• Biomolecules & Therapeutics
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• v.28 no.3
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• pp.272-281
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• 2020

Environmental agents, including viral and bacterial infectious agents, are involved in the alteration of physicochemical and biological parameters in the nasal epithelium. Hyaluronan (HA) has an important role in the regulation of tissue healing properties. High molecular weight HA (HMW-HA) shows greater anti-inflammatory responses than medium molecular weight HA (MMW-HA) and low molecular weight HA (LMW-HA). We investigated the effect of HMW-HA, MMW-HA and LMW-HA on the regulation of physicochemical and biological parameters in an "in vitro" model that might mimic viral infections of the nasal epithelium. Human nasal epithelial cell line RPMI2650 was stimulated with double-stranded RNA (dsRNA) Poly(I:C) for 5 days in air-liquid-interface (ALI) culture (3D model of airway tissue). dsRNA Poly(I:C) treatment significantly decreased transepithelial electrical resistance (TEER) in the stratified nasal epithelium of RPMI2650 and increased pH values, rheological parameters (elastic G' and viscous G''), and Muc5AC and Muc5B production in the apical wash of ALI culture of RPMI2650 in comparison to untreated cells. RPMI2650 treated with dsRNA Poly(I:C) in the presence of HMW-HA showed lower pH values, Muc5AC and Muc5B production, and rheological parameters, as well as increased TEER values in ALI culture, compared to cells treated with Poly(I:C) alone or pretreated with LMW-HA and MMW-HA. Our 3D "in vitro" model of epithelium suggests that HMW-HA might be a coadjuvant in the pharmacological treatment of viral infections, allowing for the control of some physicochemical and biological properties affecting the epithelial barrier of the nose during infection.

• Earthquakes and Structures
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• v.17 no.2
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• pp.131-141
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• 2019

Structural control systems have uncertainties in their structural parameters and control devices which by using reliability analysis, uncertainty can be modeled. In this paper, reliability of controlled structures equipped with semi-active Magneto-Rheological (MR) dampers is investigated. For this purpose, at first, the effect of the structural parameters and damper parameters on the reliability of the seismic responses are evaluated. Then, the reliability of MR damper force is considered for expected levels of performance. For sensitivity analysis of the parameters exist in Bouc- Wen model for predicting the damper force, the importance vector is utilized. The improved first-order reliability method (FORM), is used to reliability analysis. As a case study, an 11-story shear building equipped with 3 MR dampers is selected and numerically obtained experimental data of a 1000 kN MR damper is assumed to study the reliability of the MR damper performance for expected levels. The results show that the standard deviation of random variables affects structural reliability as an uncertainty factor. Thus, the effect of uncertainty existed in the structural model parameters on the reliability of the structure is more than the uncertainty in the damper parameters. Also, the reliability analysis of the MR damper performance show that to achieve the highest levels of nominal capacity of the damper, the probability of failure is greatly increased. Furthermore, by using sensitivity analysis, the Bouc-Wen model parameters which have great importance in predicting damper force can be identified.

• Korea-Australia Rheology Journal
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• v.18 no.4
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• pp.191-197
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• 2006

The measurement of the compressional rheological parameters for an aggregated particulate suspension is described. The parameters include the compressive yield stress and hindered settling function, describing the extent and rate of dewatering respectively. The variation of these parameters with shear rate and time of shear is also considered in the light of their sensitivity to low shear rates, with particular reference to the case of flocculated particulate suspensions. The latter is seen to be important in the future development of a comprehensive understanding of compressive rheology of aggregated particulate suspensions in industrial applications such as thickening, filtration and centrifugation.

• Journal of the Korea Institute of Building Construction
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• v.20 no.5
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• pp.399-407
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• 2020

The aim of the research is to provide the boundary conditions for segregation of normal strength grade and high fluidity concrete mixture (so called mid-fluidity concrete) with rheology parameters. Since the normal strength grade concrete mixture has a relatively high water-to-cement ratio and no SCMs, it is easy to be segregated when superplasticizer is added. Hence, to achieve the mid-fluidity concrete of normal strength grade and high fluidity, preventing segregation of the mixture is inevitable. In this research, using two superplasticizers with different solid concentrations, the flow behaviors and rheological behaviors were assessed by increasing fluidity until the segregation happened. According to the experiment in this research, an unusual behavior in rheology parameters was observed when the concrete mixture started to be segregated. From this results and report, it is expected to contribute on the definition of segregation with rheological test methods.

• Journal of the Korea Concrete Institute
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• v.27 no.5
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• pp.511-519
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• 2015

Methods such table flow, slump and outflow time have used to be as a main evaluation criteria regards to fluidity of concrete. Since those methods mentioned above have some inaccuracies which are up to its condition of test. Studies that evaluate fluidity applying the rheology has increased its portion in this field. Meanwhile, demands for AAS binder have been increased in accordance with its demand for this market, studies for rheology of AAS binder are little though. Therefore, this paper mainly deals a rheological peculiarity of AAS binder according to its condition of W/B ratio and alkali activators. The fluidity of AAS paste was evaluated with the index of table flow and outflow time. And shear stress following its shear rate was analyzed through rheological test. Rheological parameters were deduced through this rheological test of Bingham model and analyzed its interrelation with fluidity test. As the final outcome, it proposed the interrelation among table flow, yield stress, viscosity and outflow time. In basis of this study, we would like to suggest a reference for mixing AAS mortars and concretes.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.5
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• pp.1897-1905
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• 2013

