• Title/Summary/Keyword: Richard Hong

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Temporal and Spatial Expression Patterns of Nine Arabidopsis Genes Encoding Jumonji C-Domain Proteins

  • Hong, Eun-Hye;Jeong, Young-Min;Ryu, Jee-Youn;Amasino, Richard M.;Noh, Bosl;Noh, Yoo-Sun
    • Molecules and Cells
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    • v.27 no.4
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    • pp.481-490
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    • 2009
  • Diverse posttranslational modifications of histones, such as acetylation and methylation, play important roles in controlling gene expression. Histone methylation in particular is involved in a broad range of biological processes, including heterochromatin formation, X-chromosome inactivation, genomic imprinting, and transcriptional regulation. Recently, it has been demonstrated that proteins containing the Jumonji (Jmj) C domain can demethylate histones. In Arabidopsis, twenty-one genes encode JmjC domain-containing proteins, which can be clustered into five clades. To address the biological roles of the Arabidopsis genes encoding JmjC-domain proteins, we analyzed the temporal and spatial expression patterns of nine genes. RT-PCR analyses indicate all nine Arabidopsis thaliana Jmj (AtJmj) genes studied are actively expressed in various tissues. Furthermore, studies of transgenic plants harboring AtJmj::${\beta}$-glucuronidase fusion constructs reveal that these nine AtJmj genes are expressed in a developmentally and spatially regulated manner.

Competition Responses of Populus alba Clone ‘Bolleana’ to red:far-red light

  • Bae, Han-hong;Kang, Ho-duck;Richard B. Hall
    • Plant Resources
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    • v.7 no.1
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    • pp.77-86
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    • 2004
  • The reduced ratio of red:far-red (R:FR) light acts as a measure of the proximity of competitors and plants can detect the potentially competing neighbor plants by perceiving reflected R:FR signals and initiate the response of “shade avoidance” before actual shading occurs. The phytochrome system is responsible for monitoring the changes in the R:FR and initiating the shade avoidance response. The response to low R:FR ratio was studied in a white aspen Populus alba clone ‘Bolleana’ using two filter systems: a clear plastic filter system that allows a R:FR ratio less than 1.0 to pass from adjacent border plant reflection; and a special commercial plastic that blocks FR light and creates a R:FR ratio above 3.0. The reduced R:FR signals enhanced the stem elongation in response to competition at the expense of relative stem diameter growth. Trees grown inside clear chambers were 27 % taller than trees grown inside the FR-blocking filter chambers. Stem taper of clear chamber trees was 16% less than the FR-blocking filter trees. Low R:FR also induced 22% more stem dry weight and 13% greater petiole length per leaf compared to the FR-blocking filter trees. There were no statistically significant differences in leaf area, leaf number increment, and total dry weight between the two light filter treatments.

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Blind Drift Calibration using Deep Learning Approach to Conventional Sensors on Structural Model

  • Kutchi, Jacob;Robbins, Kendall;De Leon, David;Seek, Michael;Jung, Younghan;Qian, Lei;Mu, Richard;Hong, Liang;Li, Yaohang
    • International conference on construction engineering and project management
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    • 2022.06a
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    • pp.814-822
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    • 2022
  • The deployment of sensors for Structural Health Monitoring requires a complicated network arrangement, ground truthing, and calibration for validating sensor performance periodically. Any conventional sensor on a structural element is also subjected to static and dynamic vertical loadings in conjunction with other environmental factors, such as brightness, noise, temperature, and humidity. A structural model with strain gauges was built and tested to get realistic sensory information. This paper investigates different deep learning architectures and algorithms, including unsupervised, autoencoder, and supervised methods, to benchmark blind drift calibration methods using deep learning. It involves a fully connected neural network (FCNN), a long short-term memory (LSTM), and a gated recurrent unit (GRU) to address the blind drift calibration problem (i.e., performing calibrations of installed sensors when ground truth is not available). The results show that the supervised methods perform much better than unsupervised methods, such as an autoencoder, when ground truths are available. Furthermore, taking advantage of time-series information, the GRU model generates the most precise predictions to remove the drift overall.

