• Journal of Forest and Environmental Science
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• 제39권2호
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• pp.73-80
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• 2023

Little is known of the life history of Garcinia kola; the objective of this study, therefore, was to assess the fruiting age and tree size of the species in a coastal humid tropical climate plantation condition. A total 103 trees were used in the study viz; 80 ten-year-old trees at reproductive maturity onset and 13 thirty-year-old trees with several cycles of reproduction that constitute two independent variables. Data collected were age of onset of flowering and size at reproductive maturity onset. Relative size at reproductive maturity onset (RSOM) was estimated as size at reproductive maturity onset (SOM) divided by asymptotic maximal size (AMS). Data analysis was conducted using pairwise t-test and principal component analysis (PCA). Reproductive maturity onset (flowering) was recorded in the ten-year-old stand eight (8) years after planting. Mean size at reproductive maturity onset (SOM) was height 5.32±1.7 m, dbh 0.11±0.03 m, total number of branches was 29.6±7.3, crown depth 5.24±1.05 m, crown diameter was 4.78±0.7 m, branch diameter 0.098±0.01 m, leaf length 0.13±0.02 m, leaf breadth 0.37±0.01 m, twig length 0.35±0.11 m and leaf per twig 6±0.84 and asymptotic maximal size (AMS) was height 19.85±0.76 m, dbh 0.95±0.09 m, total number of branches 62±5, crown depth 18.83±0.7 m, crown diameter 12.5±1.64 m, branch diameter 0.5±1.6 m, leaf length 0.16±0.023 m, leaf breadth 0.45±0.12 m, twig length 0.37±0.11 m and leaf per twig 19±7.5. Pairwise t-test analysis showed there was significant differences between SOM and AMS in all growth factors except leaf length, leaf breadth, and twig length. Highest relative size at reproductive maturity onset (RSOM) was recorded in leaf length 0.82, twig length 0.82, and leaf breadth 0.80, while, the lowest was branch diameter 0.11. Four components out of the total of eleven were extracted to explain the relationship in RSOM: Principal component one (PC1) explained 37.23%; PC2 26.4%, PC3 22.73%, and PC4 13.64%.

• 한국발생생물학회지:발생과생식
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• 제27권3호
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• pp.117-126
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• 2023

Bariatric surgery is an effective treatment option for obesity, but its effects on reproductive hormones are not well understood. This study aimed to investigate the impact of bariatric surgery on estrogen and progesterone levels in women with obesity. This was a prospective study that included 87 women with obesity who underwent bariatric surgery and 87 control women with obesity who did not. Blood samples were collected at baseline and at 3-month and 6-month follow-up periods to measure reproductive hormones and Adiponectin as well as medical history and physical examination for endometriosis and polycystic ovary syndrome (PCOS). The study found that sleeve gastrectomy significantly increased follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels in the bariatric surgery group compared to the control group at 3 and 6-month follow-up. There was no significant difference in the mean levels of estrogen and progesterone between the two groups at the 3-month follow-up period. Bariatric surgery leads to significant weight loss in women with obesity, but it does not seem to have a significant impact on estrogen and progesterone levels in the short-term. Future studies with longer follow-up periods are needed to investigate the long-term effects of bariatric surgery on reproductive hormones.

• Clinical and Experimental Reproductive Medicine
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• 제37권4호
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• pp.361-368
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• 2010

