• Nuclear Medicine and Molecular Imaging
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• 제42권sup1호
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• pp.91-100
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• 2008

Ovarian cancer is often fatal since it is difficult to diagnose early and recurrence is quite frequent despite successful implementation of cytoreductive surgery and chemotherapy, thus exact diagnosis and early detection of recurrence are crucial to patient management. For pre-treatment staging, FDG PET could be helpful in a limited patient group possessing high risks of ovarian cancer. Besides, FDG PET could be recommended to patients with a high suspicion of recurrence i.e. rise of CA-125, especially in cases of conventional diagnostic imaging modalities presenting no evidence of disease because FDG PET provides critical information for treatment planning such as recurrence site or pattern. In order to expand the use of FDG PET to general population at staging or routine surveillance of ovarian cancer, more investigation is needed. The usefulness of FDG PET in evaluating treatment response and prognosis of ovarian cancer has not yet been determined, but it has been reported that FDG PET could evaluate treatment response early and show a close relationship with overall survival. PET/CT has been actively adopted in management of ovarian cancer. Not only in detecting tumor recurrence and evaluating treatment response but also in pre-treatment staging, FDG PET/CT is expected to playa role due to available anatomical information.

• 한국방사선학회논문지
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• 제11권4호
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• pp.177-181
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• 2017

방사선 생물학적 효과(Radio biological effectiveness, RBE)를 선량에 대부분 의존하는 X선과 달리 탄소빔의 경우 LET의 변화량은 반드시 고려되어야할 사항이다. 이는 X선 과는 극히 대조적인 선량 분포도를 갖고 있기 때문이며 LET의 변화량이 중요한 이유가 된다. 따라서 기존의 LQ 모델이나 회복생존모델의 경우 이러한 점이 감안되지 않아 탄소빔의 분할 조사 시 문제점을 보이며 오류를 보이고 있다. 본 연구에서는 약 $75keV/{\mu}m$의 고LET 탄소빔 분할 조사 시 Potentially Lethal Damage Repair (PLDR)의 발생양을 확인하고 약 $13keV/{\mu}m$ 저LET 조사와 비교하여 현저히 감소하였음을 확인하였다. PLDR의 감소에 따라 생존율 또한 감소하였다. 따라서 탄소빔의 생물리학적 모델 개발에 LET의 변화량은 반드시 고려되어져야 할 것으로 보인다.

• 농촌계획
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• 제23권1호
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• pp.147-156
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• 2017

This study suggests a plan to expand the rural experience program linked to natural disaster through the case analysis of the village of Garisan-ri, Inje-gun, Gangwon-do, Republic of Korea. This will help to establish the necessary improving and policies for Re-leap of rural villages in disaster areas and activation of rural experience villages. The local residents have created flood recovery stories, disaster response content, and disaster prevention camp sites, all of which have been hit by serious disaster damage. It has also contributed to the revitalization of the village by providing various experience programs such as disaster response training, crossing rapids, and evacuation experience. This is a way to get rid of the negative perception of disaster and utilize it. The conversion of idea through disaster experience content contributed to the activation of the area. By linking the disaster experience contents to the rural experience program in the future, it can be helpful to avoid the duplication of contents and limit the similar operation method, which is an existing problem of rural experience villages.

• Journal of Preventive Medicine and Public Health
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• 제42권2호
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• pp.73-81
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• 2009

Objectives : This study presents a scientific basis for the establishment of an environmental health contingency plan for dealing with accidental coastal oil spills and suggests some strategies for use in an environmental health emergency. Methods : We reviewed the existing literature, and analyzed the various fundamental factors involved in response strategies for oil spill. Our analysis included data derived from Hebei Spirit oil spill and used air dispersion modeling. Results : Spill amounts of more than 1,000 kl can affect the health of residents along the coast, especially those who belong to vulnerable groups. Almost 30% of South Korean population lives in the vicinity of the coast. The area that is at the highest risk for a spill and that has the greatest number of people at risk is the stretch of coastline from Busan to Tongyeong. The most prevalent types of oil spilt in Korean waters have been crude oil and bunker-C oil, both of which have relatively high specific gravity and contain volatile organic compounds, polycyclic aromatic hydrocarbons, and metals. In the case of a spill of more than 1,000 kl, it may be necessary to evacuate vulnerable and sensitive groups. Conclusions : The government should establish environmental health planning that considers the spill amount, the types of oil, and the distance between the spot of the accident and the coast, and should assemble a response team that includes environmental health specialists to prepare for the future oil spill.

