• Journal of Korean Neurosurgical Society
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• 제54권3호
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• pp.175-182
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• 2013

Objective : Intracavitary injection of beta-emitting radiation source for control of cystic tumors has been tried with a benefit of localized internal radiation. The authors treated cystic brain tumor patients with Holmium-166-chitosan complex (Ho-166-chico), composed of a beta-emitting radionuclide Holmium-166 and biodegradable chit polymer, and evaluated the safety and effective measurement for response. Methods : Twenty-two patients with recurrent cystic brain tumor and/or located in a deep or eloquent area were enrolled in this pilot study. The cyst volume and wall thickness were determined on CT or MRI to assess radiological response. The activity of Ho-166-chico injected via Ommaya reservoir was prescribed to be 10-25 Gy to the cyst wall in a depth of 4 mm. Results : There was neither complications related to systemic absorption nor leakage of Ho-166-chico in all 22 patients. But, two cases of oculomotor paresis were observed in patients with recurrent craniopharyngioma. Radiological response was seen in 14 of 20 available follow-up images (70%). Seven patients of 'evident' radiological response experienced more than 25% decrease of both cyst volume and wall thickness. Another 7 patients with 'suggestive' response showed decrease of cyst volume without definitive change of the wall thickness or vice versa. All patients with benign tumors or low grade gliomas experienced symptomatic improvement. Conclusion : Ho-166-chico intracavitary radiation therapy for cystic tumor is a safe method of palliation without serious complications. The determination of both minimal effective dosage and time interval of repeated injection through phase 1 trial could improve the results in the future.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2009년도 춘계학술대회 논문집
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• pp.361-364
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• 2009

KEPRI has studied planar type SOFC stacks using anode-supported single cells and kW class co-generation systems for residential power generation. A 1kW class SOFC system consisted of a hot box part, a cold BOP part and a water reservoir. A hot box part contains a SOFC stack made up of 48 cells with $10{\times}10cm^2$ area and ferritic stainless steel interconnectors, a fuel reformer, a catalytic combustor and heat exchangers. Thermal management and insulation system were especially designed for self-sustainable operation. A cold BOP part was composed of blowers, pumps, a water trap and system control units. When a 1kW class SOFC system was operated at $750^{\circ}C$ with hydrogen, the stack power was 1.2kW at 30 A and 1.6kW at 50A. Turning off an electric furnace, the SOFC system was operated using hydrogen and city gas without any external heat source. Under self-sustainable operation conditions, the stack power was about 1.3kW with hydrogen and 1.2kW with city gas respectively. The system also recuperated heat of about 1.1kW by making hot water. Recently KEPRI developed stacks using $15{\times}15cm^2$ cells and tested them. KEPRI will develop a 5 kW class CHP system using $15{\times}15cm^2$ stacks by 2010.

• 지질공학
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• 제26권4호
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• pp.497-503
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• 2016

가진발생장치를 이용한 시멘트 주입공법(CGVM)은 국내에서 개발된 건설 신기술로써 가진된 주입재가 대상지반으로 주입되어 지반보강 효율을 증대시키는 기술이다. 따라서 본 연구에서는 CGVM 공법의 현장적용 및 시공효과를 검증하는 것이 목적으로써 2개의 연구지역을 선정한 후 시공 전 후에 대해 표준관입시험과 현장투수시험 및 지구물리탐사 결과를 비교하였다. 표준관입시험을 통한 시공 전 후 비교 결과 N 값이 33.57~60.90% 증가된 것으로 나타났으며 현장투수시험의 경우 시공 후 투수계수가 감소된 것으로 보아 차수효과 및 저수지 제체의 안정성 증대 등을 기대할 수 있을 것으로 판단된다. 또한 전기비저항탐사 결과 시공 전에 비해 누수로 인한 저비저항대가 관찰되지 않아 그라우팅 효과가 매우 뛰어난 것으로 나타났다.

• 한국농공학회지
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• 제36권4호
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• pp.95-102
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• 1994

