• Title/Summary/Keyword: Reproducibility of result

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Analysis of Chloride Content in Aqueous Solution and Mortar using Laser Induced Breakdown Spectroscopy (LIBS를 활용한 수용액과 모르타르 내 염화물량 분석)

  • Ryu, Hwa-Sung;Park, Won-Jun
    • Journal of the Korea Institute of Building Construction
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    • v.21 no.3
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    • pp.189-194
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    • 2021
  • LIBS has been attracting attention as an analytical method capable of real-time measurement without sample preparation. In this study, a Lab. scale LIBS device was fabricated to examine the applicability and reproducibility of LIBS in the analysis of chloride contents in mortar. The existing analysis method and LIBS analysis were performed simultaneously on the mortar test specimen with the chloride content adjusted. Compared to the chloride content condition of the mortar, the XRF and Potentiometric Titration results also showed a similar trend. As a result of LIBS analysis, chlorine ions were detected at a wavelength of 837.59 nm according to the chloride content condition. In order to improve the precision in various concentration ranges, the LIBS signal amplification of about 50 times through the electric field enhancement was implemented. Through the verification of the aqueous solution-based reproducibility, a high correlation between the LIBS signal strength and the Cl concentration was confirmed, and the possibility of applying LIBS to the durability diagnosis of concrete damage by chloride was confirmed.

Clinical validation of ImmuneCheck IgE for the rapid detection of serum total IgE (총 IgE의 신속한 정량 측정을 위한 ImmuneCheck IgE의 임상적 유용성)

  • Lee, Shinhaeng;Choi, Jinyoung;Choe, Eunju;Lee, Sang Chul;Park, Kyung Hee;Lee, Jae-Hyun;Park, Jung-Won
    • Allergy, Asthma & Respiratory Disease
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    • v.6 no.6
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    • pp.310-314
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    • 2018
  • Purpose: Conventional serum IgE assay was costly, required the skills of expert, and relied heavily on expensive equipment. Quantitative measurement of total IgE using Point of Care Test (POCT) device can be the solution for these limitations. This study evaluated and validated the reproducibility of ImmuneCheck IgE. Methods: This study included 120 patients of allergic diseases such as allergic rhinitis, asthma, drug allergy, food allergy, atopic dermatitis, or anaphylaxis. The reliability of POCT ImmuneCheck IgE was evaluated by comparing results from the naked eye and from the Q-Reader. Intratest reproducibility and intertest correlation were analyzed using intraclass correlation coefficient (ICC). Results: Of the 120 enrolled patients, 51 were males and 69 were females. The ages ranged from 19 to 84 years, with an average age of 51.5 years. The concentration of serum total IgE measured by Phadia ImmunoCAP IgE ranged from 5.95 to 5,000 IU/mL. ICC for Intratest reproducibility of ImmuneCheck IgE by naked eye and by Q-Reader were 0.991 (P< 0.001) and 0.989 (P< 0.001), respectively. In addition, intertest correlation between ImmuneCheck IgE and Phadia ImmunoCAP IgE results of naked eye and Q-Reader were 0.968 (P< 0.001) and 0.948 (P< 0.001), respectively. Conclusion: The ImmuneCheck IgE was reproducible and highly correlated with conventional Phadia ImmunoCAP IgE assay. This result suggests that ImmuneCheck IgE can be a useful tool for rapid and precise detection of total IgE.

Development of RMRD and Moving Phantom for Radiotherapy in Moving Tumors

  • Lee, S.;Seong, Jin-Sil;Chu, Sung-Sil;Yoon, Won-Sup;Yang, Dae-Sik;Choi, Myung-Sun;Kim, Chul-Yong
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2003.09a
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    • pp.63-63
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    • 2003
  • Purpose: Planning target volume (PTV) for tumors in abdomen or thorax includes enough margin for breathing-related movement of tumor volumes during treatment. We developed a simple and handy method, which can reduce PTV margins in patients with moving tumors, respiratory motion reduction device system (RMRDs). Materials and Methods: The patients clinical database was structured for moving tumor patients and patient setup error measurement and immobilization device effects were investigated. The system is composed of the respiratory motion reduction device utilized in prone position and abdominal presser (strip device) utilized in the supine position, moving phantom and the analysis program, which enables the analysis on patients setup reproducibility. It was tested for analyzing the diaphragm movement and CT volume differences from patients with RMRDs, the magnitude of PTV margin was determined and dose volume histogram (DVH) was computed using a treatment planning software. Dose to normal tissue between patients with RMRDs and without RMRDs was analyzed by comparing the fraction of the normal liver receiving to 50% of the isocenter dose(TD50). Results: In case of utilizing RMRDs, which was personally developed in our hospital, the value was reduced to $5pm1.4 mm$, and in case of which the belt immobilization device was utilized, the value was reduced to 3$pm$0.9 mm. Also in case of which the strip device was utilized, the value was proven to reduce to $4pm.3 mm$0. As a result of analyzing the TD50 is irradiated in DVH according to the radiation treatment planning, the usage of the respiratory motion reduction device can create the reduce of 30% to the maximum. Also by obtaining the digital image, the function of comparison between the standard image, automated external contour subtraction, and etc were utilized to develop patients setup reproducibility analysis program that can evaluate the change in the patients setup. Conclusion: Internal organ motion due to breathing can be reduced using RMRDs, which is simple and easy to use in clinical setting. It can reduce the organ motion-related PTV margin, thereby decrease volume of the irradiated normal tissue.

