• YAKHAK HOEJI
• /
• v.58 no.4
• /
• pp.229-244
• /
• 2014

Background: Antibiotic skin test(AST) is very useful for the diagnosis of drug allergies to prevent immediate allergic reactions. Although it is a safe and widespread method, it is performed very diversely by doctors and nurses without consistency and it also differs from countries and hospitals. This study aims to evaluate the current practice of AST by nurses in Korea and to compare it to the general guidelines. Methods: During January 1, 2013 to May 20, 2013, the study was conducted as questionnaires and case-based survey. The questionnaires were given to the nurses who were randomly selected in various University Hospitals (University Hospitals N=276, and Medical center N=19). The case-based surveys were given to the nurses who were conducting AST at various wards of a University Hospital (N=130). The analysis and evaluations of the responses were carried out. Results: The response rate for the questionnaires was 97.6% and 130 cases of the actual case-based surveys were collected. There were clear differences between the survey results and the general guidelines, such as the method of skin test (skin prick test was not conducted), the method of patient selection for AST, test drugs, concentration, volume and interpretation of AST. AST conducted by nurses was highly variable and inconsistent, even among nurses who worked in the same wards and hospitals. Manufactured standard concentration antibiotic solution of AST showed consistency of concentration to a certain degree. Conclusion: Although the general guidelines have been published by several countries including Korea, these are not a great help to nurses as they lack details for conducting AST, practical consideration for nurses in the clinical setting, propagation and education. Standardized guideline for nurses should be published and it should be a safe, clear, comfortable and easily accessible protocol. Futhermore, additional antibiotic solutions to standardize skin test should be developed and manufactured. Lastly, it would be the pharmacists role to compare their hospitals antibiotic skin test methods with the standard guidelines and develop a protocol within the hospital for patients' safety, and to strive to consistently implement it.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
• /
• v.9 no.4
• /
• pp.13-25
• /
• 2014

This study advances research on new venture by taking the organizational ecology perspective to explore the relationship between social legitimacy and new venture performance. We examine how entrepreneurs' organizing activity and social norm shape the social legitimacy. This paper also categorizes the social norms into three parts: social norm that is 1) supporting success achieved through one's own effort 2) encouraging start-up, and 3) promoting risk-taking. Using a dataset of PSED(Panel Study of Entrepreneurial Dynamics) from 2005 to 2011, we found that entrepreneurs' organizing activity has a positive effect on new venture performance. In addition, this study presents the moderating effects of 'liability of newness' that decreases the effect of organizing activity on new venture performance. Interestingly, with respect to the social norm, 'liability of newness' only moderates the relationship between start-up encouraging social norm and new venture performance.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
• /
• v.9 no.4
• /
• pp.65-76
• /
• 2014

The basic purpose of this study is to examine the relationship among entrepreneurial intention, university supports for startup, and startup activities of university students. For the study, we identified the influence factors of students' startup intention based on reviewing preceding studies and examined how these factors affect their intention of new venture startup. In addition, this study attempted to examine how these factors that can have a significant impact on entrepreneurial intention affect startup activities and analyzed how entrepreneurial intention would mediate the relationship between these influence factors and startup activities. A total of 769 students who chosen by random were surveyed and all questionnaires were sent by mail to the universities that entrepreneurship education and entrepreneurial programs were selected as the forerunners from the government. As a result, this study revealed that student's psychological traits such as entrepreneurial self-efficacy and risk-taking have significant effect on the intention of startup. And student's exposure to the role models and various entrepreneurial experiences such as entrepreneurship education and entrepreneurial student's club in the university has significantly positive influence on the intention of startup. This study also found that the effects of these explanatory variables of this research on startup activities have been partially mediated by entrepreneurial intention. The entrepreneurial intention was also proven to have a significant effect on startup activities. Finally, the extent to which university supports activities for students' startup moderated the relationship between entrepreneurial intention and university students' startup activities. We believe that these results of this study contribute to the understanding of the entrepreneurship process both theoretical and practical perspectives.