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A Study on Characteristics of Neo-Avant-Garde in Furniture Design -Focusing on the Thought before and after the 1960s- (가구디자인에 있어서의 네오-아방가르드적 특성 연구 -1960년대 전후 사조를 중심으로-)

  • Choi, Lee-Seoung;Kim, Hyung-Woo
    • Journal of the Korea Furniture Society
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    • v.19 no.3
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    • pp.180-192
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    • 2008
  • The historian called Peter Burger divided it into historical avant-garde before and after the first World War (Dadaism, Futurist, Geometric Abstract, etc.) and Neo- avant-garde during the period of forming social foundation that would be ready to accept new forms of art in the USA, the center of capitalism, after the 2nd World War such as pop art and conceptual art including the then emerging avant-garde minimal art. Meanwhile, he interpreted that Neo- avant-garde succeeded the spirit of historical avant-garde. For modem furniture, the avant-garde terminologies are discussed from the aspect of epistemology or symbolism. On the other hand, they would be exclusively used for advertising slogans, however, it is considered as difficult due to vague terms or their characteristics. This study relates the points of historians such as Peter Burger for theoretical proposal and Richard Kostelanetz's point for formal issues, and contracts and arranges the avant-garde terminologies and its characteristics to the meaning of "getting out of the present decadent trend - aiming for future", "transcending the present aesthetic custom - renovation" and "violating the rules already established in the process of entering new areas - freshness of unfairness". The study was meaningful in providing fundamental clues based on the historical discussion and artists for Neo- avant-garde in the 1960s, that is, the mainstream of design at the end of the 20th century in the period when an avant-garde oriented alternative in the 21st century design has been sincerely required overflowed with the fin de siecle phenomenon.

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Volumetric analysis of mucous retention cysts in the maxillary sinus: A retrospective study using cone-beam computed tomography

  • Hung, Kuofeng;Hui, Liuling;Yeung, Andy Wai Kan;Wu, Yiqun;Hsung, Richard Tai-Chiu;Bornstein, Michael M.
    • Imaging Science in Dentistry
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    • v.51 no.2
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    • pp.117-127
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    • 2021
  • Purpose: The aim of this study was to evaluate the volumetric characteristics of mucous retention cysts(MRCs) in the maxillary sinus and to analyze potential associations of MRCs with dentoalveolar pathologies. Materials and Methods: Cone-beam computed tomography (CBCT) scans exhibiting bilateral maxillary sinuses that were acquired from January 2016 to February 2019 were initially screened. A total of 227 scans(454 sinuses) that fulfilled the inclusion criteria were included. The presence, location, and volumetric characteristics of the diagnosed MRCs were evaluated on CBCT images using the 3D-Slicer software platform. The presence of MRCs was correlated with potential influencing factors including age, sex, and dentoalveolar pathology. For MRCs located on the sinus floor, factors with a potential impact on the volume, surface, and diameter were analyzed. Results: An MRC was present in 130 (28.6%) of the 454 sinuses. Most MRCs were located on the sinus walls and floor. The mean MRC volume, surface, and diameter were 551.21±1368.04 mm3, 228.09±437.56 mm2, and 9.63±5.40 mm, respectively. Significantly more sinuses with associated endodontically treated teeth/periapical lesions were diagnosed with an MRC located on the sinus floor. For MRCs located on the sinus floor, endodontic status exhibited a significant association with increased volume, surface, and diameter. Conclusion: Periapical lesions might be a contributing factor associated with the presence and volume of MRCs located on the sinus floor. The 3D-Slicer software platform was found to be a useful tool for clinicians to analyze the size of MRCs before surgical interventions such as sinus floor elevation procedures.

