• Title/Summary/Keyword: Respiratory Disease

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Analysis of Respiratory and Cardiovascular Diseases according to PM Concentration in the Incheon Area (인천시 자치구별 미세먼지 농도에 따른 호흡기 및 심혈관계 외래환자 수 상관분석)

  • Lee, Seungwoon;Jung, Seungkwon
    • Journal of Environmental Health Sciences
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    • v.46 no.3
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    • pp.276-284
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    • 2020
  • Objectives: This study was conducted to identify the effects of PM10 and PM2.5 on hospital visits in the Incheon area over the period of 2016-2018. Methods: We applied correlation analysis and Poisson regression to perform the analysis using cardiovascular disease and respiratory disease data from the National Health Insurance Service and the daily average PM10 and PM2.5 from the Korea Environment Corporation adjusting for time lag. Results: When the daily average PM10 concentration increased by 10 ㎍/㎥, the number of cardiovascular disease patients were 1.002 times higher (95% CI [Confidence Interval]; 1.000-1004) in Ganghwa County. As the daily average PM2.5 concentration increased by 10 ㎍/㎥, the number of cardiovascular disease patients were 1.012 times higher (95% CI; 1.008-1.016) in Ganghwa County. As the daily average PM10 concentration increased by 10 ㎍/㎥, the respiratory disease patients were 1.003 times (95% CI; 1.002-1.004) higher in Gyeyang and Michuhol Counties. As the PM2.5 concentration increased by 10 ㎍/㎥, the respiratory disease patients were 1.003 times higher (95% CI; 1.002-1.005) in Bupyeong County. Conclusions: In some parts of the Incheon area there was a correlation between the number of patients with respiratory and cardiovascular conditions and the concentration of PM10 and PM2.5.

The Effect of Types of Respiratory Exercise on Respiratory Muscle Activity and Health-Related Quality of Life of Patients with Severe Chronic Obstructive Pulmonary Disease

  • Kang, Jeong-Il;Jeong, Dae-Keun;Choi, Hyun
    • The Journal of Korean Physical Therapy
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    • v.28 no.1
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    • pp.46-51
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    • 2016
  • Purpose: This study intended to classify voluntary respiratory exercise and exercise using breathing training equipment to suggest proper respiratory exercise to relieve symptoms of patients with severe chronic obstructive pulmonary disease. Methods: Sixteen subjects were randomly selected for experimental group I, which performed feedback breathing exercise and 15 subjects were randomly selected for experimental group II, which performed a complex breathing exercise. The mediation program was performed 30 minutes a session, once a day, three times a week, for five weeks. This study analyzed before and after results within groups and between groups through measurement of respiratory muscle activity and health-related quality of life. Results: Activity of sternocleidomastoid muscle and scalene muscle increased meaningfully within experimental group I and activity of diaphragm increased significantly within experimental group II (p<0.05) and there was a meaningful difference in health-related quality of life within experimental group II (p<0.05). Significant differences in change of activity of respiratory muscle and health-related quality of life were observed between groups (p<0.05). Conclusion: This study showed conflicting results between activity of agonist and synergist in patients with severe chronic obstructive pulmonary disease according to types of respiratory exercise and that complex respiratory exercise is more effective in health-related quality of life. Therefore, it found that the more severity increase, the more self-respiratory technique is an effective program. Diversified approach methods will be needed to improve respiratory function and quality of life for patients, and continuous clinical studies will be needed in the future.

Studies on the electrophoretic analysis of serum protein in Korean native calves (한우(韓牛) 송아지의 혈청단백분획(血淸蛋白分劃)에 관(關)한 연구(硏究))

