• Nutrition Research and Practice
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• 제7권6호
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• pp.453-459
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• 2013

The abnormal content of blood lipids often results in metabolic diseases, such as hyperlipidemia and obesity. Many agents, including natural sources from traditional food, have been developed to regulate the blood lipid contents. In this study, we examined the anti-hyperlipidemic activity of Rhynchosia nulubilis seeds pickled with brown rice vinegar (RNSpBRV), a Korean traditional pickled soybean food. Since RNSpBRV is made of R. nulubilis seeds (RNS) soaked in brown rice vinegar (BRV), we compared the anti-adipogenic activity between RNS, BRV and solid fraction of RNSpBRV (SF-RNSpBRV), liquid fraction of RNSpBRV (LF-RNSpBRV). For this, the inhibitory effect of lipid accumulation in 3T3-L1 adipocyte was checked by adding methanol extracts of mixed RNS and BRV, LF-RNSpBRV, and SF-RNSpBRV. The addition of each methanol extract up to 1 mg/ml showed no cytotoxicity on 3T3-L1 adipocyte, and approximately 20% of the lipid droplet formation was suppressed with the methanol extract of BRL or SF-RNSpBRV. The highest suppression (42.1%) was achieved with LF-RNSpBRV. In addition, mice fed a high fat diet (HFD) supplemented with 5% RNSpBRV powder led to increased high density lipoprotein (HDL) cholesterol and lower blood glucose, triglyceride, and total cholesterol compared to mice fed with a HFD diet only. Interestingly, the size of the epididymis cells gradually decreased in HFD + 1% RNSpBRV and HFD + 5% RNSpBRV-fed mice if compared those of HFD-fed mice. Taken together, these results provide evidence that RNSpBRV has a regulatory role in lipid metabolism that is related to hyperlipidemia.

• Nutritional Sciences
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• 제9권2호
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• pp.97-105
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• 2006

Beans are well known to be high-protein diets. Bean seeds contain arginine, lysine, or glycine-rich proteins which are effective to maintain lower glucose levels. In this study, the synergistic effect of fermented small soybean (Chounggukjang) and mulberry leaf on metabolism and hexokinase activity was investigated in streptozotocin (STZ)-induced diabetic rats. We divided 8 groups as follows: non-diabetic rat group fed with only water diet (NC: control), and STZ-induced diabetic rat groups fed with water (DC), fermented Rhynchosia Nulubilis (Bbc), fermented Glycine max Merr (Ybc), Bbc and YBc (BYbc), mulberry leaf and Bbc (MBbc), mulberry leaf and Ybc (MYbc), or the mulberry leaf, Bbc, and Ybc (MBYbc). Diabetes mellitus was induced in rats by subcutaneous STZ administration (70 mg/kg of body weight). All diet groups were fed with Chounggukjang in a powder form. Three ml of Chounggukjang solution (0.75 mg per gram of body weight) dissolved in distilled water was orally administered to all rat groups after STZ administration except for NC rat group. In groups fed with fermented soybeans, the body weight (increased), food efficiency ratio (FER) (increased), glucose level (decreased) and hexokinase (HK) activity (increased) significantly differed to NC. Among them, particularly in the groups fed with both fermented soybeans and mulberry leaf, kidney weight significantly decreased, whereas HK activity significantly increased compared to DC. These results suggest that Chounggukjang of both fermented soybeans and mulberry leaf is potentially used as an effective functional food to prevent diabetes complications.

• 환경생물
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• 제34권4호
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• pp.346-352
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• 2016

팥바구미(Callosobruchus chinensis L.)의 산란 선호성 및 성장 조사를 위해 6가지 콩과식물 종자인 팥, 흑태, 백태, 서리태, 서목태, 강낭콩을 선택, 실험을 하였다. 각 종자당 산란수는 팥 1.23개, 서목태 1.13개, 서리태 1.05개, 백태 0.69개, 흑태 0.61개로 나타났으며, 둘째 날(48 h) 최고 산란수, 넷째날(96 h) 최저 산란을 나타냈다. 유충 성장기간이 기주식물에 따라 2배 이상 증가하는 것으로 나타났다. 우화율은 팥, 서리태, 흑태, 백태, 서목태(83.33%, 28.23%, 27.87%, 20.44%, 11.59%) 순으로 나타났으며, 모든 종자에서 팥과 3배 이상의 차이를 보였다. 성충 수명은 암컷보다 수컷이 대부분 길었고 암컷의 경우 팥 9.43일, 서리태 8.86일, 흑태 7.88일, 백태 7.17일, 서목태 6.80일로 나타났다. 각 성충의 무게는 암수 모두 팥에서 가장 무겁고, 수컷은 서목태, 암컷은 백태에서 최소 무게를 나타냈다. 결과적으로, 팥바구미는 팥 이외의 기주에서는 산란, 우화율, 성충 수명, 성충 무게 감소가 나타났고 반면 우화시기도 지연되었다. 한편 강낭콩에서 산란과 우화는 전혀 없었는데 이것은 강낭콩 종피에 산란과 우화 억제물질이 있음을 시사하며, 이러한 물질의 활용으로 콩바구미과 피해를 조절할 수 있을 것으로 여겨진다.