• BMB Reports
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• v.29 no.5
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• pp.429-435
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• 1996

To investigate the structure-antagonistic relationship of the cyclohexapeptide L-659,877, a selective NK-2 tachykinin receptor antagonist, seven analogues were chemically synthesized by a solid phase method. The agonistic and antagonistic activities of the analogues were evaluated by contraction assay using the smooth muscle of guinea pig trachea (GPT) containing the NK-2 receptor. It was shown that the aromatic ring of Phe at position 3 and the sulfur group of Met at position 6 in L-659,877 were essential for binding to the NK-2 receptor. Decrease in antagonistic activity of L-659,877 caused by substituting Leu for Nle at position 5 indicates that the ${\gamma}$ methyl group and side chain length of Leu plays an important role in its antagonistic action. Although the activity was slightly lower than L-659,877, cyclo $[{\beta}Ala^{8}]NKA(4-10)$ (analogue 1) showed potential antagonistic activity for the NK-2 receptor. It was confirmed that the expansion of the ring in L-659,877 by substitution of ${\beta}Ala$ for Gly at position 4 stabilized its conformation monitored by CD spectra. The results suggest that analogue 1 can be used as a new leader compound to design a more powerful, selective, and stable NK-2 receptor antagonist.

• Journal of the Korean Geotechnical Society
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• v.24 no.7
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• pp.75-80
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• 2008

When a saturated clay is sampled in an undisturbed manner from a bore hole, the sample extends vertically and shrinks horizontally under undrained conditions due to stress release. The conventional consolidation test specimen is trimmed from the expanded sample so that its diameter is equal to the inner diameter of the consolidation test ring, and this test procedure does not reproduce the actual consolidation behavior. The measurement of sample extension was conducted by means of overcoring method showed that the extension strains were 1 to 2%. To simulate the in-situ consolidation behavior, we proposed the consolidation test method that uses a specimen with a slightly smaller diameter than the inside diameter of consolidometer so that the specimen expands laterally to the inside of the ring.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.89.2-89.2
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• 2013

Solar energetic transients, e.g., flares, CMEs, etc., release large amount of energy which is expected to excite acoustic waves (p-modes) by exerting mechanical impulse of the thermal expansion of the flare on the photosphere. We study the p-mode properties of flaring and dormant active regions (ARs) to find association between flare and p-mode parameters. We compute the magnetic and flare activity indices of ARs using the line-of-sight magnetograms and GOES X-ray fluxes, respectively. The p-mode parameters are computed from the ring-diagram analysis. We correct p-mode parameters for magnetic field, filling factors and foreshortening by multiple linear-regression analysis. Our analysis of several flaring and dormant ARs observed during the Carrington rotations 1980-2109, showed strong association of mode parameters with magnetic and flare activities. We find that the mode parameters are contaminated by the geometrical effect. Mode amplitude decreases with angular distance from the solar disc centre. The mode width increases with magnetic activity while amplitude showed opposite relation due to mode absorption by the sunspot. After correcting modes due to all geometrical effects, magnetic activity and filling factor, we find that the modes amplitude, and mode energy increases with flare energy while width shows opposite relation.

• International Journal of Aeronautical and Space Sciences
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• v.17 no.1
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• pp.120-131
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• 2016

The full results of troubleshooting process related to the flight control system of a tilt-rotor type UAV in the flight tests are described. Flight tests were conducted in helicopter, conversion, and airplane modes. The vehicle was flown using automatic functions, which include speed-hold, altitude-hold, heading-hold, guidance modes, as well as automatic take-off and landing. Many unexpected problems occurred during the envelope expansion tests which were mostly under those automatic functions. The anomalies in helicopter mode include vortex ring state (VRS), long delay in the automatic take-off, and the initial overshoot in the automatic landing. In contrast, the anomalies in conversion mode are untrimmed AOS oscillation and the calibration errors of the air data sensors. The problems of low damping in rotor speed and roll rate responses are found in airplane mode. Once all of the known problems had been solved, the vehicle in airplane mode gradually reached the maximum design speed of 440km/h at the operation altitude of 3km. This paper also presents a comprehensive detailing of the control systems of the tilt-rotor unmanned air vehicle (UAV).

• Journal of the Korean Mathematical Society
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• v.55 no.1
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• pp.101-129
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• 2018

From an analytical perspective, we introduce a sequence of Cartier operators that act on the field of formal Laurent series in one variable with coefficients in a field of positive characteristic p. In this work, we discover the binomial inversion formula between Hasse derivatives and Cartier operators, implying that Cartier operators can play a prominent role in various objects of study in function field arithmetic, as a suitable substitute for higher derivatives. For an applicable object, the Wronskian criteria associated with Cartier operators are introduced. These results stem from a careful study of two types of Cartier operators on the power series ring ${\mathbf{F}}_q$[[T]] in one variable T over a finite field ${\mathbf{F}}_q$ of q elements. Accordingly, we show that two sequences of Cartier operators are an orthonormal basis of the space of continuous ${\mathbf{F}}_q$-linear functions on ${\mathbf{F}}_q$[[T]]. According to the digit principle, every continuous function on ${\mathbf{F}}_q$[[T]] is uniquely written in terms of a q-adic extension of Cartier operators, with a closed-form of expansion coefficients for each of the two cases. Moreover, the p-adic analogues of Cartier operators are discussed as orthonormal bases for the space of continuous functions on ${\mathbf{Z}}_p$.