The series of the papers consist of three parts to describe the development, calibration, and applications of the flood forecasting models for the Youngsan Estuarine Dam located at the mouth of the Youngsan river. And this paper discusses the hydrologic model for inflow simulation at Naju station, which constitutes 64 percent of the drainage basin of 3521 .6km$^2$ in area. A simplified TANK model was formulated to simulate hourly runoff from rainfall And the model parameters were optirnized using historical storm data, and validated with the records. The results of this paper were summarized as follows. 1. The simplified TANK model was formulated to conceptualize the hourly rainfall-run-off relationships at a watershed with four tanks in series having five runoff outlets. The runoff from each outlet was assumed to be proportional to the storage exceeding a threshold value. And each tank was linked with a drainage hole from the upper one. 2. Fifteen storm events from four year records from 1984 to 1987 were selected for this study. They varied from 81 to 289rn'm The watershed averaged, hourly rainfall data were determined from those at fifteen raingaging stations using a Thiessen method. Some missing and unrealistic records at a few stations were estimated or replaced with the values determined using a reciprocal distance square method from abjacent ones. 3. An univariate scheme was adopted to calibrate the model parameters using historical records. Some of the calibrated parameters were statistically related to antecedent precipitation. And the model simulated the streamflow close to the observed, with the mean coefficient of determination of 0.94 for all storm events. 4. The simulated streamflow were in good agreement with the historical records for ungaged condition simulation runs. The mean coefficient of determination for the runs was 0.93, nearly the same as calibration runs. This may indicates that the model performs very well in flood forecasting situations for the watershed.

• 한국농공학회지
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• 제43권2호
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• pp.59-68
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• 2001

A water balance analysis was performed for a paddy field neighboring the Dongchang stream, downstream of the Unmun reservoir, which is constructed for the urban water supply. Daily rainfall data were collected and irrigation water flow rate, drainage flow rate, evaportranspiration, infiltration, and piezometeric head were measured in the field. The flow rates were continuously observed by water level logger during the growing season. The evaportranspiration and the infiltration were measured by N-type depletion meter and cylindrical infiltrometer, respectively. PVC pipes with 12mm diameter were used for piezometric head measurement. Total Irrigation and drainage flows were 3,608mm and 1,170mm in 1999, and 3,971mm and 1,548mm in 2000, respectively. The mean and range of the daily infiltration rate were 4.4mm/d and 3.4mm/d to 5.5mm/d in 1999 and 5.1mm/d and 4.1mm/d to 6.5mm/d in 2000, respectively. The net ground water flow including the change of soil water storage was 2,855mm in 1999 and 2,540mm in 2000. The evapotranspiration was 458.3mm in 1999 and 553.5mm in 2000. The range of daily evapotranspiration rate was from 1.6 to 8.7mm/d. The return flow ratio was about 32% in 1999 and 39% in 2000 and three year average was 35% including previous study in 1997. The amount of irrigation water was much higher than design standards or references in this study, This was caused by the inadequate water management practice in the area where water was oversupplied on farmers’ request rather than following sound water management principles.

• 한국방재학회 논문집
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• 제4권1호
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• pp.41-50
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• 2004

본 연구에서는 퍼지제어기법을 이용한 홍수조절 모형의 적용성을 파악하기 위해 한강수계 단일댐에 적용하였다. 개발된 모형들의 홍수조절능력을 비교하기 위해 1984, 1990, 1995년 대홍수 발생시 실제 운영실적과 본 연구에서 개발된 모형들의 가상운영결과를 비교하였다. 본 연구에서 개발한 3개 모형은 모두 실제 적용성을 고려하여 댐의 수위와 유입량이라는 2가지 정보량으로부터 방류량을 결정토록 하였으며, 최대방류량 역시 댐 설계시 기준인 허용최대방류량을 초과하지 않도록 하였다. 각 홍수사상에 대해 적용한 결과 기존의 댐 운영결과에 비해 홍수위를 낮출 수 있으면서도 하류부의 피해 최소화에도 적절한 것으로 나타나 퍼지제어모형의 적용성을 확인할 수 있었다.

• 농촌의학ㆍ지역보건
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• 제15권1호
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• pp.49-55
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• 1990

Zoonoses are those diseases and infections that are naturally transmitted between vertebrate animals and man. At present, approximately 175 diseases caused by virus, rickettsia, bacteria, protozoa and helminthes as well as some of arthropods and the number is continually increasing. Although zoonoses are generally recognized as significant health problems, the actual prevalence and incidence of zoonotic infections is difficult to determine. Medical services in a rural area are scarce and ill persons may have little chance to see a physician. Furthermore, a lack of physician awareness and of appropriate diagnostic support is made often misdiagnosis. In rural Korea, parasitic disease is still important subject in the field of zoonotic infections considering its number and morbidity. Recently there was conspicuous reduction of soil-transmitted parasitic diseases (i.e. ascariasis. hookworms, trichuriasis), but clonorchiasis. intestinal trematodiases and taeniasis are a considerable problem. This is often significantly related to human behavioral patterns based on socio-economic and cultural conditions and linked with the local biologic and physical environment. The most of all parasitic zoonoses to man and animals are the food-transmitted parasitic diseases, and domestic animals such as dog, cat, pig, as well as fat and some mammals, ruminants and birds are act as reservoir hosts. In the present topics, current problems of parasitic zoonoses caused by protozoan infections (i. e. toxoplasmosis, pneumocystosis and cryptosporidiosis) which are the most common opportunistic in AIDS or immunocompromised persons, trematode infections (i.e. clonorchiasis, paragonimiasis and some intestinal tremadodiases). cestode infections such as cysticercosis and sparganosis, and some nematode infections of anisakiasis, thelaziasis and strongyloidiasis, are discussed here those on the occurrence in man and animals and the source of transmission as well as prevention and control measures in Korea.