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Case Series Reporting 7 Somatic Symptom Disorder Cases Diagnosed as Greater Yin Disease by Shanghanlun Provisions (『상한론(傷寒論)』 태음병(太陰病)으로 진단된 신체증상장애 환자 7례 증례 보고)

  • Yun, Hyo-joong;Ha, Hyun-yee;Doo, In-sun;Lee, Sung-in;Lee, Sung-Jun
    • 대한상한금궤의학회지
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    • v.13 no.1
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    • pp.45-59
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    • 2021
  • Objectives: This study was conducted to confirm the reproducibility of the diagnosis of greater yin disease (太陰病) and the efficacy of herbal treatment using Gyejigajakyak-tang or Gyejigadaehwang-tang in somatic symptom disorder (SSD). We also further refined the characteristics of greater yin disease in SSD. Methods: We analyzed the demographic and treatment data of seven patients with SSD from four Korean medical clinics. The reliability of diagnosis and the efficacy of the treatments were evaluated by the Beck Anxiety Inventory (BAI), a numerical rating scale (NRS), and the patients' statements. Finally, we analyzed patients according to the diagnostic points of Shanghanlun provision 273. Results: Seven SSD patients took Gyejigajakyak-tang or Gyejigadaehwang-tang. The mean age of the patients was 52.1±15.8 years old, and the herbal medication period was 82.2±38.2 days. At the first visit, the patients showed hypochondriasis, obvious stress, and a severe BAI score (40.4±10.9). The NRS significantly decreased from 8.9±1.6 to 0.7±0.7 after the treatments. There were no side effects reported. As a result of analyzing these 7 cases, hypochondriasis, obvious stress, and anxiety were identified, which had been previously suggested as 自痛, 因爾, and 結硬. Conclusions: We confirmed the reproducibility of greater yin disease in 7 SSD cases from 4 medical institutions. These results imply that there could be a considerable relation between SSD and greater yin disease as defined by the Shanghanlun provisions.

Eco-Friendly Design Characteristics of Stella McCartney's Knit Design (스텔라 맥카트니 니트 디자인에 표현된 친환경 디자인 특성)

  • Lee, Younhee;Park, Sun-Hee
    • Journal of the Korea Fashion and Costume Design Association
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    • v.24 no.3
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    • pp.17-31
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    • 2022
  • The purpose of this research is to suggest diverse directions for eco-friendly knit designing through analyzing the characteristics of Stella McCartney's knit designs. The first stage of the research was to explore the characteristics of eco-friendly fashion design based on literature review. The next stage was to categorize the characteristics of eco-friendly design found in Stella McCartney' knit fashion based on the precedent analysis. The data collected showed 274 examples from 40 Stella McCartney collections, including Spring, Resort, Pre-Fall, and Fall Ready-to-wear collections between 2013 and 2022. All information was collected using www.vogue.com. As a result, the characteristics of Stella McCartney's knit design were classified into four directopms: 1) Perpetual Naturalism, 2) Cultural Complexity, 3) Practical Functionality, and 4) Subcultural Reproducibility. The first characteristic, 'Perpetual Naturalism' values the continuous symbiosis between animals and human beings, thereby protecting global environmental value. Stella McCartney's knit design continuously showed a longing for nature's beauty through fashion design, which allowed people to enjoy the meaning of symbiosis between human beings and animals. Second, 'Cultural Complexity' is the characteristic that appears in Stella McCartney's knit fashion design when collaborating with various artists and/or mixing traditional knit motives inspired by traditional cultures and retro moods. Third, 'Practical Functionality' is the design characterisitic that allows items to be worn for a long time as it is comfortable, simple, and practical. Stella McCartney's knit designs pursue easy-to-wear designs that are comfortable and have practical designs with simple details. Lastly, 'Subcultural Reproducibility' showed in Stella McCartney's knit designs reflect Hippie culture, which pursued a rejection of conventional values, and promoted sustainable energy. This culture peaked in the 1960s and 1970s, when 'Beatles' were mainly working. Additionally, retro styled knit designs inspired by other various music genres from the 1980s and 1990s appeared in this category as well.