• Journal of Powder Materials
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• v.3 no.4
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• pp.227-232
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• 1996

(i) The development of a metallurgical bond during the spray forming of clad products has offered the possibility of manufacturing large rolls, including those used in hot and cold strip mills. Small rolls are already being produced in Japan. (ii) Technical developments, including the use-of-multi-atomizers have resulted in the elimination of porosity from the internal bore of a sprayed tube. Bimetallic tubing can also be manufactured and the installation of a 4.5 ton tube plant in the USA should provide low operation costs. (iii) Spray forming offers a potentially low cost manufacturing route for superalloy ring/casing components in high strength superalloys. (iv) A large pilot plant has been built for the spray forming of ultra-clean superalloys for turbine disc applications. (v) Using twin-atomizing technology, special steel billets have been spray formed up to 400mm diameter with deposition yields in excess of 90%. (vi) Al/Si alloy extrusion billets with excellent dimensional tolerances are being manufactured for large scale automotive applications. Several new aluminum alloys have also been developed, including high strength, low density and low cocfficient of expansion materials. (vii) New copper alloys have been developed and pilot plants are in operation to produce these alloys once markets have become established.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2011.11a
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• pp.477-480
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• 2011

The stress analyses of the 'U'-shaped multi-ply reinforced gimbal bellows under high pressure and rotational displacement loadings are performed at the room and cryogenic temperatures. The bellows are used for the Lox pipe line which connects the combustion chamber with the turbopump of a liquid rocket engine. The distributions of the stress, the strains and the contact pressures are obtained from the finite element analysis considering the geometric non-linearities of the contacts between the plies and the material one of the isotropic plasticity. Those are compared with the stress results from EJMA (Expansion Joint Manufacturing Association) standard. Also, the effects of the operating temperature and the reinforcing ring on the stresses are investigated.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2008.04a
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• pp.132-139
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• 2008

The blade vibration problem of bladed disk is the most critical subject to consider since it directly affects the stable performance of the engine as well as life of the engine. Especially, due to complicated vibration pattern of the bladed disk, more effort was required for vibration analysis and test. The research of measuring the vibration of the bladed disk, using NSMS(Non-intrusive stress measurement) instead of Aeromechanics testing method requiring slip ring or telemetry system with strain gauge, was successful. These testing can report the actual stresses seen on the blades; detect synchronous resonances that are the source of high cycle fatigue (HCF) in blades; measure individual blade mis-tuning and coupled resonances in bladed disks. In order to minimize the error being created due to heat expansion, the tip timing sensor is installed parallel to the blade trailing edge, yielding optimal result. Also, when working on finite element analysis, the whole bladed disk has gone through three-dimensional analysis, evaluating the family mode. The result of the analysis matched well with the test result.

• Carbon letters
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• v.5 no.4
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• pp.159-163
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• 2004

The polymer-ceramic hybrid, known as 'ceramer', was synthesized by a sol-gel process by incorporating different amount of alkoxide as source of silicon in resorcinol-formaldehyde in presence of basic catalyst to get different percentage of silicon in ultimate carbonized composites. FTIR of the ceramer confirms that it is a network of Si-O-Si, Si-O-$CH_2$ and Si-OH type groups linked with benzene ring. Different amount of silicon in the ceramer exhibits varying temperature of thermal stability and lower coefficient of thermal expansion as compared to pure resorcinol-formaldehyde resin. The lower value of CTE in ceramer is due to existence of silica and resorcinol -formaldehyde in co-continuous phase. Unidirectional composites prepared with ceramer matrix and high-strength carbon fibers show lower value of flexural strength at polymer stage as compared to those prepared with resorcinol-formaldehyde resin. However, after heat treatment to $1450^{\circ}C$, the ceramer matrix composites show large improvement in the mechanical properties, i.e. with 7% silicon in the ceramer, the flexural strength is enhanced by 100% and flexural modulus value by 40% as compared to that of pure resorcinol-formaldehyde resin matrix composites.

• Journal of the Korean Institute of Gas
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• v.9 no.1 s.26
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• pp.26-32
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• 2005

This paper presents the design safety of metal seals in pressure vessels. For a high-pressure vessel, a metal seal is usually used as a primary sealing, and an elastomeric rubber O-ring is adopted as a secondary sealing unit. The FEM computed results show that an aluminium material for sealing a gas leakage is superior to a steel one because of the thermal expansion rate. The deformation and stress distributions on the metal seal and pressure vessel structures are mainly dominated by transferred temperature compared to those of the gas pressure in which is supplied by an external pump. Thus, the temperature of a metal seal material should be restricted to under $200^{\circ}C$.