• 대한기계학회논문집 C: 기술과 교육
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• 제3권3호
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• pp.165-173
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• 2015

본 논문에서는 PRT(Personal Rapid Transit) 차량의 수직이송을 위한 장치를 개발하는 과정에서 수행된 주요 구조물의 정적 구조적 안전성 평가 결과를 다룬다. 지금까지 노선상에서 승객이 탑승한 상태에서 운영중인 차량의 수직이송에 대한 연구는 전무하며, 이는 기존의 2 차원 적인 교통운영 체계의 한계를 극복하는데 기여할 수 있을 것으로 기대된다. 특히, 본 연구에서 제안된 수직이송장치는 순환컨베이어 방식으로 연속 이송이 가능해서 통행량이 많은 지역에도 적용이 가능하다. 본 시스템이 물류분야에서 많이 사용되어 왔지만, 수직이동 시 차량의 무게에 의한 하중은 일반적인 물류의 수송과는 다르게 집중하중 형태로 컨베이어에 가해지기 때문에 이에 대한 구조적 안정성 평가는 필수적이다. 본 논문에서는 상용 유한요소 해석 프로그램인 $Ansys^{(R)}$를 이용해서 수직이송 장치의 기본 설계(안)의 구조적 안정성을 수치해석적 방법에 의해 평가하고자 한다.

• 한국미생물·생명공학회지
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• 제52권1호
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• pp.44-54
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• 2024

One of the serious modern environmental problems is pollution caused by highly toxic pesticides. Only small amounts of applied pesticides reach their target, and the rest ends up in soil and water. Chlorpyrifos is a toxic, broad-spectrum organophosphate insecticide. In humans, chlorpyrifos inhibits acetylcholinesterase (AChE) in the peripheral and central nervous system, and particularly in children, small amounts of this pesticide cause neurotoxic damage. As the toxic effects of chlorpyrifos and its persistence in the environment require its removal from contaminated sites, it is essential to study the biological diversity of chlorpyrifos-degrading microorganisms. In this study, we sought to determine the chlorpyrifos-degrading ability of the bacterial strain Ochrobactrum intermedium PDB-3. This strain was isolated from soil contaminated with various pesticides and identified as PDB-3 based on morpho-cultural characteristics, MALDI-TOF MS, and 16S rRNA. Studies were conducted for 30 days in sterile soils containing initial concentrations of 50, 75, 100, and 125 mg/kg of chlorpyrifos. To determine the degradation of chlorpyrifos, a liquid culture of the strain was added to the soil at three optical densities: 0, and after 24 and 48 h (OD = 0.03, 0.2 and 0.32). Using GX-MS, we determined that chlorpyrifos was converted to 3,5,6-trichloro-2-pyridinol (TCP). We also found that with increasing optical density, rapid degradation of the initial concentration of chlorpyrifos occurred. Sterile soil without strain PDB-3 was used as a control sample.

• 대한간호학회지
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• 제54권1호
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• pp.1-17
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• 2024

Purpose: The significance of the healthcare industry has grown exponentially in recent years due to the impact of the fourth industrial revolution and the ongoing pandemic. Accordingly, this study aimed to examine domestic healthcare-related patents comprehensively. Big data analysis was used to present the trend and status of patents filed in nursing. Methods: The descriptive review was conducted based on Grant and Booth's descriptive review framework. Patents related to nursing was searched in the Korea Intellectual Property Rights Information Service between January 2016 to December 2020. Data analysis included descriptive statistics, phi-coefficient for correlations, and network analysis using the R program (version 4.2.2). Results: Among 37,824 patents initially searched, 1,574 were selected based on the inclusion criteria. Nursing-related patents did not specify subjects, and many patents (41.4%) were related to treatment in the healthcare delivery phase. Furthermore, most patents (56.1%) were designed to increase effectiveness. The words frequently used in the titles of nursing-related patents were, in order, "artificial intelligence," "health management," and "medical information," and the main terms with high connection centrality were "artificial intelligence" and "therapeutic system." Conclusion: The industrialization of nursing is the best solution for developing the healthcare industry and national health promotion. Collaborations in education, research, and policy will help the nursing industry become a healthcare industry of the future. This will prime the enhancement of the national economy and public health.

