• Asian-Australasian Journal of Animal Sciences
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• v.15 no.9
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• pp.1319-1325
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• 2002

Two experiments were conducted to evaluate the effect of early feed restriction on growth, feed conversion ratio (FCR) and mortality in unsexed broiler chickens. In Experiment 1, 350 one-day-old broiler chickens were divided into 7 groups. Each treatment group was represented by five replicates of ten broilers each. One group was fed ad libitum as the control group and the other six groups were fed 25% ad libitum (25% multiplied by amount of feed intake of ad libitum chickens at the previous day) for 4 or 6 days, 50% ad libitum for 4 or 6 days, and 75% ad libitum for 4 or 6 days. In experiment 2, 500 broiler chickens were divided into 10 groups. Each treatment group was represented by five replicates of ten broilers each. One group was fed ad libitum as the control group. Three ages of feed restriction initial timing (2, 4 or 6 days of age) and three types of feed restriction (physical restriction, meal feeding and diet dilution) were used ($3{\times}3$) in both experiments. They were feed-restricted for 6 days. Results showed that restricted broilers exhibited compensatory growth in both experiments except for diet dilution groups. In both experiments, FCR of restricted broilers was higher, whereas feed intake of them was lower during restriction period. FCR of restricted broilers was lower upon refeeding. Mortality was inconsistently affected by early feed restriction. Leg abnormality was lower in restricted broilers in both experiments. Level of feed restriction significantly influenced body weight, FCR and feed intake of restricted broilers (p<0.05), but duration of feed restriction had no effect. Type of restriction significantly affected body weight, feed intake and FCR (p<0.05). It appeared that to achieve the best result (complete compensatory growth and better FCR), broilers should be restricted at 25% ad libitum for 6 days (Experiment 1). Meal feeding started at 2 days of age would show the best performance (Experiment 2).

• Asian-Australasian Journal of Animal Sciences
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• v.6 no.3
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• pp.401-410
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• 1993

Day-old male and female broilers obtained from commercial strain (Hubbard) were used in this study. At 7 days of age, all chicks were weighed individually (female 0.11 kg and male 0.12 kg in average) and divided into 5 group of 45 birds each group with no replicate in each treatment group as follows: 1. fed ad libitum; 2. fed 75% ad libitum; 3. fed 65% ad libitum; 4. fed 55% ad libitum; 5. fed 45% ad libitum. Chicks were restricted for 10 days (d 7 through 17) of a 56-day trial. Chicks were fed a commercial starter diet (crude protein (CP) 23.8% and metabolizable energy (ME) 3,070 kcal/kg) for 21 days, and commercial finisher diet (CP 20% and ME 3,160 kcal/kg) from 22 to 56 days of age. When chicks were feed-restricted at an early age, compensatory growth did not immediately occur following refeeding. Body weights of restricted chicks were not equal to the ad libitum chicks before 49 days of age. At 56 dyas of age, body weights of restricted chicks were heavier (p<0.01). Abdominal fat values of female chicks fed ad libitum was not significantly different from those fed 45% to 75% ad libitum. Carcass fat values of restricted female chicks were lower than those of control chicks when female chicks were fed either 55% or 45% ad libitum. Furthermore, feed efficiencies of restricted chicks were better. The response of chicks to early feed restriction might depend on the degree of feed restriction, and sex. Factors contributing carcass fat included energy loss, fat protein ratio of carcass, fatty acid synthesis in the liver and triglyceride content of the liver. The heavier body weights in the restricted chicks might be correlated with the lower growth rate during period of feed restriction.