• Journal of Chest Surgery
• /
• v.47 no.4
• /
• pp.367-372
• /
• 2014

Background: We compared the mid-term results of the Cox maze IV procedure using argon-based cryoablation with a procedure using $N_2O$-based cryoablation. Methods: From May 2006 to June 2012, 138 patients (mean age, $58.2{\pm}11.0$ years) underwent the Cox maze IV procedure. Eighty-five patients underwent the maze procedure using an $N_2O$-based cryoprobe (group N), and 53 patients underwent the maze procedure using an argon-based cryoprobe (group A). Bipolar radiofrequency ablation was concomitantly used in 131 patients. The presence of atrial fibrillation immediately, 6 months, 1 year, and 2 years after surgery was compared. Results: Early mortality occurred in 6 patients (4.3%). There were no differences in early mortality or postoperative complications between the two groups. Nineteen of 115 patients (16.5%) remained in atrial fibrillation at postoperative 12 months (14 of 80 patients (17.5%) in group N and 5 of 35 patients (14.3%) in group A, p=0.669). There were no differences in the number of patients who remained in atrial fibrillation at any of the time periods except in the immediate postoperative period. A multivariable analysis revealed that the energy source of cryoablation was not associated with the presence of atrial fibrillation at 1 year (p=0.862) and that a fine F wave (<0.1 mV) was the only risk factor predicting the presence of atrial fibrillation at 1 year (p<0.001, odds ratio=20.287). Conclusion: The Cox maze IV procedure using an argon-based cryoprobe was safe and effective compared with the maze procedure using an $N_2O$-based cryoprobe in terms of operative outcomes and the restoration of sinus rhythm for up to 2 years after surgery.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.15 no.7
• /
• pp.4404-4415
• /
• 2014

This study was carried out to verify the relationship between the job satisfaction and turnover intention of nurses working in general hospitals The study included 312 nurses working in three general hospitals located in Gyeoungpook area. The data was collected by a survey using self-administered questionnaires structured from February 25 to March 16, 2013. The level of turnover intention was negatively correlated with job satisfaction and professional position, autonomy, administrative capacity, pay, task requirement. In logistic regression analysis, the adjusted odds ratio of the high risk turnover intention was increased significantly in the lower groups of job satisfaction, job autonomy, administrative capacity and pay than in the higher groups of these items. Hierarchical multiple regression analysis showed that the turnover intention correlated significantly with the education level, subjective sleep evaluation, job career, job position, monthly pay, satisfaction with work, fitness of the job, career choice motives, physical burden of work, and job satisfaction. In addition, there was a negative correlation between the job satisfaction and turnover intention in the studied nurses, which showed that the turnover intention increased with decreasing level of job satisfaction. The variations in the job related characteristics and job satisfaction have a significant influence on the turnover intention.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.9
• /
• pp.3997-4003
• /
• 2014

Background: Infection with certain human papillomavirus (HPV) genotypes is the most important risk factor related with cervical cancer. The objective of the present study was to investigate the prevalence of HPV infection, the distribution of HPV genotypes and HPV E6/E7 oncogene mRNA expression in Turkish women with different cervical cytological findings in Mersin province, Southern Turkey. Materials and Methods: A total of 476 cytological samples belonging to women with normal and abnormal cervical Pap smears were enrolled in the study. For the detection and genotyping assay, a PCR/direct cycle sequencing approach was used. E6/E7 mRNA expression of HPV-16, 18, 31, 33, and 45 was determined by type-specific real-time NASBA assay (NucliSENS EasyQ$^{(R)}$HPV v1.1). Results: Of the 476 samples, 106 (22.3%) were found to be positive for HPV DNA by PCR. The presence of HPV was significantly more common (p<0.001) in HSIL (6/8, 75%) when compared with LSIL (6/14, 42.9%), ASC-US (22/74, 29.7%) and normal cytology (72/380, 18.9%). The most prevalent genotypes were, in descending order of frequency, HPV genotype 66 (22.6%), 16 (20.8%), 6 (14.2%), 31 (11.3%), 53 (5.7%), and 83 (4.7%). HPV E6/E7 oncogene mRNA positivity (12/476, 2.5%) was lower than DNA positivity (38/476, 7.9%). Conclusions: Our data present a wide distribution of HPV genotypes in the analyzed population. HPV genotypes 66, 16, 6, 31, 53 and 83 were the predominant types and most of them were potential carcinogenic types. Because of the differences between HPV E6/E7 mRNA and DNA positivity, further studies are required to test the role of mRNA testing in the triage of women with abnormal cervical cytology or follow up of HPV DNA positive and cytology negative. These epidemiological data will be important to determine the future impact of vaccination on HPV infected women in our region.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.9
• /
• pp.4085-4089
• /
• 2014