• Nutrition Research and Practice
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• 제12권3호
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• pp.199-207
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• 2018

BACKGROUND/OBJECTIVES: Fermented Laminaria japonica (FL), a type sea tangle used as a functional food ingredient, has been reported to possess cognitive improving properties that may aid in the treatment of common neurodegenerative disorders, such as dementia. MATERIALS/METHODS: We examined the effects of FL on scopolamine (Sco)- and ethanol (EtOH)-induced hippocampus-dependent memory impairment, using the Passive avoidance (PA) and Morris water maze (MWM) tests. To examine the underlying mechanisms associated with neuroprotective effects, we analyzed acetylcholine (ACh) and acetylcholinesterase (AChE) activity, brain tissue expression of muscarinic acetylcholine receptor (mAChR), cAMP response element binding protein (CREB) and extracellular signal-regulated kinases 1/2 (ERK1/2), and immunohistochemical analysis, in the hippocampus of mice, compared to current drug therapy intervention. Biochemical blood analysis was carried out to determine the effects of FL on alanine transaminase (ALT), aspartate transaminase (AST), and triglyceride (TG) and total cholesterol (TC) levels. 7 groups (n = 10) consisted of a control (CON), 3 Sco-induced dementia and 3 EtOH-induced dementia groups, with both dementia group types containing an untreated group (Sco and EtOH); a positive control, orally administered donepezil (Dpz) (4mg/kg) (Sco + Dpz and EtOH + Dpz); and an FL (50 mg/kg) treatment group (Sco + FL50 and EtOH + FL50), orally administered over the 4-week experimental period. RESULTS: FL50 significantly reduced EtOH-induced increase in AST and ALT levels. FL50 treatment reduced EtOH-impaired step-through latency time in the PA test, and Sco- and EtOH-induced dementia escape latency times in the MWM test. Moreover, anticholinergic effects of Sco and EtOH on the brain were reversed by FL50, through the attenuation of AChE activity and elevation of ACh concentration. FL50 elevated ERK1/2 protein expression and increased p-CREB (ser133) in hippocampus brain tissue, according to Western blot and immunohistochemistry analysis, respectively. CONCLUSION: Overall, these results suggest that FL may be considered an efficacious intervention for Sco- and EtOH-induced dementia, in terms of reversing cognitive impairment and neuroplastic dysfunction.

• 디지털융복합연구
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• 제14권9호
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• pp.495-504
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• 2016

본 연구는 신체억제에 대한 인식과 태도를 파악하기 위해 노인요양시설의 요양보호사를 대상으로 시도된 조사연구이다. 연구대상자는 노인요양시설에 근무하는 요양보호사 153명을 대상으로 하였다. 자료수집은 구조화된 설문지를 사용하였고 수집한 자료는 기술통계 및 t-test, ANOVA, $Scheff{\acute{e}}$ test 및 Pearson Correlation Coefficient로 분석하였다. 연구 대상자의 신체억제에 대한 인식 정도는 전체평균 2.83점(5점 만점)이었고, 대상자의 신체억제에 대한 태도 정도는 전체평균 3.56점(5점 만점)이었다. 대상자의 신체억제에 대한 인식과 태도 간에는 통계적으로 유의한 순상관관계(r=.31, p<.001)가 있는 것으로 나타났다. 본 연구결과 신체억제에 대한 인식과 태도 점수가 낮은 문항에 대한 체계적인 교육의 필요성을 확인하였다. 따라서 신체억제의 적절한 사용방법에 관한 실제적이고 효과적인 교육프로그램의 개발이 필요하며, 신체억제 적용기준과 관련된 지침개발이 필요하다. 향후 노인의 인권보호를 위해 신체억제 감소 및 폐지를 위한 노력과 관심이 요구된다.