• 농촌계획
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• 제28권4호
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• pp.55-67
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• 2022

In this study, the village development promotion system was reorganized for Gimhae-si, and improvement plans and post-operation management plans were prepared through expert surveys. Through the Village Development Project, the landscape and environment of the village were improved, and the village and residents were positively changed. The Village Development Project laid the foundation for regional revitalization, giving the next generation hope for the sustainable development of the village. While maintaining the framework of the existing Rural Development Projects guidelines through case analysis of other regions, we operate educational programs for each stage by reflecting regional characteristics, and utilize and communicate with intermediate support organizations, systematically operate, and actively intervene by Eup·Myeon administration. In addition, as a follow-up management program, various follow-up management programs were being operated, such as support for capacity building such as consulting, as well as facility maintenance and support for village managers. As a result of the expert survey to review the adequacy of the improvement plan, the improvement plan derived from the overall average of 4.28 points and the standard deviation of 0 to 0.94 points for the process is judged to be appropriate. In particular, the item of 'self-reliance stage follow-up management' was very important as all experts responded with 5 points. By establishing the village development performance goals, we tried to check whether the qualitative/quantitative goals were achieved by year, and to secure quantified status data in response to changes such as resetting performance goals or adding new performance indicators. In this study, in order to improve the capacity to achieve regional development in response to the rural agreement, we prepared our own sustainable village development promotion system, governance establishment, and follow-up management plan. In addition, it is expected to be used as a reference material for the selection of new districts and the follow-up management of completed districts by establishing the village development goals.

• 국제초고층학회논문집
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• 제1권1호
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• pp.37-51
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• 2012

New generation of tall and complex buildings systems are now introduced that are reflective of the latest development in materials, design, sustainability, construction, and IT technologies. While the complexity in design is being overcome by the availability and advances in structural analysis tools and readily advanced software, the design of these buildings are still reliant on minimum code requirements that yet to be validated in full scale. The involvement of the author in the design and construction planning of Burj Khalifa since its inception until its completion prompted the author to conceptually develop an extensive survey and real-time structural health monitoring program to validate all the fundamental assumptions mad for the design and construction planning of the tower. The Burj Khalifa Project is the tallest structure ever built by man; the tower is 828 meters tall and comprises of 162 floors above grade and 3 basement levels. Early integration of aerodynamic shaping and wind engineering played a major role in the architectural massing and design of this multi-use tower, where mitigating and taming the dynamic wind effects was one of the most important design criteria established at the onset of the project design. Understanding the structural and foundation system behaviors of the tower are the key fundamental drivers for the development and execution of a state-of-the-art survey and structural health monitoring (SHM) programs. Therefore, the focus of this paper is to discuss the execution of the survey and real-time structural health monitoring programs to confirm the structural behavioral response of the tower during construction stage and during its service life; the monitoring programs included 1) monitoring the tower's foundation system, 2) monitoring the foundation settlement, 3) measuring the strains of the tower vertical elements, 4) measuring the wall and column vertical shortening due to elastic, shrinkage and creep effects, 5) measuring the lateral displacement of the tower under its own gravity loads (including asymmetrical effects) resulting from immediate elastic and long term creep effects, 6) measuring the building lateral movements and dynamic characteristic in real time during construction, 7) measuring the building displacements, accelerations, dynamic characteristics, and structural behavior in real time under building permanent conditions, 8) and monitoring the Pinnacle dynamic behavior and fatigue characteristics. This extensive SHM program has resulted in extensive insight into the structural response of the tower, allowed control the construction process, allowed for the evaluation of the structural response in effective and immediate manner and it allowed for immediate correlation between the measured and the predicted behavior. The survey and SHM programs developed for Burj Khalifa will with no doubt pioneer the use of new survey techniques and the execution of new SHM program concepts as part of the fundamental design of building structures. Moreover, this survey and SHM programs will be benchmarked as a model for the development of future generation of SHM programs for all critical and essential facilities, however, but with much improved devices and technologies, which are now being considered by the author for another tall and complex building development, that is presently under construction.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제26권4호
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• pp.273-278
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• 2015