Background: Atelectasis is an important prognostic factor that can cause pleuritic chest pain, coughing or dyspnea, and even may be a cause of death. In this study, we aimed to investigate the potential impact of atelectasis and PET parameters on survival and the relation between atelectasis and PET parameters. Materials and Methods: The study consisted of patients with lung cancer with or without atelectasis who underwent $^{18}F$-FDG PET/CT examination before receiving any treatment. $^{18}F$-FDG PET/CT derived parameters including tumor size, SUVmax, SUVmean, MTV, total lesion glycosis (TLG), SUV mean of atelectasis area, atelectasis volume, and histological and TNM stage were considered as potential prognostic factors for overall survival. Results: Fifty consecutive lung cancer patients (22 patients with atelectasis and 28 patients without atelectasis, median age of 65 years) were evaluated in the present study. There was no relationship between tumor size and presence or absence of atelectasis, nor between presence/absence of atelectasis and TLG of primary tumors. The overall one-year survival rate was 83% and median survival was 20 months (n=22) in the presence of atelectasis; the overall one-year survival rate was 65.7% (n=28) and median survival was 16 months (p=0.138) in the absence of atelectasis. With respect to PFS; the one-year survival rate of AT+ patients was 81.8% and median survival was 19 months; the one-year survival rate of AT-patients was 64.3% and median survival was 16 months (p=0.159). According to univariate analysis, MTV, TLG and tumor size were significant risk factors for PFS and OS (p<0.05). However, SUVmax was not a significant factor for PFS and OS (p>0.05). Conclusions: The present study suggested that total lesion glycolysis and metabolic tumor volume were important predictors of survival in lung cancer patients, in contrast to SUVmax. In addition, having a segmental lung atelectasis seems not to be a significant factor on survival.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.59 no.1
• /
• pp.54-58
• /
• 2014

Climate change may result in greater risk of yield reduction of waxy corn due to drought stress and maize is one of the sensitive crops to the soil moisture shortage. While irrigation is the most effective practice to reduce the drought damage, farmers are unable to apply water due to limited water resource and irrigating facilities. The study was conducted to investigate the application effect of salicylic acid and abscisic acid on reducing drought stress of waxy corn (Zea mays L.). Drought stress was imposed by withholding irrigation from 9 days before anthesis to 14 days after anthesis. Salicylic acid or abscisic acid was applied on tasseling date at concentration of 0.5 mM and 0.1 mM, respectively. Drought stress increased anthesis-silking interval (ASI) by 3.0~3.3 days and decreased plant height, ear length, ear diameter, number of rows in ear, and yield by 47~51 cm, 4.6~5.0 cm, 4.4~5.3 mm, 1.5~2.0, and 2.4~2.5 Mg/ha, respectively. Application of salicylic acid and abscisic acid did not significantly reduced the drought injuries of waxy corn. Pretreatment of the plant growth regulators before water deficit stress or divided application at low concentration may be required to obtain the reduction effect on drought stress of waxy corn.

• Korean Journal of Construction Engineering and Management
• /
• v.15 no.5
• /
• pp.138-146
• /
• 2014

Modular construction is one of the arising issues in the Korean construction industry due to shorter construction period and higher productivity on site. It is also expected that modular construction market would expand rapidly because of increasing demand of small houses by nuclear families and eco-friendly construction. However modular construction cases have been limited in Korea because of little demand in the market and the construction prices are even higher that the regular reinforced concrete methods. Even worse, because there is no standard bill of services exists in the industry, it may lead to the risk of construction expenses. So, the purpose of this study is focused on the development of bill of services which reflects characteristics and process of modular construction. In order to do this, the concepts and process of modular construction, WBS and CBS are analyzed. Analyses of the case studies and experts interview were executed so that proper principles for organizing bill of service of modular construction is established. Finally according to the 3 steps of modular construction, factory manufacturing, on-site modular construction and on-site general construction, the standard bill of services were suggested with the related coding system.

• Korean Journal of Construction Engineering and Management
• /
• v.15 no.5
• /
• pp.94-102
• /
• 2014

This study analyzes necessity of expanding construction insurance and estimates required budget. Construction insurance is obliged by National Contract Law and Local Contract Law to protect projet owners and contractors from any unexpected construction risk such as financial losses in construction process. Currently the contracts of design-build and alternate-bid projects as well as PQ project, which are greater than 20 billion won, require the contractors to provide construction insurances in Korea. Insurance premiums are borne by the public project owner. Those contractors whose contract volume is less than 20 billion won burden all risks of projects at their cost. This causes equity problem. Because small-and-medium contractors are discriminated against large contractors since insurance-obliged projects are performed by large contractors and insurance premiums are borne by the public project owner. On the other hands, in all engineering projects, regardless of volume, insurance premiums are borne by the project owner. Therefore current regulation has to be improved, by expanding to all public projects. The average ratio of unobliged projects is 46%, in recent 3 years, prime cost of insurance companies is estimated 0.2%. Moreover considering risks of each construction type, prime cost of unobliged works is estimated as 0.13%. Hence additional necessary budget is estimated to be 2.09 billion won if total volume of public work is 3.5 trillion won. And 2.39 billion won is derived if total volume of public projects is 4 trillion won.