• 한국과학교육학회지
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• 제33권7호
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• pp.1285-1299
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• 2013

우리나라 과학교육에서는 과학 창의성의 계발을 강조하고 있다. 본 연구에서는 과학 창의성으로서 과학자들의 문제 발견에서 나타나는 패턴을 탐색하는데 목적을 두었다. 사례별 당시의 과학사적 상황, 문제 발견의 과정 및 문제 해결에 대한 내용을 구체적으로 논의하였다. 연구 결과, 과학자 10명이 과학사적 사건을 발견할 때 특징적으로 나타내는 문제 발견의 패턴은 다음과 같은 5가지 패턴으로 발견되었다. 패턴 1의 경우는 당시의 이론이나 설명이 불충분하거나 모순 또는 오류를 발견함에 의해 과학적 문제를 발견하는 것으로, 여기에는 라부아지에, 멘델, 왓슨의 문제 발견이 포함되었다. 패턴 2의 경우는 당대의 지식으로는 설명되지 않는 이상한 현상을 관찰함에 의해 문제를 발견하는 것으로, 여기에는 러더퍼드와 뢴트겐의 문제 발견이 포함되었다. 패턴 3의 경우는 비유 추론에 의해 문제를 발견하는 것으로, 카르노와 영의 문제 발견이 포함되었다. 패턴 4의 경우는 새롭게 발명된 관찰 또는 측정 기구를 사용하여 새로운 현상을 관찰함으로써 문제를 발견하는 것으로, 갈릴레이의 문제 발견이 포함되었다. 패턴 5의 경우는 연구 프로젝트 수행 중에 그 연구와 관련된 새로운 문제를 발견하는 것으로, 패러데이와 케플러의 문제 발견이 포함되었다.

• Fashion, Industry and Education
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• 제14권2호
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• pp.35-46
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• 2016

The purpose of this study was to examine female consumers' attitudes and purchase intentions toward intimate apparel brands. To understand female consumers' shopping behaviors for intimate apparel products, this study examined interrelationships among brand familiarity, perceived risk, attitudes, and purchase intentions toward intimate apparel brands. A conceptual model was developed by adopting perceived risk theory (Cox, 1967) and theory of reasoned action (Ajzen & Fishbein, 1980). A pre-survey using a paper and pencil was conducted to identify the most familiar intimate apparel brand to young female consumers. The majority of pre-survey respondents (66 female college students) indicated Victoria's Secret as the most prominent intimate apparel brand. Therefore, Victoria's Secret was used to examine possible effects of brand familiarity on perceived risk and attitudinal and behavioral responses toward the brand. Using a web-based survey, 384 complete responses were collected from young female college students between the ages of 18-29 at a Mid-southern U.S. university. A structural equation modeling was employed to test the proposed research model and hypotheses. Results showed positive, statistically significant associations among the four variables (e.g., brand familiarity, perceived risk, attitudes, and purchase intentions). The findings suggested that young female consumers who are familiar with a particular intimate apparel brand are likely to perceive a low level of risk, leading to positive, strong attitudes with purchase intentions toward that particular intimate apparel brand. This suggests establishing brand familiarity through integrated marketing communication is crucial for risk reduction strategy in intimate apparel shopping.

• 임상간호연구
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• 제20권2호
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• pp.256-266
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• 2014

Purpose: This study was done to identify the level of knowledge on and stress from delirium among recovery room nurses, and correlations between these factors. Methods: In this study, 125 nurses agreed to participate in the study were surveyed from October 8 to October 28, 2013. Data were analyzed using t-test, ANOVA, $Scheff{\grave{e}}$ test and Pearson correlation. Results: Average percentage of correct answers to questions about delirium was 81.9% and the mean score was 26.22 (${\pm}5.01$). The mean score for recovery room nurses' work stress from emergency delirium was 3.86 (${\pm}0.99$). Extent of knowledge on delirium significantly differed by age (F=15.017, p<.001), length of clinical experience (F=22.132, p<.001), length of recovery room experience (F=10.538, p<.001), education (F=3.312, p =.040), and marital status (t=4.107, p<.001). Stress from ED was significantly related to age (F=9.185, p<.001), clinical experience (F=7.077, p=.001), and marital status (t=-2.027, p =.045). Knowledge on delirium had a negative relationship with stress from delirium (r=-.514, p<.001). Conclusion: Results show that nurses gained knowledge of delirium from their own clinical experience indicating a need to develop educational programs to improve knowledge on delirium and plans to reduce stress from delirium for recovery room nurses.

