• Environmental Analysis Health and Toxicology
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• 제30권sup호
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• pp.6.1-6.4
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• 2015

Objectives This study is conducted to estimate the cost paid by the public suffering from disease possibly caused by chemical and to examine the effect on public health. Methods Cost-benefit analysis is an important factor in analysis and decision-making and is an important policy decision tool in many countries. Cost-of-illness (COI), a kind of scale-based analysis method, estimates the potential value lost as a result of illness as a monetary unit and calculates the cost in terms of direct, indirect and psychological costs. This study estimates direct medical costs, transportation fees for hospitalization and outpatient treatment, and nursing fees through a number of patients suffering from disease caused by chemicals in order to analyze COI, taking into account the cost of productivity loss as an indirect cost. Results The total yearly cost of the diseases studied in 2012 is calculated as 77 million Korean won (KRW) per person. The direct and indirect costs being 52 million KRW and 23 million KRW, respectively. Within the total cost of illness, mental and behavioral disability costs amounted to 16 million KRW, relevant blood immunological parameters costs were 7.4 million KRW, and disease of the nervous system costs were 6.7 million KRW. Conclusions This study reports on a survey conducted by experts regarding diseases possibly caused by chemicals and estimates the cost for the general public. The results can be used to formulate a basic report for a social-economic evaluation of the permitted use of chemicals and limits of usage.

• 한국정보통신학회논문지
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• 제25권2호
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• pp.171-177
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• 2021

최근 머신러닝의 발전에 따라 일상생활과 산업에서 기술을 적용하는 사례들이 많아지고 있다. 금융 데이터와 머신러닝 기법을 활용한 연구 또한 활발하게 이루어지고 있다. 본 논문은 이러한 동향에 따라 상점 매출 데이터에 머신러닝 기법을 접목해 매출 예측 모델을 구축, 핀테크 산업에서의 활용 방안을 제시한다. 다양한 결측치 처리 기법을 적용하고 그래디언트 부스팅 기반의 머신러닝 기법인 XGBoost, LightGBM, CatBoost를 사용하여 각 모델의 상점 매출예측 성능을 비교한다. 연구 결과, 단일대체법 중 중앙값 대체법을 사용한 데이터셋에 XGBoost를 활용해 예측을 진행한 모델의 성능이 가장 우수했다. 연구를 통해 얻은 모델을 이용하여 상점의 매출 예측을 진행함으로서 핀테크 기업의 고객 상점들은 대출금을 상환하기 전 금융 보조를 받는 근거로, 핀테크 기업은 상환 가능성이 높은 우수 상점에 금융 상품을 제공하는 등 기업과 고객 모두에게 긍정적인 방향으로 활용할 수 있다.

• 한국식품위생안전성학회지
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• 제29권1호
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• pp.6-15
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• 2014

본 연구는 제외국의식중독균별저감화사례를조사, 비교하여 정보를 획득하고 식중독균 저감화 매뉴얼을 작성하며 저감화 정책방안을 제시하기 위한 기반 자료 확보를 목적으로 수행하였다. 선진 외국(미국, 덴마크, 일본)의 식중독 저감화 정책의 현황 및 사례조사에는 인터넷 자료, 관련 기관 전문가 인터뷰를 통하여 조사하였다. 미국의 신선농산물에서 미생물학적 위험요소 저감화(FDA), 미국 분쇄쇠고기에서 E. coli O157:H7의 저감화(USDA), 덴마크의 닭고기, 돼지고기, 계란에서 살모넬라 저감화, 일본의 어패류에서 장염비브리오 저감화 프로그램을 사례 연구로 제시하였으며 이들 국가의 저감 프로그램의 배경, 전략, 효과를 조사하고 장단점 분석을 실시하고 시사점을 도출하였다. 이들 제외국 정책 사례 연구와 국제기구 CODEX의 위해관리 체계를 결합하고 국내 현실을 반영하여 식중독 저감화 관리 매뉴얼로 저감 프로그램에 관한 일반 모델을 다음 순서로 제시하였다: 1) 위해관리 초기판단, 2) 식중독 저감화 프로그램 계획, 3) 대안 확인 및 선택, 4) 대안 실행(이해당사자별 역할 설정 및 대안 방법 적용), 5) 감시 활동, 6) 중간 재검토, 7) 목적 달성 때까지 대안 실행 지속적 실시 (만일 대안이 효과가 없으면 대안을 대체하거나 수정하여 식중독 저감화 목표 달성 시까지 실시), 8) 최종 평가에 보건에 미치는 영향을 확인하고 필요시 비용 편익 분석실시. 본 연구를 통해서 제시된 식중독 저감화 정책에 관한 시사점 및 식품안전의 이해당사자별 역할별로 도출된 식중독 저감화 정책 모델 및 매뉴얼은 미생물학적 위해관리를 수행하는데 향후 활용될 수 있다.