• Korean Journal of Social Welfare Studies
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• v.45 no.2
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• pp.173-202
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• 2014

This qualitative study is designed to explore parents' experiences with their children handicapped with restricted growth. The parents' unique reality and its essential meanings are elicited through in-depth interviews enabling to reflect the insider's perspective. "From the child unable to grow to the child able to grow" is identified as the main theme penetrating through the participants'parenting experiences unique to their reality. Embracing the shock and the disappointment related to their children 'unable to grow', they thrive to make their children able to grow. However, they eventually accept their children's handicap, in spite of never doing it easily, by getting confronted with the limits of making their children grow in stature, and the social stigma and the difficulty their children experience. Therefore, they get to take alternative perspectives not focusing on their children's stature unable to grow but on psycho-social growth able to grow. Social welfare plans to support the handicapped with restricted growth and their parents are suggested.

• Asian-Australasian Journal of Animal Sciences
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• v.19 no.11
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• pp.1643-1648
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• 2006

To investigate the effects of feeding restricted on growth, carcass characteristics and plasma profiles in an attempt for optimum responses, a total of 108 cross-bred finishing barrows [(Landrace${\times}$Yorkshire)${\times}$Duroc]weighing an average of $46.88{\pm}0.52kg$ were assigned in a randomized complete block (RCB) design to one of four treatments with three replicates and nine pigs per pen. Feeding regimens were, 1) ad libitum from 50 kg to market weight (Ad 3/3), 2) restricted feeding from 90 kg to market weight (Ad 2/3), 3) restricted feeding from 70 kg to market weight (Ad 1/3), and 4) restricted feeding from 50 kg to market weight (Ad 0/3). During the experimental period, average daily feed intake (ADFI) was decreased from 2.53 kg (AD 3/3) to 2.09 kg (AD 0/3) with increasing restricted feeding duration of (p<0.05). Average daily gain (ADG) of AD 3/3 (0.79 kg) was significantly higher (p<0.05) than those of AD 1/3 (0.74 kg) or AD 0/3 (0.72 kg). Feed efficiency was not influenced by restriction regimens. Blood IGF-I concentrations were increased from 74.14 to 134.25 (167.36-115.66) ng/ml as body weight increased. Blood leptin concentrations were affected by feed intake level and coincided with blood IGF-I concentrations. Most of carcass characteristics were not significantly affected by restricted feeding, however cooking losses in AD 1/3 and Ad 0/3 treatment diet were higher than those in Ad 3/3 and Ad 2/3. In addition, there was a trend that backfat thickness was lowered in proportional to decreasing feed intake (p>0.05). In conclusion, restricted feeding improved feed efficiency after 50 kg body weight without deteriorating the pork quality of barrows.

• Asian-Australasian Journal of Animal Sciences
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• v.22 no.12
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• pp.1633-1639
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• 2009

This study investigated the effect of maternal undernutrition during late pregnancy on the growth and development of ovine fetal visceral organs. One hundred Mongolian ewes were mated at a synchronized oestrus and divided into three groups and offered 0.175 MJ ME $kgw^{-0.75}\;d^{-1}$ (Restricted Group1; RG1), 0.33 MJ ME $kgw^{-0.75}\;d^{-1}$ (Restricted Group2; RG2) and ad libitum access to feed (Control Group; CG) during late pregnancy (90 days). Selected animals in each group were slaughtered immediately at d 90 of pregnancy and after parturition (neonatal lambs), and major visceral organs were removed and weighed separately. The results indicated that the weights of lung (p<0.01), spleen (p<0.01), heart (p<0.05), liver (p<0.05) and abomasum (p<0.01) in RG1 were significantly lighter than those of CG. For RG2, only the weights of the lung (p<0.05) and spleen (p<0.01) were significantly lighter than those of CG; when expressed as a percentage of body weight, significance was retained in the spleen (p<0.01) for both restricted groups, but the percentage of brain in RG1 was significantly higher than that in CG (p<0.01). For lung and spleen, the amount of DNA was significantly lower (p<0.01) in both groups of restricted neonatal lambs compared to CG; however, there was a significant difference only between RG1 and CG for protein: DNA ratio (p<0.01). The DNA content of kidney, abomasum and jejunum were decreased (p<0.05) in RG1 neonatal lambs, but protein: DNA ratio in the liver was decreased compared with that of CG (p<0.05). The plane of maternal undernutrition during late pregnancy had a significant effect on the growth and development of fetal visceral organs, which altered ontogeny of fetal organ growth and development. These perturbations in fetal visceral development may have significant implications on postnatal growth and adult health.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.5
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• pp.655-658
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• 2004