A Study on the generative background and Characteristics of Gesamtkunstwerk Design Theory advocated by Wiener Werkstätte and Josef Hoffmann (빈 공방과 요제프 호프만이 주창한 총체예술(Gesamtkunstwerk) 디자인론의 생성배경과 특성에 관한 연구)

  • Kim, Hong-Ki
    • Korean Institute of Interior Design Journal
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    • v.25 no.1
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    • pp.115-123
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    • 2016
  • In the turn of the twentieth century, Vienna emerged as a great cultural centre that stood at the forefront of developments in music, psychology, and the natural sciences. Equally influential, and still tremendously popular today, are the designs of the Wiener $Werkst{\ddot{a}}tte$ a group that was at the heart of the city's cultural scene and whose collaborators included such luminaries as the architect Josef Hoffman and the designer Koloman Moser under the slogan of Gesamtkunstwerk. The term "Gesamtkunstwerk" was introduced in the romantic period. It describes the desire for and practice of combining various art forms into a whole, such as performances that combine text, visual arts, various design and architecture. Richard Wagner was one of the early theorists of the concept, inspiring many modernist artists. As a co-founder of the Wiener $Werkst{\ddot{a}}tte$, Josef Hoffmann had a decisive influence on modern Viennese architecture and Interior design on the basis of the concept of Gesamtkunstwerk. In this view point, this study is to analyze about the generative background and design characteristics of gesamtkunstwerk advocated Wiener $Werkst{\ddot{a}}tte$. Josef Hoffmann was by all accounts a very successful architect and Interior designer in Vienna. His influence would undoubtedly have been felt simply because of his talent and energy. His special ability to range across multiple domains, coupled with a willingness to collaborate with other artists has created a synthesis and synergy that is compelling to this day.

Soft-tissue Sarcomas in the Asia-Pacific Region: A Systematic Review

  • Ngan, Roger;Wang, Edward;Porter, David;Desai, Jayesh;Prayogo, Nugroho;Devi, Beena;Quek, Richard
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6821-6832
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    • 2013
  • Background: Soft-tissue sarcomas require tailored and multidisciplinary treatment and management. However, little is known about how sarcomas are treated and managed throughout the Asia-Pacific region. Materials and Methods: MEDLINE was systematically searched using prespecified criteria. Publications (previous 10 years) that reported tumour characteristics, treatment patterns, survival outcomes, and/or safety outcomes of patients with soft-tissue sarcoma were selected. Exclusion criteria were studies of patients <18 years of age; ${\leq}10$ patients; countries other than Australia, Hong Kong, Indonesia, Korea, Malaysia, New Zealand, Philippines, Singapore, Taiwan, or Thailand; >20% benign tumours; sarcomas located in bones or joints; gastrointestinal stromal tumour; Kaposi's sarcoma; or not reporting relevant outcomes. Results: Of the 1,822 publications retrieved, 35 (32 studies) were included. Nearly all patients (98%, 1,992/2,024; 31 studies) were treated with surgery, and more studies used adjuvant radiotherapy than chemotherapy (24 vs 17 studies). Survival outcomes and recurrence rates varied among the studies because of the different histotypes, sites, and disease stages assessed. Only 5 studies reported safety findings. Conclusions: These findings highlight the lack of specific data available about soft-tissue sarcomas in the Asia-Pacific region. Better efforts to understand how the sarcoma is managed and treated will help improve patient outcomes in the region.