  • Kim, Heung-seop;Lee, Joo-mook;Kwon, Oh-deog;Park, Jin-ho;Park, Sang-youel;Lee, Sung-ok
    • Korean Journal of Veterinary Research
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    • v.37 no.2
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    • pp.451-456
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    • 1997
  • 120 heads of korean native calves were examined of serum protein by using cellulose acetate electrophoresis. During 20 days since the calves were purchased, serum protein, fibrinogen values and plasma : fibrinogen ratio were examined in the calves with respiratory and diarrheal disease. The result obtained in this investigation were as follows : 1. Among the 120 heads of calves that were purchased from market, 14 heads(22%) of calves were occurred respiratory disease, and 12 heads(20%) of calves are occurred diarrhea. Occurrence of respiratory disease was 14.5(4~20) days in average and diarrhea was 9.6(2-15) days after they had been purchased. 2. Serum protein fraction were analyzed by cellulose acetate electrophoresis. ${\beta}-globulin$, A/G ratio and ${\beta}_2-globulin$ values were decreased in the calves with respiratory disease. Especially, ${\beta}_2-globulin$ were significantly decreased. In calves with diarrhea, there was no change in ${\beta}-globulin$ values. ${\beta}_2-globulin$ values were higher than that of the normal and respiratory diseased calves. 3. ${\alpha}-globulin$ values were increased in both of calves with diarrhea and respiratory disease. This tendency was due to increase ${\alpha}_2-globulin$ values. 4. The $\gamma$-globulin value of calves with diarrhea was the lowest among the 3 groups. 5. The total protein values of normal calves were $7.0{\pm}1.1g/dl$ and that of respiratory and diarrheal diseased calves were $6.9{\pm}0.9g/dl$ and $6.6{\pm}0.8g/dl$, respectively. Total protein value of calves with diarrhea was lower than that of normal and respiratory diseased calves. Globulin value of calves with diarrhea was the lowest among them. The low value of total protein in diarrheal diseased calves was due to decrease globulin values. 6. The fibrinogen values of calves with respiratory disease ($643{\pm}189mg/dl$) were significantly higher than that of normal calves($533{\pm}135mg/dl$) and calves with diarrhea($572{\pm}188mg/dl$). The plasma : fib. ratio of respiratory diseased calves was $12.0{\pm}4.9$, normal calves was $13.8{\pm}3.5$ and diarrheal diseased calves was $12.8{\pm}4.6$. The ratio of the calves with respiratory disease was significantly decreased.

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Characteristics of Respiratory Disease Deaths from COVID-19 in One Region (일개 지역의 코로나19에서의 호흡기계 질환 사망 특성)

  • Hyeon-Gyeong Lee;Kyong-Jin Park
    • Journal of the Korean Society of Industry Convergence
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    • v.27 no.2_2
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    • pp.457-465
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    • 2024
  • This study used Korea's cause of death statistical data to identify the scale and characteristics of deaths from respiratory diseases in Jeollabuk-do over the past five years ('18~'22). The average number of deaths due to respiratory diseases in Jeollabuk-do over the past five years was approximately 11.5% of all deaths, and pneumonia accounted for 81.0% of deaths due to respiratory diseases. Deaths from respiratory diseases were highest among men, those in their 80s, those who were widowed, and those with elementary school education. The highest number of deaths by occupation were skilled agricultural, forestry and fishery workers, but when standardized by age, the highest number of deaths were among technicians and related workers. The main place of death due to respiratory diseases was found to be medical institutions. In order to reduce the occurrence and death of respiratory diseases, it is necessary to establish resident health promotion and disease management health policies that reflect regional characteristics.

Diagnosis of Pulmonary Tuberculosis and Nontuberculous Mycobacterial Lung Disease in Korea

  • Kwon, Yong Soo;Koh, Won-Jung
    • Tuberculosis and Respiratory Diseases
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    • v.77 no.1
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    • pp.1-5
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    • 2014
  • The recovery of nontuberculous mycobacteria (NTM) from respiratory specimens and the number of patients with NTM lung disease have been rapidly increasing in Korea. An early differential diagnosis of NTM lung disease from pulmonary tuberculosis (TB) is important, as the therapeutic regimen differs from that of pulmonary TB, and it is not necessary to track the contacts of patients with NTM lung disease. However, differentiating NTM lung disease from pulmonary TB remains difficult, because the clinical presentations of the two diseases are similar and a definite diagnosis of NTM lung disease based on sputum culture takes time. This review focuses on the changing epidemiology, clinical and radiographic manifestation, and laboratory diagnosis of pulmonary TB and NTM lung disease in Korea.