목적: 중격자궁은 흔하게 보고되는 선천성 자궁기형 중 하나이며 여성의 생식능력에 미치는 영향에 대해 아직 이견이 많고, 따라서 치료의 필요성에 대해서도 아직 정립되지 않았다. 본 연구에서는 중격자궁의 존재 및 치료 여부가 생식수행에 미치는 영향에 대해 알아보고자 하였다. 연구방법: 2008년 1월부터 2009년 12월까지 불임 또는 습관성 유산을 주소로 제일병원 산부인과를 방문하여 자궁난관 조영술을 시행한 총 2,838명의 환자들 중 중격자궁이 진단된 44명의 환자들을 대상으로 하였으며, 이 중 27명은 자궁경 하 자궁중격 절제술을 시행 받았으며, 17명은 진단 후 추가적인 치료를 받지 않았다. 대조군은 동일 기간 내에 자궁기형이 진단되지 않은 환자 42명을 나이를 고려 후 무작위 선정하였다. 연구 대상군의 임신율, 자연유산율, 그리고 생존분만율 등에 대한 의무기록을 후향적으로 분석하였으며, 대상군들의 평균 추적 관찰 기간은 진단 후 21.8개월 이었다. 결과: 추적 관찰 기간 중 자궁경 하 질식 자궁중격 절제술을 시행 받은 환자 (n=27)의 55.6% (15/27)가 임신에 성공한 반면 치료를 받지 않은 환자 (n=17)의 약 23.5% (4/17)만이 임신에 성공하여 치료받은 군에서 통계적으로 의미있는 높은 수치를 보였다 (p<0.05). 한편 생존분만율은 치료를 받은 환자군 및 자궁기형이 진단되지 않은 불임 또는 습관성 유산 환자 (대조군, n=42)에서 각각 75%와 84.6%를 보인 반면 치료 받지 않은 군에서는 50% (2/4)를 보여 치료 받지 않은 중격자궁 환자에서 낮은 경향을 보이지만 통계학적 의미는 없었다. 결론: 중격자궁이 생식수행에 미치는 영향은 자연유산 등 산과적 합병증 뿐 아니라 오히려 임신력의 저하에 더 큰 악영항을 미칠 수 있으며 불임 환자에서 중격자궁의 존재 시 적극적인 치료가 임신성공률의 향상에 도움이 될 것으로 생각 되지만 보다 명확한 결론을 위해 규모가 크고 관찰 기간이 긴 대단위 연구가 필요 할 것으로 생각된다.

• Clinical and Experimental Reproductive Medicine
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• 제43권1호
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• pp.51-53
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• 2016

Uterine fibroids are benign tumors of the myometrium with a diverse range of manifestations. Fibroids can dramatically increase in size during pregnancy due to the increase in estrogen levels. After delivery, the fibroids usually shrink back to their pre-pregnancy size. Uterine myomas may have many complications, including abnormal uterine bleeding, infertility, pressure on nearby organs, degeneration, and malignant transformation. No previous reports have indicated that a fistula may develop between a uterine fibroid and the bowel loops, although previous studies have documented the occurrence of fistulas from the uterus to the bowel following myomectomy or uterine artery embolization performed to treat a myoma. In our case report, we document the rare complication of a fistula occurring between a degenerated myoma in the posterior wall and the ileum 1 week postoperatively in a patient who underwent a Caesarean section but did not have a history of uterine artery embolization.

• Clinical and Experimental Reproductive Medicine
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• 제48권1호
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• pp.91-94
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• 2021

A 28-year-old woman presented with a 1-year history of severe progressive dysmenorrhea following suction evacuation and tubal ligation. Sonography showed a bicornuate uterus with hematometra in the left horn. Hysteroscopy ruled out a diagnosis of a congenital Müllerian anomaly, as both ostia appeared normal. Under laparoscopy, a mass was seen on the left fundal region near the insertion of the round ligament, and needle aspiration of a chocolate-colored fluid confirmed the diagnosis of an adenomyotic cyst. The cyst was excised. The patient recovered well and has been symptom-free since surgery. Adenomyotic cyst is a rare entity in young women and must be differentiated from obstructive Müllerian anomaly. Laparoscopy is the preferred minimally invasive modality for managing this rare disorder.