• 대한토목학회논문집
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• 제40권5호
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• pp.455-463
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• 2020

사용연수가 30년 이상 된 노후 시설물은 향후 10년 사이 3배 이상 급증될 것으로 조사되고 있다. 또한, 2017년 행정안전부 "내진설계기준 공통적용"개정으로 도로시설물의 내진성능 확보유무가 검토되어야 하며, 이는 기존 설계기준을 통해 내진보강 되었거나, 내진설계가 된 시설물을 포함한 모든 기존 도로시설물을 대상으로 내진성능 확보유무가 재평가 되어야 함을 의미한다. 이렇듯 대량의 시설물에 대한 내진성능관리를 위해서는 빠른 시간 내에 경제적이고 신뢰성 있는 결과를 제공할 수 있는 의사결정 지원기술이 필요하다. 하지만, 우리나라에서 사용되고 있는 지수평가방법은 결정론적인 방법으로서, 개별시설물의 내진성능을 정성적인 지수 값으로 산정하고 지수 값의 크기에 따라 내진보강 우선순위만을 결정하고 있어 합리적인 내진성능관리를 위한 다양한 의사결정을 지원하기 어려운 실정이다. 이러한 단점을 극복하고 내진성능관리 의사결정에 필요한 시설물의 직접손실비용, 사회·경제적 간접손실비용, 재원투입효과 등의 정보를 제공할 수 있는 지진위험도평가 방법으로 전환이 필요하다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제37권1호
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• pp.1-8
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• 2011

Introduction: The utility of the C-terminal cross-linking telopeptide test (CTX) as a method for staging Bisphosphonate-related osteonecrosis of the jaws (BRONJ) and its healing process was examined. Materials and Methods: A total 19 patients who were diagnosed with BRONJ underwent a fasted morning CTX test, were enrolled in this study. The serum CTX values ranged from 50 to 630 pg/mL (mean 60). The risk assessment was rated according to the CTX values of the individual patient (minimal risk, ${\geq}$ 150 pg/mL, moderate, 100 to 150 pg/mL, high, ${\leq}$100 pg/mL). The BRONJ scores were then calculated according to the number of BRONJ lesions and their stage. The operation was done as soon as possible, regardless of BORNJ stage. Results: The mean duration of bisphosphonate therapy was 4.1 years. Of the 19 patients, 15, 2 ans 2 received alendronate, risedronate and zoledronate, respecively. Of the 19 patients who underwent a sequestrectomy, saucerization and smoothing, 15 healed after the initial surgery, 1 patient healed after one more surgical procedure, 3 patients did not heal completely but showed improvement in symptoms. Therefore, 17 out of the 19 patients healed completely with complete mucosal coverage and the elimination of pain. The risk assessment using the CTX value and disease severity were not correlated (r=-0.264, P=0.275). In addition, the risk assessment using CTX value and healing after surgery were not correlated (r=-0.147, P=0.547). Conclusion: The serum CTX should be considered carefully by clinicians as part of overall management. Early surgical intervention is of benefit in the treatment of stage II BRONJ.

• 경영정보학연구
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• 제19권3호
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• pp.155-177
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• 2017

본 연구는 사용자가 개인정보를 경제적 관점으로 인지할 때, 개인적 특성, 거래 상대방의 특성, 상황적 특성에 따라 변화되는 개인정보가치를 비용편익분석 프레임워크를 바탕으로 살펴보았다. 이를 위하여 본 연구는 첫째, 개인이 인지하는 개인정보가치의 영향 요인 탐색, 둘째, 개인적, 거래 상대방, 상황적 특성에 따른 인터넷 사용자들의 개인정보가치 인식의 차이 확인, 셋째, 도출된 선행요인들을 바탕으로 개인의 지각된 위험에 미치는 영향력 검증, 넷째, 개인의 지각된 위험과 개인정보가치 사이의 상관관계를 분석하였다. 또한 개인적 특성인 위험회피 성향과 거래 상대방의 정보보안체계 확립 및 개인정보 유출 경험 여부, 상황에 대한 불확실성과 통제성의 요인에 따라 달라지는 개인의 지각된 위험을 파악하고 추가적으로 이에 따른 개인정보가치의 변화를 살펴보았다. 연구 분석 결과, 개인정보 유출 경험과 정보보안체계 확립 여부 및 상황의 통제성과 불확실성은 개인의 지각된 위험에 유의미한 영향을 미쳤으며, 지각된 위험의 증가는 개인정보가치 상승에 영향을 주는 것으로 나타났다. 따라서 본 연구의 결과는 개인의 지각된 위험과 그 특성 요인들, 그리고 개인정보가치의 관계를 바탕으로 개인정보가치 산정에 새로운 관점을 제시함과 동시에 향후, 개인정보가치 산정 모델의 토대를 제공하였다는 점에서 의의를 갖는다.

