• Title/Summary/Keyword: Review Grade

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Role of A-TIG process in joining of martensitic and austenitic steels for ultra-supercritical power plants -a state of the art review

  • Bhanu, Vishwa;Gupta, Ankur;Pandey, Chandan
    • Nuclear Engineering and Technology
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    • v.54 no.8
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    • pp.2755-2770
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    • 2022
  • The need for Dissimilar Welded Joint (DWJ) in the power plant components arises in order to increase the overall efficiency of the plant and to avoid premature failure in the component welds. The Activated-Tungsten Inert Gas (A-TIG) welding process, which is a variant of Tungsten Inert Gas (TIG) welding, is focus of this review work concerning the DWJ of nuclear grade creep-strength enhanced ferritic/martensitic (CSEF/M) steels and austenitic steels. A-TIG DWJs are compared with Multipass-Tungsten Inert Gas (M-TIG) DWJ based on their mechanical and microstructural properties. The limitations of multipass welding have put A-TIG welding in focus as A-TIG provides a weld with increased depth of penetration (DOP) and enhanced mechanical properties. Hence, this review article covers the A-TIG welding principle and working parameters along with detailed analysis of role played by the flux in welding procedure. Further, weld characteristics of martensitic and austenitic steel DWJ developed with the A-TIG welding process and the M-TIG welding process are compared in this study as there are differences in mechanical, microstructural, creep-related, and residual stress obtained in both TIG variants. The mechanics involved in the welding process is deliberated which is revealed by microstructural changes and behavior of base metals and WFZ.

Effectiveness of Acupuncture for Laryngopharyngeal Reflux Disease: A Systematic Review and Meta-Analysis

  • Jihun Oh;Jaewoo Yang;Jungmin Yang;Minsoo Kang;Sukyoung Kim;Minjun Lee;Jinwoong Lim
    • Journal of Acupuncture Research
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    • v.40 no.3
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    • pp.188-200
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    • 2023
  • Laryngopharyngeal reflux (LPR) disease is a condition in which the stomach contents return to the larynx and pharynx via the esophagus, causing mucosal injury. While conventional treatments, such as proton pump inhibitors, have limitations, acupuncture has been shown to reduce LPR symptoms. However, its effectiveness has not been systematically assessed. This study aimed to systematically evaluate the effectiveness of acupuncture in treating LPR. We review 10 electronic databases with a consistent search strategy, and 2 independent reviewers screened the articles based on the inclusion and exclusion criteria. This study selected and analyzed 7 randomized controlled trials after the screening to assess primary outcomes, including reflux symptom index and reflux finding score, and secondary outcomes, including upper and lower esophageal sphincter pressure. The results revealed the statistically significant effectiveness of acupuncture in combination with conventional treatment in reducing LPR symptoms compared with conventional treatment alone. The most commonly used acupuncture points were CV22, ST36, and LR3. However, the meta-analysis demonstrated low reliability, as assessed using the GRADE Tool. Further research is needed to improve the evidence and draw clear conclusions regarding the clinical use of acupuncture for treating LPR.

Effect of intracanal cryotherapy on postoperative pain after endodontic treatment: systematic review with meta-analysis

  • Fernanda Garcias Hespanhol;Ludmila Silva Guimaraes;Livia Azeredo Alves Antunes;Leonardo Santos Antunes
    • Restorative Dentistry and Endodontics
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    • v.47 no.3
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    • pp.30.1-30.15
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    • 2022
  • Objectives: This study aimed to evaluate the effectiveness of final irrigation with cold saline solution after endodontic treatment compared with saline solution at room temperature against postoperative pain following endodontic treatment. Materials and Methods: A broad search was performed in the PubMed, Web of Science, Scopus, Cochrane Library, Virtual Health Library (LILACS), and Grey Literature databases. Two independent reviewers performed data extraction, risk of bias using the Cochrane methodology, and certainty of evidence using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. Results: Eight studies were included in qualitative synthesis. Intracanal cryotherapy favored the reduction of postoperative pain in the systematic review. Four studies were included in meta-analyses. The meta-analysis showed that intracanal cryotherapy reduced postoperative pain in teeth with symptomatic apical periodontitis (SAP) at 24 hours. There was no association between intracanal cryotherapy and control (room temperature) groups in teeth with normal periapical tissue with respect to postoperative pain at 24 hours and 48 hours. Conclusions: Intracanal cryotherapy was effective in reducing postoperative pain after endodontic treatment in teeth with SAP.

