• 산업진흥연구
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• 제6권3호
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• pp.19-24
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• 2021

과학적 품질경영을 하기 위해서는 측정시스템에 문제가 없어야 한다. 이에 본 논문에서는 측정과정 중 측정결과에 영향을 미칠 수 있는 요인들이 무엇인지 확인하여 측정결과가 위치와 변동 면에서 문제점이 발생할 때 이를 야기하는 요인을 나열하고자 한다. 측정시스템의 변동은 크게 위치와 산포의 두 가지 속성으로 묘사되는데, 위치와 관련된 속성으로는 정확성, 안정성, 직선성이 있고, 산포와 관련된 속성으로는 재현성과 반복성이 있다. 측정시스템분석에서는 산포와 관련된 요소를 분석하는 것이 R&R분석인데, 여기서 반복성과 재현성의 크기는 여러 차례의 측정치간 차이인 범위와 측정자간 차이인 범위로 나타내며, 이들 범위를 이용한 99%의 산포로 그 크기를 파악한다. 측정시스템분석은 R&R분석이외에 실험계획을 활용하여 측정치의 변동을 유발하는 요인의 변동의 크기를 추정할 수 있다. 이때 변동을 야기하는 요인인 작업자와 제품이 랜덤요인인지 또는 고정요인인지 점검하여 그에 맞게 각 요인의 변동의 크기를 구해야 적절한 분석이 이루어진다.

• 치과방사선
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• 제24권2호
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• pp.347-359
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• 1994

The reproducibility of cephalography in repeated exposures were studied by tracing and photographic subtraction. The materials consisted of 50 pairs of 'same day' radiograph taken under identical conditions. The evaluation included skull, cervical column, hyoid bone, pharynx, tongue, soft tissue profile resulting 43 items in tracing, and 19 items in photographic subtraction. The results obtained from the differences between each pair were as follows: 1. The means and standard deviations by tracing of skull, cervical column, hyoid bone, pharynx, tongue, soft tissue profile were 0.34±0.62㎜, 1.02±1.59㎜, 1.37±1.78㎜, 0.55±1.16㎜, 0.51±1.51㎜, 0.15±0.3㎜ each. 2. The means and standard deviations by photographic subtraction of skull, cervical column, hyoid bone, pharynx, tongue were 0.09±0.35㎜, 0.70±0.95㎜, 1.22±1.33㎜, 0.53±0.86㎜, 0.27±0.41㎜ each.

• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제52권10호
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• pp.441-446
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• 2003

The chemical mechanical polishing (CMP) process is now widely employed in the ultra large scale integrated (ULSI) semiconductor fabrication. Especially, shallow trench isolation (STI) has become a key isolation scheme for sub-0.13/0.10${\mu}{\textrm}{m}$ CMOS technology. The most important issues of STI-CMP is to decrease the various defects such as nitride residue, dishing, and tom oxide. To solve these problems, in this paper, we studied the planarization characteristics using slurry additive with the high selectivity between $SiO_2$ and $Si_3$$N_4$ films for the purpose of process simplification and in-situ end point detection. As our experimental results, it was possible to achieve a global planarization and STI-CMP process could be dramatically simplified. Also, we estimated the reliability through the repeated tests with the optimized process conditions in order to identify the reproducibility of STI-CMP process.

• 한국해안·해양공학회논문집
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• 제34권6호
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• pp.177-187
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• 2022

본 연구는 2020년 해양수산부에서 제시한 개정된 천해설계파 추산방법인 바람장을 이용하여 부산항 신항을 대상으로 태풍 내습 시 설계파를 추산하고 파랑 관측자료와의 검증을 통해서 신뢰할 수 있는 천해설계파 산출방법을 제안하였다. 부산항 신항에 영향을 미친 태풍에 대해서 현업에서 일반적으로 많이 사용하고 있는 태풍 바람장과 SWAN 수치모델을 이용하여 태풍파를 추산한 결과 태풍 KONG-REY(1825), MAYSAK(2009)을 제외하고 재현성이 불량한 것으로 나타났다. 특히 부산항 신항에 가장 크게 영향을 미쳤던 태풍 MAEMI(0314)의 경우 최대유의 파고가 파랑 관측치에 비해서 약 35.0% 작게 추산되었다. 이에 바람장을 보정한 방법과 Boussinesq 방정식 수치모델을 이용하는 방법을 각각 적용하여 태풍파 재현성 개선방안을 검토하였다. 검토결과 바람장을 보정한 경우는 바람장 보정전과 동일하게 재현성이 떨어지는 것으로 나타났으나, 바람장 자료와 SWAN 모델 실험결과 그리고 Bou ssinesq 수치모델을 연계하는 방법으로 태풍 MAEMI(0314) 내습 시 태풍파를 추산한 결과 파랑 관측치와 최대유의파고가 유사하게 나타나 재현성이 양호한 것으로 검토되었다.

