• Title/Summary/Keyword: Risk of Disease

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The Meta-Analysis Study on the Risk Factors of Stroke (메타분석을 통한 중풍 위험인자 연구)

  • Yeo, Hyeon-Su;Jun, Chan-Yong;Choi, You-Kyung;Ko, Seung-Gyu;Ko, Ho-Yeon;Park, Jong-Hyeong
    • Journal of Society of Preventive Korean Medicine
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    • v.12 no.3
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    • pp.59-65
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    • 2008
  • Objective : This study was conducted to integrate the results of studies which show the relationship between risk factors(smoking, drinking, intaking coffee, exercise, BMI, family history, hypertension, DM, hyperlipidemia, heart disease, TIA) and the incidence of stroke in Korean adults. Methods : We surveyed 17 stroke-related articles, published between 1995 and 2007, and conduct meta-analysis. And we estimated common odds ratio(OR). Results : The overall OR of risk factors associated CVD were as follow : Smoking had a 2.488 OR, no regular exercise had a 1.942 OR, $BMI{\geq}25$ had a 1.848 OR, hypertension had a 6.053 OR, DM had a 2.931 OR, heart disease had a 5.455 OR, and TIA had a 5.238 OR. Conclusion : The result of this study suggest that smoking, no regular exercise, $BMI{\geq}25$, hypertension, DM, heart disease, and TIA are important risk factor of stroke.

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Effectiveness of Intervntion for Cardiovascular Disease Prevention in Construction Workers (건설근로자 대상 심혈관질환 예방 중재의 효과)

  • Hwang, Sun-Kyung;Lee, Yoon-Ji;Kim, Bo-Kyung
    • Korean Journal of Occupational Health Nursing
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    • v.26 no.2
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    • pp.74-84
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    • 2017
  • Purpose: This study aimed to assess the risk of developing cardiovascular disease (CVD) and to evaluate the effects of intervention for CVD prevention in construction workers. Methods: A total of 497 workers participated the health status survey and finally 90 workers were analyzed for evaluation of the intervention with the one-group pretest-posttest design. The data were collected from the questionnaires and health examinations in the healthcare service for road constructor's CVD prevention as secondary analysis. The intervention of the healthcare was composed of CVD prevention education for all workers and face to face counselling for the high risk group of CVD risk during 6 months in workplace. Data were analyzed with descriptive statistics, $x^2$ test, Wilcoxon signed rank test, and paired t-test. Results: The moderate and high risk groups of CVD were 9.7% and 0.8%. After the intervention, the physical activity (MET-min/week) significantly increased (Z=-5.46, p<.001). But, there were no significant differences in blood pressure, fasting glucose, body mass index, and CVD risk appraisals between pre and post intervention. Conclusion: The findings imply that it is necessary to develop the health promotion program for construction workers which fully reflects the characteristics of individuals and the organization.

A Study of Subclinical Thyroid Function Disorder and the Risk of Coronary Heart Disease in Women (여성의 무증상 갑상샘 기능이상과 관상동맥질환 발생과의 관련성 연구)

  • Yeoum, Soon-Gyo;Park, Chai-Soon
    • Korean Journal of Adult Nursing
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    • v.22 no.1
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    • pp.80-89
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    • 2010
  • Purpose: This paper has attempted to investigate the association between the subclinical thyroid function disorder caused by natural change in thyroid hormones or thyroid remedies and the incidence of CHD. Methods: Data was analyzed of 7,675 women who had undergone health examinations in a hospital in Gyeonggi-do between January 2007 and December 2008. The covariation of the coronary risk factors such as age, BMI, HbA1C, systolic blood pressure, LDL:HDL-cholesterol ratio, CRP, smoking and exercise were analyzed by using logistic regression analysis. Results: A significant increase in serum TSH was observed with higher age (F=26.91, p=.00). In terms of age, the risk of CHD started to gradually increase since the 40s and sharply since the 60s (${\chi}^2$=113.29, p=.00). The serum TSH was the most significant parameter influencing CHD (B=.12, p=.00). The risk of coronary heart disease was 3.12 times higher in the subclinical hypothyroidism group (OR=3.12) while no significant difference was observed in the subclinical hyperthyroidism group. Conclusion: Subclinical hypothyroidism may be an independent risk factors for CHD. A nurse nursing patients with thyroid disorder should be well informed of their state of subclinical thyroid function disorder and make efforts to extend their health expectancy.