• 한국안전학회지
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• 제30권6호
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• pp.26-33
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• 2015

This study suggests systematic procedures to improve safety policies on prevention of industrial accidents associated with industrial machines and devices. Specifically, new method of cause analysis of industrial accidents associated with industrial machines and devices is suggested and the related accident data are re-analyzed. Effectiveness of direct safety regulations such as safety certification, self-declaration of conformity, safety device regulation and safety inspection of industrial machines and devices are also analyzed. Based on those analysis results, transition from the current user-oriented safety device regulation to more balanced direct regulations on both manufacturer and user is suggested. Together with severity and frequency of industrial accidents, unit severity and unit frequency need to be taken into account to further assess the risk associated with a particular industrial machine or device. Balance between safety regulations will be realized by proper adjustment of lists of safety certification and inspection, and certification and inspection standards. This will also guarantee the maximum benefit over cost in such safety regulations.

• Mycobiology
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• 제46권1호
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• pp.33-46
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• 2018

Gray mold (Botrytis cinerea) is one of the most common diseases of strawberries (Fragaria${\times}$ananassa Duchesne) worldwide. Although many chemical fungicides are used for controlling the growth of B. cinerea, the risk of the fungus developing chemical resistance together with consumer demand for reducing the use of chemical fungicides have necessitated an alternative method to control this pathogen. Various naturally occurring microbes aggressively attack plant pathogens and benefit plants by suppressing diseases; these microbes are referred to as biocontrol agents. However, screening of potent biocontrol agents is essential for their further development and commercialization. In this study, 24 strains of yeast with antagonistic ability against gray mold were isolated, and the antifungal activity of the volatile and diffusible metabolites was evaluated. Putative mechanisms of action associated with the biocontrol capacity of yeast strains against B. cinerea were studied through in vitro and in vivo assays. The volatile organic compounds produced by the Galactomyces candidum JYC1146 could be useful in the biological control of plant pathogens and therefore are potential alternative fungicides with low environmental impact.

• 한국건설관리학회논문집
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• 제5권2호
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• pp.144-152
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• 2004

Defining value as a measure of how well the project value objectives are met, Value Management Process (VMP) is considered to be any management effort or process that can proactively pursue one or more project objectives (i.e., security/safety, cost effectiveness, schedule optimization, and risk containment). The collection of 44 VMPs has been established based on a rigorous effort conducted by Construction Industry Institute (CII). Because varying circumstances on each project determine the level of suitability, it is crucial to identify which VMP should be implemented on a particular project. The current VMP selection process is primarily based on human intuition. The main objective of this paper is to provide a systematic method to facilitate the usage of VMPs on a particular project. This paper identified and quantified the selection principles (i.e., targeted value objectives, timing of initiation, project characteristics, and relative impact). The data collected from industry practitioners and VMP experts characterized each VMP in terms of the magnitude of benefit. An automated selection tool by Visual Basic Application (VBA) on MS Excel TM, was developed and proved its validity. As a pioneering study, this paper provides a comprehensive and structured knowledge on the subject of VMPs. From the industry's perspective, the automated selection tool, the premier of this study, contributes the facilitation of the VMP implementations in the construction industry thereby maximizing the potential benefits to a particular project.

• 대한관절경학회지
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• 제13권2호
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• pp.97-104
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• 2009

Optimal treatment of the torn anterior cruciate ligament (ACL) remains controversial. The complexity of surgically reproducing the natural biomechanical and anatomical function of the ACL has led to a diversity of reconstructive procedures. Controversy continues to exist regarding the best reconstructive procedure for the ACL deficient knee, but currently, there is no ideal method. Because of the increased frequency of ACL injury and the functional impairment resulting from that, the role of mechanoreceptors in the ACL recently has attracted considerable attention. Proper reconstruction of the ruptured ACL does not always have good results. Success after operation may depend not only on the mechanical stability but also on the quality of recovery of proprioception. It is well known that most ACL are ruptured in proximal half and most mechanoreceptors have been reported to be located in the subsynovial layer and near the tibial insertion of the ACL. Expected roles of tibial remnant is to enhance the revascularization and cellular proliferation of the graft, to preserve proprioceptive function, and to be able to acquire anatomical placement of the graft without roof impingement. The remnant of the ruptured ACL has been removed to clearly visualize the ACL footprint or decrease the risk of impingement and Cyclops lesion in most current techniques for ACL reconstruction. Therefore it seems reasonable to assume that preserving the tibial remnant as much as possible as a source of reinnervation, if technically possible without causing impingement, would be of potential benefit to the patient. In addition, it will facilitate the vascular ingrowth and ligamentization of the grafted ACL.