• 대한한의진단학회지
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• 제10권2호
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• pp.88-103
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• 2006

Objectives : We performed this study to search the best time for HRV measuring and which index has the validity in a short term measuring. Methods : At first, three examiner measured electrocardiogram(ECG) of 5 people(4 male + 1 female) for 20 minutes in two times. and we devided ten regions (0-5, 5-10, 10-15, 15-20, 0-10, 0-15, 0-20, 5-15, 10-20, 5-20 minutes). After that we finded the HRV index for each regions. To evaluate the validity, we used Gage Repeatability and Reproducibility Study by MINITAB(ver. 13.20). If the '%Study Var' is under 30 and 'Number of Distinct Categories' is over 4, we could tell it has validity(repeatability and reproducibility). Results : 1) The region and HRV index has repeatability and reproducibility, was HF index in 10-15 minutes. The HF index in 15-20 minutes gained 27.41(%Study Var) and 5(Number of Distinct Categories). 2) The HF index in 10-15 minutes has the better reproducibility than repeatability. The value of measurement is under the control. There is consistency among the examiner. The distribution of measurement is not large. There is no interaction between examiner and each people. 3) The HF index in 10-15, 0-10, 0-15, 0-20, 10-20 minutes was not enough to gain the repeatability and reproducibility. But it had some meanings ; %Study Var, Number of Distinct Categories is 32.68, 4 for 10-15 minutes, 34.43, 4 for 0-10 minutes, 34.44, 4 for 0-15 minutes, 33.56, 4 for 0-20 minutes, 32.07, 4 for 10-20 minutes. Conclusions : This study shows the best index of measuring HRV is the HF index in 15-20 minutes. So, from now on we should measure the HRV for 20 minutes and extract the HF index in 15-20 minutes. It must be the standard for HRV measuring.

• 분석과학
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• 제36권1호
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• pp.12-21
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• 2023

Protein glycation is vital to aging and disease. However, glycated proteins are low-abundant in plasma, rendering them difficult to identify using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Many studies have analyzed glycated peptides with high reproducibility. Here, glycated peptides in human serum were analyzed by LC-MS/MS using data-dependent acquisition (DDA) and parallel reaction monitoring (PRM). Boronic acid (BA) enrichment of in vitro glycated human serum peptides was performed. BA enrichment identified the most glycated peptides, and the glycated peptides of the more diversified proteins, excluding albumin, were analyzed. In PRM, glycated albumin PSMs were the most common, and this method exhibited the best reproducibility. The results of this study could help compare methods for identifying glycation-related biomarkers.

• 대한의생명과학회지
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• 제14권2호
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• pp.115-118
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• 2008

Salmonella typhi is frequent causes of foodborne illness and its detection is important for monitoring disease progression. In this study, by using general PCR and novel LAMP (Loop Mediated Isothermal Amplification) assay, we evaluated the usefulness of LAMP assay for detection of Salmonella typhi. In this LAMP assay, forward inner primer (FIP) and back inner primer (BIP) was specially designed for recognizing target invA gene. Target DNA was amplified and visualized as ladder-like pattern of bands on agarose gel within 60 min under isothermal conditions at $65^{\circ}C$. When the sensitivity and reproducibility of LAMP were compared to general PCR, there was no difference of reproducibility but sensitivity of LAMP assay was more efficient than PCR (the detection limit of LAMP assay was 30 fg, while the PCR assay was 3 pg). These results indicate that the LAMP assay is a potential and valuable means for detection of Salmonella typhi, especially for its rapidity, simplicity and low cost.