• 대한수의학회지
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• 제62권2호
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• pp.11.1-11.4
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• 2022

A captive female capybara (Hydrochoerus hydrochaeris) of unknown age discharged a bloody mass from the vaginal region. A histopathology examination revealed the mass to be a reproductive leiomyosarcoma, and an ovariohysterectomy was performed. The histopathology examination confirmed that the excised tissue was a uterine leiomyosarcoma. The purpose of this report is to describe clinical history and histopathological diagnosis of leiomyosarcoma in capybaras. This report is novel because it describes the first diagnosis of uterine leiomyosarcoma in a capybara. Since clinical data about capybaras are rare, this case report will help to diagnosis and treat reproductive diseases of this species.

• Journal of Ecology and Environment
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• 제30권4호
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• pp.319-324
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• 2007

To investigate the impacts of transgenic rice on freshwater organisms, we conducted two life table experiments using Daphnia magna for fifteen and twenty days, respectively. We examined life history traits such as population growth rates (r), reproductive rates ($R_0$), generation times, and survivorship. In the first experiment, we used non-drought-stressed transgenic and non-transgenic rice harvested in 2005. In the second study, we used non-transgenic and transgenic rice harvested in 2006 following drought stress. Each experiment involved three treatments in which D. magna neonates were fed with Selenastrum capricornutum (control treatment) and S. capricornutum with 5% aqueous extracts of non-transgenic rice (N-T) and transgenic rice (T). In the first experiment, D. magna showed reduced population growth rates and lowered fecundity in the N-T and T treatments. In the second experiment, D. magna receiving both transgenic and non-transgenic rice extracts showed very high mortality, low population growth rates and reproduction rates. We could not detect any significant negative effects of extracts from transgenic rice on D. magna life history traits at 95%.

• Clinical and Experimental Reproductive Medicine
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• 제37권3호
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• pp.231-237
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• 2010

목 적: 반복적 유산 또는 반복적 착상실패 환자의 T 림프구의 Th1 면역반응 정도를 알아보고, T 림프구 활성 정도를 분석하고자 하였다. 연구방법: 반복적 유산 및 반복적 착상실패를 경험한 37명의 환자를 연구군으로 설정하고, 유산이나 불임의 병력이 없이 정상분만의 경력이 있는 11명의 가임 여성을 대조군으로 모집하였다. 유세포분석기를 이용하여, 이들의 말초혈액 중 T helper 세포 내 TNF-$\alpha$와 INF-$\gamma$ 및 IL-10의 발현도를 측정하고 Th1/Th2 세포 비율 (TNF-$\alpha$/IL-10 및 INF-$gamma$/IL-10 발현도)을 계산하여 Th1 면역반응의 우세 정도 및 T 림프구의 활성도를 분석하였으며, 활성 표지자인 CD154와 CD69 발현 정도를 비교하였다. 결 과: 연구군의 평균연령은 $35.3{\pm}4.3$세였으며, 이들에서 T helper cell 내 TNF-$\alpha$/IL-10의 발현 비율이 대조군에 비해 유의하게 높았고 ($42.1{\pm}2.3$ vs. $28.7{\pm}2.7$, p=0.002), CD154와 CD69의 발현율 또한 대조군에 비해 전반적으로 높았다. CD154의 경우, T helper cell ($1.7{\pm}0.5$ vs. $0.3{\pm}0.2$, p=0.038)과 T suppressor cell ($0.6{\pm}0.2$ vs. $0.1{\pm}0.0$, p=0.024) 모두에서 유의하게 높은 발현을 보인 반면, CD69의 경우, 전체 T 림프구 ($5.6{\pm}1.9$ vs. $1.3{\pm}5.4$, p=0.046)와 T suppressor cell ($4.8{\pm}1.3$ vs. $1.8{\pm}0.2$, p=0.035)에서 통계적으로 높은 발현을 확인할 수 있었다. 결 론: 반복적 유산 및 반복적 착상실패를 보이는 여성에서 T 림프구의 활성도와 Th1 면역반응이 증가하였으며 이는, 이들 여성에서 활성화된 T 림프구가 Th1 면역반응을 유도하여 초기 임신의 유지와 착상에 좋지 않은 영향을 미치기 때문으로 생각된다.