The Relationship between Pattern Identification and Stroke Risk Factors of Acute Ischemic stroke Patients (급성기 허혈성 뇌경색 환자들의 변증 분형과 위험 요인들간의 관련성 연구)

  • Lee, Ji-Hyun;Doo, Kyeong-Hee;Lu, Hsu-Yuan;Shim, So-Ra;Park, Joo-Young;Cho, Seung-Yeon;Jung, Woo-Sang;Moon, Sang-Kwan;Park, Jung-Mi;Ko, Chang-Nam;Cho, Ki-Ho;Kim, Young-Suk;Bae, Hyung-Sup;Park, Seong-uk
    • The Journal of the Society of Stroke on Korean Medicine
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    • v.13 no.1
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    • pp.43-51
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    • 2012
  • Object : The purpose of this study was to evaluate the relationship between pattern identification (PI) and stroke risk factors, such as hypertension, diabetes mellitus, dyslipidemia, stroke history, obesity, abdominal obesity and metabolic syndrome. Methods : 46 patients with acute ischemic stroke were recruited from May 2012 to November, 2012. We analyzed the data of 32 patients, and pattern identification was identified by resident and specialist of Korean medicine. We analized patient's PI and risk factor by Fisher's exact test. Results : We found that Dampness-phlegm group was more related with patient's metabolic syndrome than non Dampness-Phlegm group. And Yin deficiency group had less relationship with patient's metabolic syndrome, obesity, abdominal obesity and dyslipidemia than non Yin deficiency group. Conclusions : According to the analysis, these results provide evidence for relationship between the Dampness-phlegm group, Yin deficiency and metabolic syndrome.

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Gastrointestinal Stromal Tumors: A Clinicopathologic and Risk Stratification Study of 255 Cases from Pakistan and Review of Literature

  • Din, Nasir Ud;Ahmad, Zubair;Arshad, Huma;Idrees, Romana;Kayani, Naila
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.12
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    • pp.4873-4880
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    • 2015
  • Purpose: To describe the clinicopathological features of gastrointestinal stromal tumors (GIST) diagnosed in our section and to perform risk stratification of our cases by assigning them to specific risk categories and groups for disease progression based on proposals by Fletcher et al and Miettinen and Lasota. Materials and Results: We retrieved 255 cases of GIST diagnosed between 2003 and 2014. Over 59% were male. The age range was 16 to 83 years with a mean of 51 years. Over 70% occurred between 40 and 70 years of age. Average diameter of tumors was 10 cms. The stomach was the most common site accounting for about 40%. EGISTs constituted about 16%. On histologic examination, spindle cell morphology was seen in almost of 85% cases. CD117 was the most useful immunohistochemical antibody, positive in 98%. Risk stratification was possible for 220 cases. Based on Fletcher's consensus proposal, 62.3 gastric, 81.8% duodenal, 68% small intestinal, 72% colorectal and 89% EGISTs were assigned to the high risk category; while based on Miettinen and Lasota's algorithm, about 48% gastric, 100% duodenal, 76% small intestinal, 100% colorectal and 100% EGISTs in our study were associated with high risk for disease progression, tumor metastasis and tumor related death. Follow up was available in 95 patients; 26 were dead and 69 alive at follow up. Most of the patients who died had high risk disease and on average death occurred just a few months to a maximum of one to two years after initial surgical resection. Conclusions: Epidemiological and morphologic findings in our study were similar to international published data. The majority of cases in our study belonged to the high risk category.

