• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제49권3호
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• pp.135-141
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• 2023

Objectives: This study aimed to develop and validate machine learning (ML) models using H₂O-AutoML, an automated ML program, for predicting medication-related osteonecrosis of the jaw (MRONJ) in patients with osteoporosis undergoing tooth extraction or implantation. Patients and Methods: We conducted a retrospective chart review of 340 patients who visited Dankook University Dental Hospital between January 2019 and June 2022 who met the following inclusion criteria: female, age ≥55 years, osteoporosis treated with antiresorptive therapy, and recent dental extraction or implantation. We considered medication administration and duration, demographics, and systemic factors (age and medical history). Local factors, such as surgical method, number of operated teeth, and operation area, were also included. Six algorithms were used to generate the MRONJ prediction model. Results: Gradient boosting demonstrated the best diagnostic accuracy, with an area under the receiver operating characteristic curve (AUC) of 0.8283. Validation with the test dataset yielded a stable AUC of 0.7526. Variable importance analysis identified duration of medication as the most important variable, followed by age, number of teeth operated, and operation site. Conclusion: ML models can help predict MRONJ occurrence in patients with osteoporosis undergoing tooth extraction or implantation based on questionnaire data acquired at the first visit.

• Archives of Plastic Surgery
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• 제46권3호
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• pp.235-240
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• 2019

Background The efficacy of Limberg flap reconstruction for pilonidal sinus with acute abscess remains unclear. This study aimed to compare outcomes after Limberg flap reconstruction for pilonidal sinus disease with and without acute abscess. A secondary objective was to perform a review of the literature on the topic. Methods A retrospective chart review was conducted of all patients who underwent excision and Limberg flap reconstruction for pilonidal sinus from 2009 to 2018. Patient demographics, wound characteristics, and complication rates were reviewed and analyzed. Results Group 1 comprised 19 patients who underwent Limberg flap reconstruction for pilonidal sinus disease without acute abscess and group 2 comprised four patients who underwent reconstruction for pilonidal sinus disease with acute abscess. The average defect size after excision was larger in group 2 than group 1 ($107.7{\pm}60.3cm^2$ vs. $61.4{\pm}33.8cm^2$, respectively). There were no recurrences, seromas or cases of flap necrosis postoperatively. There was only one revision surgery needed for evacuation of a postoperative hematoma in group 1. There were comparable rates of partial wound dehiscence treated by local wound care, hematoma, need for revision surgery and minor infection between group 1 and group 2. Conclusions Limberg flap reconstruction for pilonidal sinus in the setting of acute abscess is a viable option with outcomes comparable to that for disease without acute abscess. This practice will avoid the pain and cost associated with a prolonged local wound care regimen involved in drainage of the abscess prior to flap reconstruction.

• Journal of Acupuncture Research
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• 제39권1호
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• pp.29-35
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• 2022

Background: Electronic moxibustion has the advantage of temperature control and maintenance, and overcomes the limitations of the existing moxibustion process without the use of the combustion process. However, as the application of electronic moxibustion in clinical practice has increased, safety issues are emerging. Methods: Clinical cases of electronic moxibustion treatment for knee osteoarthritis where burns occurred were collected. In addition, adverse events reported in clinical studies using electronic moxibustion for patients with knee osteoarthritis were collected from studies retrieved from Korean and international databases. Results: There were 3 cases of superficial 2^nd degree burns retrospectively collected through chart reviews. Among the selected 5 studies for literature review, 2 studies reported adverse events which were burns milder than those reported in these 3 cases in this retrospective case review. Conclusion: Since the risk of superficial 2^nd degree burn was discovered in the cases reviewed, further research on safe electronic moxibustion treatment is required without compromising the effectiveness of moxibustion.

• 한국임상약학회지
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• 제16권2호
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• pp.81-85
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• 2006

Community acquired pneumonia(CAP) is the most prevalent disease among pneumonia patients and progressed to severe pneumonia. A retrospective study was performed to evaluate antibiotic regimens according to guidelines of Infectious Disease Society of America. From January to October 2005, chart review of 50 patients with CAP was peformed in terms of microbiology and laboratory data of each regimen. Temperature, WBC count, ALT, AST and alkaline phosphatase of each patient were examined for liver toxicity. In three patients received levofloxacin appeared to have normalized temperature and improved cough. The patients who received cefmetazole -aminoglycoside appeared to have worsen LFT(Liver function test). Many patients in flomoxef-aminoglycoside group received mechanical ventilation because of the basis diseases like tuberculosis, diabetes mellitus and hypertension. In conclusion, antibiotic therapy for the treatment of CAP should be selected according to tolerance, bacteria and severity of disease.

