• Journal of Digital Contents Society
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• v.14 no.1
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• pp.89-95
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• 2013

Many peer-to-peer (p2p) systems have been studied in distributed, ubiquitous computing environments. Distributed hash table (DHT)-based p2p systems can improve load-balancing even though locality utilization and user mobility are not guaranteed. We propose a mobile locality-based hierarchical p2p overlay network (MLH-Net) to address locality problems without any other services. MLH-Net utilizes mobility features in a mobile environment. MLH-Net is constructed as two layers, an upper layer formed with super-nodes and a lower layer formed with normal-nodes. The simulation results demonstrate that MLH-Net can decrease discovery routing hops by 13% compared with JXTA and 69% compared with Chord. It can decrease the discovery routing distance by 17% compared with JXTA and 83% compared with Chord depending on the environment.

• Journal of Ginseng Research
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• v.39 no.2
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• pp.141-147
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• 2015

Background: Adipocytes, which are the main cellular component of adipose tissue, are the building blocks of obesity. The nuclear hormone receptor $PPAR{\gamma}$ is a major regulator of adipocyte differentiation and development. Obesity, which is one of the most dangerous yet silent diseases of all time, is fast becoming a critical area of research focus. Methods: In this study, we initially aimed to investigate whether the ginsenoside Rf, a compound that is only present in Panax ginseng Meyer, interacts with $PPAR{\gamma}$ by molecular docking simulations. After we performed the docking simulation the result has been analyzed with several different software programs, including Discovery Studio, Pymol, Chimera, Ligplus, and Pose View. All of the programs identified the same mechanism of interaction between $PPAR{\gamma}$ and Rf, at the same active site. To determine the drug-like and biological activities of Rf, we calculate its absorption, distribution, metabolism, excretion, and toxic (ADMET) and prediction of activity spectra for substances (PASS) properties. Considering the results obtained from the computational investigations, the focus was on the in vitro experiments. Results: Because the docking simulations predicted the formation of structural bonds between Rf and $PPAR{\gamma}$, we also investigated whether any evidence for these bonds could be observed at the cellular level. These experiments revealed that Rf treatment of 3T3-L1 adipocytes downregulated the expression levels of $PPAR{\gamma}$ and perilipin, and also decreased the amount of lipid accumulated at different doses. Conclusion: The ginsenoside Rf appears to be promising compound that could prove useful in antiobesity treatments.

• Journal of the Korean Society for information Management
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• v.19 no.2
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• pp.159-179
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• 2002

The Dublin Core, MARC. IFLA-FRBR user communities are developing international standards for describing textual, physical and audiovisual resources to enable their resources discovery over the Internet. Therefore the metadata interoperability Problem has been exacerbated by the need for more complex metadata descriptions. In this paper we propose a new mechanism for metadata interoperability based on the new semantic web applications : IFLA-FRBR framework, INDECS metadata and an event-aware ABC models. This study introduces a new approach method which is essential to the generation of interoperable metadata descriptions, particularly in the context of multimedia contents.

• Journal of information and communication convergence engineering
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• v.6 no.3
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• pp.255-260
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• 2008

In the recently years, there has been a big interest in ad hoc wireless network as they have tremendous military and commercial potential. An Ad hoc wireless network is composed of mobile computing devices that use having no fixed infrastructure of a multi-hop wireless network formed. So, the fact that limited resource could support the network of robust, simple framework and energy conserving etc. In this paper, we propose a new ad hoc multicast routing protocol for based on the ontology scheme called inference network. Ontology knowledge-based is one of the structure of context-aware. And the ontology clustering adopts a tree structure to enhance resilient against mobility and routing complexity. This proposed multicast routing protocol utilizes node locality to be improve the flexible connectivity and stable mobility on local discovery routing and flooding discovery routing. Also attempts to improve route recovery efficiency and reduce data transmissions of context-awareness. We also provide simulation results to validate the model complexity. We have developed that proposed an algorithm have design multi-hierarchy layered networks to simulate a desired system.

• Journal of The Institute of Information and Telecommunication Facilities Engineering
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• v.10 no.4
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• pp.121-127
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• 2011

Many peer-to-peer (p2p) systems have been studied in distributed, ubiquitous computing environments. Distributed hash table (DHT)-based p2p systems can improve load-balancing even though locality utilization and user mobility are not guaranteed. We propose a mobile locality-based hierarchical p2p overlay network (MLH-Net) to address locality problems without any other services. MLH-Net utilizes mobility features in a mobile environment. MLH-Net is constructed as two layers, an upper layer formed with super-nodes and a lower layer formed with normal-nodes. Because super-nodes can share advertisements, we can guarantee physical locality utilization between a requestor and a target during any discovery process. To overcome a node failure, we propose a simple recovery mechanism. The simulation results demonstrate that MLH-Net can decrease discovery routing hops by 15% compared with JXTA and 66% compared with Chord.

