• Environmental and Resource Economics Review
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• v.19 no.3
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• pp.547-569
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• 2010

The purpose of this study is to estimate the benefits associated with the opportunities of multiple destination trips using a mixed logit model. The opportunities that affect the destination choice can be one of the external environments of recreational sites. The data for this study were taken from a survey conducted to the multiple destination trip participants at Seorak National Park in Korea. The results of the research show the specific values of complementary opportunities in the study area.

• Journal of Smart Tourism
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• v.1 no.3
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• pp.17-20
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• 2021

Technology and tourism have become inseparable, and technological innovations propose new services to the tourism industry. During the current pandemic, service robot usage has increased more than at any other time which comes with advantages and disadvantages. This paper discusses the opportunities and challenges of utilizing service robots in the service industry during and after the pandemic crisis. The study follows a content analysis methodology. Findings indicate that service robots are easy to access, offer an alternative form of communication, reduce costs and boost operational safety; in contrast, robotics increase unemployment and cause anxiety and depression among the demoralized employees.

• International Journal of Railway
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• v.2 no.2
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• pp.80-92
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• 2009

Successful market adoption of rail freight transport innovations that might offer opportunities for market share increase is the focus of this paper. Firstly, seen from a theoretical point of view, it is not incremental innovations but radical organizational and transformation innovations that are likely to increase the market share of rail freight transport. Secondly, the particular inovations that offer some success potential for market adoption are: dedicated infrastructure, the fixed timetable, locomotive upgrades, and INTERFACE. Thirdly, unfortunately, the opportunities to increase the market share of rail freight transport appear to be limited.

• Molecules and Cells
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• v.46 no.10
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• pp.579-588
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• 2023

Sarcomas are rare and heterogeneous mesenchymal neoplasms originating from the bone or soft tissues, which pose significant treatment challenges. The current standard treatment for sarcomas consists of surgical resection, often combined with chemo- and radiotherapy; however, local recurrence and metastasis remain significant concerns. Although immunotherapy has demonstrated promise in improving long-term survival rates for certain cancers, sarcomas are generally considered to be relatively less immunogenic than other tumors, presenting substantial challenges for effective immunotherapy. In this review, we examine the possible opportunities for sarcoma immunotherapy, noting cancer testis antigens expressed in sarcomas. We then cover the current status of immunotherapies in sarcomas, including progress in cancer vaccines, immune checkpoint inhibitors, and adoptive cellular therapy and their potential in combating these tumors. Furthermore, we discuss the limitations of immunotherapies in sarcomas, including a low tumor mutation burden and immunosuppressive tumor microenvironment, and explore potential strategies to tackle the immunosuppressive barriers in therapeutic interventions, shedding light on the development of effective and personalized treatments for sarcomas. Overall, this review provides a comprehensive overview of the current status and potential of immunotherapies in sarcoma treatment, highlighting the challenges and opportunities for developing effective therapies to improve the outcomes of patients with these rare malignancies.

• The Journal of Asian Finance, Economics and Business
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• v.5 no.2
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• pp.63-72
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• 2018

Researches based on the pattern of planned behavior holds that the three variables of entrepreneurial attitudes, subjective norms, and perceived behavior control influence each other and influence entrepreneurial intentions respectively. However, there are also different, even conflicting research conclusions that continue to emerge. Researches based on the pattern of alertness, believe that profit opportunities and individuals' pursuit to truth are the driving forces. Many scholars have demonstrated the impact of individual entrepreneurial alertness on entrepreneurial intentions. However, as an exogenous causal agent, profit opportunities have a logical problem: if there are no other assumptions, the mere existence of opportunities does not adequately explain entrepreneurial alertness. To address this gap, this study considered samples from mainland China, where entrepreneurial activities are very active currently, to test the role that entrepreneurial alertness is assumed to play in the planned behavior model. The results show that the three dimensions of alertness, individually partly intermediate the influence of entrepreneurial attitude on entrepreneurial intention, the influence of subjective norms on entrepreneurial intention, and that of perceived behavior control on entrepreneurial intention. This article studied the production of entrepreneurial intention by integrating the two patterns of planned behavior and alertness through empirical analysis, and opened up a new field for subsequent research on entrepreneurial intention.

• Journal of Korean Society of Forest Science
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• v.94 no.2 s.159
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• pp.61-66
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• 2005

This research is based on a visitor survey at Jogyesan Provincial Park in Jeonnam, and its implications for interpretive planning. The research population was the set of weekend and holiday visitors, 20 years of age and older, to Jogyesan Provincial Park in Jeonnam, during the summer of 2003. A questionnaire was offered to every tenth person entering the park on every other weekend day and both holidays (June 1 and September 30). It was obvious that the interpretive program at Jogyesan Provincial Park, to meet the expectations of its visitors, should provide: (1) visitors with opportunities to experience the out-of-doors and learn about the cultural, historical and natural surroundings; (2) opportunities for the visitors to relax and escape from the normal and work environment; and (3) opportunities for the visitors to experience an atmosphere which enables them to achieve and self-actualize. In the area of interpretive programs, expectations are usually priorities, except for mountain climbing and exercise. Enhancing achievement and self-actualization is rarely a consideration and needs more emphasis in the future interpretive programs and plans.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.34 no.2
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• pp.133-140
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• 2023