Heat stress is known to affect physiological systems in goats. This study investigated changes in nutrient digestibility, behavior and growth hormone secretion among goats in a hot environment (H; 35${\pm}$ 1.2$^{\circ}C$, [RH] 80${\pm}$7.2%, 13 d), and in a thermoneutral environment (T; 20${\pm}$0.6$^{\circ}C$, [RH] 80${\pm}$3.4%, 20 d), and accompanied by the same restricted diet as provided in the hot environment. The following results were obtained: rectal temperature and water intake were higher in the H treatment than in the T treatment or TR treatment, while hay consumption was lower. CP, NDF and ADF digestibility was highest in H treatment. Time spent eating in the H treatment was also the highest, followed in order by T treatment and TR treatment. Ruminating time was lower in H treatment than in T treatment or TR treatment, and reposing time was highest in the TR treatment. Growth hormone concentrations in T increased 4.5 h after feeding. In H, growth hormone concentrations increased 0.5 h after feeding. However, growth hormone concentrations were not changed following TR feeding. In conclusion, heat exposure in goats decreased feed intake, but increased digestibility. However, when goats in a thermoneutral environment received the same restricted feeding as they received in the hot environment, digestibility increased. Between the H treatment and TR treatment, the changes in digestibility were accomplished by coordinate changes in hormone secretion in order to maintain body homeostasis. To maintain energy balance under a hot temperature or a restricted feeding condition, goats may control their metabolism by changing growth hormone release.

• Asian-Australasian Journal of Animal Sciences
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• v.18 no.8
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• pp.1075-1079
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• 2005

The main objective of this study is to examine genetic changes in growth rate and carcass composition traits in group housed, ad libitum fed pigs, from lines of Large White divergently selected over four years for high and low post-weaning daily gain on a fixed but restricted ration. Genetic parameters for production and carcass traits were also estimated by using average information-restricted maximum likelihood applied to a multivariate individual animal model. All analyses were carried out on 1,728 records of group housed ad libitum fed pigs, and include a full pedigree of 5,324 animals. Estimates of heritability (standard errors in parentheses) were 0.11 (0.04) for lifetime daily liveweight gain (LDG), 0.13 (0.04) for daily carcass weight gain (CDG) and 0.28 (0.06) for carcass backfat (CFT). Genetic correlations between LDG and CDG were highly positive and between LDG and CFT negative, suggesting that selection for lifetime daily gain under commercial conditions of group housing with ad libitum feeding would result in favourable improvement in carcass traits. CFT showed negative genetic correlations with CDG. Correlated genetic responses evaluated as estimated breeding values (EBVs) were obtained from a multivariate animal model-best linear unbiased prediction analysis. After four years of divergent selection for 6 week post-weaning growth rate on restricted feeding, pigs performance tested on ad libitum feeding in groups exhibited changes in EBVs of 6.77 and -9.93 (g/d) for LDG, 4.25 and -7.08 (g/d) for CDG, and -1.42 and 1.55 (mm) for CFT, in the high and low lines, respectively. It is concluded that selection for growth rate on restricted feeding would significantly improve genetic performance and carcass composition of their descendants when group housed and ad libitum fed as is a common commercial practice.