Effect of Acupuncture and Moxibustion for Vitiligo: A Scoping Review of Randomized Controlled Trials (백반증의 침구(鍼灸) 치료 효과: 무작위 대조 시험에 대한 주제 범위 문헌 고찰)

  • Do Kyung Han;Jeewon Shon;Won Gun An
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.36 no.4
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    • pp.145-155
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    • 2023
  • Objectives : The aim of this study is to review the effect of acupuncture/moxibustion on vitiligo. Methods : Using 5 databases(Pubmed, EMBASE, Cochrane Library, RISS, OASIS) clinical studies about effect of acupuncture/moxibustion on vitiligo were searched. Only randomized controlled trials(RCTs) were selected to analyze. Results : Total 235 studies were searched. After screening those studies 5 studies were selected from china and Iran. 3 studies used effective rate to measure the effect of acupuncture for vitiligo. 1 study used Vitiligo Area Scoring Index(VASI) and 1 study assessed 4 grade of repigmentation to prove acupuncture's effect on vitiligo. All studies showed repigmentation in acupuncture/moxibustion group. Adverse effects reported in the five studies were temporary erythema, itching, and dryness. Conclusions : These findings suggest that acupuncture and moxibustion can be considered a safe treatment for vitiligo. However, due to the small number of RCTs conducted on acupuncture and moxibustion for vitiligo, more RCTs should be conducted to confirm the effectiveness of acupuncture and moxibustion for vitiligo.

Can carbamide peroxide be as effective as hydrogen peroxide for in-office tooth bleaching and cause less sensitivity? A systematic review

  • Patrick Wesley Marques de Boa;Kaiza de Sousa Santos;Francisca Jennifer Duarte de Oliveira;Boniek Castillo Dutra Borges
    • Restorative Dentistry and Endodontics
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    • v.49 no.2
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    • pp.14.1-14.13
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    • 2024
  • This study aimed to answer the question through a systematic review: Can carbamide peroxide be as effective as hydrogen peroxide and cause less in-office bleaching sensitivity? A literature survey was performed in PubMed/MEDLINE, Embase, Scopus, ISI Web of Science, and gray literature. Primary clinical trials that compared the efficacy or the in-office bleaching sensitivity between carbamide and hydrogen peroxides were included. The risk of bias was evaluated using the RoB2. The certainty of the evidence was assessed using the GRADE approach. DPI training significantly improved the mean scores of the dental undergraduates from 7.53 in the pre-DPI-training test to 9.01 in the post-DPI-training test (p < 0.001). After 6 weeks, the mean scores decreased marginally to 8.87 in the retention test (p = 0.563). DPI training increased their confidence level from 5.68 pre-DPI training to 7.09 post-DPI training. The limited evidence suggests that the 37% carbamide peroxide may be similarly effective to the 35% hydrogen peroxide for bleaching teeth in-office and causes less bleaching sensitivity. However, more well-designed split-mouth clinical trials are necessary to strengthen the evidence.