Pathologic Risk Factors and Oncologic Outcomes in Early-stage Cervical Cancer Patients Treated by Radical Hysterectomy and Pelvic Lymphadenectomy at a Thai University Hospital: A 7 year Retrospective Review

  • Ruengkhachorn, Irene;Therasakvichya, Suwanit;Warnnissorn, Malee;Leelaphatanadit, Chairat;Sangkarat, Suthi;Srisombat, Jutatip
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5951-5956
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    • 2015
  • Background: To evaluate the rate of pathologic high-risk factors, intermediate-risk factors, and treatment outcomes in early-stage cervical cancer patients undergoing radical hysterectomy and pelvic lymphadenectomy (RHPL). Materials and Methods: Medical records of stage IA-IIA1 cervical cancer patients who underwent RHPL during the 2006 to 2012 time period and patient follow-up data until December 2013 were reviewed. Results: Of 331 patients, 52 women (15.7%) had pathologic high-risk factors and 59 women (17.8%) had intermediate-risk factors without high-risk factors. All studied patients had an initial complete response. At median follow-up time of 40.9 months (range 1-103.3 months) and mean follow-up time of$ 43.3{\pm}25.3$ months, 37 women had disease recurrence and 4 women had died of disease. The most common site of recurrence was the pelvis (64.8%). Five-year and 10-year disease free survival rates were 96.1% and 91.5%, respectively. Five-year and 10-year overall survival rates were 100% and 99.4%, respectively. Independent factors related to recurrence were pelvic node metastasis (odds ratio [OR], 2.670; 95%CI, 1.001-7.119), and >1/3 cervical stromal invasion (OR, 3.763; 95%CI, 1.483-9.549). Conclusions: The rates of pathologic high-risk and intermediate-risk factors should be considered and disclosed when counseling patients regarding primary treatment by RHPL. Oncologic outcomes of primary surgical treatment for early-stage cervical carcinoma were found to be excellent.

Heart Disease and Occupational Risk Factors in the Canadian Population: An Exploratory Study Using the Canadian Community Health Survey

  • Nowrouzi-Kia, Behdin;Li, Anson K.C.;Nguyen, Christine;Casole, Jennifer
    • Safety and Health at Work
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    • v.9 no.2
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    • pp.144-148
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    • 2018
  • Background: The objective of this study is to find temporal trends in the associations between cardiovascular disease and occupational risk factors in the context of the Canadian population. Methods: Population data were analyzed from the Canadian Community Health Survey (CCHS) collected between 2001 and 2014 for trends over time between heart disease and various occupational risk factors: hours worked, physical exertion at work, and occupation type (management/arts/education, business/finance, sales/services, trades/transportations, and primary industry/processing). Results: We found no significant difference in the average number of hours worked/wk between individuals who report having heart disease in all years of data except in 2011 ($F_{1,96}=7.02$, p = 0.009) and 2012 ($F_{1,96}=8.86$, p = 0.004). We also found a significant difference in the degree of physical exertion at work in 2001 ($F_{1,79}=7.45$, p = 0.008). There were statistically significant results of occupation type on self-reported heart disease from 2003 to 2014. Conclusion: Canadian data from the CCHS do not exhibit a trend toward an association between heart disease and the number of hours worked/wk. There is an association between heart disease and physical exertion at work, but the trend is inconsistent. The data indicate a trend toward an association between heart disease and occupation type, but further analysis is required to determine which occupation type may be associated with heart disease.

Study on the Risk Factors of Cerebrovascular Disease between Sasang Constitutions (사상체질에 따른 뇌혈관질환 위험인자의 분포에 대한 비교연구)

