pp.97-102
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• 2023

The gasdermins are a family of recently identified pore-forming effector proteins that cause membrane permeabilization and pyroptosis, a lytic pro-inflammatory type of cell death. A role in the regulation of cell proliferation and/or differentiation is suggested by the differentiation status-specific expression of gasdermin proteins in epithelial tissues. One of the GSDM protein is Gasdermin A (GSDMA), which decreased in stomach and esophageal cancers, suggesting a tumor suppressor role. GSDMA receptor antagonists have been researched as potential treatments for inflammatory diseases and baldness. GSDMA's significance in a wide range of disorders makes it an important therapeutic target. As a result, homology modelling of the GSDMA receptor was undertaken in the current study using the crystal structures of Mus musculus (GSDMA3), Human gasdermin D (GSDMD), and Murine gasdermin D (murine GSDMD). The best model was chosen based on the validation results after 20 models were developed utilising single template-based approaches. The generated structures can be used for further binding site and docking studies in the future.

• Asia pacific journal of information systems
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• v.30 no.3
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• pp.547-567
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• 2020

As the complexity of managing online personal information is increasing and data breach incidents frequently occur, online users feel a loss of control over their privacy. Such a situation leads to their cynical attitudes towards privacy protection, called privacy cynicism. This study aims to examine the role of privacy cynicism in online users' privacy behaviors. Data were gathered from a survey that 281 people participated in and were analyzed with covariance-based structural equation modeling. The findings of this study reveal that privacy cynicism has not only a direct influence on disclosure intention but also moderates an effect of privacy concerns on the intention. The analytical results also indicate that there is a nonlinear effect of privacy cynicism on the outcome variable. This study developed the concept of privacy cynicism—a phenomenon that significantly affects online privacy behavior but has been rarely examined. The study is an initial research into the nature and implications of privacy cynicism and furthermore clarified its role by the nonlinear relationship between privacy cynicism and the willingness to disclose personal information.

• Proceedings of the Korean Information Science Society Conference
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• 2004.10b
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• pp.406-408
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• 2004

To develop enterprise architecture based distributed application needs consideration of various factors such as division of role between web-designer and software developer, defining entity and its usage, database connection and transaction processing. This paper presents DONSL(Data Server of Non SQL-Query) architecture that provides solution to above aspects through web-tier object modeling guaranteeing efficient transaction processing and performance between web-tier and 08MS through simplified usage of query logic property.

• Proceedings of the Korean Information Science Society Conference
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• 2003.04c
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• pp.7-9
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• 2003

대부분의 객체지향 방법론은 객체를 중심으로 한 객체 모델링을 바탕으로 소프트웨어를 개발한다. 물론, 객체 모델링 방법은 여러 가지 장점을 가지고 있지만 복잡한 문제를 가진 대규모의 시스템에는 적합하지 않다. 따라서, 이런 복잡한 대규모 시스템을 객체의 패턴에 따라 간단한 모델로 분할할 필요성이 있으며 이를 위하여 역할 모델링 방법이 제안되었다. 본 논문은 객체의 패턴들을 추상화하고 복잡한 대규모 시스템을 관계의 분리를 통하여 간단한 모델로 생성할 수 있도록 객체 중심이 아닌 역할을 중심으로 한 역할 모델링 방법을 연구하였다.