• Journal of Plant Biotechnology
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• v.45 no.3
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• pp.228-235
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• 2018

In this study, two pepper varieties, PRH1 (powdery mildew resistance line) and Saengryeg (powdery mildew resistance line), were resequenced using next generation sequencing technology in order to develop InDel markers. The genome-wide discovery of InDel variation was performed by comparing the whole-genome resequencing data of two pepper varieties to the Capsicum annuum cv. CM334 reference genome. A total of 334,236 and 318,256 InDels were identified in PRH1 and Saengryeg, respectively. The greatest number of homozygous InDels were discovered on chromosome 1 in PRH1 (24,954) and on chromosome 10 (29,552) in Saengryeg. Among these homozygous InDels, 19,094 and 4,885 InDels were distributed in the genic regions of PRH1 and Saengryeg, respectively, and 198,570 and 183,468 InDels were distributed in the intergenic regions. We have identified 197,821 polymorphic InDels between PRH1 and Saengryeg. A total of 11,697 primers sets were generated, resulting in the discovery of four polymorphic InDel markers. These new markers will be utilized in order to identify disease resistance genotypes in breeding populations. Therefore, our results will make a one-step advancement in whole genome resequencing and add genetic resource datasets in pepper breeding research.

• Journal of Internet Computing and Services
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• v.20 no.2
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• pp.101-108
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• 2019

Workflow management systems (WfMSs) automate and manage workflows, which are implementations of organizational processes operated in process-centric organizations. In this paper, wepropose an algorithm to discover temporal work transference networks from workflow execution logs. The temporal work transference network is a special type of enterprise social networks that consists of workflow performers, and relationships among them that are formed by work transferences between performers who are responsible in performing precedent and succeeding activities in a workflow process. In terms of analysis, the temporal work transference network is an analytical property that has significant value to be analyzed to discover organizational knowledge for human resource management and related decision-making steps for process-centric organizations. Also, the beginning point of implementinga human-centered workflow intelligence framework dealing with work transference networks is to develop an algorithm for discovering temporal work transference cases on workflow execution logs. To this end, we first formalize a concept of temporal work transference network, and next, we present a discovery algorithm which is for the construction of temporal work transference network from workflow execution logs. Then, as a verification of the proposed algorithm, we apply the algorithm to an XES-formatted log dataset that was released by the process mining research group and finally summarize the discovery result.

• Journal of Internet Computing and Services
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• v.20 no.5
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• pp.49-55
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• 2019

Organizations design and operate business process models to achieve their goals efficiently and systematically. With the advancement of IT technology, the number of items that computer systems can participate in and the process becomes huge and complicated. This phenomenon created a more complex and subdivide flow of business process.The process instances that contain workcase and events are larger and have more data. This is an essential resource for process mining and is used directly in model discovery, analysis, and improvement of processes. This event log is getting bigger and broader, which leads to problems such as capacity management and I / O load in management of existing row level program or management through a relational database. In this paper, as the event log becomes big data, we have found the problem of management limit based on the existing original file or relational database. Design and apply schemes to archive and analyze large event logs through Hadoop, an open source distributed file system, and HBase, a NoSQL database system.

• The KIPS Transactions:PartD
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• v.10D no.2
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• pp.327-336
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• 2003

Recently the rapid growth of Internet and the construction of high speed networks make many kinds of multimedia services possible. But most of current multimedia services are designed being by client/server model, which incurs high load of central server. In order to solve this problem, we propose a peer-to-peer network-based discovery mechanism for multimedia services. In the proposed scheme, mobile agents that have autonomy and mobility are used to search the location of resources. Use of mobile agents can solve the loss problem of the search result that occurs when the network is unsettled in pure peer-to-peer network. It also supports interoperability in heterogeneous system environments. In the proposed scheme, each host maintains the location information of resources which are locally requested or recently requested by other hosts. So, the proposed scheme has faster response time than the pre-existing mechanisms in pure peer-to-peer network environments.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.46 no.4
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• pp.1-14
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• 2023

As markets and industries continue to evolve rapidly, technology opportunity discovery (TOD) has become critical to a firm's survival. From a common consensus that TOD based on a firm's capabilities is a valuable method for small and medium-sized enterprises (SMEs) and reduces the risk of failure in technology development, studies for TOD based on a firm's capabilities have been actively conducted. However, previous studies mainly focused on a firm's technological capabilities and rarely on business capabilities. Since discovered technologies can create market value when utilized in a firm's business, a firm's current business capabilities should be considered in discovering technology opportunities. In this context, this study proposes a TOD method that considers both a firm's business and technological capabilities. To this end, this study uses patent data, which represents the firm's technological capabilities, and trademark data, which represents the firm's business capabilities. The proposed method comprises four steps: 1) Constructing firm technology and business capability matrices using patent classification codes and trademark similarity group codes; 2) Transforming the capability matrices to preference matrices using the fuzzy function; 3) Identifying a target firm's candidate technology opportunities using the collaborative filtering algorithm; 4) Recommending technology opportunities using a portfolio map constructed based on technology similarity and applicability indices. A case study is conducted on a security firm to determine the validity of the proposed method. The proposed method can assist SMEs that face resource constraints in identifying technology opportunities. Further, it can be used by firms that do not possess patents since the proposed method uncovers technology opportunities based on business capabilities.