• 한방안이비인후피부과학회지
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• 제28권2호
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• pp.112-120
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• 2015

Purpose : To observe effects of TKM (Traditional Korean Medicine) treatment for 2 patients who had verruca plana after having laser epilation of leg hair. Methods : We did retrospective chart review for 2 verucca plana patients who had been treated by TKM. TKM treatment included herbal treatment, herbal acupuncture and herbal ointment. Results : After TKM treatment, the patients' verucca plana remarkably disappeared and there was no recurrence. Conclusion : This study suggest that TKM may be an effective treatment for verucca plana.

• 대한물리치료과학회지
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• 제5권4호
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• pp.809-816
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• 1998

This study was conducted to evaluated the effects adding continuous passive motion(CPM) each day to the entire postoperative program of patients who received a total knee replacement(TKR). A retrospective chart review was completed for 31 patients(12 with bilateral involvement, totaling 44 knees)who received a TKR between 1996 and 1998. The data analysis compared the following variables for 28 patients who received CPM and 16 patients who received no CPM: the length of hospital stay(LOS), the frequency of postoperative complications, the number of post-operative days(PODs) range of motion (ROM). The CPM Group showed significant decreases in the frequency of complication(p<0.05), the LOS(p < 0.05), and No difference was demonstrated in the ROM of the two groups. We concluded that CPM was an effective adjunct to physical therapy care of patients undergoing total knee replacement.

• 대한물리치료과학회지
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• 제1권1호
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• pp.129-134
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• 1994

The purpose of this study is to conduct a retrospective chart audit of initial physical therapy evaluation to determine the incidence of sitting imbalance and its relationship to the side of weakness in hemiparetic patients. A review of the records of 36 patients revealed that the left side was predominantly affected in 17 patients and the right side in 19 patients. Ages, time since onset, and proportion of men and women did not difer between the left and right hemiparetic patients. About half patients(52.8%) could sit independently, but 64.7% of those with left-sided weak-ness and 31.6% of those with right-sided weakness could not. A chi-sequare analysis revealed a significant relationship between the side of weakness and independent sitting balance(p<0.1). Patients with left hemiplegia are more likely to have difficulty with independent sitting balance(p<0.1). Patient with left hemiplegia are more likely to have difficulty with independent sitting than patients with right hemiplegia, which may affect their progress in rehabilitation.

• 대한한방부인과학회지
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• 제32권3호
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• pp.116-127
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• 2019

Objectives: The purpose of this study is to evaluate the effects of Gamitonggyung-tang on Primary Dysmenorrhea. Methods: We treated 33 cases of primary dysmenorrhea patients with Gamitonggyung-tang for three menstrual cycles. We estimated the effects by Visual Analog Scale (VAS), Menstrual Distress Questionnaire (MDQ) and checked amount of the analgesics taken during menstrual phase. Results: After treatment, the mean of VAS, MDQ Score and amount of the analgesics taken were decreased. Conclusions: This case shows that Gamitonggyung-tang is effective in treating primary dysmenorrhea patients.

• 대한조현병학회지
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• 제24권1호
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• pp.36-43
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• 2021

Objectives: Despite the high discontinuation rate of clozapine in refractory schizophrenia, there is limited evidence regarding the suggested treatment after clozapine discontinuation. Methods: The medical records of 37 patients who discontinued clozapine were retrospectively reviewed. The prescription patterns of antipsychotics, mood stabilizers, and antidepressants were compared at three points before and after clozapine treatment and at the most recent visit. Results: After clozapine discontinuation, 75.6% of the subjects were receiving antipsychotic polypharmacy, and 32.4% were taking more than 3 antipsychotics. The frequently used antipsychotics were olanzapine (21.5%), quetiapine (21.5%), and paliperidone (12.7%). The rates of augmentation with mood stabilizers and antidepressants were 43.2% and 29.7%, respectively. Furthermore, valproate was the most commonly used mood stabilizer (87.5%). Conclusion: Antipsychotic polypharmacy and augmentation are inevitable in schizophrenia patients for whom clozapine has been discontinued. Further research is required to improve the outcomes of polypharmacy and augmentation in schizophrenia patients.

• 대한한방내과학회지
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• 제39권4호
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• pp.708-716
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• 2018

Objectives: The purpose of this study was to conduct a clinical analysis of gastrointestinal cancer patients treated with Korean medical therapy. Methods: We analyzed a retrospective review of 226 gastrointestinal cancer patients treated in the cancer center of a Korean medicine hospital from February 2012 to August 2017. The patients' general characteristics, including the tumor, origin, stage of cancer, type of treatment, and chief complaint, were investigated before and after the treatment. Results: The largest proportion of tumor origins in total patients and inpatients was gastric cancer. Overall, 54.9% of the patients' tumors were stage IV. In total, 65.9% of patients visited the Oriental hospital for combination treatment with conventional medicine. The patients' chief complaints were abdominal discomfort, general weakness, and general cancer-related pain. Conclusions: This study presented the characteristics of patients with gastrointestinal cancer treated with Oriental medicine. Further advanced studies of Oriental medical cancer treatments are needed, based on the findings of this study.