Evaluation of the Readability and Suitability of Printed Educational Materials on Metabolic Syndrome (대사증후군 교육 인쇄물의 이독성과 적합성 평가)

  • Kim, Jung Eun;Yang, Sook Ja
    • Journal of Korean Public Health Nursing
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    • v.30 no.1
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    • pp.149-163
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    • 2016
  • Purpose: The aim of this study was to assess the readability and suitability of printed educational materials related to metabolic syndrome in South Korea. Methods: Data were collected on 15 educational materials on metabolic syndrome from public health centers in Seoul. The 9 Graded Korean Vocabulary Classification and Korean version of SAM (Suitability Assessment of Materials) were used for the readability evaluation and the suitability evaluation respectively. Results: Overall average of the readability was 3.0th grade level. The percentage of 1st to 4th grade words was 79.4%. The printed educational materials on metabolic syndrome were written according to recommended reading levels. In suitability assessment, 2 out of 15 materials(13.3%) were scored as superior, 12 materials(80.0%) were scored as adequate and only 1 (6.7%) was scored as inadequate. The total average score of suitability was adequate. However, there are limitations in "summary and review" and "context is given first" due to limited writing pages. Conclusion: Readability and suitability of educational materials for metabolic syndrome were evaluated as adequate level. However, future health educational materials should be evaluated for readability via different factors including length of sentences, numbers of sentences, and structure of sentences. In addition, for easier understanding and motivation of readers, materials should use summary & review, context and proper interaction.

Review of the Unit on the Mixed Calculations in the 4th Grade (초등학교 4학년 혼합계산 지도에 대한 고찰)

  • Ko, Jung Hwa
    • Journal of Educational Research in Mathematics
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    • v.22 no.4
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    • pp.477-494
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    • 2012
  • This study is to review the content organization and developmental ways of the unit on the mixed calculations and explore the alternatives on the basis of students' responsive examples and error patterns with relation to the mixed calculations, mnemonics of PEMDAS and historical context with relation to the order of operations. Then I analyzed the textbook and manual for teachers of the unit of mixed calculations of fourth grade and improvement about teaching the mixed calculations. First, I pointed out illogical connection between practical problem and rules of order of operations. Second, I suggested constructing a textbook by considering conventional character of order of operations. Third, I pointed out the importance of structural understanding of an expression of mixed calculations and various strategies with relation to teaching and learning. This study is suggestive for textbook development of the mixed calculations.

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Human Papillomavirus Genotype Distribution among Thai Women with High-Grade Cervical Intraepithelial Lesions and Invasive Cervical Cancer: a Literature Review

  • Kietpeerakool, Chumnan;Kleebkaow, Pilaiwan;Srisomboon, Jatupol
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.13
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    • pp.5153-5158
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    • 2015
  • Infection with high-risk human papillomavirus (HR-HPV) is an essential cause of cervical cancer. Because of substantial geographical variation in the HPV genotype distribution, data regarding HPV type-specific prevalence for a particular country are mandatory for providing baseline information to estimate effectiveness of currently implemented HPV-based cervical cancer prevention. Accordingly, this review was conducted to evaluate the HR-HPV genotype distribution among Thai women with precancerous cervical lesions i.e. cervical intraepithelial neoplasia grade 2-3 (CIN 2-3), adenocarcinoma in situ (AIS), and invasive cervical cancer by reviewing the available literature. The prevalence of HR-HPV infection among Thai women with CIN 2-3 ranged from 64.8% to 90.1% and the three most common genotypes were HPV 16 (38.5%), HPV 58 (20.0%), and HPV 18 (5.5%). There were high squamous cell carcinoma/CIN 2-3 prevalence ratios in women with CIN 2-3 infected with HPV 33 and HPV 58 (1.40 and 1.38, respectively), emphasizing the importance of these subtypes in the risk of progression to invasive cancer among Thai women. Data regarding the prevalence and genotype distribution of HR-HPV in Thai women with AIS remain unavailable. Interesting findings about the distribution of HPV genotype in cervical cancer among Thai women include: (1) a relatively high prevalence of HPV 52 and HPV 58 in invasive squamous cell carcinoma; (2) the prevalence of HPV 18-related adenocarcinoma is almost double thepreviously reported prevalence, and (3) 75% of neuroendocrine carcinomas are HPV18-positive when taking into account both single and multiple infections.