• 생태와환경
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• 제33권3호통권91호
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• pp.282-294
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• 2000

버들붕어, M. chinensis를 실험실에서 사육하면서, 생식생태와 초기생활사를 조사한 결과는 다음과 같다. 성적으로 성숙한 수컷은 수표면에 기포소를 만들고 세력권을 형성하였으며, 암컷을 기포소 밑으로 유인한 후, 180$^{\circ}$ 회전한 자세로 산란과 방정을 하였다. 산란 행동은 1${\sim}$3시간 동안 계속되었으며, 수컷은 산란직 후부터 자어가 기포소를 벗어날 때까지 보호행동을 하였다. 다양한 수온 조건 중, 28$^{\circ}C$에서 산란 횟수와 산란수가 가장 많았으며, 난의 부화율은 26$^{\circ}C$에서 가장 높게 나타났다. 난은 투명하고 부성이었으며, 물 흡수 후 난의 크기는 0.95${\sim}$1.05 mm, 난황은 0.75${\sim}$0.80mm였다. 수온 26.0${\pm}$1$^{\circ}C$에서 난할은 약 15분 간격으로 진행되었으며, 42${\sim}$44시간만에 부화되었다 (전장 3.0${\sim}$3.2 mm). 부화 후 4${\sim}$5일 (전장 4.5${\sim}$5.4 mm)부터 먹이를 섭취하고 기포소 밖으로 흩어져 독립생활을 시작하였으며, 약 40${\sim}$45일 (전장 18.2${\sim}$23.5 mm)에는 치어기에 달하였다. 부화 후 90~110일에는 전장이 37.4${\sim}$48.2mm로 체형이 성어와 같아지고, 45.0 mm 이상의 개체들은 이차성징이 나타나 성구별이 가능하였으며, 전장 50.0 mm 전, 후에 달하는 약 120일 이후에는 산란에 이르렀다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.139-146
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• 2012

Obese postmenopausal women increase their risk of developing breast cancer (BC), in particular if they display an android-type pattern of adiposity, which is also associated to increased risks of diabetes mellitus, hypertension and cardiovascular disease. In order to explore the associations among anthropometry (body mass index, body composition, somatotype), some specific items of medical history (diabetes, hypertension, dislypidemias, hyperuricemia) and the risk of BC in Uruguayan women, a case-control study was carried out between 2004-2009 at our Oncology Unit. 912 women of ages between 23-69 years (367 new BC cases and 545 non hospitalized, age-matched controls with a normal mammography) were interviewed. Twenty body measurements were taken in order to calculate body composition and somatotype. Patients were queried on socio-demographics, reproductive history, family history of cancer, a brief food frequency questionnaire and on personal history of diabetes, dislypidemias, hyperuricemia, hypertension and gallbladder stones. Uni- and multivariate analyses were done, generating odds ratios (ORs) as an expression of relative risks. A personal history of diabetes was positively associated to BC risk (OR=1.64, 95% CI 1.00-2.69), being higher among postmenopausal women (OR=1.92, 95% CI 1.04-3.52). The risks of BC for diabetes in postmenopausal women with overweight combined with dislypidemia (OR=9.33, 95% CI 2.10-41.5) and high fat/muscle ratio (OR=7.81, 95% CI 2.01-30.3) were significantly high. As a conclusion, a personal history of diabetes and overweight was strongly associated to BC. The studied sample had a subset of high-risk of BC featured by postmenopausal overweight and diabetic women, who also had a personal history of hypertension and/or dyslipidemia. The present results could contribute to define new high risk groups and individuals for primary as well as for secondary prevention, since this pattern linked to the metabolic syndrome is usually not considered for BC prevention.