Rheological properties such as yield stress and viscosity is the main parameters to determine the fluidity of the debris flow. In this study, several series of rheometer tests were performed to investigate rheological properties of fine-grained soil samples with various sand contents and various liquidity indices. Test results indicated that the general shape of the flow curves for fine-grained soils had characteristics of a shear thinning fluid, with a decrease in viscosity as shear rate increases. The yield stress and viscosity of fine-grained soil samples with same sand content gradually decreased as the liquidity index increased. At the same liquidity index, yield stress and viscosity of fine-grained soil increased with an increase in sand content. The yield stress and viscosity of fine-grained soil greatly decreased with a slight increase in water content. Also, the yield stress and viscosity tend to increase with increasing concentration by volume($C_v$) of the fluid matrix. The values of the four coefficients ${\alpha}_1$, ${\alpha}_2$, ${\beta}_1$, and ${\beta}_2$ were obtained by regression analysis for each fine-grained soil.

• Journal of Dental Rehabilitation and Applied Science
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• v.24 no.3
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• pp.311-316
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• 2008

Calcium phosphate cement (CPC) has been used as bone substitute successfully due to good biocompatibility and osteoconductivity. One of the important mechanical characteristics of CPC is flowablility, which can be evaluated by measuring rheological parameters. However, there have been few studies that measured rheological properties of CPC. The purpose of this study was to evaluate the rheological properties of CPC paste mixed with 2 kinds of setting solutions, 2% hydroxyprophyl methylcellulose (HPMC) and 35% polyacrylic acid (PAA). The CPC used was dicalcium phosphate dihydrate (DCPD). Rheological properties of CPC paste were measured using rheometer. The statistical analysis was carried out with Mann-whitney test with Bonferronis collection. CPC with both setting solutions showed shear thinning behavior. CPC with 2% HPMC showed signigicantly higher complex viscosity than CPC with 35% PAA(p<0.05).

• Applied Biological Chemistry
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• v.38 no.4
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• pp.353-358
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• 1995

The influence of dry-heat treatment($130{\sim}220^{\circ}C$) on the gelatinization and rheological properties of corn starch(11.4% moisture) was examined. The enthalpy of gelatinization measured by differential scanning calorimetry decreased above $190^{\circ}C$. The viscosity of starch by alkali gelatinization increased as the heating temperature rised. All the values including peak viscosity on amylograms and shear stress, apparent viscosity, consistency index and yield stress of thermal-gelatinized starch dispersion showed decreasing tendencies with increasing of heating temperature from above $170^{\circ}C$ compared with those of raw starch. The apparent viscosity and yield stress of all the samples thermal-gelatinized at $90^{\circ}C$ were increased considerably with process of gelatinization time and especially their rapid increase at the early stage was observed in the $190^{\circ}C$ sample. But all the rheological parameters of $220^{\circ}C$ sample recorded very low values compared with those of the others.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.28 no.4
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• pp.397-400
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• 1995

Effects of rheological parameters, such as shear rate, temperature, concerntration, salts on the apparent viscosity of chitosan(deacetylation degree: $84\%$, Mw: 267,000) dissolved in acetate buffer(pH 4.5) were investigated. Rheologiral properties of chitosan solution from cuticle of red snow crab (Chinonecetes japonicus) are as follows. $0.5\%$ chitosan in 0.1M acetate buffer (pH 4.5) solution showed Bingham flow having hysteresis loop. It's flow equation was $\sigma=0.757+19.6_\gamma(r^2=0.99)$. The viscosity of chitosan solution is exponentially increased with its concentration, and showed Arrhenius dependence with respect to the temperature $(10^{\circ}C-40^{\circ}C).$ When various salts were added to chitosan solution, the viscosity decreased as the concentration of counterion increased. But the type ot counterions itself does not have any significant effects on the viscosity.

• Bulletin of the Korean Chemical Society
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• v.26 no.9
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• pp.1403-1409
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• 2005

A sensitive and selective electrochemical method was developed for the amperometric determination of ascorbic acid (AA) at a glassy carbon electrode (GCE) modified with single-wall carbon nanotubesdihexadecyl hydrogen phosphate (SWNT-DHP) composite film. The SWNT-DHP composite film modified GCE was characterized with SEM. The SWNT-DHP composite film modified GCE exhibited excellent electrocatalytic behaviors toward the oxidation of AA. Compared with the bare GCE, the oxidation current of AA increased greatly and the oxidation peak potential of AA shifted negatively to about -0.018 V (vs. SCE) at the SWNT-DHP composite film modified GCE. The experimental parameters, which influence the oxidation current of AA, were optimized. Under the optimal conditions, the amperometric measurements were performed at a applied potential of -0.015 V and a linear response of AA was obtained in the range from 4 ${\times}$ $10^{-7}$ to 1 ${\times}$ $10^{-4}$ mol $L^{-1}$ and with a limit of detect (LOD) of 1.5 ${\times}$ $10^{-7}$ mol $L^{-1}$. The interferences study showed that the SWNT-DHP composite film modified GCE exhibited good sensitivity and excellent selectivity in the presence of high concentration uric acid and dopamine. The proposed procedure was successfully applied to detect AA in human urine samples with satisfactory results.