Does photobiomodulation on the root surface decrease the occurrence of root resorption in reimplanted teeth? A systematic review of animal studies

  • Theodoro Weissheimer;Karolina Frick Bischoff;Carolina Horn Troian Michel;Bruna Barcelos So;Manoela Domingues Martins;Matheus Albino Souza;Ricardo Abreu da Rosa;Marcus Vinicius Reis So
    • Restorative Dentistry and Endodontics
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    • v.48 no.3
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    • pp.24.1-24.16
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    • 2023
  • This review aimed to answer the following question "Does photobiomodulation treatment of the root surface decrease the occurrence of root resorption in reimplanted teeth?" Electronic searches were performed in the MEDLINE/PubMed, Cochrane Library, Scopus, Web of Science, Embase, and Grey Literature Report databases. Risk of bias was evaluated using SYRCLE Risk of Bias tool. The Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) tool was used to assess the certainty of evidence. In total, 6 studies were included. Five studies reported a reduced occurrence of root resorption in teeth that received photobiomodulation treatment of the root surface prior to replantation. Only 1 study reported contradictory results. The photobiomodulation parameters varied widely among studies. GRADE assessment showed a low certainty of evidence. It can be inferred that photobiomodulation treatment of the root surface prior to replantation of teeth can reduce the occurrence of root resorption. Nonetheless, further clinical studies are needed.

Effectiveness and Safety of Pemetrexed Versus Docetaxel as a Treatment for Advanced Non-small Cell Lung Cancer: a Systematic Review and Meta-analysis

  • Di, Bao-Shan;Wei, Kong-Ping;Tian, Jin-Hui;Xiao, Xiao-Juan;Li, Yan;Zhang, Xu-Hui;Yu, Qin;Yang, Ke-Hu;Ge, Long;Huang, Wen-Hui;Zhang, Fang-Wa
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3419-3424
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    • 2014
  • Background: Our aim was to conduct a meta-analysis to compare the efficacy and safety of pemetrexed and docetaxel for non-small cell lung cancer (NSCLC). Materials and Methods: We systematically searched the Cochrane Library, PubMed, Embase, China Biology Medicine Database for randomized controlled trials (RCTs) comparing the efficacy and toxicities of pemetrexed versus docetaxel as a treatment for advanced NSCLC. We limited the languages to English and Chinese. Two reviewers independently screened articles to identify eligible trials according to the inclusion and exclusion criteria and assessed the methodological quality of included trials, and then extracted data. The meta-analysis was performed using STATA12.0. Results: Six RCTs involving 1,414 patients were identified. We found that there was no statistically significant differences in overall response rate, survival time, progression-free survival, disease control rate, and 1-2yr survival rate (p>0.050) but it is worthy of mention that patients in the pemetrexed arms had significantly higher 3-yr survival rate (P=0.002). With regard to the grade 3 or 4 hematological toxicity, compared with docetaxel, pemetrexed led to lower rate of grade 3-4 febrile neutropenia, neutropenia, and leukocyts toxicity (p<0.001). There was no significant difference in anemia between the two arms (p=0.08). In addition, pemetrexed led to higher rate of grade 3-4 thrombocytopenia toxicity (p=0.03). As for the non-hematological toxicities, compared with docetaxel, pemetrexed group had lower rate of grade 3-4 diarrhea and alopecia. Conclusions: Pemetrexed was almost as effective as docetaxel in patients with advanced NSCLC. At the same time, pemetrexed might increase the 3-yr survival rate. As for safety, pemetrexed led to lower rate of grade 3-4 febrile neutropenia, neutropenia, leukocytes, diarrhea and alopecia toxicity. However, it was associated with a higher rate of grade 3-4 thrombocytopenia.