• Molecules and Cells
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• v.37 no.6
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• pp.480-486
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• 2014

Growth restriction by antibiotics is a common feature that pathogenic bacteria must overcome for survival. The struggle of bacteria to escape from growth restriction eventually results in development of antibiotic-resistance through the expression of a set of genes. Here we found that some physiologically important transcriptional regulators of Pseudomonas aeruginosa including QscR, a quorum sensing (QS) receptor, SoxR, a superoxide sensor-regulator, and AntR, a regulator of anthranilate-related secondary metabolism, are activated by various growth-restricted conditions. We generated the growth-restricted conditions by various methods, such as overexpression of PA2537 and treatment with antibiotics or disinfectants. The overexpression of PA2537, encoding an acyltransferase homologue, tightly restricted the growth of P. aeruginosa and significantly activated QscR during the growth restriction. Similarly, treatments with gentamycin, tetracycline, and ethanol also activated QscR near their minimal inhibitory concentrations (MICs). Some non-QS regulators, such as AntR and SoxR, were also activated near the MICs in the same conditions. However, LasR and PqsR, other QS receptors of P. aeruginosa, were not activated, suggesting that only a specific set of transcriptional regulators is activated by growth restriction. Since paraquat, a superoxide generator, significantly activated QscR and AntR, we suggest that the oxidative stress generated by growth restriction may be partly involved in this phenomenon.

• Fisheries and Aquatic Sciences
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• v.15 no.4
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• pp.305-311
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• 2012

We investigated compensatory growth of Nile Tilapia Oreochromis niloticus in structural size and live weight in response to different deprivation periods and refeeding. Four treatments were assigned randomly to fish in 12 glass tanks, with each treatment performed in triplicate. The control group was fed to satiation three times a day throughout the experiment. The other three treatment groups were starved for 1 week (S1), 2 weeks (S2), or 4 weeks (S4) and then fed until the end of the experiment. After the experiment, no significant differences were observed among S1, S2, and the control group in average weight or length, whereas the weight and length of S4 were significantly reduced. Relative condition factors of the three starved groups decreased significantly until the end of the restricted period but recovered rapidly after refeeding. The specific growth rate in weight ($SGR_W$) of the three restricted groups recovered quickly upon refeeding and were significantly higher than the control group, but these differences disappeared gradually until the end of the experiment. No significant difference in specific growth rate in length ($SGR_L$) was noted between the control group and the three restricted groups after refeeding. All three groups showed hyperphagia for a short period upon refeeding, and no statistical differences were observed in feeding efficiency among the four groups.

• Asian-Australasian Journal of Animal Sciences
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• v.24 no.6
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• pp.791-799
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• 2011

This study examined the effect of restricting feed intake and the subsequent compensatory growth in Guzera females. Eighteen animals with an initial age of 21 months and a mean weight of 268.17 kg were placed in three groups according to the alimentary regime: feed ad libitum; feed restricted to 20% dry matter; and feed restricted to 40% dry matter. In the restricted feed phase, the dry mater intake decreased as the restriction levels increased, influencing the reduction in intake of other nutrients. In the realimentation phase, the 40% restricted feed group ingested more dry matter (% BW) and crude protein ($weight^{0.75}$) than the group fed ad libitum (p<0.001). The serum nutrient concentrations were inversely proportional (p<0.001) to the restriction level, and there was no difference (p>0.001) in the realimentation phase. In the restricted feed phase, the final live weight decreased (p<0.05) as the restriction level increased. For the daily mean weight gain in the control group, there was no difference (p>0.05) compared to the animals with 20% feed restriction, but this was higher than in the group with 40% feed restriction. In the re-alimentation phase, the group with 40% feed restriction achieved higher weight gain rates, which was different from the control and 20% restriction groups. In both phases, the animals in the group with 40% feed restriction presented better feed conversion which was different (p<0.05) from the control group. In the feed restriction phase, it was observed that the intake of N, nitrogen excreted in feces and urine, nitrogen balance and nitrogen retention decreased (p<0.05) with the restriction level. None of the variables were influenced in the re-alimentation phase. These results show that feed restriction by 40% can be adopted as a nutritional management practice.