Continuous Coating Process Development for PEFC Membrane Electrode Assembly (고분자 연료전지용 MEA 연속 코팅공정 개발)

  • Park, Seok-Hee;Yoon, Young-Gi;Kim, Chang-Soo;Lee, Won-Yong
    • 한국신재생에너지학회:학술대회논문집
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    • 2006.06a
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    • pp.110-112
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    • 2006
  • Membrane electrode assembly (MEA) for polymer electrolyte fuel cell (PEFC) are commonly prepared in the research laboratory by spraying, screen-printing and brushing catalyst slurry onto membrane or other support material like carbon paper or polyimide film in a batch style. These hand applications of the catalyst slurry are painstaking process with respect to precision of catalyst loading and reproducibility. It has been generally mentioned that the adoption of continuous process is very helpful to develop the reliable product. In the present work, we report the results of using continuous type coater with doctor-blade to coat catalyst slurry for preparing the MEA catalyst layers In a faster and highly reproducible fashion. We show that while expectedly faster than batch style, the machine coater requires the use of slurry of appropriate composition and a properly selected transfer decal material in order to achieve superior MEA plat lnw loading reproducibility. To make highly viscous catalyst slurry that is imperative for using coater, we use 40wt.% Nafion solution and minimize the content of organic solvent. And the choice of proper high surface area catalyst is important in the viewpoint of making well-dispersed slurry. After catalyst coating onto the support material, we transferred the catalyst layer to both sides of Nafion membrane by hot-pressing In this case, the degree of transfer was Influenced by hot-pressing condition including temperature, pressure, and time. To compare the transferring ability, we compared so many films and detaching papers. And among the support, polyethylene terephthalate(PET) film shows the prominent result.

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A study on the mold opening stroke according to the control method of the injection molding machine (사출성형기의 속도제어 방식에 따른 형개거리에 관한 연구)

  • Jung, Hyun-Suk;Lee, Chun-Kyu
    • Design & Manufacturing
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    • v.15 no.3
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    • pp.56-61
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    • 2021
  • The increase in automation facilities in the injection molding industry is a very important process control item. The most important item when constructing an unmanned machine using a take-out robot is the "mold opening stroke" of the mold. The injection molding machine control method is divided into hydraulic type and electric type, and there have been few studies on the mold opening distance according to the control method. In this study, the correlation was confirmed by increasing the injection speed to 20, 50, 80, and 100% for the three types of hydraulic control method, open loop and close loop, and electric control method. Through the experiment, the following results were obtained. (1) It can be seen that the reproducibility is excellent with the electric, close loop, and open loop control methods. (2) When the injection speed is set to 50%, the mold opening distance is 263.10~263.27 mm, which is the most reproducible. (3) As a result of ANOVA, both injection speed and mold opening distance showed a significant difference in the hydraulic control method (p<0.05), but it was verified through experiments that there was no significant difference in the electric control method. Based on these results, when electric control is selected rather than hydraulic control, the reproducibility of the mold opening distance is excellent, so it is thought that the taking-out robot can take the object out of the mold more safely.

Comparison of Meteorological Drought Indices Using Past Drought Cases of Taebaek and Sokcho (태백, 속초 과거 가뭄사례를 이용한 기상학적 가뭄지수의 비교 고찰)

  • Kang, Dong Ho;Nam, Dong Ho;Kim, Byung Sik
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.39 no.6
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    • pp.735-742
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    • 2019
  • Drought is a social phenomenon in which the degree of perception varies depending on the affected factors, and is defined as various relative concepts such as meteorological drought, hydrological drought, agricultural drought, and climatological drought. In this study, a comparative analysis of meteorological drought among variously defined droughts was conducted and the applicability of the drought index was examined by comparing the actual drought cases and the results of meteorological drought index analysis. In order to compare the drought index, we used standardized Precipitation Index (SPI), China-Z Index (CZI), Modified CZI (MCZI) and Z-Score Index Respectively. Four drought indices were used for the Taebaek and Sokcho areas. The drought index was analyzed using the meteorological data from 1986 to 2015 for a duration of 3 months. As a result of the analysis, the SPI drought index was analyzed to be highly reproducible for the case of drought with past limited water series. In the case of CZI and MCZI drought indices, the number of extreme dry occurrences is similar to that of the past cases, but the reproducibility is low for the actual drought years. In the case of ZSI drought index, it is analyzed that the number of occurrences and the comparison with the past cases are inferior in reproducibility. For the meteorological drought index using precipitation, it would be effective to use the SPI drought index with the highest reproducibility and the past drought case.