• Parasites, Hosts and Diseases
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• 제53권5호
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• pp.535-543
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• 2015

Integrated control strategies are important for sustainable control of schistosomiasis and soil-transmitted helminthiasis, despite their challenges for their effective implementation. With the support of Good Neighbors International in collaboration with National Institute of Medical Research, Mwanza, Tanzania, integrated control applying mass drug administration (MDA), health education using PHAST, and improved safe water supply has been implemented on Kome Island over 5 years for controlling schistosomiasis and soil-transmitted helminths (STHs). Baseline surveys for schistosomiasis and STHs was conducted before implementation of any integrated control strategies, followed by 4 cross-sectional follow-up surveys on randomly selected samples of schoolchildren and adults in 10 primary schools and 8 villages, respectively, on Kome islands. Those follow-up surveys were conducted for impact evaluation after introduction of control strategies interventions in the study area. Five rounds of MDA have been implemented from 2009 along with PHAST and improved water supply with pumped wells as other control strategies for complementing MDA. A remarkable steady decline of schistosomiasis and STHs was observed from 2009 to 2012 with significant trends in their prevalence decline, and thereafter infection rate has remained at a low sustainable control. By the third follow-up survey in 2012, Schistosoma mansoni infection prevalence was reduced by 90.5% and hookworm by 93.3% among schoolchildren while in adults the corresponding reduction was 83.2% and 56.9%, respectively. Integrated control strategies have successfully reduced S. mansoni and STH infection status to a lower level. This study further suggests that monitoring and evaluation is a crucial component of any large-scale STH and schistosomiasis intervention.

• 한국학교ㆍ지역보건교육학회지
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• 제22권4호
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• pp.49-60
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• 2021

Objectives: Laboratories have various latent physical, chemical, biological, and ergonomical factors according to the diversification and fusion of research and development activities. This study aims to investigate the chemical exposure concentrations of college laboratories and evaluate their health risks, and use them as basic data to promote the health of college students. Methods: The sampling and analysis of harmful chemicals in the air in laboratories were performed using Method 1500 of the U.S. National Institute for Occupational Safety and Health (NIOSH)의 Method 1500. The harmful chemicals in the laboratories were divided into carcinogenic and non-carcinogenic chemicals. Risk assessment was performed using the cancer risk (CR) for carcinogenic chemicals and using the hazard index (HI) for non-carcinogenic chemicals. Results: The harmful chemicals in college laboratories consisted of acetone, diethyl ether, methylene chloride, n-hexane, ethyl acetate, chloroform, tetrahydrofuran, toluene, and xylenes. They showed the highest concentrations in laboratories A (acetone 0.001~2.34ppm), B (chloroform 0.95~6.35ppm), C (diethyl ether 0.08~8.68ppm), and D (acetone 0.07~14.96ppm). The risk assessment result for non-carcinogenic chemicals showed that the HI of methylene chloride was 2.052 for men and 2.333 for women, the HI of N-hexane was 4.442 for men and 5.05 for women. Thus, the HI values were higher than 1. The risk of carcinogenic chemicals is determined by an excess cancer risk (ECR) value of 1.0×10^-5, which means that one in 100,000 people has a cancer risk. The ECRs of chloroform exceeded 1.0×10^-5 for both men and women, indicating the possibility of cancer risk. Conclusion: College laboratories showed the possibility of non-carcinogenic health risks for methylene chloride, n-hexane, tetrahydrofuran (THF), toluene, and xylenes, and carcinogenic health risks for chloroform, methylene chloride. However, this study used the maximum values of measurements to determine the worst case, and assumed that the subjects were exposed to the corresponding concentrations continuously for 8 hours per day for 300 days per year. In consideration of the nature of laboratory environment in which people are intermittently exposed, rather than continuously, to the chemicals, the results of this study has an element of overestimation.