Objectives : We retrospectively investigated the efficacy and tolerability of risperidone monotherapy in subjects with autism spectrum disorder (ASD). In addition, we did mixed effect model analysis of the effects of risperidone in patients with ASDs naturalistically treated in a routine clinical setting to determine whether the clinical effects were maintained and the side effects were tolerable. Methods : This retrospective study assessed children and adolescents with ASD, who were on risperidone monotherapy from July 2010 to July 2011 at the Child and Adolescent ASD Clinic at Seoul National Hospital. Outcome measures included the Clinical Global Impression-Severity of Illness (CGI-S) and the CGI-Improvement (CGI-I) scales along with other clinical indices: dosage, target symptoms, and side effects. Results : The mean dose of risperidone in 47 children and adolescents with ASD (40 males, 7 females; age range 5-19 years) who were on risperidone monotherapy was $1.6{\pm}0.8mg/day$, and the mean duration of the treatment period was $20.2{\pm}17.3months$. Aggressive behavior, stereotypic behavior, irritability, and self-injurious behavior were the most frequent target symptoms of risperidone. The most common side effects were weight gain followed by somnolence and extrapyramidal symptoms. In a mixed effects model analysis of CGI-I scores, the mean CGI-I score at the 1 month follow-up was significantly different from the mean CGI-I score of the 3-month follow-up (p=.046), and the CGI-I scores were equally maintained over 3 to 48 months [F(6, 28.9)=4.393, p=.003]. Of the 47 patients, 33 patients (70.2%) were identified as the response group, showing an end point CGI-I rating of 3 or under and having continued risperidone treatment for at least 6 months. The baseline CGI-S score showed significant association with clinical response to risperidone (p=.005), the mean baseline CGI-S was higher in the response group compared to the non-response group. Conclusion : In this study, clinical improvement of risperidone stabilized around 3 months and was equally maintained up to 48 months with tolerable side effects, supporting maintenance of risperidone treatment in children and adolescents with ASDs.

• 환경영향평가
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• 제33권3호
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• pp.116-130
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• 2024

역사적으로 인류는 풍부한 자원과 식수를 제공할 수 있는 수변 공간에 정착하였고, 산업화가 진행되며 도시의 수변 공간은 농업 및 공업 용수의 제공, 교통 수단, 문물의 교역, 산업의 발달 등 도시 발전에 중요한 역할을 담당하였다. 산업 구조의 변화에 따라 지난 수십년간 도시의 수변 공간은 산업과 항만 위주의 기능에서 공공공간의 기능으로 전환되고 있으며, 도시재생의 관점에서 전세계적으로 지속가능한 수변공간 개발에 대한 연구와 설계가 활성화되고 있다. 하지만 수변 공간 인근 지역은 해수면 상승 및 폭우 등 기후변화 인한 자연 재해의 직접적인 영향을 받는 지리적 취약성을 지니고 있기 때문에 시민들의 안전과 공공성 확보를 위한 체계적인 관리 계획 수립이 필수적이다. 미국 뉴욕시는 1990년대부터 도시 단위의 수변공간 관리계획을 수립하고 수변공간의 공공성과 안전성, 형평성을 확보해나가고 있다. 반면, 국내에서는 도시 단위의 수변관리계획에 대한 연구가 부족한 실정이다. 이에 본 연구에서는 뉴욕시 수변종합계획이 발전되어 온 과정과 주요 정책들에 대해 고찰함으로써 국내 수변공간계획에 대한 시사점과 정책적 개선방안을 모색하고자 하였다.