  • Kim, Do-Hyung;Yun, Seong-Woo;Ko, Chang-Nam;Kim, Seung-Eun
    • The Journal of Internal Korean Medicine
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    • v.22 no.3
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    • pp.379-382
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    • 2001
  • Objectives: Many studies have been reported about Sasang constitutional distribution of cerebrovascular disease(CVD) patients. But there has been little study about the risk factors of normal persons between Sasang constitutions. So we studied to evaluate the risk of CVD between Sasang constitutions. Methods: We retrospectively studied subjects without previous stroke($age{\geq}40$) who visited east-west medical examination center in Kang Nam Korean Hosipital, Kyung Hee University for last 2 years(1998.8.1.${\sim}$2000.7.31.). Sasang constitutional differentiation was performed by Questionnaire for the Constitution Classification(QSCC) II and subjects who couldn't be classifiea by QSCC II were excluded. Results : Total 363 subjects participated in this study(Taeyangin 0, Taeumin 103, Soyangin 113, Soumin 92, obscure 55). Diabetes mellitus(p<0.05), hyperlipidemia(p<0.01), obesity(p=0.000) were significantly prevalent in Taeumin. Hypertension and heart disease had no significant difference between Sasang constitutions. Conclusions: This study showed that the risk factors of CVD were more prevalent in Taeumin. Therefore we guess that Taeumin has high risk of CVD.

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Design of Rough Set Theory Based Disease Monitoring System for Healthcare (헬스 케어를 위한 RDMS 설계)

  • Lee, Byung-Kwan;Jeong, Eun-Hee
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38C no.12
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    • pp.1095-1105
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    • 2013
  • This paper proposes the RDMS(Rough Set Theory based Disease Monitoring System) which efficiently manages diseases in Healthcare System. The RDMS is made up of DCM(Data Collection Module), RDRGM(RST based Disease Rules Generation Module), and HMM(Healthcare Monitoring Module). The DCM collects bio-metric informations from bio sensor of patient and stores it in RDMS DB according to the processing procedure of data. The RDRGM generates disease rules using the core of RST and the support of attributes. The HMM predicts a patient's disease by analyzing not only the risk quotient but also that of complications on the patient's disease by using the collected patient's information by DCM and transfers a visualized patient's information to a patient, a family doctor, etc according to a patient's risk quotient. Also the HMM predicts the patient's disease by comparing and analyzing a patient's medical information, a current patient's health condition, and a patient's family history according to the rules generated by RDRGM and can provide the Patient-Customized Medical Service and the medical information with the prediction result rapidly and reliably.

The Usefulness of Obesity Indices for the Coronary Risk Factors in an Urban Inhabitants (도시지역 주민의 관상동맥질환 위험인자에 관련한 비만지표의 유용성 검토)

  • Park, Sung-Kyeong;Kim, Kwang-Hwan;Cho, Young-Chae
    • Journal of Preventive Medicine and Public Health
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    • v.39 no.6
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    • pp.447-454
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    • 2006
  • Objectives : To determine obesity for the screening of individuals at high risk of coronary heart disease in urban areas. Methods : Data were obtained from 4,137 adults between 19 and 85 years of age (2,372 males, 1,765 females), not recognized as taking medicines for cardiovascular diseases, who underwent a health check-up at the health promotion center of university hospitals in cities between Jan. 2003 and Dec. 2004. The variables studied were divided into two broad categories, and their relationships examined. obesity indices and risk factors for coronary heart disease. To reveal the relation between each of the obesity indices and the proportion of individuals at risk of coronary heart disease, the obesity indices were stratified and odds ratios obtained after age adjustment. Results : From a gender comparison of anthropometric measures, men were found to have significantly greater heights, weights, and waist and hip circumferences than women. From a gender comparison by the obesity indices, women were found to have significantly higher BMI, %Fat, waist to hip and waist to stature ratios than men. As obesity indices, the waist to stature ratio and the waist circumference were strongly correlated with coronary risk factors, both in men and women. The age-adjusted odds ratio of coronary risk factors increased significantly with increasing waist circumference, BMI, %fat, waist to hip and waist to stature ratios, and were highest specifically for the waist to stature ratio and the waist circumference. Conclusions : The study results showed that the waist to stature ratio and the waist circumference, as obesity indices, were most closely correlated with coronary risk factors. It is suggested that the waist to stature ratio and, specifically, the waist circumference can be effectively used in the field of health management for screening those with high levels of coronary risk factors.