The Importance of Early Chronic Obstructive Pulmonary Disease: A Lecture from 2022 Asian Pacific Society of Respirology

  • Don D. Sin
    • Tuberculosis and Respiratory Diseases
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    • v.86 no.2
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    • pp.71-81
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    • 2023
  • Chronic obstructive pulmonary disease (COPD) affects close to 400 million people worldwide. COPD is characterized by significant airflow limitation on spirometry. Most patients with COPD are diagnosed in their fifth or sixth decades of life. However, the disease begins much earlier. By the time airflow limitation is detected on spirometry, patients with COPD have lost close to 50% of their small airways. Thus, identification of patients with early COPD, defined as persons with preserved spirometry, who demonstrate pathologic or functional hallmarks of COPD, is essential for disease modification and ultimately disease elimination. This paper provides an up-to-date overview of the current case definition of early COPD, its importance, the novel technologies required for its detection in young adults and future directions in therapeutics for treatment.

Diagnosis and Treatment of Nontuberculous Mycobacterial Lung Disease: Clinicians' Perspectives

  • Ryu, Yon Ju;Koh, Won-Jung;Daley, Charles L.
    • Tuberculosis and Respiratory Diseases
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    • v.79 no.2
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    • pp.74-84
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    • 2016
  • Nontuberculous mycobacteria (NTM) are emerging pathogens that affect both immunocompromised and immunocompetent patients. The incidence and prevalence of NTM lung disease are increasing worldwide and rapidly becoming a major public health problem. For the diagnosis of NTM lung disease, patients suspected to have NTM lung disease are required to meet all clinical and microbiologic criteria. The development of molecular methods allows the characterization of new species and NTM identification at a subspecies level. Even after the identification of NTM species from respiratory specimens, clinicians should consider the clinical significance of such findings. Besides the limited options, treatment is lengthy and varies by species, and therefore a challenge. Treatment may be complicated by potential toxicity with discouraging outcomes. The decision to start treatment for NTM lung disease is not easy and requires careful individualized analysis of risks and benefits. Clinicians should be alert to those unique aspects of NTM lung disease concerning diagnosis with advanced molecular methods and treatment with limited options. Current recommendations and recent advances for diagnosis and treatment of NTM lung disease are summarized in this article.

The Effects of Breathing Exercise on Respiratory Synergist Muscle Activity and SpO2 in Patients with Chronic Obstructive Pulmonary Disease

  • Jeong, Dae-Keun
    • The Journal of Korean Physical Therapy
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    • v.27 no.4
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    • pp.234-239
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    • 2015
  • Purpose: This study is not a fragmentary study on characteristics of respiratory synergist when breathing, however it was intended to determine the effect of currently available respiratory exercise and to provide basic clinical information through investigation of oxygen demand and respiratory synergist that mobilizes for respiration during application of respiratory exercise. Methods: Experimental group I was selected from second grade of severity classification of GOLD, which has the highest percentage among patients with COPD, and experimental group II was selected from third grade of severity classification as a clinical sampling. After respiration pursing up lips and diaphragm respiration exercise were mediated together for six weeks, activity of respiratory muscles and oxygen saturation were measured and analyzed. Results: In comparison of change of respiratory synergist and oxygen saturation, activity of respiratory synergist in sternocleidomastoid muscle and scalene muscle showed a meaningful decrease in experimental group I. And, in comparison of change of respiratory synergist and oxygen saturation, activity of respiratory synergist in rectus abdominis muscle showed a meaningful increase in experimental group II. In comparison of change of respiratory synergist and oxygen saturation, activity of respiratory synergist in sternocleidomastoid muscle, scalene muscle, and rectus abdominis muscle showed a meaningful difference between experimental groups. Conclusion: Respiratory synergists work mainly as agonist of chest and upper limbs. Therefore it is very important to lower mobilization of respiratory synergist when breathing. It is considered that a multilateral approach and continued clinical research for improvement of respiratory function for patients with COPD will be needed in the future.

Acute Eosinophilic Pneumonia

  • Sohn, Jang Won
    • Tuberculosis and Respiratory Diseases
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    • v.74 no.2
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    • pp.51-55
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    • 2013
  • Acute eosinophilic pneumonia is a severe and rapidly progressive lung disease that can cause fatal respiratory failure. Since this disease exhibits totally different clinical features to other eosinophilic lung diseases (ELD), it is not difficult to distinguish it among other ELDs. However, this can be similar to other diseases causing acute respiratory distress syndrome or severe community-acquired pneumonia, so the diagnosis can be delayed. The cause of this disease in the majority of patients is unknown, even though some cases may be caused by smoke, other patients inhaled dust or drugs. The diagnosis is established by bronchoalveolar lavage. Treatment with corticosteroids shows a rapid and dramatic positive response without recurrence.