• 대한공업교육학회지
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• 제38권2호
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• pp.218-239
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• 2013

본 연구는 남자대학생의 군 의무복무계획과 진로장벽인식의 정도를 파악하고, 군 의무복무계획 수준에 따른 진로장벽인식과 진로준비행동의 차이를 살펴보는데 그 목적이 있다. 이를 위해 대전 충남지역 남자 대학생 284명을 대상으로 군 의무복무계획, 진로장벽인식, 진로준비행동 척도를 사용하여 설문을 실시하고 군 의무복무계획과 진로장벽인식 정도, 군 의무복무계획 수준에 따른 진로장벽인식과 진로준비행동의 차이를 알아보기 위해 기술통계, 상관분석, t검정을 실시하였다. 연구 결과 첫째, 남자대학생의 79.2%가 군 의무복무계획을 가지고 있는 것으로 나타났다. 그러나 각 하위요인을 살펴보면 전체적인 군 의무복무계획의 수준은 높은 편이지만 계획을 세우기 위한 실제적 행동적 노력을 행하는 남자대학생들은 비교적 적다는 것을 알 수 있다. 또한 남자대학생의 73.9%가 진로에 있어 군 의무복무를 장벽으로 인식하고 있으며, '매우 그렇다'고 응답한 비율이 최대 집단(16.9%)으로 나타났다. 또한, 각 문항별 응답분포를 통해 군 의무복무 시기의 문제, 시간에 대한 기회비용과 남들보다 뒤쳐질 수 있다는 어려움을 높게 인식한다는 것을 알 수 있다. 둘째, 군 의무복무계획 상 하위 집단 간 진로장벽인식의 차이는 유의미하게 나타나지 않았으나 하위요인인 중요성의 경우 상 하위 집단 간 진로장벽인식의 유의미한 차이가 나타났다. 다시 말해서, 남자대학생에게 군 의무복무라는 장벽은 군 의무복무계획 수준과 상관없이 자신들의 진로과정에 있어 방해요소로 인식되고 있으며, 군 의무복무계획의 중요성을 높게 인식하고 있는 집단이 그렇지 않은 집단보다 군 의무복무를 더 큰 장벽으로 인식하고 있음을 보여준다. 셋째, 군 의무복무계획의 상 하위 집단 간 진로준비행동의 차이는 유의미하게 나타났다. 즉, 군 의무복무계획 수준이 높은 학생들이 상대적으로 높은 진로준비행동을 보였다는 것은 군 의무복무계획의 필요성을 시사해주는 것으로 볼 수 있다. 본 연구를 통해 남자대학생과 진로상담자에게 군 의무복무계획의 필요성을 제시하였다. 또한 군 의무복무 전 대상자를 대상으로 한 선행연구들을 거의 찾아볼 수 없는 실정에서 한국적 진로발달과정의 독특한 특성인 '군 의무복무'에 관한 경험적 자료를 축적하는데 의의가 있다.

• 자원ㆍ환경경제연구
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• 제16권1호
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• pp.99-127
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• 2007

시간대별 차등요금제(Time-based Pricing)를 포함하여 전력시장에 존재하는 다양한 수요반응(Demand Response) 제도를 개발하고 이를 활성화하기 위한 정책적 수단들이 해외 선진국 전력시장을 중심으로 활발하게 진행되고 있다. 미국의 경우, 2005년 발효된 에너지법에 의하여 이러한 수요반응의 활성화가 준비되고 있으며, 이에 따라 미국의 각 주에서는 신뢰할 수 있고 활용 가능한 수요반응 서비스를 소비자에게 제공하기 위한 다각적인 노력을 시행하고 있다. 즉, 실시간 요금제도(Real-Time Pricing)와 지역별 요금제도(Locational Pricing)의 도입을 통해 시간과 공간에 따른 차등 요금제를 채택하고 있으며, 다양한 인센티브기반 수요반응(Incentive-based DR) 프로그램에 기초하여 기존의 공급자 위주의 수요관리 프로그램들이 시장 친화적 프로그램인 수요반응 프로그램으로 빠르게 변화하고 있다. 우리나라 전력시장에서도 1970년대 이후로 현재까지 다양한 수요관리사업들이 시행되어 오고 있으나, 해외 전력시장의 사례와 같이, 소비자 중심적이고 시장 친화적인 수요자원 활용으로의 전환이 체계적으로 이루어지지 않고 있는 실정이다. 따라서 본 논문에서는 수요반응자원을 전력시장에 도입했을 때 발생할 수 있는 다양한 이익(전력시장 효율 증진 효과, 공급비용 회피 효과, 현물시장 가격감소 효과 등)에 대한 정량적이고 이론적인 분석을 수행하였으며, 이를 통해 수요반응제도 도입의 사회경제적 이익을 계량화하기 위한 방법을 제시하였다.