Analysis of the Effect of Objective Functions on Hydrologic Model Calibration and Simulation (목적함수에 따른 매개변수 추정 및 수문모형 정확도 비교·분석)

  • Lee, Gi Ha;Yeon, Min Ho;Kim, Young Hun;Jung, Sung Ho
    • Journal of Korean Society of Disaster and Security
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    • v.15 no.1
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    • pp.1-12
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    • 2022
  • An automatic optimization technique is used to estimate the optimal parameters of the hydrologic model, and different hydrologic response results can be provided depending on objective functions. In this study, the parameters of the event-based rainfall-runoff model were estimated using various objective functions, the reproducibility of the hydrograph according to the objective functions was evaluated, and appropriate objective functions were proposed. As the rainfall-runoff model, the storage function model(SFM), which is a lumped hydrologic model used for runoff simulation in the current Korean flood forecasting system, was selected. In order to evaluate the reproducibility of the hydrograph for each objective function, 9 rainfall events were selected for the Cheoncheon basin, which is the upstream basin of Yongdam Dam, and widely-used 7 objective functions were selected for parameter estimation of the SFM for each rainfall event. Then, the reproducibility of the simulated hydrograph using the optimal parameter sets based on the different objective functions was analyzed. As a result, RMSE, NSE, and RSR, which include the error square term in the objective function, showed the highest accuracy for all rainfall events except for Event 7. In addition, in the case of PBIAS and VE, which include an error term compared to the observed flow, it also showed relatively stable reproducibility of the hydrograph. However, in the case of MIA, which adjusts parameters sensitive to high flow and low flow simultaneously, the hydrograph reproducibility performance was found to be very low.

Evaluation on Reproducibility of Low-Dose Kidney Scan in Dynamic Kidney Scan (동적신장검사에서 저선량을 사용한 신장검사의 재현성 평가)

  • Lee, Jaesang;Lee, Kyuchan;Lee, Seunghwan;Bae, Seongbok;Park, Jongyeop
    • The Korean Journal of Nuclear Medicine Technology
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    • v.20 no.1
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    • pp.59-65
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    • 2016
  • Purpose Dynamic kidney scan is a typical imaging technique that visualizes kidney function. Reproducibility of dynamic kidney scans has been evaluated by comparing low-dose kidney scans with low-dose radiopharmaceutical and standard dynamic kidney scan. With this comparative study, if reproducibility is superb, the dynamic kidney scan method with reduced radioactivity to patients is to be utilized and radiation exposure to patient is to be reduced. Materials and Methods For gamma camera, Orbiter, SymbiaE (Siemens, Germany) was used. Among patients who had used 370 Mbq (10 mCi) from January of 2013 to February 2014 and other patients who had used 185 Mbq (5 mCi) from March of 2014 to July of 2015 with identical condition, 21 subjects using DTPA and 20 subjects using $MAG_3$, 41 subjects in total, had been selected as subjects for data. From renogram of the result image, frame of the peak point was selected. Then, region of interest of kidney and background had been selected and Kidney to Background Ratio has been calculated for comparison. Results In tests using DTPA, kidney to background ratio when using 370 Mbq was $5.67{\pm}0.8$ at average while it was $5.62{\pm}0.87$ when using 185 Mbq, which didn't show much difference. Also in the tests using $MAG_3$, kidney to background ratio when using 370 Mbq was $14.95{\pm}2.58$ at average and $14.56{\pm}2.02$ in 185 Mbq, which neither showed much difference. In paired sample t-test, p-value was 0.566 in DTPA and 0.363 in $MAG_3$, which confirmed that there was no difference between the groups. Conclusion In identical patients, when dose was decreased from 370 Mbq to 185 Mbq, reproducibility of dynamic kidney scan was proven to be excellent. Low-dose Dynamic kidney scan can achieve results with fine reproducibility without improvement in performance of gamma camera and is expected to reduce radiation exposure to patient.

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