• 한국지리정보학회지
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• 제10권1호
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• pp.158-168
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• 2007

본 연구에서는 소양호유역의 탁수 및 토사유실 저감을 위해 수립중인 다양한 대책중 산림청과 지자체를 중심으로 계획중인 사방댐에 대한 저감효과를 분석하였다. 2005년 강우와 GIS 자료를 이용하여 분석한 결과 소양호유역의 토사유실은 4,819,494 ton으로 평가되었으며, 단위토사유실분석에서는 추곡천, 자운천 그리고 오항천이 다른 유역들에 비해 높은 값을 보였다. 94개의 사방댐 지점을 중심으로 GIS 공간분석을 이용하여 사방댐유역을 추출하였으며, 사방댐유역의 토사유실량과 유사운송비를 이용하여 저감효과를 분석한 결과, 2005년 사방댐의 토사유실저감효과는 6.8%(330,203 ton)으로 분석되었다. 또한 사방댐의 위치를 5,000 ton 이상인 지역으로 이동한 시나리오에서의 사방댐의 토사유실저감효과는 10.5%(506,783 ton)으로 증가되었다.

• 대한토목학회논문집
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• 제5권1호
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• pp.91-100
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• 1985

본(本) 연구(硏究)는 한강유역(漢江流域) 댐군(群)의 비상사태하(非常事態下)(큰 홍수파(洪水波) 유하시(流下時))에서의 수문조작(水門操作) 기준설정(基準設定)에 관한 것으로 얻어진 결과(結果)는 다음과 같다. 1) 수문조작(水門操作)을 저수위(貯水位)와 유입량(流入量)으로 실시(實施)할 수 있게끔 6개 댐(화천(華川), 춘천(春川), 소양강(昭陽江), 의암(衣岩), 청평(淸平), 인당(人堂)댐)에 대해 수문조작(水門操作) 기준(基準)을 수식화(數式化)하였다. 2) 수문(水門)의 개방면적(開放面積), 유입량(流入量), 저수위(貯水位), 방류량(放流量) 간의 다중회귀분석(多重回歸分析)에 의해서 얻어진 식(式)으로 홍수추적(洪水追跡)을 실시한 결과 그 적용가능성(適用可能性)을 확인(確認)하였다. 3) 본(本) 연구(硏究)에서 얻어진 수문조작(水門操作) 기준(基準)과 홍수추적방법(洪水追跡方法)을 사용(使用)하여 비상사태하(非常事態下)(큰 홍수파(洪水波) 유하시(流下時))에서의 각 댐을 검토(檢討)한 바, 모두 안전(安全)하였으나, 소양강(昭陽江), 의암(衣岩), 청평(淸平)댐만은 저수지(貯水池) 초기방류수위(初期放流水位)를 미리 저하(低下)시킨 상태(狀態)에서 수문조작(水門操作)이 이루어져야 할 것이다.

• 대한기계학회논문집B
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• 제36권5호
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• pp.545-551
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• 2012

마이크로 유체구조를 기반으로 하는 약물전달장치는 마이크로 유체 채널형상의 간단한 변형만으로 약물분출량을 쉽게 조절할 수 있는 장점이 있다. 그러나 디바이스 제작에 사용된 생분해성 고분자 85/15poly(lactic-co-glycolic acid) (85/15PLGA)의 소수성 기질 때문에 약물전달 장치내부로의 release medium의 유입이 원활하게 이루어지지 않으며 그 결과, 디바이스의 임플랜트 후 초기의 약물 분출에 영향을 줄 것으로 예상된다. 따라서 surfactant인 polyethylene-glycol600 (PEG600)과 Tween80을 이용하여 micro-channel의 표면처리를 한 디바이스와 surfactant를 사용하지 않은 디바이스를 각각 제작하여 약물 전달 실험을 하였으며, 이를 바탕으로 마이크로 유체 채널의 기하학적 형상에 따른 국소 마취제의 일종인 bupivacaine HCl(BHCl)의 분출속도제어를 입증하였다.