Objectives: The coronavirus disease pandemic affected people's lives in different ways, including child education and parent-child interactions. The present study aimed to identify the educational opportunities of children and challenges of parents during this pandemic. Methods: This study was conducted using a qualitative and phenomenological method. The participants were 23 parents of children aged 7-12 years, selected by purposive sampling method. Data were collected by semi-structured interviews, which continued until data saturation was reached, and then classified and processed following Strauss and Glasser's approach. Results: The findings were classified as parenting transformation, attachment challenges, and parenting challenges due to macro-systemic changes. Online education and changes caused by social distancing were the most significant parenting challenges. Moreover, children did not have the necessary space to be independent and self-sufficient. Conclusion: For many children, adapting to virtual education has been challenging; therefore, parents should change their parenting control and support. The emergence of such challenges has led to the creation of more opportunities in the field of child education.

• Proceedings of the Korean Society of Developmental Biology Conference
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• 2003.10a
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• pp.29-48
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• 2003

It is remarkable that nuclear transfer using differentiated donor cells can produce physiologically normal cloned animals, but the process is inefficient and highly prone to epigenetic errors. Aberrant patterns of gene expression in clones contribute to the cumulative losses and abnormal phenotypes observed throughout development. Any long lasting effects from cloning, as revealed in some mouse studies, need to be comprehensively evaluated in cloned livestock. These issues raise animal welfare concerns that currently limit the acceptability and applicability of the technology. It is expected that improved reprogramming of the donor genome will increase cloning efficiencies realising a wide range of new agricultural and medical opportunities. Efficient cloning potentially enables rapid dissemination of elite genotypes from nucleus herds to commercial producers. Initial commercialization will, however, focus on producing small numbers of high value animals for natural breeding especially clones of progeny-tested sires, The continual advances in animal genomics towards the identification of genes that influence livestock production traits and human health increase the ability to genetically modify animals to enhance agricultural efficiency and produce superior quality food and biomedical products for niche markets. The potential opportunities in animal agriculture are more challenging than those in biomedicine as they require greater biological efficiency at reduced cost to be economically viable and because of the more difficult consumer acceptance issues. Nevertheless, cloning and transgenesis are being used together to increase the genetic merit of livestock; however, the integration of this technology into farming systems remains some distance in the future.

• The Journal of Asian Finance, Economics and Business
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• v.9 no.1
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• pp.399-408
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• 2022

This paper aims to evaluate the effects of Critical work factors on Work Motivation and Job Satisfaction of young Vietnamese employees. The four most essential work aspects were consisting of the Work environment, Employee empowerment, Salary, and Promotion opportunities. To empirically evaluate the proposed research model, the authors assemble data through conducting questionnaire interviews with young employees working in Vietnamese firms. A sample of 216 respondents was constructed using the PLS-SEM program to highlight the testing of thirteen hypotheses. The testing results indicate that four Critical work factors positively impact the job motivation of young employees, especially two factors as Salary and Promotion opportunities. Surprisingly, the hypothesis regarding the positive direct relationship between Promotion opportunities and Job satisfaction is not supported. Meanwhile, the rest influence factors have a significant connection with the Vietnamese worker's job satisfaction. The mediation role of Work motivation was also tested by examining the indirect positive relationship between four Critical work factors and Job satisfaction. This paper is the first study that focuses on young employees; hence, these research findings provide Vietnamese human resource managers some suggestions for reference, which can be considered the dynamic factors on the young Vietnamese employees.

• Proceedings of the Korean Society of Embryo Transfer Conference
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• 2003.10a
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• pp.29-48
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• 2003

It is remarkable that nuclear transfer using differentiated donor cells can produce physiologically normal cloned animals, but the process is inefficient and highly prone to epigenetic errors. Aberrant patterns of gene expression in clones contribute to the cumulative losses and abnormal phenotypes observed throughout development. Any long lasting effects from cloning, as revealed in some mouse studies, need to be comprehensively evaluated in cloned livestock. These issues raise animal welfare concerns that currently limit the acceptability and applicability of the technology. It is expected that improved reprogramming of the donor genome will increase cloning efficiencies realising a wide range of new agricultural and medical opportunities. Efficient cloning potentially enables rapid dissemination of elite genotypes from nucleus herds to commercial producers. Initial commercialisation will, however, focus on producing small numbers of high value animals for natural breeding especially clones of progeny-tested sires. The continual advances in animal genomics towards the identification of genes that influence livestock production traits and human health increase the ability to genetically modify animals to enhance agricultural efficiency and produce superior quality food and biomedical products for niche markets. The potential opportunities inanimal agriculture are more challenging than those in biomedicine as they require greater biological efficiency at reduced cost to be economically viable and because of the more difficult consumer acceptance issues. Nevertheless, cloning and transgenesis are being used together to increase the genetic merit of livestock; however, the integration of this technology into farming systems remains some distance in the future.