• Journal of Korean Dental Science
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• 제15권1호
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• pp.1-8
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• 2022

Purpose: Intraoral scanners, desktop scanners, and cone-beam computed tomography (CBCT) are being used in a complementary way for diagnosis and treatment planning. Limited patient-based results are available about dimensional reproducibility among different three-dimensional imaging systems. This study aimed to evaluate dimensional reproducibility among patient-derived digital models created from an intraoral scanner, desktop scanner, and two CBCT systems. Materials and Methods: Twenty-nine arches from sixteen patients who were candidates for implant treatments were enrolled. Different types of CBCT systems (KCT and VCT) were used before and after the surgery. Polyvinylsiloxane impressions were taken on the enrolled arches after the healing period. Gypsum casts were fabricated and scanned with an intraoral scanner (CIOS) and desktop scanner (MDS). Four test groups of digital models, each from CIOS, MDS, KCT, and VCT, respectively, were compared to the reference gypsum cast group. For comparison of linear measurements, intercanine and intermolar widths and left and right canine to molar lengths were measured on individual gypsum cast and digital models. All measurements were triplicated, and the averages were used for statistics. Bland-Altman plots were drawn to assess the degree of agreement between each test group with the reference gypsum cast group. A linear mixed model was used to analyze the fixed effect of the test groups compared to the reference group (α=0.05). Result: The Bland-Altman plots showed that the bias of each test group was -0.07 mm for CIOS, -0.07 mm for MDS, -0.21 mm for VCT, and -0.25 mm for KCT. The linear mixed model did not show significant differences between the test and reference groups (P>0.05). Conclusion: The linear distances measured on the digital models created from CIOS, MDS, and two CBCT systems showed slightly larger than the references but clinically acceptable reproducibility for diagnosis and treatment planning.

• Imaging Science in Dentistry
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• 제45권1호
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• pp.15-22
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• 2015

Purpose: This study was performed to assess the reproducibility of identifying the sella turcica landmark in a three-dimensional (3D) model by using a new sella-specific landmark reference system. Materials and Methods: Thirty-two cone-beam computed tomographic scans (3D Accuitomo$^{(R)}$ 170, J. Morita, Kyoto, Japan) were retrospectively collected. The 3D data were exported into the Digital Imaging and Communications in Medicine standard and then imported into the Maxilim$^{(R)}$ software (Medicim NV, Sint-Niklaas, Belgium) to create 3D surface models. Five observers identified four osseous landmarks in order to create the reference frame and then identified two sella landmarks. The x, y, and z coordinates of each landmark were exported. The observations were repeated after four weeks. Statistical analysis was performed using the multiple paired t-test with Bonferroni correction (intraobserver precision: p<0.005, interobserver precision: p<0.0011). Results: The intraobserver mean precision of all landmarks was <1 mm. Significant differences were found when comparing the intraobserver precision of each observer (p<0.005). For the sella landmarks, the intraobserver mean precision ranged from $0.43{\pm}0.34mm$ to $0.51{\pm}0.46mm$. The intraobserver reproducibility was generally good. The overall interobserver mean precision was <1 mm. Significant differences between each pair of observers for all anatomical landmarks were found (p<0.0011). The interobserver reproducibility of sella landmarks was good, with >50% precision in locating the landmark within 1 mm. Conclusion: A newly developed reference system offers high precision and reproducibility for sella turcica identification in a 3D model without being based on two-dimensional images derived from 3D data.

• 품질경영학회지
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• 제42권4호
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• pp.607-616
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• 2014

Purpose: This paper reviews popular measurement system indices and proposes a procedure for assessing a measurement system using two parameters with intraclass correlation and a factor for process capability. Methods: Gage Repeatability and Reproducibility(GR&R), precision-to-tolerance ratio(PTR), number of distinct categories, producer's and consumer's risks are employed to assess the measurement capabilities and discuss the relationships between measurement system metrics. Results: Two-dimensional plot by two parameters is presented to assess adequacy of the measurement system and process capability. A numerical example and previously studied case study are provided for illustration. Conclusion: The procedure proposed in this paper using two-dimension parameters provides a valuable procedure and helpful guidelines to quality and production managers in assessing the capabilities of a measurement system and choosing the needed actions to be the most benefit.