A numerical and theoretical investigation on composite pipe-in-pipe structure under impact

  • Wang, Yu;Qian, Xudong;Liew, J.Y. Richard;Zhang, Min-Hong
    • Steel and Composite Structures
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    • v.22 no.5
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    • pp.1085-1114
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    • 2016
  • This paper investigates the transverse impact response for ultra lightweight cement composite (ULCC) filled pipe-in-pipe structures through a parametric study using both a validated finite element procedure and a validated theoretical model. The parametric study explores the effect of the impact loading conditions (including the impact velocity and the indenter shape), the geometric properties (including the pipe length and the dimensions of the three material layers) as well as the material properties (including the material properties of the steel pipes and the filler materials) on the impact response of the pipe-in-pipe composite structures. The global impact responses predicted by the FE procedure and by the theoretical model agree with each other closely. The parametric study using the theoretical approach indicates the close relationships among the global impact responses (including the maximum impact force and the maximum global displacement) in specimens with the equivalent thicknesses, proposed in the theoretical model, for the pipe-in-pipe composite structures. In the pipe-in-pipe composite structure, the inner steel pipe, together with the outer steel pipe, imposes a strong confinement on the infilled cement composite and enhances significantly the composite action, leading to improved impact resistance, small global and local deformations.

Effect of Cordyceps militaris on Testosterone Production in Sprague-Dawley Rats

  • Hong, In-Pyo;Choi, Yong-Soo;Woo, Soon-Ok;Han, Sang-Mi;Kim, Hye-Kyung;Lee, Man-Young;Lee, Myung-Ryul;Humber, Richard A.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.23 no.1
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    • pp.143-146
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    • 2011
  • Some of men have been suffered from the insufficient secretion of testosterone causing by physical factors, social and psychological factors. Testosterone is an essential steroid hormone controlling male reproductive function. Alternative medicines in plants, fungi, and insects have been studied to enhance sexuality. $Cordyceps$ species including $Cordyceps$ $sinensis$ (CS) and $C.$ $militaris$(CM) has been used as for the enhancement of sexual functionfor hundreds of years in Far East Asian. In the present study, we determined the effect of fruiting bodies of $C.$ $militaris$ which cultured on bee drone medium (CMD) and brown rice medium (CMB) on testosterone concentration in Sprague-Dawley rats. Eighteen rats per group were housed to regular diet or diet supplemented with CMB and CDD, respectively for 4 weeks. Serum was collected from 6 rats per group. Results showed that changes of the body weight, food and water intake of the rats were not observed in this study. However, both CMB and CDD increased the serum testosterone concentration in rats. Furthermore, CMD significantly stimulated testosterone production (p <0.05) compared to the control. Hence, it suggests that $C.$ $militaris$ fruiting bodymight be developed as a complementary medicine to improve sexual hormones.

Cytokine Reporter Mouse System for Screening Novel IL12/23 p40-inducing Compounds

  • Im, Wooseok;Kim, Hyojeong;Yun, Daesun;Seo, Sung-Yum;Park, Se-Ho;Locksley, Richard M.;Hong, Seokmann
    • Molecules and Cells
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    • v.20 no.2
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    • pp.288-296
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    • 2005
  • Cytokines interleukin (IL) 12 and 23 play critical roles in linking innate and adaptive immune responses. They are members of heterodimeric cytokines, sharing a subunit p40. Although IL12/23 p40 is mainly induced in macrophages and dendritic cells (DCs) after stimulation with microbial Toll-like receptor ligands, methods to monitor the cells that produce IL12/23 p40 in vivo are limited. Recently, the mouse model to track p40-expressing cells with fluorescent reporter, yellow fluorescent protein, has been developed. Macrophages and DCs from these mice faithfully reported p40 induction using the fluorescent marker. Here we took advantage of these reporter mice to screen bio-compounds for p40-inducing activity. After screening hundreds of compounds, we found several extracts inducing IL12/23 p40 gene expression. Treatment of DCs with these extracts induced the expression of MHC class II and co-stimulatory molecules, which implies that these might be useful as adjuvants. Next, the in vivo target immune cells of candidate compounds were examined. The reporter system can be useful to identify cells producing IL12 or IL23 in vivo as well as in vitro. Thus, our cytokine reporter system proved to be a valuable reagent for screening for immunostimulatory molecules and identification of target cells in vivo.